Adhesive CapsulitisNCT07310810
Mulligan Mobilization vs Shockwave Therapy in Adhesive Capsulitis
A study testing Shockwave, Mulligan mobilization and Conventional treatment in people with Adhesive Capsulitis, run by Cairo University at 1 site in Egypt.
Trial summary
To investigate and compare the effects of Mulligan mobilization versus shock wave therapy in patients with adhesive capsulitis on Pain intensity level, Range of motion, Functional disability level, Ultrasonographic changes (soft tissue thickness) and Hand grip strength. Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Adhesive Capsulitis
- What is being tested?
- Shockwave, Mulligan mobilization and Conventional treatment
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 1 May 2025to 1 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients referred from orthopedist and diagnosed as frozen shoulder The age of the participant will be from 40-60 (Agarwal S., et al.2016). Body mass index from 25- 30 kg/m2. having a painful stiff shoulder for at least 3 months having limited ROM of a shoulder joint (ROM losses of 25% or greater compared with the noninvolved shoulder in at least 2 of the following shoulder motions: glenohumeral flexion, abduction and lateral rotation.
- ability to complete Disabilities of the Arm, Shoulder and Hand questionnaires (DASH).
Who cannot join
- history of surgery on the particular shoulder Rheumatoid arthritis painful stiff shoulder after a severe trauma fracture of the shoulder complex rotator cuff rupture tendon calcification.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Mulligan Mobilization Versus Extracorporeal Shockwave Therapy on Ultrasonographic Changes in Patients With Adhesive Capsulitis
To investigate and compare the effects of Mulligan mobilization versus shock wave therapy in patients with adhesive capsulitis on Pain intensity level, Range of motion, Functional disability level, Ultrasonographic changes (soft tissue thickness) and Hand grip strength.
Read the detailed description
sixty patients of both genders according to sample size calculation, referred from orthopedist, diagnosed adhesive capsulitis patients. they screened according to inclusion and exclusion criteria. Their age between 40 and 60 years was randomly allocated to three treatment groups.
- Group A (study group) (n=20) will receive mulligan technique and conventional treatment.
- Group B (study group) (n=20) will receive extracorporeal shockwave therapy and conventional treatment.
- Group C (control group) (n=20) will receive conventional treatment only.
Inclusion criteria: patients that will be included in the study will be referred from orthopedic physician with:
- Patients referred from orthopedist and diagnosed as frozen shoulder
- The age of the participant will be from 40-60 (Agarwal S., et al.2016).
- Body mass index from 25- 30 kg/m2.
- having a painful stiff shoulder for at least 3 months
- having limited ROM of a shoulder joint (ROM losses of 25% or greater compared with the noninvolved shoulder in at least 2 of the following shoulder motions: glenohumeral flexion, abduction and lateral rotation.
- ability to complete Disabilities of the Arm, Shoulder and Hand questionnaires (DASH).
Exclusion criteria:
- history of surgery on the particular shoulder
- Rheumatoid arthritis
- painful stiff shoulder after a severe trauma
- fracture of the shoulder complex
- rotator cuff rupture
- tendon calcification.
- Conditions
- Adhesive Capsulitis
- Being tested
- Shockwave, Mulligan mobilization, Conventional treatment
- Keywords
- Adhesive capsulitis, Mulligan mobilization, EXTRACORPOREAL SHOCKWAVE THERAPY, ULTRASONOGRAPHIC CHANGES
- Medical subject headings
- Bursitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ShockwaveDevice
From sitting with shoulder abducted at 45 degree and elbow flexed and the forearm rested on flat surface, The patients in the intervention group B received shock wave therapy once a week for 4 weeks. The focus probe sets were used and, in each session, patients received ESWT from anterior and posterior directions (on the average 1200 shocks between 0.1 and 0.3 mJ/mm2) up to the maximum threshold of pain tolerance in the shoulder
Mulligan mobilizationOther
Also called Mobilization with movement
Mobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier
Conventional treatmentOther
Conventional treatment will be axillary ultrasound and laser ,low loading stretching exercise and home program exercises
| Study group | Role | What they receive |
|---|---|---|
| - Group A (study group) | Experimental | received mulligan technique and conventional treatment Receives: Other: Mulligan mobilization; Other: Conventional treatment |
| Group B (study group) | Experimental | received extracorporeal shockwave therapy and conventional treatment. Receives: Device: Shockwave; Other: Conventional treatment |
| Group C (control group) | Experimental | received conventional treatment only. Receives: Other: Conventional treatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain intensity level.
measured by Visual analog scale
Measured: 4 weeks
Range of motion.
measured by digital goniometer
Measured: 4 weeks
Functional disability level.
Determined by Disabilities of the arm, shoulder and hand questionnaire (DASH)
Measured: 4 weeks
Soft tissue thickness (Capsule thickness)
measured by musculoskeletal ultrasonography
Measured: 4 weeks
Hand grip strength
Measured by hand dynamometer
Measured: 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Dec 2025
- Study start1 May 2025
- Primary completion1 Jan 2026 (estimated)
- Study completion1 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Adhesive CapsulitisStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Ragab Gaber, Cairo University
- Investigators
- Mohamed R Gaber, Asst. lect., Principal investigator, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07310810
- Sponsor's protocol ID
- 012/005863
- Status last verified
- Dec 2025
- First submitted
- 16 Dec 2025
- Last updated
- 30 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mulligan Mobilization Versus Extracorporeal Shockwave Therapy on Ultrasonographic Changes in Patients With Adhesive Capsulitis
- ClinicalTrials.gov ID
- NCT07310810
- Acronym / sponsor ID
- 012/005863
- Conditions
- Adhesive Capsulitis
- Keywords
- Adhesive capsulitis, Mulligan mobilization, EXTRACORPOREAL SHOCKWAVE THERAPY, ULTRASONOGRAPHIC CHANGES
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 May 2025 (actual)
- Primary completion
- 1 Jan 2026 (estimated)
- Study completion
- 1 Feb 2026 (estimated)
- First posted
- 30 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To investigate and compare the effects of Mulligan mobilization versus shock wave therapy in patients with adhesive capsulitis on Pain intensity level, Range of motion, Functional disability level, Ultrasonographic changes (soft tissue thickness) and Hand grip strength.
Detailed description
sixty patients of both genders according to sample size calculation, referred from orthopedist, diagnosed adhesive capsulitis patients. they screened according to inclusion and exclusion criteria. Their age between 40 and 60 years was randomly allocated to three treatment groups.
- Group A (study group) (n=20) will receive mulligan technique and conventional treatment.
- Group B (study group) (n=20) will receive extracorporeal shockwave therapy and conventional treatment.
- Group C (control group) (n=20) will receive conventional treatment only.
Inclusion criteria: patients that will be included in the study will be referred from orthopedic physician with:
- Patients referred from orthopedist and diagnosed as frozen shoulder
- The age of the participant will be from 40-60 (Agarwal S., et al.2016).
- Body mass index from 25- 30 kg/m2.
- having a painful stiff shoulder for at least 3 months
- having limited ROM of a shoulder joint (ROM losses of 25% or greater compared with the noninvolved shoulder in at least 2 of the following shoulder motions: glenohumeral flexion, abduction and lateral rotation.
- ability to complete Disabilities of the Arm, Shoulder and Hand questionnaires (DASH).
Exclusion criteria:
- history of surgery on the particular shoulder
- Rheumatoid arthritis
- painful stiff shoulder after a severe trauma
- fracture of the shoulder complex
- rotator cuff rupture
- tendon calcification.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| - Group A (study group) | Experimental | Other: Mulligan mobilization, Other: Conventional treatmentreceived mulligan technique and conventional treatment |
| Group B (study group) | Experimental | Device: Shockwave, Other: Conventional treatmentreceived extracorporeal shockwave therapy and conventional treatment. |
| Group C (control group) | Experimental | Other: Conventional treatmentreceived conventional treatment only. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Patients referred from orthopedist and diagnosed as frozen shoulder The age of the participant will be from 40-60 (Agarwal S., et al.2016). Body mass index from 25- 30 kg/m2. having a painful stiff shoulder for at least 3 months having limited ROM of a shoulder joint (ROM losses of 25% or greater compared with the noninvolved shoulder in at least 2 of the following shoulder motions: glenohumeral flexion, abduction and lateral rotation.
- ability to complete Disabilities of the Arm, Shoulder and Hand questionnaires (DASH).
Key exclusion criteria (1 listed)
- history of surgery on the particular shoulder Rheumatoid arthritis painful stiff shoulder after a severe trauma fracture of the shoulder complex rotator cuff rupture tendon calcification.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ShockwaveFrom sitting with shoulder abducted at 45 degree and elbow flexed and the forearm rested on flat surface, The patients in the intervention group B received shock wave therapy once a week for 4 weeks. The focus probe sets were used and, in each session, patients received ESWT from anterior and posterior directions (on the average 1200 shocks between 0.1 and 0.3 mJ/mm2) up to the maximum threshold of pain tolerance in the shoulder | Device | Group B (study group) |
| Mulligan mobilizationAlso: Mobilization with movementMobilization with movement (MWM) is the concurrent application of sustained accessory mobilization applied by a therapist and an active physiological movement to end range applied by the patient. Passive end-of-range overpressure, or stretching, is then delivered without pain as a barrier | Other | - Group A (study group) |
| Conventional treatmentConventional treatment will be axillary ultrasound and laser ,low loading stretching exercise and home program exercises | Other | - Group A (study group), Group B (study group), Group C (control group) |
Primary outcome
Pain intensity level.
Time frame: 4 weeks
measured by Visual analog scale
Range of motion.
Time frame: 4 weeks
measured by digital goniometer
Functional disability level.
Time frame: 4 weeks
Determined by Disabilities of the arm, shoulder and hand questionnaire (DASH)
Soft tissue thickness (Capsule thickness)
Time frame: 4 weeks
measured by musculoskeletal ultrasonography
Hand grip strength
Time frame: 4 weeks
Measured by hand dynamometer
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Dec 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Mohamed R Gaber, Asst. lect. principal investigator
Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Shockwave, Mulligan mobilization and Conventional treatment in people with Adhesive Capsulitis, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 30 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain intensity level. (time frame: 4 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Dec 2025.