Chronic Low Back Pain (Non-specific, Uncomplicated)NCT07324538
Immediate Effects of Manual and Verbal Cueing During Movement Control Training in Chronic Non-Specific Low Back Pain
A study of Chronic Low Back Pain (Non-specific, Uncomplicated), run by National Yang Ming Chiao Tung University at 2 sites in Taiwan.
Trial summary
Chronic non-specific low back pain is commonly associated with impaired movement control. Movement control training is often used in rehabilitation, and different cueing methods may influence how patients perform and learn movements. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Chronic Low Back Pain (Non-specific, Uncomplicated)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 2 sitesTaiwan
- Study dates
- 8 Jul 2026to Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged 18 years or older
- Clinically diagnosed chronic non-specific low back pain with symptoms lasting longer than 12 weeks
- Able to understand and comply with the assessment and intervention procedures
Who cannot join
- History of surgery involving the lower back or lower extremities
- Presence of neurological symptoms, such as paresthesia or numbness
- Signs or symptoms of nerve root compression
- History of surgery within the past 3 months
- History of cancer
- Presence of major medical or psychiatric disorders
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- Presence of systemic inflammatory conditions
- Pregnancy
- Structural scoliosis
- Inability to walk or stand independently, or any condition deemed unsuitable for participation by the investigator
- Participation in any movement control exercise training within the past year
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan2 sites, 2 recruiting
- Recruiting
National Yang Ming Chiao Tung University
Taipei, Taiwan, 112
Wendy Tzyy-Jiuan Wang, PhD, 0928275082, tjwang@nycu.edu.tw
- Recruiting
Cheng Hsin General Hospital
Taipei, 112
About this study
Official title: A Randomized Controlled Trial Comparing the Immediate Effects of Manual and Verbal Cueing During Movement Control Training in Individuals With Chronic Non-Specific Low Back Pain
Chronic non-specific low back pain is commonly associated with impaired movement control. Movement control training is often used in rehabilitation, and different cueing methods may influence how patients perform and learn movements.
The purpose of this randomized controlled trial is to compare the immediate effects of manual cueing and verbal cueing during movement control training in individuals with chronic non-specific low back pain. Participants will be randomly assigned to receive either manual cueing or verbal cueing during a standardized movement training session.
The study will examine immediate changes in movement control performance, perceived difficulty, and related clinical outcomes following the intervention. The results of this study may help clinicians better understand how different cueing strategies influence movement performance in people with chronic non-specific low back pain.
- Being tested
- Movement Control Training With Manual Cueing, Movement Control Training With Verbal Cueing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Movement Control Training With Manual CueingBehavioural
Movement Control Training with Manual Cueing involves hands-on guidance provided by the therapist to enhance movement quality during standardized movement control training. Verbal instructions are used only to explain the movement sequence, while manuel guidance is primarily applied to facilitate movement quality.
Manual cueing is delivered according to the individual's needs and may include the following strategies:
- Gentle and evenly distributed manual pressure is applied to provide postural support and enhance awareness of appropriate points of support during movement.
- Manuel guidance is used to assist joint alignment when suboptimal alignment is observed during task performance, with attention to maintaining balanced muscle tone.
- Joint approximation techniques are applied as needed to provide compressive and stabilizing input to the joints, commonly used in neuromuscular facilitation approaches, to enhance joint stability and sensory feedback during movement.
Movement Control Training With Verbal CueingBehavioural
Movement control training with verbal cueing involves the use of spoken instructions and verbal feedback provided by the therapist to facilitate movement quality during standardized movement control training. Physical contact is not used during the intervention.
Verbal instructions are focused on key aspects of movement performance, including alignment and weight distribution, to support correct execution of the movement tasks. Examples of verbal cues include instructions such as maintaining the knee in a neutral position or directing attention to the distribution of load through the shoulder girdle during task performance.
| Study group | Role | What they receive |
|---|---|---|
| Manual Cueing Followed by Verbal Cueing | Experimental | Not described Receives: Behavioral: Movement Control Training With Manual Cueing; Behavioral: Movement Control Training With Verbal Cueing |
| Verbal Cueing Followed by Manual Cueing | Experimental | Not described Receives: Behavioral: Movement Control Training With Manual Cueing; Behavioral: Movement Control Training With Verbal Cueing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Movement Control Performance
Movement control performance assessed using the Nine-Item Movement Control Test Battery, which evaluates movement quality during standardized functional movement tasks. Each item is scored according to predefined error-based criteria, and item scores are summed to produce a total score ranging from 0 to 93, with higher scores indicating poorer movement control performance.
Measured: Immediately before and immediately after each intervention period
Pain Intensity
Pain intensity assessed using the Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable, with higher scores indicating greater pain intensity.
Measured: Immediately before and immediately after each intervention period
Secondary outcomes (2)
Perceived Difficulty Index
Perceived difficulty during movement performance assessed using the Perceived Difficulty Index (PDI). Participants rate the level of difficulty experienced during the movement tasks on a numeric rating scale ranging from 0 to 10, where 0 indicates no perceived difficulty and 10 indicates extreme difficulty, with higher scores indicating greater perceived difficulty.
Measured: Immediately after each intervention period
Perceived Learning Effect
Perceived learning following each intervention session, assessed by the therapist using a numeric rating scale from 0 (no learning) to 10 (complete mastery of key movement principles).
Measured: Immediately after each intervention period
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Jan 2026
- Study start8 Jul 2026
- Primary completionDec 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Low Back Pain (Non-specific, Uncomplicated)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Yang Ming Chiao Tung University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Wendy Tzyy-Jiuan Wang, National Yang Ming Chiao Tung University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07324538
- Sponsor's protocol ID
- NYCU114229AE-S2
- Status last verified
- Oct 2026
- First submitted
- 23 Dec 2025
- Last updated
- 14 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized Controlled Trial Comparing the Immediate Effects of Manual and Verbal Cueing During Movement Control Training in Individuals With Chronic Non-Specific Low Back Pain
- ClinicalTrials.gov ID
- NCT07324538
- Acronym / sponsor ID
- NYCU114229AE-S2
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- National Yang Ming Chiao Tung UniversityUniversity, hospital or other
- Study start
- 8 Jul 2026 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 7 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Chronic non-specific low back pain is commonly associated with impaired movement control. Movement control training is often used in rehabilitation, and different cueing methods may influence how patients perform and learn movements.
The purpose of this randomized controlled trial is to compare the immediate effects of manual cueing and verbal cueing during movement control training in individuals with chronic non-specific low back pain. Participants will be randomly assigned to receive either manual cueing or verbal cueing during a standardized movement training session.
The study will examine immediate changes in movement control performance, perceived difficulty, and related clinical outcomes following the intervention. The results of this study may help clinicians better understand how different cueing strategies influence movement performance in people with chronic non-specific low back pain.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Manual Cueing Followed by Verbal Cueing | Experimental | Behavioral: Movement Control Training With Manual Cueing, Behavioral: Movement Control Training With Verbal Cueing |
| Verbal Cueing Followed by Manual Cueing | Experimental | Behavioral: Movement Control Training With Manual Cueing, Behavioral: Movement Control Training With Verbal Cueing |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Adults aged 18 years or older
- Clinically diagnosed chronic non-specific low back pain with symptoms lasting longer than 12 weeks
- Able to understand and comply with the assessment and intervention procedures
Key exclusion criteria (11 listed)
- History of surgery involving the lower back or lower extremities
- Presence of neurological symptoms, such as paresthesia or numbness
- Signs or symptoms of nerve root compression
- History of surgery within the past 3 months
- History of cancer
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Movement Control Training With Manual CueingMovement Control Training with Manual Cueing involves hands-on guidance provided by the therapist to enhance movement quality during standardized movement control training. Verbal instructions are used only to explain the movement sequence, while manuel guidance is primarily applied to facilitate movement quality. Manual cueing is delivered according to the individual's needs and may include the following strategies: 1. Gentle and evenly distributed manual pressure is applied to provide postural support and enhance awareness of appropriate points of support during movement. 2. Manuel guidance is used to assist joint alignment when suboptimal alignment is observed during task performance, with attention to maintaining balanced muscle tone. 3. Joint approximation techniques are applied as needed to provide compressive and stabilizing input to the joints, commonly used in neuromuscular facilitation approaches, to enhance joint stability and sensory feedback during movement. | Behavioural | Manual Cueing Followed by Verbal Cueing, Verbal Cueing Followed by Manual Cueing |
| Movement Control Training With Verbal CueingMovement control training with verbal cueing involves the use of spoken instructions and verbal feedback provided by the therapist to facilitate movement quality during standardized movement control training. Physical contact is not used during the intervention. Verbal instructions are focused on key aspects of movement performance, including alignment and weight distribution, to support correct execution of the movement tasks. Examples of verbal cues include instructions such as maintaining the knee in a neutral position or directing attention to the distribution of load through the shoulder girdle during task performance. | Behavioural | Manual Cueing Followed by Verbal Cueing, Verbal Cueing Followed by Manual Cueing |
Primary outcome
Movement Control Performance
Time frame: Immediately before and immediately after each intervention period
Movement control performance assessed using the Nine-Item Movement Control Test Battery, which evaluates movement quality during standardized functional movement tasks. Each item is scored according to predefined error-based criteria, and item scores are summed to produce a total score ranging from 0 to 93, with higher scores indicating poorer movement control performance.
Pain Intensity
Time frame: Immediately before and immediately after each intervention period
Pain intensity assessed using the Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable, with higher scores indicating greater pain intensity.
2 secondary outcomes
Perceived Difficulty Index
Time frame: Immediately after each intervention period
Perceived Learning Effect
Time frame: Immediately after each intervention period
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study of Chronic Low Back Pain (Non-specific, Uncomplicated), run by National Yang Ming Chiao Tung University at 2 sites in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Angela Yu-Jung Chen (+886-2-28264400 ext. 3808, angelachen.be11@nycu.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Movement Control Performance (time frame: Immediately before and immediately after each intervention period). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.