Intestinal AnastomosisNCT07321743
Emergency Intestinal Anastmosis
A study testing emergency intestinal anastmosis surgery in people with Intestinal Anastomosis, run by Zagazig University at 1 site in Egypt.
Trial summary
The goal of this clinical trial is to compare the outcomes of emergency intestinal anastomosis after stapled and handsewn anastmosis. The main question it aims to answer are: Is stapled intestinal anastmosis is better than handsewn anastmosis in emergency laparotomy? Participants at surgical emergency unit: Had… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Intestinal Anastomosis
- What is being tested?
- emergency intestinal anastmosis surgery
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteEgypt
- Study dates
- 20 Dec 2024to 20 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- patients admitted to emergency surgery and needed intestinal anastmosis
Who cannot join
- patients below 18 years old
- immune-compromised patients e.g. corticosteroids therapy, autoimmue disease
Trial locations and contacts
1 site in 1 country.
Egypt1 site
faculty of medicine, Zagazig University
Zagazig, Sharqia Province, 44519
About this study
Official title: A Comparative Study Between Stapled and Handsewn Intestinal Anastmosis in Emergency Laparotomy
The goal of this clinical trial is to compare the outcomes of emergency intestinal anastomosis after stapled and handsewn anastmosis. The main question it aims to answer are:
Is stapled intestinal anastmosis is better than handsewn anastmosis in emergency laparotomy?
Participants at surgical emergency unit:
- Had intestinal anastmosis either by stapler or handsewn.
- kept in hospital for follow up and detection of complications like wound infection and leakage.
- Either discharged or managed according to the complications
- Outcomes were compared between the two groups
- Conditions
- Intestinal Anastomosis
- Being tested
- emergency intestinal anastmosis surgery
- Keywords
- stapler, handsewn, anastomotic leakage, intestinal obstruction
- Medical subject headings
- Anastomotic Leak, Intestinal Obstruction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
emergency intestinal anastmosis surgeryProcedure or surgery
cases with intestinal trauma, perforation or intestinal obstruction had emergency laparotomy and intestinal anastmosis was done
| Study group | Role | What they receive |
|---|---|---|
| stapled group | Active comparator | Not described Receives: Procedure: emergency intestinal anastmosis surgery |
| handsewn group | Active comparator | Not described Receives: Procedure: emergency intestinal anastmosis surgery |
What is being measured
The primary outcome is the main question the study is designed to answer.
intestinal leakage
intestinal leakage output calculated in ml by weighing dressing or calculating the drain output
Measured: from one day to two weeks after surgery
Secondary outcomes (4)
operation time
operation time in minutes was calculated
Measured: from incision time to closure (0 to 5 hours)
bleeding
bleeding amount was calculated in ml
Measured: from one hour to two days after surgery
hospital stay
hospital stay was recorded in days
Measured: from one day to one month after surgery
post-operative pain
pain was evaluated by the visual analogue scale from 1 to 10. score 1 means least painful, score 10 means very painful
Measured: from one to three days after after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Jan 2026
- Study start20 Dec 2024
- Primary completion20 Dec 2025
- Study completion20 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Intestinal AnastomosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zagazig University
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Reham Zakaria Mohamed Ahmed, Zagazig University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07321743
- Sponsor's protocol ID
- 942\31-Dec-2024
- Status last verified
- Dec 2025
- First submitted
- 22 Dec 2025
- Last updated
- 7 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Comparative Study Between Stapled and Handsewn Intestinal Anastmosis in Emergency Laparotomy
- ClinicalTrials.gov ID
- NCT07321743
- Acronym / sponsor ID
- 942\31-Dec-2024
- Conditions
- Intestinal Anastomosis
- Keywords
- stapler, handsewn, anastomotic leakage, intestinal obstruction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Zagazig UniversityOther government
- Study start
- 20 Dec 2024 (actual)
- Primary completion
- 20 Dec 2025 (actual)
- Study completion
- 20 Dec 2025 (actual)
- First posted
- 7 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to compare the outcomes of emergency intestinal anastomosis after stapled and handsewn anastmosis. The main question it aims to answer are:
Is stapled intestinal anastmosis is better than handsewn anastmosis in emergency laparotomy?
Participants at surgical emergency unit:
- Had intestinal anastmosis either by stapler or handsewn.
- kept in hospital for follow up and detection of complications like wound infection and leakage.
- Either discharged or managed according to the complications
- Outcomes were compared between the two groups
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| stapled group | Active comparator | Procedure: emergency intestinal anastmosis surgery |
| handsewn group | Active comparator | Procedure: emergency intestinal anastmosis surgery |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- patients admitted to emergency surgery and needed intestinal anastmosis
Key exclusion criteria (2 listed)
- patients below 18 years old
- immune-compromised patients e.g. corticosteroids therapy, autoimmue disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| emergency intestinal anastmosis surgerycases with intestinal trauma, perforation or intestinal obstruction had emergency laparotomy and intestinal anastmosis was done | Procedure or surgery | handsewn group, stapled group |
Primary outcome
intestinal leakage
Time frame: from one day to two weeks after surgery
intestinal leakage output calculated in ml by weighing dressing or calculating the drain output
4 secondary outcomes
operation time
Time frame: from incision time to closure (0 to 5 hours)
bleeding
Time frame: from one hour to two days after surgery
hospital stay
Time frame: from one day to one month after surgery
post-operative pain
Time frame: from one to three days after after surgery
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing emergency intestinal anastmosis surgery in people with Intestinal Anastomosis, run by Zagazig University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
intestinal leakage (time frame: from one day to two weeks after surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jan 2026.