Obstructive Sleep ApneaTOSANCT07302685
The Taiwan OSA Study
An observational study of Obstructive Sleep Apnea, run by China Medical University Hospital at 1 site in Taiwan.
Trial summary
We will prospectively recruit 7000 OSA patients referred to the sleep center or China Medical University Hospital between 2020 and 2027. Polysomnographic (PSG) study data, clinical features, and health data from the National Health Insurance Research Database will be linked. Read more about this study
- Who is it for?
- Ages 0 years and olderHealthy volunteers can take part
- Conditions the study is for
- Obstructive Sleep Apnea
- How many people
- 7,000 participants
- Where
- 1 siteTaiwan
- Study dates
- 10 Apr 2020to 28 Feb 2032
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 0 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Patients who are referred to China Medical University Hospital sleep center by physicians
Who may be able to join
- patients who are referred to China Medical University Hospital sleep center by physicians
Who cannot join
- -Individuals unable to complete at least 6 hours of PSG examination
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
China Medical University Hospital
Taichung, Taiwan, 404
Wan-Ju Cheng, Doctor, +1872 +886422052121, s871065@gmail.com
About this study
Official title: Clinical Features of Obstructive Sleep Apnea Patients With Different Phenotypes
We will prospectively recruit 7000 OSA patients referred to the sleep center or China Medical University Hospital between 2020 and 2027. Polysomnographic (PSG) study data, clinical features, and health data from the National Health Insurance Research Database will be linked. Endotypic traits will be determined by PSG study parameters. The associations between clinical features, endotypic traits, and health outcome will be examined. Some patients will be invited to receive lung function tests, blood serum tests, blood gas tests, and cognitive function tests.
- Conditions
- Obstructive Sleep Apnea
- Medical subject headings
- Sleep Apnea, Obstructive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Cohort Label | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Health outcome
Registered diagnosis in the National Health Insurance Database
Measured: Within 20 years from the date of the PSG examination
Secondary outcomes (4)
Sleep quality
Pittsburgh Sleep Quality Index (PSQI) ranges from 0 (better) to 21 (worse).
Measured: Baseline
Daytime sleepiness
Epworth Sleepiness Scale ranges from 0 (better) to 24 (worse)
Measured: Baseline
Sleep quality
Basic Nordic Sleep Questionnaire,a higher Basic Nordic Sleep Questionnaire score indicates worse outcomes
Measured: Baseline
Sleep quality
Munich Chronotype Questionnaire
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Dec 2025
- Study start10 Apr 2020
- Primary completion28 Feb 2032 (estimated)
- Study completion28 Feb 2032 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obstructive Sleep ApneaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 7,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- China Medical University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Wan-Ju Cheng, China Medical University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07302685
- Sponsor's protocol ID
- CMUH109-REC3-018
- Acronym
- TOSA
- Status last verified
- Nov 2025
- First submitted
- 25 Nov 2025
- Last updated
- 24 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical Features of Obstructive Sleep Apnea Patients With Different Phenotypes
- ClinicalTrials.gov ID
- NCT07302685
- Acronym / sponsor ID
- TOSA / CMUH109-REC3-018
- Conditions
- Obstructive Sleep Apnea
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 7,000 participants (estimated)
- Lead sponsor
- China Medical University HospitalUniversity, hospital or other
- Study start
- 10 Apr 2020 (actual)
- Primary completion
- 28 Feb 2032 (estimated)
- Study completion
- 28 Feb 2032 (estimated)
- First posted
- 24 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
We will prospectively recruit 7000 OSA patients referred to the sleep center or China Medical University Hospital between 2020 and 2027. Polysomnographic (PSG) study data, clinical features, and health data from the National Health Insurance Research Database will be linked. Endotypic traits will be determined by PSG study parameters. The associations between clinical features, endotypic traits, and health outcome will be examined. Some patients will be invited to receive lung function tests, blood serum tests, blood gas tests, and cognitive function tests.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Cohort Label | – | – |
Who may qualify
- Ages
- 0 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients who are referred to China Medical University Hospital sleep center by physicians
Key inclusion criteria (1 listed)
- patients who are referred to China Medical University Hospital sleep center by physicians
Key exclusion criteria (1 listed)
- -Individuals unable to complete at least 6 hours of PSG examination
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Health outcome
Time frame: Within 20 years from the date of the PSG examination
Registered diagnosis in the National Health Insurance Database
4 secondary outcomes
Sleep quality
Time frame: Baseline
Daytime sleepiness
Time frame: Baseline
Sleep quality
Time frame: Baseline
Sleep quality
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Dec 2025.
Related trials for Obstructive Sleep Apnea
Not yet recruitingPhase 2
Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs
Obesity & Overweight, Respiratory Depression
Not yet recruiting
Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions
Hypoxemia, Gastric Cancer (Diagnosis)
RecruitingObservational study
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Pediatric Obstructive Sleep Apnea
Enrolling by invitation
Myofunctional Therapy for Obstructive Sleep Apnea
Obstructive Sleep Apnea
Recruiting
Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep Apnea
Obstructive Sleep Apnea, Sleep Quality
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Obstructive Sleep Apnea, run by China Medical University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Wan-Ju Cheng, Doctor (+1872 +886422052121, s871065@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Health outcome (time frame: Within 20 years from the date of the PSG examination). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Dec 2025.