Wound HealingNCT07330154
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
A study testing Application of NBF gel after soft tissue graft surgery in people with Wound Healing and Palatal Wound, run by King Abdullah University Hospital at 1 site in Jordan.
Trial summary
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Wound Healing, Palatal Wound, Donor Site Complication
- What is being tested?
- Application of NBF gel after soft tissue graft surgery
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 36 participants
- Where
- 1 siteJordan
- Study dates
- 29 Oct 2025to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients with gingival recession that is indicated for root coverage or need for phenotype modification.
- 18 years or older.
- absence of systemic disease
- Non-smoker
- No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months
Who cannot join
- Pregnant or lactating woman.
- patients with immune or systemic diseases.
- Patients with an allergy to any ingredient in the gel.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Rand Aldurra, MClinDent Perio contact
Jordan1 site, 1 recruiting
- Recruiting
Jordan University of Science and Technology, Faculty of Dentistry
Irbid, Irbid Governorate, 22110
Lana Bader, DClinDent Perio, +962791200956, lmbader4@just.edu.jo
Rand Aldurra, MClinDent Perio, raaldurrah23@den.just.edu.jo
About this study
Official title: The Effectiveness of Nano Bio Fusion Gel (NBF) on Early Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel: a Double Blinded Randomized Controlled Clinical Trial
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are:
- Does NBF gel enhance wound healing after graft harvesting from the palate?
- Does NBF gel reduce the number of inflammatory mediators after surgery?
- Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing.
Read more
Study steps include:
- Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks.
- Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30).
- Wound fluid samples will be collected on days (0, 1, 2, 4, 7).
- Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.
Read the detailed description
A sample size of 36 subjects, with treated 18 sites in each group should be sufficient to detect a mean difference of 1 mm of the wound area between groups. Efforts will be made to balance the number of men and women in each group (if possible).
The participants will be recruited from patients coming to dental teaching clinics at Jordan University of Science and Technology. The patients will be randomly assigned into 2 groups using computer generated randomization sequence:
Group 1: placebo gel Group 2: NBF gel
The study's purpose and procedures will be clearly communicated to all patient. Prior to examination and treatment, each participant must sign a consent form.
Patients who require a soft tissue surgery to cover gingival recession around teeth, to modify the phenotype where there is a thin gingival tissue, or to increase the width and thickness of soft tissue will be included in the study. The soft tissue graft should be obtained from the palatal donor site by free gingival graft or depithelized connective tissue graft, leaving an open wound in the palate (around 3×6 mm size) that is going to heal by secondary intesntion.
After the procedure, patients will be instructed to use the gel 4 times a day for 4 weeks by applying it to the wound and massaging the area. It will be provided in a small opaque tube. One tube should be used each day. The clinician and the patient will be blinded to the type of gel used. Another doctor or dental assistant will be responsible for dispencing the gel to the patient according to the randomization sequence and the code sheet.
Oral hygiene measures will be prohibited for the first 2 weeks in the surgical area only to not disturb the wound healing. Patients should follow their oral hygiene routine for the rest of the teeth. They will be instructed to use 0.2% chlorhexidine mouth wash twice a day for 2 weeks after surgery.
The study will last for one month for each patient. Each patient will be assessed immediately before and after the surgery and on days (0, 1, 2, 4, 7, 15, 21, 30). Clinical photographs will be taken at each time point.
Wound fluid samples (WF) will be collected at the incision area immediately after surgery and wound closure (day 0) and on days (1, 2, 4, 7). Main inflammotry mediators will be assessed.
Study steps:
- T0(intervention): Pt will sign the consent form. Sof tissue graft surgery will be performed and the graft will be obtained from the palate. The surgery is not performed by one periodontist, but the assessment and measurements are done by the same blinded examiner.
- T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery): The wound will be measured to record all the primary and secondary outcomes. The exception is made for the collection of wound fluid samples on days 15, 21 and 30. As the wound will be probably closed by then, samples will not be collected, unless there is delayed wound healing and the fluid can be drawn from the wound.
Clinical photos will be taken before surgery and anesthesia, immediately after surgery and the rest of time points.
- Being tested
- Application of NBF gel after soft tissue graft surgery, Application of placebo gel after soft tissue graft surgery
- Keywords
- NBF gel, wound healing, palatal donor site, soft tissue graft
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Application of NBF gel after soft tissue graft surgeryDrug
Also called phenotype modification, recession coverage, free gingival graft, connective tissue graft
After the surgery, patients will be instructed to apply the NBF gel to the donor site on the palate for four times daily for 4 weeks. If there is a vertical releasing incision in the recipient site, the gel will be applied along that incision too. The first application will be performed immediately after surgery by the investigator using a sterile cotton applicator.
Application of placebo gel after soft tissue graft surgeryOther
Also called phenotype modification, recession coverage, free gingival graft, connective tissue graft
After the surgery, patients will be instructed to apply the placebo gel to the donor site on the palate for four times daily for 4 weeks. If there is a vertical releasing incision in the recipient site, the gel will be applied along that incision too. The first application will be performed immediately after surgery by the investigator using a sterile cotton applicator.
| Study group | Role | What they receive |
|---|---|---|
| Nano bio-fusion gingival gel (NBF) | Experimental | The gel should be applied 4 times daily for 4 weeks. After drying the surgical site in the palate with a sterile gauze, a pea size of the gel material is applied to the wound using cotton applicator. If there is a vertical relasing incision in the recipient site, the gel will be applied using the same technique. Receives: Drug: Application of NBF gel after soft tissue graft surgery |
| placebo gel | Placebo comparator | The gel should be applied 4 times daily for 4 weeks. After drying the surgical site in the palate with a sterile gauze, a pea size of the gel material is applied to the wound using cotton applicator. If there is a vertical relasing incision in the recipient site, the gel will be applied using the same technique. Receives: Other: Application of placebo gel after soft tissue graft surgery |
What is being measured
The primary outcome is the main question the study is designed to answer.
Wound area
The wound area of the palatal donor site will have a rectangular shape, and it will be measured in mm according to the following equation:
Area = length × width UNC15 periodontal probe will be used to do the measurements at the greatest dimension horizontally and vertically. The site will be left to heal by secondary intension.
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Secondary outcomes (7)
Early wound healing index (EWHI)
the amount of fibrin at the wound margin will be assessed using early wound healing index (EWHI). The index was used to assess healing after papilla preservation flap. It will be modified to use at the vertical releasing incision of the recipient site according to the following criteria:
- complete flap closure-no fibrin line at the incision line
- complete flap closure-fine fibrin line at the incision line
- complete flap closure-fibrin clot at the incision line
- incomplete flap closure-partial tissue necrosis at the incision line
- incomplete flap closure-complete tissue necrosis at the at the incision line
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Present or abscent (Yes/no):
- Pus discharge
- Bleeding on palpation
- Tenderness on palpation
- Presence of granulation tissue
- Scar (yes/no……if yes, wider or lesser than 2 mm, contour: regular or irregular)
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Erythema, redness + edema, swelling
mild <50% of the wound area, moderate 50%, severe >50%.
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Epithelization and exposure of CT
partial or complete epithelization
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Incision margins
measured for the vertical incsion on the recipient site if present. It will be recorded as: merged, in contact or in distance.
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Patient reported outcome measure (PROM)
Pain intensity: will be recorded on a visual analogue scale from 1-10. The higher the number the more the pain.
- Duration: min, hour, whole day
- Nature: continuous or intermittent - Consumption of Analgesics: Patients will be instructed to use 2 tabs of paracetamol 500 mg in case they feel pain. They should not use any other type of analgesics as it might affect the healing and inflammation. They will be requested to record the number of tablets and the times they were taken
Measured: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
cytokine measurement using ELISA test
Wound fluid samples (WF) will be collected from the palatal donor site and at the vertical incision using sterile paper points. Levels of cytokines (IL-1β, TNF-α, IL-6, IL-10) will be determined with Enzyme-Linked immunosorbent Assay test (ELISA) following the manufacturer's instructions.
Measured: Immediately after surgery and wound closure (day 0) and on days (1, 2, 4, 7). They will not be collected at days 15, 21, and 30 as the wound should be closed by then, unless there is delayed wound healing and the fluid can be collected from the wound.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jan 2026
- Study start29 Oct 2025
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Wound HealingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The study will recriute patients require soft tissue graft surgery where the graft is harvested from the palate by free gingival graft or depithelized connective tissue graft, leaving an open wound in the palate (around 3×6 mm size) that is going to heal by secondary intesntion. They will be randomly assigned into 2 groups using computer generated randomization sequence: Group 1: placebo gel Group 2: NBF gel
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 36 participants (estimated)
Sponsor and investigators
- Lead sponsor
- King Abdullah University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Jordan University of Science and Technology
- Responsible party
- Principal investigator, Lana Bader, King Abdullah University Hospital
- Investigators
- Lana Bader, DClinDent Perio, Study director, Jordan University of Science and TechnologyRand Aldurra, MClinDent Perio, Principal investigator, Jordan University of Science and Technology
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07330154
- Sponsor's protocol ID
- 440-2025
- Other IDs
- 2/185/2025
- Status last verified
- Jan 2026
- First submitted
- 27 Dec 2025
- Last updated
- 23 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual participant data for wound size, early wound healing index, and patient-reported outcomes will be shared. Data will be stripped of all identifiers to protect participants privacy.
Study at a glance
From the registry record, last updated by the sponsor on 23 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Nano Bio Fusion Gel (NBF) on Early Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel: a Double Blinded Randomized Controlled Clinical Trial
- ClinicalTrials.gov ID
- NCT07330154
- Acronym / sponsor ID
- 440-2025
- Keywords
- NBF gel, wound healing, palatal donor site, soft tissue graft
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 36 participants (estimated)
- Lead sponsor
- King Abdullah University HospitalUniversity, hospital or other
- Collaborators
- Jordan University of Science and Technology
- Study start
- 29 Oct 2025 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 9 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are:
- Does NBF gel enhance wound healing after graft harvesting from the palate?
- Does NBF gel reduce the number of inflammatory mediators after surgery?
- Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing.
Study steps include:
- Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks.
- Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30).
- Wound fluid samples will be collected on days (0, 1, 2, 4, 7).
- Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.
Detailed description
A sample size of 36 subjects, with treated 18 sites in each group should be sufficient to detect a mean difference of 1 mm of the wound area between groups. Efforts will be made to balance the number of men and women in each group (if possible).
The participants will be recruited from patients coming to dental teaching clinics at Jordan University of Science and Technology. The patients will be randomly assigned into 2 groups using computer generated randomization sequence:
Group 1: placebo gel Group 2: NBF gel
The study's purpose and procedures will be clearly communicated to all patient. Prior to examination and treatment, each participant must sign a consent form.
Patients who require a soft tissue surgery to cover gingival recession around teeth, to modify the phenotype where there is a thin gingival tissue, or to increase the width and thickness of soft tissue will be included in the study. The soft tissue graft should be obtained from the palatal donor site by free gingival graft or depithelized connective tissue graft, leaving an open wound in the palate (around 3×6 mm size) that is going to heal by secondary intesntion.
After the procedure, patients will be instructed to use the gel 4 times a day for 4 weeks by applying it to the wound and massaging the area. It will be provided in a small opaque tube. One tube should be used each day. The clinician and the patient will be blinded to the type of gel used. Another doctor or dental assistant will be responsible for dispencing the gel to the patient according to the randomization sequence and the code sheet.
Oral hygiene measures will be prohibited for the first 2 weeks in the surgical area only to not disturb the wound healing. Patients should follow their oral hygiene routine for the rest of the teeth. They will be instructed to use 0.2% chlorhexidine mouth wash twice a day for 2 weeks after surgery.
The study will last for one month for each patient. Each patient will be assessed immediately before and after the surgery and on days (0, 1, 2, 4, 7, 15, 21, 30). Clinical photographs will be taken at each time point.
Wound fluid samples (WF) will be collected at the incision area immediately after surgery and wound closure (day 0) and on days (1, 2, 4, 7). Main inflammotry mediators will be assessed.
Study steps:
- T0(intervention): Pt will sign the consent form. Sof tissue graft surgery will be performed and the graft will be obtained from the palate. The surgery is not performed by one periodontist, but the assessment and measurements are done by the same blinded examiner.
- T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery): The wound will be measured to record all the primary and secondary outcomes. The exception is made for the collection of wound fluid samples on days 15, 21 and 30. As the wound will be probably closed by then, samples will not be collected, unless there is delayed wound healing and the fluid can be drawn from the wound.
Clinical photos will be taken before surgery and anesthesia, immediately after surgery and the rest of time points.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- The study will recriute patients require soft tissue graft surgery where the graft is harvested from the palate by free gingival graft or depithelized connective tissue graft, leaving an open wound in the palate (around 3×6 mm size) that is going to heal by secondary intesntion. They will be randomly assigned into 2 groups using computer generated randomization sequence: Group 1: placebo gel Group 2: NBF gel
| Arm | Type | Receives |
|---|---|---|
| Nano bio-fusion gingival gel (NBF) | Experimental | Drug: Application of NBF gel after soft tissue graft surgeryThe gel should be applied 4 times daily for 4 weeks. After drying the surgical site in the palate with a sterile gauze, a pea size of the gel material is applied to the wound using cotton applicator. If there is a vertical relasing incision in the recipient site, the gel will be applied using the same technique. |
| placebo gel | Placebo comparator | Other: Application of placebo gel after soft tissue graft surgeryThe gel should be applied 4 times daily for 4 weeks. After drying the surgical site in the palate with a sterile gauze, a pea size of the gel material is applied to the wound using cotton applicator. If there is a vertical relasing incision in the recipient site, the gel will be applied using the same technique. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Patients with gingival recession that is indicated for root coverage or need for phenotype modification.
- 18 years or older.
- absence of systemic disease
- Non-smoker
- No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months
Key exclusion criteria (3 listed)
- Pregnant or lactating woman.
- patients with immune or systemic diseases.
- Patients with an allergy to any ingredient in the gel.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Application of NBF gel after soft tissue graft surgeryAlso: phenotype modification, recession coverage, free gingival graft, connective tissue graftAfter the surgery, patients will be instructed to apply the NBF gel to the donor site on the palate for four times daily for 4 weeks. If there is a vertical releasing incision in the recipient site, the gel will be applied along that incision too. The first application will be performed immediately after surgery by the investigator using a sterile cotton applicator. | Drug | Nano bio-fusion gingival gel (NBF) |
| Application of placebo gel after soft tissue graft surgeryAlso: phenotype modification, recession coverage, free gingival graft, connective tissue graftAfter the surgery, patients will be instructed to apply the placebo gel to the donor site on the palate for four times daily for 4 weeks. If there is a vertical releasing incision in the recipient site, the gel will be applied along that incision too. The first application will be performed immediately after surgery by the investigator using a sterile cotton applicator. | Other | placebo gel |
Primary outcome
Wound area
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
The wound area of the palatal donor site will have a rectangular shape, and it will be measured in mm according to the following equation: Area = length × width UNC15 periodontal probe will be used to do the measurements at the greatest dimension horizontally and vertically. The site will be left to heal by secondary intension.
7 secondary outcomes
Early wound healing index (EWHI)
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Present or abscent (Yes/no):
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Erythema, redness + edema, swelling
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Epithelization and exposure of CT
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Incision margins
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
Patient reported outcome measure (PROM)
Time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)
cytokine measurement using ELISA test
Time frame: Immediately after surgery and wound closure (day 0) and on days (1, 2, 4, 7). They will not be collected at days 15, 21, and 30 as the wound should be closed by then, unless there is delayed wound healing and the fluid can be collected from the wound.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jan 2026.
- Individual participant dataSharing planned: Yes. Individual participant data for wound size, early wound healing index, and patient-reported outcomes will be shared. Data will be stripped of all identifiers to protect participants privacy.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Rand Aldurra, MClinDent Perio contact
Lana Bader, DClinDent Perio study director
Jordan University of Science and Technology
Rand Aldurra, MClinDent Perio principal investigator
Jordan University of Science and Technology
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Application of NBF gel after soft tissue graft surgery in people with Wound Healing and Palatal Wound, run by King Abdullah University Hospital at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Lana Bader, DClinDent Perio (+962791200956, lmbader4@just.edu.jo), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Wound area (time frame: On each follow up visit: T1 (24 hours after the surgery), T2 (2 days after the surgery), T3 (4 days after the surgery), T4 (7 days after the surgery), T5 (15 days after the surgery), T6 (21 days after the surgery), T7 (30 days after the surgery)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jan 2026.