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Cervical RadiculopathyNCT07330115

Combination of Kinesio Tape and Proprioceptive Neck Exercises on Proprioception in Patients With Cervical Radiculopathy

A study testing proprioceptive neck exercises and Kinesiotaping in people with Cervical Radiculopathy and Proprioception, run by Fadia Ahmed Fawzy.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
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Trial summary

This study is conducted to investigate: 1. The efficiency of combination of KT and proprioceptive exercises on neck proprioception in patients with CR. 2. The efficiency of combination of KT and proprioceptive exercises on neck pain, neck function and neuropathic pain in patients with CR. Read more about this study

Who is it for?
Ages 35 to 50 years
Conditions the study is for
Cervical Radiculopathy, Proprioception
What is being tested?
proprioceptive neck exercises and Kinesiotaping
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
No sites listed yet
Study dates
20 Jan 2026to 1 Apr 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 35 to 50 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Age from 35-50years (Rafiq et al. 2022).
  • BMI from 18 to 29.9 kg /m2 (Morsi et al., 2022.
  • Current continuous or intermittent pain that has persisted for more than 3 months (Persson et al., 1997, Purves et al., 1998).
  • Paresthesia or numbness along the course of the nerve (Young et al., 2009).
  • Positive response for the 4 Wainner RS et al., test's item cluster:
  • Ipsilateral cervical Spurling.
Show all 10Show fewer
  • Upper Limb Tension Tests (ULTTs).
  • Neck Distraction.
  • Spurling tests range (ROM) less than 60° (Wainner et al., 2003).
  • Unilateral affection in the upper limb.

Who cannot join

  • History of surgical procedures for pathologies giving rise to neck pain or CTS (Wainner et al., 2003).
  • Clinical signs or symptoms of medical "red flags" or serious pathology (infection, cancer, and cardiac involvement) (George et al., 2015).
  • Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis (Joghataei et al., 2004).
  • Systemic disease is known to cause generalized peripheral neuropathy as diabetes millitus (Wainner et al., 2003).
  • Upper Motor neuron disease such as stroke and amyotrophic lateral sclerosis (ALS) (Joghataei et al., 2004).
  • Complete loss of sensation along the involved nerve root (Moustafa \& Diab, 2014).
  • Primary report of bilateral radiating arm pain (Wainner et al., 2003)
  • Pregnant woman (Moustafa \& Diab, 2014).

Trial locations and contacts

No sites are listed yet. Contact the study team or a site near you to ask about taking part.

Fadia A Fawzy, Bachelor's contact

00201061054241

Fadiafawzy6@gmail.com

Enas F Youssef, Professor contact

00201127867507

Enas.fawzy@pt.cu.edu.eg

About this study

Official title: Combination of Kinesio Tape and Poprioceptive Neck Exercises on Proprioception in Patients With Cervical Radiculopathy

This study is conducted to investigate:

  1. The efficiency of combination of KT and proprioceptive exercises on neck proprioception in patients with CR.
  2. The efficiency of combination of KT and proprioceptive exercises on neck pain, neck function and neuropathic pain in patients with CR.
Read the detailed description

Cervical radiculopathy is a common neck disorder that reduces function, productivity, and quality of life. Cervical radiculopathy impacts cervical nerves roots, with the highest prevalence of C6 and C7 nerve roots. The incidence of cervical radiculopathy affects roughly 107.3 out of 100,000 males and 63.5 out of 100, 000 females. This incidence in the fifth decade of life increases up to 203 per 100 000. The etiology of cervical radiculopathy is commonly attributed to mechanical compression or chemical irritation of the cervical nerve roots. The most contributing factor is probably related to disc herniation. Other problems that decrease the intervertebral foramen include trauma, infection, and tumors .

Inflammation or impingement of these nerve roots trigger pain receptors located in soft tissues and joints of the cervical spine, resulting in sensory changes such as tingling and motor loss in dermatomal and myotomal distribution depending on affected nerve root. Patients often complain of combination of neck pain and radiating pain in the arm. The impairments in cervical proprioceptive inputs have been attributed to neck pain and altered input from cervical afferents, particularly muscle spindle, Muscle spindles are accepted as being the primary cervical receptors responsible for position sense and are coupled to supplementary afferent input from the cutaneous and joint receptors.

Conservative treatment approaches described to date have included pharmacology, advice to remain active, manual therapy, exercise, acupuncture, traction, collars, epidural injection in addition to kinesio tape (KT). Manual therapy can include muscle energy techniques, high velocity manipulation or low velocity mobilization of the cervical and/or thoracic spine, soft-tissue mobilization, and neural mobilization techniques.

Previously, in different musculoskeletal problems, KT combined with conventional rehabilitation has been shown to produce greater improvements in pain, range of motion, and functional outcomes compared to the rehabilitation program alone in cervical spondylosis and low back pain. It was reported that in comparison to sham application, 2 weeks of kinesio tape (KT) application practiced in addition to a home exercise program was effective on pain and tenderness in individuals with cervical myofascial pain. Additionally, KT was effective on cervical proprioception 24 hours after its application in chronic neck pain patients. KT is believed to stimulate cutaneous and muscle mechanoreceptors, which enhances sensorimotor control and proprioceptive feedback, thereby assisting in movement coordination and reducing discomfort in ankle proprioception and different musculoskeletal conditions.

To date, there is only one study that specifically investigated the effect of KT on patient with CR. KT taping method along with manual therapy treatment, cervical stabilization exercises was effective in treating patients with cervical radiculopathy.

Exercise therapy is effective in the management of CR, which can relieve pain and improve cervical function. Many exercises used in management of CR like stretching exercises for tighten muscles. Neural mobilization techniques (e.g., Upper Limb Tension Test 1 sliding and gliding) to restore neural dynamics and decrease radicular pain .

Proprioceptive training can lead to significant improvements in proprioceptive and motor function across a range of healthy and clinical populations. General neck-shoulder ROM and cervical proprioceptive exercises including eye-head coordination exercise can be effective in improving neck proprioceptive acuity, pain, and disability in chronic nonspecific neck pain patients.

A study was conducted to investigate the effect of proprioceptive training on patients with CR, including cervical position sense training, head-eye coordination exercises, and postural control exercises. The authors reported a significant improvement in cervical ROM and marked reduction in pain intensity (VAS) in the proprioceptive training group compared to conventional physical therapy group.

The effectiveness of deep cervical flexors strengthening exercises has demonstrated positive outcomes in terms of decrease in neck pain and disability, improvement in sitting posture, enhanced neuromuscular control of the cervical flexors in patients with chronic neck pain, and improved proprioceptive acuity of the neck, indicating that proprioception can be enhanced with specific exercise.

Strengthening, stabilization, and eye-head coordination exercises directed toward the deep cervical flexors, scapular stabilizers, and oculomotor-cervical control has been shown to enhance cervical spine stability and improve proprioceptive function in neck pain.

To the best of the author's knowledge, no previous study combined proprioceptive exercises and Kinesio tape in management of CR. Consequently, this study will be conducted to examine the effect of this combination on proprioceptive in patients with CR.

Being tested
proprioceptive neck exercises, Kinesiotaping
Medical subject headings
Radiculopathy

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • proprioceptive neck exercisesOther

    Proprioceptive craniocervical exercises The patient will sit on a swivel chair with a backrest in front of a wall at a distance of 90 cm. A laser pointer will be fixed to the highest point of the patient's head, so the laser light will be projected on a target hanging on the wall (Espí-López et al., 2020). Then active cervical movements will be performed.

  • KinesiotapingOther

    For kinesio tape application, a method of brachial plexus application will be chosen .

Study groups in NCT07330115
Study groupRoleWhat they receive
proprioceptive neck exercises groupActive comparatorProprioceptive neck exercises The patient will sit on a swivel chair with a backrest in front of a wall at a distance of 90 cm. A laser pointer will be fixed to the highest point of the patient's head, so the laser light will be projected on a target hanging on the wall . Then active cervical movements will be performed.
Receives: Other: proprioceptive neck exercises
KT groupActive comparatorGroup B will receive KT.
Receives: Other: Kinesiotaping
KT and proprioceptive neck exercisesActive comparatorGroup C will receive both (proprioceptive neck exercercises and KT)
Receives: Other: proprioceptive neck exercises; Other: Kinesiotaping

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Cervical proprioception

    The most common method used for assessment of cervical proprioception is Joint Position Error test, the active movement angle reproduction test, which requires the subject to relocate a neutral head position or a target head position selected by the investigator (Loudon et al., 1997; Hillier et al., 2015). In head position sense measurement studies, the variable measured is the difference between the reference point position entrenched initially (either a neutral or target position) and the position produced by the subject when attempting to match the target position , This difference is called JPE and has angular units of degrees (°) (Hillier et al., 2015). JPE test demonstrates good intra- and inter-rater reliability and acceptable validity for evaluating cervical proprioception (Revel et al., 1991; Kristjansson et al., 2003). JPE test will be measured by Laser Pointer Device.

    Measured: Baseline and 4 weeks

Secondary outcomes (3)
  1. Cervical pain

    The ANPRS is used to capture the patient's level of pain. It is an 11-point scale, ranging from 0 (no pain) to 10 (worst pain imaginable). The (NPRS) has been reported to be moderate (ICC value 0.63) in patients with CR (Cleland et al., 2006), and with acceptable reliability (ICC value 0.76) in patients with neck pain (Cleland et al., 2008).

    Measured: at baseline and after 4 weeks

  2. Function

    The neck disability index (NDI) is the most widely used and validated instrument to assess the impact of neck pain on patients' functional activities and to measure outcomes in clinical practice and research. It consists of 10 questions: pain intensity, personal care, lifting, reading, headaches, concentration, work, driving, sleepi ng, and recreation (Vernon \& Mior, 1991). The Arabic version of NDI is a condition-specific valid tool to assess the level of disabilities in patients with neck pain. The NDI-Ar is a reliable and valid questionnaire in neck pain patients with test-retest reliability; the ICC of the Arabic version was 0.96 (Shaheen et al., 2013).

    Measured: at baseline and after 4 weeks.

  3. Radicular pain

    The Upper Limb Tension Test 1 (ULTT1) will be used as both a screening tool for detecting radicular pain and as an outcome measure to evaluate changes in neural mobility and symptoms improvement throughout the intervention period.This test is commonly used in patients with cervical radiculopathy and has been shown to be both reliable and clinically relevant in identifying altered neural dynamics (Nee et al., 2012).

    Measured: at baseline and after 4 weeks.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted9 Jan 2026
  2. Study start20 Jan 2026 (estimated)
  3. Primary completion1 Mar 2026 (estimated)
  4. Study completion1 Apr 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Model description
Participants will be randomly assigned into three parallel groups. The first group will receive proprioceptive neck exercises only, the second group will receive kinesio taping only, and the third group will receive a combination of both interventions. All groups will receive their assigned intervention throughout the study period.
Masking
Double blind
Who is masked
Participant, Outcomes assessor
Enrolment
60 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07330115
Sponsor's protocol ID
KT and DCT on CR
Status last verified
Jan 2026
First submitted
17 Dec 2025
Last updated
12 Jan 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Ferlinc A, Fabiani E, Velnar T, Gradisnik L. The Importance and Role of Proprioception in the Elderly: a Short Review. Mater Sociomed. 2019 Sep;31(3):219-221. doi: 10.5455/msm.2019.31.219-221.

    PubMed 31762707
  • Espi-Lopez GV, Aguilar-Rodriguez M, Zarzoso M, Serra-Ano P, Martinez DE LA Fuente JM, Ingles M, Marques-Sule E. Efficacy of a proprioceptive exercise program in patients with nonspecific neck pain: a randomized controlled trial. Eur J Phys Rehabil Med. 2021 Jun;57(3):397-405. doi: 10.23736/S1973-9087.20.06302-9. Epub 2020 Oct 13.

    PubMed 33047944
  • Caridi JM, Pumberger M, Hughes AP. Cervical radiculopathy: a review. HSS J. 2011 Oct;7(3):265-72. doi: 10.1007/s11420-011-9218-z. Epub 2011 Sep 9.

    PubMed 23024624
  • Agyenkwa SK, Mustafaoglu R, Yeldan I. Therapeutic Effects of Kinesiology Taping Versus Self-Mobilization on Neck Pain, Proprioception, Muscle Activity, and Respiratory Muscle Strength Among Prolonged Electronic Device Users. A Randomized Controlled Trial. Physiother Res Int. 2025 Apr;30(2):e70061. doi: 10.1002/pri.70061.

    PubMed 40214192

Questions about this trial

What is this clinical trial studying?

A study testing proprioceptive neck exercises and Kinesiotaping in people with Cervical Radiculopathy and Proprioception, run by Fadia Ahmed Fawzy.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 10 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 12 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Fadia A Fawzy, Bachelor's (00201061054241, Fadiafawzy6@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Cervical proprioception (time frame: Baseline and 4 weeks). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07330115, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jan 2026.

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