HealthyBPIT 5-LineNCT07296640

BPIT 5-Line Pilot: Interventional Study on Strength, HRV & Injury Risk Reduction (n=23)

A study testing BPIT 5-Line Training in people with Healthy, run by MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. at 1 site in India.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

This prospective, single-center, interventional pilot (n=23) evaluates the 5-Line Principle of Balanced Intensity Training (BPIT) over 6 weeks at GFFI Fitness Academy. Participants (18 males aged 22-48, 5 females aged 20-33) will receive BPIT 5-Line Training (3 sessions/week, 6 weeks). No control group. Read more about this study

Who is it for?: Ages 22 to 65 yearsHealthy volunteers can take part
Conditions the study is for: Healthy
What is being tested?: BPIT 5-Line Training
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 23 participants
Where: 1 siteIndia
Study dates: 1 Jul 2024to 30 Nov 2024
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 22 to 65 years
All sexes
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

Healthy adults aged 22-65 years
Regular fitness trainees (≥2 sessions/week prior)
Able to provide informed consent
No recent musculoskeletal injury (past 3 months)

Who cannot join

- Cardiovascular disease or uncontrolled hypertension
Current musculoskeletal injury or surgery (past 6 months)
Neurological disorders affecting movement
Pregnancy
Use of performance-enhancing substances

Trial locations and contacts

1 site in 1 country.

India1 site

GFFI Fitness Academy
New Delhi, National Capital Territory of Delhi, 110026

Other trials in India

About this study

Official title: A Prospective, Single-Center, Interventional Study to Evaluate the 5-Line Principle of Balanced Intensity Training (BPIT) for Enhancing Physical Performance and Reducing Injury Risk

Progressive intensity via anatomical lines: 1. Ground-Based (Low Intensity); 2. Knee-Level (Low-Moderate); 3. Standing (Moderate); 4. Head-Level (Moderate-High); 5. Plyometric/High-Impact (High). Aims to assess changes in strength, HRV, and injury risk.

Read the detailed description

STUDY DESIGN: Prospective, single-center, interventional pilot (n=23) with single-group assignment. All participants receive the BPIT 5-Line intervention. Assessments at baseline and Week 6.

INTERVENTION: BPIT 5-Line Training: 3 x 60-minute sessions/week for 6 weeks, progressing across five intensity lines: 1. Ground-Based (Low Intensity, e.g., prone planks); 2. Knee-Level (Low-Moderate, e.g., shoulder press); 3. Standing (Moderate, e.g., half-squat); 4. Head-Level (Moderate-High); 5. Plyometric/High-Impact (High Intensity). Specific exercises detailed in Training Protocol Manual.

OBJECTIVES: Primary - Evaluate BPIT's impact on 1RM strength (e.g., squat, bench press, deadlift) and training-related injury incidence. Secondary - Assess changes in HRV (RMSSD), HRR (bpm in 60s), EMG muscle activation, joint biomechanics (knee valgus, spinal curvature), adherence (% sessions completed), and participant feedback (questionnaires).

Conditions: Healthy
Being tested: BPIT 5-Line Training

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

BPIT 5-Line TrainingBehavioural
All 23 participants received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 anatomical lines: 1. Ground-Based, Low Intensity; 2. Knee-Level, Low-Moderate; 3. Standing, Moderate; 4. Head-Level, Moderate-High; 5. Plyometric/High-Impact, High Intensity. Sessions 45-60 min, monitored via HRV, pain, fatigue.

Study groups in NCT07296640
Study group	Role	What they receive
BPIT 5-Line Training	Experimental	All 23 participants (18 males aged 22-48, 5 females aged 20-33) received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 Lines: 1. Ground-Based, Low Intensity 2. Knee-Level, Low-Moderate Intensity 3. Standing, Moderate Intensity 4. Head-Level, Moderate-High Intensity 5. Plyometric/High-Impact, High Intensity Receives: Behavioral: BPIT 5-Line Training

What is being measured

The primary outcome is the main question the study is designed to answer.

Change in 1RM Strength
Change in one-repetition maximum (1RM) strength for key exercises (e.g., squat, bench press) from baseline to week 6. Measured in kilograms (kg) using standard 1RM testing protocol.
Time Frame: Baseline to Week 6 Unit of Measure: kilograms (kg)
Measured: 6 weeks
Injury Incidence
Number of new musculoskeletal injuries reported during the study period, defined as any complaint requiring medical attention, training modification, or rest exceeding 1 day. Measured as incidence rate per 100 participant-weeks (normalized for exposure in this 23-participant pilot).
Unit of Measure: injuries per 100 participant-weeks
Measured: Baseline to Week 6

Secondary outcomes (6)

Change in Heart Rate Variability (HRV)
Change in Heart Rate Variability (RMSSD) from baseline to week 6, measured via 60-second daily monitoring using HRV device/app.
Time Frame: Baseline to Week 6 Unit of Measure: milliseconds (ms)
Measured: Week 6
Change in Muscle Activation (EMG Amplitude)
Change in Electromyography (EMG) amplitude for key muscle groups during specific exercises from baseline to week 6, measured as percentage of maximum voluntary contraction (%MVC) using EMG equipment.
Time Frame: Baseline to Week 6 Unit of Measure: percentage of maximum voluntary contraction (%MVC)
Measured: Baseline to Week 6
Change in Joint Biomechanics (Knee Valgus and Spinal Curvature)
Change in knee valgus and spinal curvature angles during functional movements from baseline to week 6, measured in degrees via 3D motion analysis or goniometer.
Time Frame: Baseline to Week 6 Unit of Measure: degrees
Measured: Baseline to Week 6
Training Adherence
Percentage of completed training sessions from baseline to week 6, measured via session logs.
Time Frame: Baseline to Week 6 Unit of Measure: percentage
Measured: Baseline to Week 6
Participant Feedback
Qualitative feedback from post-study questionnaires, scored on a Likert scale (1-5) for satisfaction and perceived benefit.
Time Frame: Week 6 Unit of Measure: units on a scale (1-5)
Measured: 6 weeks
Heart Rate Recovery (HRR)
Change in Heart Rate Recovery (bpm decrease in 60 seconds post-exercise) from baseline to week 6, measured via HR monitor.
Time Frame: Baseline to Week 6 Unit of Measure: beats per minute (bpm)
Measured: 6 Weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Jul 202430 Nov 2024

First posted22 Dec 2025
Study start1 Jul 2024
Primary completion30 Nov 2024
Study completion30 Nov 2024

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for HealthyStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 23 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07296640
Sponsor's protocol ID: BPIT-GFFI-2024-001
Other IDs: Other → MMSx Authority
Acronym: BPIT 5-Line
Status last verified: Dec 2025
First submitted: 18 Nov 2025
Last updated: 22 Dec 2025
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

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Study at a glance

From the registry record, last updated by the sponsor on 22 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: A Prospective, Single-Center, Interventional Study to Evaluate the 5-Line Principle of Balanced Intensity Training (BPIT) for Enhancing Physical Performance and Reducing Injury Risk
ClinicalTrials.gov ID: NCT07296640
Acronym / sponsor ID: BPIT 5-Line / BPIT-GFFI-2024-001
Conditions: Healthy
Study type: Interventional
Recruitment status: Completed
Enrolment: 23 participants (actual)
Lead sponsor: MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.University, hospital or other
Study start: 1 Jul 2024 (actual)
Primary completion: 30 Nov 2024 (actual)
Study completion: 30 Nov 2024 (actual)
First posted: 22 Dec 2025 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

STUDY DESIGN: Prospective, single-center, interventional pilot (n=23) with single-group assignment. All participants receive the BPIT 5-Line intervention. Assessments at baseline and Week 6.

Study design

Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1

Arm	Type	Receives
BPIT 5-Line Training	Experimental	Behavioral: BPIT 5-Line TrainingAll 23 participants (18 males aged 22-48, 5 females aged 20-33) received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 Lines: 1. Ground-Based, Low Intensity 2. Knee-Level, Low-Moderate Intensity 3. Standing, Moderate Intensity 4. Head-Level, Moderate-High Intensity 5. Plyometric/High-Impact, High Intensity

Who may qualify

Ages: 22 to 65 years
Sex: All
Healthy volunteers: Accepted
Age groups: Adult, Older adult

Key inclusion criteria (4 listed)

Healthy adults aged 22-65 years
Regular fitness trainees (≥2 sessions/week prior)
Able to provide informed consent
No recent musculoskeletal injury (past 3 months)

Key exclusion criteria (5 listed)

- Cardiovascular disease or uncontrolled hypertension
Current musculoskeletal injury or surgery (past 6 months)
Neurological disorders affecting movement
Pregnancy
Use of performance-enhancing substances

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
BPIT 5-Line TrainingAll 23 participants received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 anatomical lines: 1. Ground-Based, Low Intensity; 2. Knee-Level, Low-Moderate; 3. Standing, Moderate; 4. Head-Level, Moderate-High; 5. Plyometric/High-Impact, High Intensity. Sessions 45-60 min, monitored via HRV, pain, fatigue.	Behavioural	BPIT 5-Line Training

Primary outcome

Change in 1RM Strength
Time frame: 6 weeks
Change in one-repetition maximum (1RM) strength for key exercises (e.g., squat, bench press) from baseline to week 6. Measured in kilograms (kg) using standard 1RM testing protocol. Time Frame: Baseline to Week 6 Unit of Measure: kilograms (kg)
Injury Incidence
Time frame: Baseline to Week 6
Number of new musculoskeletal injuries reported during the study period, defined as any complaint requiring medical attention, training modification, or rest exceeding 1 day. Measured as incidence rate per 100 participant-weeks (normalized for exposure in this 23-participant pilot). Unit of Measure: injuries per 100 participant-weeks

6 secondary outcomes

Change in Heart Rate Variability (HRV)
Time frame: Week 6
Change in Muscle Activation (EMG Amplitude)
Time frame: Baseline to Week 6
Change in Joint Biomechanics (Knee Valgus and Spinal Curvature)
Time frame: Baseline to Week 6
Training Adherence
Time frame: Baseline to Week 6
Participant Feedback
Time frame: 6 weeks
Heart Rate Recovery (HRR)
Time frame: 6 Weeks

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 22 Dec 2025.
Complete Study Documentation Package - BPIT 5-Line Pilot (Protocol, Ethics, Consent, Logs, AE, Report, Closeout)Link provided by the sponsor.

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing BPIT 5-Line Training in people with Healthy, run by MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. at 1 site in India.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 22 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in India. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in 1RM Strength (time frame: 6 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07296640.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Dec 2025.