Pectus Excavatum DeformityNCT07300748
Effectiveness of Cardiopulmonary Exercises for Children With Pectus Excavatum
A study testing Cardiopulmonary exercises at hospital and Pulmonary and posture exercises at home in people with Pectus Excavatum Deformity, run by Ankara Etlik City Hospital at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate the effects of cardiopulmonary rehabilitation on respiratory function, exercise tolerance and posture in patients with pectus excavatum. Read more about this study
- Who is it for?
- Ages 5 to 18 years
- Conditions the study is for
- Pectus Excavatum Deformity
- What is being tested?
- Cardiopulmonary exercises at hospital and Pulmonary and posture exercises at home
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 9 Dec 2025to 9 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 5 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Children aged 5-18 years with pectus excavatum deformity
- Children undergoing conservative treatment (vacuum orthosis, exercise)
- Patients whose families have signed a consent form agreeing to participate in the study
Who cannot join
- Known cardiac disease
- Presence of an additional syndrome (Marfan syndrome, etc.)
- Cobb angle ≥10°
- Refusal to participate in the study
- Presence of mixed deformity (pectus arcuatum)
- Those with an indication for surgery
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Ankara Etlik City Hospital
Ankara, Yenimahalle, 06010
About this study
Official title: The Effectiveness of Cardiopulmonary Exercise in Children With Pectus Excavatum: A Single-Blind, Randomised Controlled Trial
The aim of this study is to investigate the effects of cardiopulmonary rehabilitation on respiratory function, exercise tolerance and posture in patients with pectus excavatum.
- Conditions
- Pectus Excavatum Deformity
- Being tested
- Cardiopulmonary exercises at hospital, Pulmonary and posture exercises at home
- Keywords
- pectus excavatum, cardiopulmonary exercises
- Medical subject headings
- Funnel Chest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cardiopulmonary exercises at hospitalOther
Patients will exercise using a bicycle ergometer. In addition, the same physiotherapist will demonstrate breathing and posture exercises for them to perform at home.
Pulmonary and posture exercises at homeOther
The physiotherapist will demonstrate the breathing and posture exercises to be performed at home.
| Study group | Role | What they receive |
|---|---|---|
| cardiopulmonary exercises group at hospital | Experimental | The working group will be provided with a personalised exercise plan by a physiotherapist specialising in that field at the cardiopulmonary rehabilitation unit, to be carried out twice a week for five weeks. Patients will work on a bicycle ergometer. In addition, the same physiotherapist will demonstrate breathing and posture exercises for patients to perform at home. Receives: Other: Cardiopulmonary exercises at hospital |
| pulmonary exercises group at home | Active comparator | The physiotherapist will only demonstrate the breathing and posture exercises that patients in the control group will perform at home. Receives: Other: Pulmonary and posture exercises at home |
What is being measured
The primary outcome is the main question the study is designed to answer.
Maximal inspiration and expiration pressure
Measured: first day of exercises program and 5th week of exercises program
Secondary outcomes (10)
6 minute walking test
Measured: first day of exercises program and 5th week of exercises program
New York Posture Scale
Measured: first day of exercises program and 5th week of exercises program
Measurement of chest expansion in centimetres using a tape measure
Measured: first day of exercises program and 5th week of exercises program
Assessment of symptoms (exercise intolerance, psychological impact, resting dyspnoea, chest pain, spinal pain, gastrointestinal symptoms, palpitations, dyspnoea) using a visual analogue scale
Measured: first day of exercises program and 5th week of exercises program
Cobb angle analysis using the Diers Formatrix 4D device (Wiesbaden, Germany)
Measured: first day of exercises program and 5th week of exercises program
Thoracic kyphosis angle
Measured: first day of exercises program and 5th week of exercises program
body lenght
Measured: first day of exercises program and 5th week of exercises program
Saggital balance angle using the Diers Formatrix 4D device (Wiesbaden, Germany)
Measured: first day of exercises program and 5th week of exercises program
Coronal balance angle using the Diers Formatrix 4D device (Wiesbaden, Germany)
Measured: first day of exercises program and 5th week of exercises program
pelvic obliquity angle using the Diers Formatrix 4D device (Wiesbaden, Germany)
Measured: first day of exercises program and 5th week of exercises program
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Dec 2025
- Study start9 Dec 2025
- Primary completion9 May 2026
- Study completion9 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pectus Excavatum DeformityStudies of the same condition, open and under way.
- More trials run by Ankara Etlik City HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ankara Etlik City Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Ayse Naz Kalem, Ankara Etlik City Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07300748
- Sponsor's protocol ID
- AEŞH-EK-2025-168
- Status last verified
- Feb 2026
- First submitted
- 13 Nov 2025
- Last updated
- 17 Jun 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Cardiopulmonary Exercise in Children With Pectus Excavatum: A Single-Blind, Randomised Controlled Trial
- ClinicalTrials.gov ID
- NCT07300748
- Acronym / sponsor ID
- AEŞH-EK-2025-168
- Conditions
- Pectus Excavatum Deformity
- Keywords
- pectus excavatum, cardiopulmonary exercises
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Ankara Etlik City HospitalOther government
- Study start
- 9 Dec 2025 (actual)
- Primary completion
- 9 May 2026 (actual)
- Study completion
- 9 May 2026 (actual)
- First posted
- 24 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the effects of cardiopulmonary rehabilitation on respiratory function, exercise tolerance and posture in patients with pectus excavatum.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| cardiopulmonary exercises group at hospital | Experimental | Other: Cardiopulmonary exercises at hospitalThe working group will be provided with a personalised exercise plan by a physiotherapist specialising in that field at the cardiopulmonary rehabilitation unit, to be carried out twice a week for five weeks. Patients will work on a bicycle ergometer. In addition, the same physiotherapist will demonstrate breathing and posture exercises for patients to perform at home. |
| pulmonary exercises group at home | Active comparator | Other: Pulmonary and posture exercises at homeThe physiotherapist will only demonstrate the breathing and posture exercises that patients in the control group will perform at home. |
Who may qualify
- Ages
- 5 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- Children aged 5-18 years with pectus excavatum deformity
- Children undergoing conservative treatment (vacuum orthosis, exercise)
- Patients whose families have signed a consent form agreeing to participate in the study
Key exclusion criteria (6 listed)
- Known cardiac disease
- Presence of an additional syndrome (Marfan syndrome, etc.)
- Cobb angle ≥10°
- Refusal to participate in the study
- Presence of mixed deformity (pectus arcuatum)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cardiopulmonary exercises at hospitalPatients will exercise using a bicycle ergometer. In addition, the same physiotherapist will demonstrate breathing and posture exercises for them to perform at home. | Other | cardiopulmonary exercises group at hospital |
| Pulmonary and posture exercises at homeThe physiotherapist will demonstrate the breathing and posture exercises to be performed at home. | Other | pulmonary exercises group at home |
Primary outcome
Maximal inspiration and expiration pressure
Time frame: first day of exercises program and 5th week of exercises program
10 secondary outcomes
6 minute walking test
Time frame: first day of exercises program and 5th week of exercises program
New York Posture Scale
Time frame: first day of exercises program and 5th week of exercises program
Measurement of chest expansion in centimetres using a tape measure
Time frame: first day of exercises program and 5th week of exercises program
Assessment of symptoms (exercise intolerance, psychological impact, resting dyspnoea, chest pain, spinal pain, gastrointestinal symptoms, palpitations, dyspnoea) using a visual analogue scale
Time frame: first day of exercises program and 5th week of exercises program
Cobb angle analysis using the Diers Formatrix 4D device (Wiesbaden, Germany)
Time frame: first day of exercises program and 5th week of exercises program
Thoracic kyphosis angle
Time frame: first day of exercises program and 5th week of exercises program
body lenght
Time frame: first day of exercises program and 5th week of exercises program
Saggital balance angle using the Diers Formatrix 4D device (Wiesbaden, Germany)
Time frame: first day of exercises program and 5th week of exercises program
Coronal balance angle using the Diers Formatrix 4D device (Wiesbaden, Germany)
Time frame: first day of exercises program and 5th week of exercises program
pelvic obliquity angle using the Diers Formatrix 4D device (Wiesbaden, Germany)
Time frame: first day of exercises program and 5th week of exercises program
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cardiopulmonary exercises at hospital and Pulmonary and posture exercises at home in people with Pectus Excavatum Deformity, run by Ankara Etlik City Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Maximal inspiration and expiration pressure (time frame: first day of exercises program and 5th week of exercises program). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Jun 2026.