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Thyroid CancerNCT07298187

The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery

An observational study of Thyroid Cancer and Thyroid and Parathyroid Surgery, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

THE EFFECT OF HEAD POSİTİON ON THE OPTİC NERVE SHEATH DİAMETER İN PATİENTS DURİNG THYROİD SURGERY Read more about this study

Who is it for?
Ages 18 to 65 yearsHealthy volunteers can take part
How many people
49 participants
Where
1 siteTurkey (Türkiye)
Study dates
1 Apr 2025to 3 Nov 2025
How long will I take part?
7 Days
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 65 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Study population: ISTANBUL UNIVERSITY-CERRAHPASA

Who may be able to join

  • Patients aged between 18 and 65, with an ASA score between 1 and 2 according to the American Society of Anesthesiologists (ASA) physical status classification system
  • whose surgery duration was expected to be less than 4 hours were included in our study.

Who cannot join

  • liver failure
  • kidney failure
  • intracranial masses
  • history of hydrocephalus,
  • migraine
  • chronic hypoxemia or hypercarbic lung disease
Show all 16Show fewer
  • additional heart disease
  • hemodynamic insufficiency
  • neurological and psychiatric diseases,
  • glaucoma
  • patients in whom ocular USG could not provide adequate images
  • patients with pathological problems involving the eyelid and its surrounding area
  • patients with diseases such as periorbital cellulitis
  • patients with preoperative headache complaints
  • patients with known diseases that could cause increased intracranial pressure
  • patients who refused to participate in the study were excluded from the study.

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

  • Istanbul University Cerrahpasa

    Istanbul, FATİH, 34000

Other trials in Turkey (Türkiye)

About this study

THE EFFECT OF HEAD POSİTİON ON THE OPTİC NERVE SHEATH DİAMETER İN PATİENTS DURİNG THYROİD SURGERY

Read the detailed description

Aim: In thyroidectomy surgery, the patient's head is placed in hyperextension and the patient is placed in a semi-sitting position to facilitate access to the surgical site. This position of the head causes a decrease in venous return or partial obstruction of venous return due to stretching of the neck veins. The aim of our study is to demonstrate the effect of surgical position on intracranial pressure by measuring the optic nerve sheath diameter (OSSD) using ultrasonography in patients undergoing thyroid surgery and to determine its correlation with post-operative headaches.

Material And Method: Our study was conducted prospectively and randomly in patients undergoing elective total thyroidectomy. Patients aged 18-65 with an ASA score of 1-2 and an operation time of less than 4 hours were included in our study. Patients were positioned in the semi-Fowler position with a 30° extension of the head. Bilateral OSSD surgical positioning was applied, and after ensuring haemodynamic stability for 5 minutes and at the end of the operation, measurements were taken twice using ultrasound, and the average was recorded. The Visual Analogue Scale (VAS) was used to assess postoperative pain intensity. Headache was assessed and recorded at 15 minutes, 30 minutes, 1 hour, 24 hours, 3 days, and 7 days postoperatively.

Medical subject headings
Thyroid Neoplasms, Thyroid Diseases

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. OPTİC NERVE SHEATH DİAMETER

    CHANGE İN OPTİC NERVE SHEATH DİAMETER MEASURED BY ULTRASOUND BEFORE AND AFTER POSİTİONİNG DURİNG THYROİDECTOMY

    Measured: INTRAOPERATİVE PERİOD(FROM İNDUCTİON TO THE END OF SURGERY)

Secondary outcomes (1)

  1. POSTOPERATİVE HEADACHE SEVERİTY (VISUAL ANALOG SCALE)

    THE SEVERİTY OF POSTOPERATİVE HEADACHE WİLL BE ASSESSED USİNG A VİSUAL ANALOG SCALE. THE LOWEST POSSIBLE SCORE ON THE VISUAL ANALOG SCALE WAS 0, AND THE HIGHEST POSSIBLE SCORE WAS 10.

    Measured: WİTHİN SEVEN DAYS AFTER SURGERY

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted23 Dec 2025
  2. Study start1 Apr 2025
  3. Primary completion30 Sep 2025
  4. Study completion3 Nov 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Case only
Time perspective
Prospective
Enrolment
49 participants (actual)
Target duration
7 Days
IDs, dates and publications
ClinicalTrials.gov ID
NCT07298187
Sponsor's protocol ID
1274724
Status last verified
Dec 2025
First submitted
9 Dec 2025
Last updated
23 Dec 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: THE INDIVIDUAL PARTİCİPANT DATA WİLL NOT BE SHARED BECAUSE OF İNSTİTUTİONAL AND ETHİCAL RESTRİCTİONS

Questions about this trial

What is this clinical trial studying?

An observational study of Thyroid Cancer and Thyroid and Parathyroid Surgery, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 16 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 23 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

OPTİC NERVE SHEATH DİAMETER (time frame: INTRAOPERATİVE PERİOD(FROM İNDUCTİON TO THE END OF SURGERY)). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07298187.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Dec 2025.

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