Cervical RadiculopathyCawthorneNCT07323992
To Investigate the Effect of Modified Cawthorne-cooksey Exercises on Cervical Proprioception and Functional Outcomes in Patients With Cervical Radiculopathy. Fifty Four Patients With Cervical Radiculopathy From Both Sexes Will be Selected Randomly and Allocated Into Two Equal Groups.
A study testing Cawthorne-Cooksey exercises and Therapeutic Ultrasound in people with Cervical Radiculopathy, run by German International University at 1 site in Egypt.
Trial summary
To investigate the effect of cawthorne-cooksey exercises on cervical proprioception and functional outcomes in patients with cervical radiculopathy Read more about this study
- Who is it for?
- Ages 30 to 45 years
- Conditions the study is for
- Cervical Radiculopathy
- What is being tested?
- Cawthorne-Cooksey exercises and Therapeutic Ultrasound
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 54 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Sep 2025to 15 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Their ages range from 30 to 45 years.
- Both sexes
- With mild to moderate cervical disability according to the neck disability index.
- Unilateral cervical radiculopathy for more than 6 months.
- Cervical radiculopathy due to disc prolapse (C5-C6) (C6-C7) mild to moderate or disc prolapse according to magnetic resonance image(MRI).
- Complaining from vertigo at least for 3 months.
- Normal body mass index (18.5 - 24.99Kg/m2).
Who cannot join
- Any other musculoskeletal disorders of the spine or upper extremity
- Patients with any other Neurological deficits, psychiatric disease Cervical myelopathy, Cognitive problems, vertebral fractures and previous history of spine or cervical surgery.
- Clinical instability, recent trauma.
- Structural abnormalities of the spine, osteoporosis, and spasmodic torticollis.
- Inflammatory or other specific disorders of spine such as ankylosing spondylitis and rheumatoid arthritis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Modified Cawthorne-Cooksey Exercises on Cervical Proprioception and Functional Outcomes in Patients With Cervical Radiculopathy
To investigate the effect of cawthorne-cooksey exercises on cervical proprioception and functional outcomes in patients with cervical radiculopathy
Read the detailed description
Fifty four patients with cervical radiculopathy from both sexes will be selected randomly outpatient clinic and allocated into two equal groups. The Control Group will receive the selected physical therapy program only (electrotherapy, manual therapy, strengthening exercises), study Group will receive the Cawthorne-Cooksey exercises program and the selected physical therapy program. Basic assumptions
It will be assumed that:
- All the patients will follow the instructions and the rehabilitation program that are given to them.
- The motivation and cooperation are the same for all patients
- The patients will exert their maximum efforts during the study.
Null Hypothesis:
It will be hypothesized that:
- There will be no significant effect of Cawthorne-Cooksey exercises on proprioception in patients with cervical radiculopathy.
- There will be no significant effect of Cawthorne-Cooksey exercises on functional outcomes in patients with cervical radiculopathy.
- Conditions
- Cervical Radiculopathy
- Being tested
- Cawthorne-Cooksey exercises, Therapeutic Ultrasound
- Keywords
- Cervical radiculopathy, disc, cervical, radiculopathy, nerve, root, compression
- Medical subject headings
- Radiculopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cawthorne-Cooksey exercisesOther
Cawthorne-Cooksey exercises are one form of vestibular exercises under this training involving centers such as visual, proprioceptive, and vestibular activities.
Cawthorne-Cooksey exercises, originally developed for vestibular rehabilitation, focus on eye-head-body coordination and postural adaptation. When adapted for cervical use, they may enhance neuromuscular control, improve cervical joint position sense, and promote motor learning. These exercises are made to compensate for the affected vestibular signals (which cause poor balance and coordination) by retraining the eye and body musculatures.
Therapeutic UltrasoundOther
The application of ultrasound therapy with patient prone lying position paravertebral in posterior aspect of neck. The Treatment parameter ( 1 MHZ, FR 100HZ , duty factor 75% , power intensity 1.5w/cm2 , continuous mode , treatment time 5 min ).
| Study group | Role | What they receive |
|---|---|---|
| Cawthorne-Cooksey exercises | Experimental | Cawthorne-Cooksey exercises are one form of vestibular exercises under this training involving centers such as visual, proprioceptive, and vestibular activities. Cawthorne-Cooksey exercises, originally developed for vestibular rehabilitation, focus on eye-head-body coordination and postural adaptation. When adapted for cervical use, they may enhance neuromuscular control, improve cervical joint position sense, and promote motor learning. These exercises are made to compensate for the affected vestibular signals (which cause poor balance and coordination) by retraining the eye and body musculatures. Receives: Other: Cawthorne-Cooksey exercises; Other: Therapeutic Ultrasound |
| Therapeutic Ultrasound | Experimental | Therapeutic Ultrasound:
The application of ultrasound therapy with patient prone lying position paravertebral in posterior aspect of neck. The Treatment parameter ( 1 MHZ, FR 100HZ , duty factor 75% , power intensity 1.5w/cm2 , continuous mode , treatment time 5 min ). Receives: Other: Therapeutic Ultrasound |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cervical Proprioception
Measuring Neck Proprioception by cervical joint position error via overhead laser pointer :
- Laser pointer: will be fixed to the subject's head by a strap to determine the degree of error in the test .
- Target paper: typically, 40 cm in diameter that contains concentric circles in 1 cm increments, divided into 4 quadrants intersecting at zero .
- Chair: a stable chair with back support and positioned such that it will not move when the subject will move his/her head during the test.
- Colored stickers: will be used to determine the starting and the ending points of the laser.
- Ruler: to measure the distance between the start point and endpoint in each direction on the target paper.
Measured: From enrollment to the end of treatment at 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Jan 2026
- Study start15 Sep 2025
- Primary completion15 Dec 2025
- Study completion15 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervical RadiculopathyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 54 participants (actual)
Sponsor and investigators
- Lead sponsor
- German International University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Khairy Abdullah Hussein, German International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07323992
- Sponsor's protocol ID
- P.T.REC/012/006093
- Acronym
- Cawthorne
- Status last verified
- Jan 2026
- First submitted
- 24 Dec 2025
- Last updated
- 13 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Modified Cawthorne-Cooksey Exercises on Cervical Proprioception and Functional Outcomes in Patients With Cervical Radiculopathy
- ClinicalTrials.gov ID
- NCT07323992
- Acronym / sponsor ID
- Cawthorne / P.T.REC/012/006093
- Conditions
- Cervical Radiculopathy
- Keywords
- Cervical radiculopathy, disc, cervical, radiculopathy, nerve, root, compression
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 54 participants (actual)
- Lead sponsor
- German International UniversityUniversity, hospital or other
- Study start
- 15 Sep 2025 (actual)
- Primary completion
- 15 Dec 2025 (actual)
- Study completion
- 15 Dec 2025 (actual)
- First posted
- 7 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To investigate the effect of cawthorne-cooksey exercises on cervical proprioception and functional outcomes in patients with cervical radiculopathy
Detailed description
Fifty four patients with cervical radiculopathy from both sexes will be selected randomly outpatient clinic and allocated into two equal groups. The Control Group will receive the selected physical therapy program only (electrotherapy, manual therapy, strengthening exercises), study Group will receive the Cawthorne-Cooksey exercises program and the selected physical therapy program. Basic assumptions
It will be assumed that:
- All the patients will follow the instructions and the rehabilitation program that are given to them.
- The motivation and cooperation are the same for all patients
- The patients will exert their maximum efforts during the study.
Null Hypothesis:
It will be hypothesized that:
- There will be no significant effect of Cawthorne-Cooksey exercises on proprioception in patients with cervical radiculopathy.
- There will be no significant effect of Cawthorne-Cooksey exercises on functional outcomes in patients with cervical radiculopathy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Cawthorne-Cooksey exercises | Experimental | Other: Cawthorne-Cooksey exercises, Other: Therapeutic UltrasoundCawthorne-Cooksey exercises are one form of vestibular exercises under this training involving centers such as visual, proprioceptive, and vestibular activities. Cawthorne-Cooksey exercises, originally developed for vestibular rehabilitation, focus on eye-head-body coordination and postural adaptation. When adapted for cervical use, they may enhance neuromuscular control, improve cervical joint position sense, and promote motor learning. These exercises are made to compensate for the affected vestibular signals (which cause poor balance and coordination) by retraining the eye and body musculatures. |
| Therapeutic Ultrasound | Experimental | Other: Therapeutic UltrasoundTherapeutic Ultrasound: The application of ultrasound therapy with patient prone lying position paravertebral in posterior aspect of neck. The Treatment parameter ( 1 MHZ, FR 100HZ , duty factor 75% , power intensity 1.5w/cm2 , continuous mode , treatment time 5 min ). |
Who may qualify
- Ages
- 30 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Their ages range from 30 to 45 years.
- Both sexes
- With mild to moderate cervical disability according to the neck disability index.
- Unilateral cervical radiculopathy for more than 6 months.
- Cervical radiculopathy due to disc prolapse (C5-C6) (C6-C7) mild to moderate or disc prolapse according to magnetic resonance image(MRI).
Key exclusion criteria (5 listed)
- Any other musculoskeletal disorders of the spine or upper extremity
- Patients with any other Neurological deficits, psychiatric disease Cervical myelopathy, Cognitive problems, vertebral fractures and previous history of spine or cervical surgery.
- Clinical instability, recent trauma.
- Structural abnormalities of the spine, osteoporosis, and spasmodic torticollis.
- Inflammatory or other specific disorders of spine such as ankylosing spondylitis and rheumatoid arthritis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cawthorne-Cooksey exercisesCawthorne-Cooksey exercises are one form of vestibular exercises under this training involving centers such as visual, proprioceptive, and vestibular activities. Cawthorne-Cooksey exercises, originally developed for vestibular rehabilitation, focus on eye-head-body coordination and postural adaptation. When adapted for cervical use, they may enhance neuromuscular control, improve cervical joint position sense, and promote motor learning. These exercises are made to compensate for the affected vestibular signals (which cause poor balance and coordination) by retraining the eye and body musculatures. | Other | Cawthorne-Cooksey exercises |
| Therapeutic UltrasoundThe application of ultrasound therapy with patient prone lying position paravertebral in posterior aspect of neck. The Treatment parameter ( 1 MHZ, FR 100HZ , duty factor 75% , power intensity 1.5w/cm2 , continuous mode , treatment time 5 min ). | Other | Cawthorne-Cooksey exercises, Therapeutic Ultrasound |
Primary outcome
Cervical Proprioception
Time frame: From enrollment to the end of treatment at 8 weeks
Measuring Neck Proprioception by cervical joint position error via overhead laser pointer : 1. Laser pointer: will be fixed to the subject's head by a strap to determine the degree of error in the test . 2. Target paper: typically, 40 cm in diameter that contains concentric circles in 1 cm increments, divided into 4 quadrants intersecting at zero . 3. Chair: a stable chair with back support and positioned such that it will not move when the subject will move his/her head during the test. 4. Colored stickers: will be used to determine the starting and the ending points of the laser. 5. Ruler: to measure the distance between the start point and endpoint in each direction on the target paper.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Jan 2026.
Related trials for Cervical Radiculopathy
Recruiting
Ultrasound-Guided Electrical Dry Needling for Chronic Cervical Radiculopathy
Cervical Radiculopathy
Not yet recruitingObservational study
Correlation Between Forward Head Posture and Executive Functions in Cervical Radiculopathy
Cervical Radiculopathy, Forward Head Posture
Recruiting
Myo-Electrical and Nerve Root Function Response to Focused Extracorpeal Shock Wave in Cervical Radiculopathy
Cervical Radiculopathy
Not yet recruiting
Endoscopic Posterior Cervical Foraminotomy Versus Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy
Cervical Disc Herniation, Cervical Foraminal Stenosis
RecruitingObservational study
Cervical Spinal Cord Signal Abnormalities in Patients With Cervical Radicular Pain
Cervical Radiculopathy, Cervical Myelomalacia
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cawthorne-Cooksey exercises and Therapeutic Ultrasound in people with Cervical Radiculopathy, run by German International University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cervical Proprioception (time frame: From enrollment to the end of treatment at 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Jan 2026.