Chronic Kidney DiseasesVRENCT07316725
the Effect of Virtual Reality Exercise on Selected Electrolytes Levels in Intradialytic Patients
A study testing Virtual Reality Exercise in people with Chronic Kidney Diseases, run by Cairo University.
Trial summary
this study will be conducted to investigate the effect of Intra-Dialysis virtual reality exercise on selected electrolytes balance in patients with end stage renal disease. Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Chronic Kidney Diseases
- What is being tested?
- Virtual Reality Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- No sites listed yet
- Study dates
- 1 Jan 2026to 1 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients are diagnosed with end stage renal disease on regular dialysis.
- Their ages will be arranged from 20-40 years old.
- All patients are under medical control.
- Patients on regular dialysis more than 3 months.
Who cannot join
- Visual impairment.
- Severe cognitive impairment.
- Recent major surgery.
- Patients with sever musculoskeletal problems.
- Severe cardiovascular disease limiting exercise.
- Patients with Hemoglobin drop less than 9 g/dl
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
this study will be conducted to investigate the effect of Intra-Dialysis virtual reality exercise on selected electrolytes balance in patients with end stage renal disease.
Read the detailed description
Chronic Kidney Disease (CKD) is a progressive condition that often leads to end-stage renal disease, requiring dialysis. Patients undergoing hemodialysis frequently experience physical inactivity and electrolyte imbalances, which can adversely affect their health outcomes. Regular physical activity is crucial for maintaining muscle strength and physical function in CKD patients.Electrolytes play vital roles in various physiological functions, including muscle contraction, nerve transmission, and fluid balance. In end stage renal disease patients, imbalances can lead to serious complications, including: hyperkalemia, Hyponatremia, and hypocalcemia.VR has been employed in medicine to assist patients in recovering their motor and cognitive abilities. It has proven effective in enhancing physical functions such as posture, balance, and motor skills. When combined with physical exercise, VR has been shown to improve the functional abilities and quality of life of hemodialysis patients. For those with end stage renal disease patients, who experience discomfort during hemodialysis, VR offers a distraction that can reduce the perception of pain, fatigue, nausea, lightheadedness, and headaches, thereby facilitating smoother exercise continuity and enhancing overall adherence to rehabilitation activities. so this study will be conducted to assess the effect of Intra-Dialysis Virtual Reality Exercise on Selected Electrolytes Balance in Patients with End Stage Renal Disease
- Conditions
- Chronic Kidney Diseases
- Being tested
- Virtual Reality Exercise, standard care
- Keywords
- Virtual Reality Exercise, Selected Electrolytes Levels, Intradialytic Patients
- Medical subject headings
- Renal Insufficiency, Chronic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtual Reality ExerciseOther
the patients will receive 30 minutes virtual reality exercise; (5 minutes warm Up stretching exercise - 20 minutes cycling exercise -5 minutes cool down stretching exercise) plus standard care
standard careOther
the patients will receive standard care in the form of medical care
| Study group | Role | What they receive |
|---|---|---|
| Virtual Reality Exercise | Experimental | Twenty patients will receive virtual reality exercise during dialysis sessions three times per weeks for 3 months (30 minutes of guided VR exercise). Receives: Other: Virtual Reality Exercise; Other: standard care |
| standard care | Active comparator | Twenty patients will receive standard care during dialysis sessions three times per weeks for 3 months. Receives: Other: standard care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Serum Electrolyte Levels
Measurements the level of sodium, potassium, calcium and phosphorus by venous blood sample. the normal value for Sodium: 135-145 mEq/L
,Potassium: 3.5-5.0 mEq/L, Calcium: 8.5-10.2 mg/dL, and Phosphorus: 2.5-4.5 mg/dL
Measured: up to three months
Secondary outcomes (4)
blood pressure
A sphygmomanometer will be used to assess blood pressure with normal range 120/80
Measured: up to three months
oxygen saturation levels
A pulse oximeter will be used to assess oxygen saturation level. 95-100% considered normal for healthy individuals
Measured: up to three months
functional exercise capacity
6-Minute Walk Test will be used to assess functional exercises capacity
Measured: up to three months
exercise intensity
The Rated Perceived Exertion (RPE) Scale will be used to assess exercise intensity. it is a subjective 6-20 scale measuring exercise intensity, where 6 is no effort (rest) and 20 is maximum effort.
Measured: up to three months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Jan 2026
- Study start1 Jan 2026 (estimated)
- Primary completion1 Jun 2026 (estimated)
- Study completion1 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Kidney DiseasesStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- virtual reality and standard care
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, sarah mostafa mohamed, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07316725
- Sponsor's protocol ID
- P.T.REC/012/005982
- Acronym
- VRE
- Status last verified
- Dec 2025
- First submitted
- 19 Dec 2025
- Last updated
- 5 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- the Effect of Virtual Reality Exercise on Selected Electrolytes Levels in Intradialytic Patients
- ClinicalTrials.gov ID
- NCT07316725
- Acronym / sponsor ID
- VRE / P.T.REC/012/005982
- Conditions
- Chronic Kidney Diseases
- Keywords
- Virtual Reality Exercise, Selected Electrolytes Levels, Intradialytic Patients
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (estimated)
- Primary completion
- 1 Jun 2026 (estimated)
- Study completion
- 1 Jun 2026 (estimated)
- First posted
- 5 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study will be conducted to investigate the effect of Intra-Dialysis virtual reality exercise on selected electrolytes balance in patients with end stage renal disease.
Detailed description
Chronic Kidney Disease (CKD) is a progressive condition that often leads to end-stage renal disease, requiring dialysis. Patients undergoing hemodialysis frequently experience physical inactivity and electrolyte imbalances, which can adversely affect their health outcomes. Regular physical activity is crucial for maintaining muscle strength and physical function in CKD patients.Electrolytes play vital roles in various physiological functions, including muscle contraction, nerve transmission, and fluid balance. In end stage renal disease patients, imbalances can lead to serious complications, including: hyperkalemia, Hyponatremia, and hypocalcemia.VR has been employed in medicine to assist patients in recovering their motor and cognitive abilities. It has proven effective in enhancing physical functions such as posture, balance, and motor skills. When combined with physical exercise, VR has been shown to improve the functional abilities and quality of life of hemodialysis patients. For those with end stage renal disease patients, who experience discomfort during hemodialysis, VR offers a distraction that can reduce the perception of pain, fatigue, nausea, lightheadedness, and headaches, thereby facilitating smoother exercise continuity and enhancing overall adherence to rehabilitation activities. so this study will be conducted to assess the effect of Intra-Dialysis Virtual Reality Exercise on Selected Electrolytes Balance in Patients with End Stage Renal Disease
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- virtual reality and standard care
| Arm | Type | Receives |
|---|---|---|
| Virtual Reality Exercise | Experimental | Other: Virtual Reality Exercise, Other: standard careTwenty patients will receive virtual reality exercise during dialysis sessions three times per weeks for 3 months (30 minutes of guided VR exercise). |
| standard care | Active comparator | Other: standard careTwenty patients will receive standard care during dialysis sessions three times per weeks for 3 months. |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Patients are diagnosed with end stage renal disease on regular dialysis.
- Their ages will be arranged from 20-40 years old.
- All patients are under medical control.
- Patients on regular dialysis more than 3 months.
Key exclusion criteria (6 listed)
- Visual impairment.
- Severe cognitive impairment.
- Recent major surgery.
- Patients with sever musculoskeletal problems.
- Severe cardiovascular disease limiting exercise.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtual Reality Exercisethe patients will receive 30 minutes virtual reality exercise; (5 minutes warm Up stretching exercise - 20 minutes cycling exercise -5 minutes cool down stretching exercise) plus standard care | Other | Virtual Reality Exercise |
| standard carethe patients will receive standard care in the form of medical care | Other | Virtual Reality Exercise, standard care |
Primary outcome
Serum Electrolyte Levels
Time frame: up to three months
Measurements the level of sodium, potassium, calcium and phosphorus by venous blood sample. the normal value for Sodium: 135-145 mEq/L ,Potassium: 3.5-5.0 mEq/L, Calcium: 8.5-10.2 mg/dL, and Phosphorus: 2.5-4.5 mg/dL
4 secondary outcomes
blood pressure
Time frame: up to three months
oxygen saturation levels
Time frame: up to three months
functional exercise capacity
Time frame: up to three months
exercise intensity
Time frame: up to three months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Virtual Reality Exercise in people with Chronic Kidney Diseases, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 5 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact sarah mohamed, master (01149967455, sarahalsyed88@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Serum Electrolyte Levels (time frame: up to three months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Jan 2026; AzTrials last refreshed its copy on 2 Nov 2026.