Palliative CareNCT07339293
The Effect of Constipation Insoles on the Management of Constipation
A study testing constipation insole and Walk in people with Palliative Care and Constipation, run by Istanbul Aydın University at 1 site in Turkey (Türkiye).
Trial summary
Constipation is a common symptom among patients receiving palliative care and significantly affects their quality of life. Effective management of constipation requires both pharmacological and non-pharmacological approaches. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Palliative Care, Constipation
- What is being tested?
- constipation insole and Walk
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 139 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 10 Jan 2024to 30 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients who volunteer to participate in the study and are over 18 years of age,
- Patients without any cognitive, mental, or verbal communication impairments,
- Patients receiving palliative care,
- Patients with constipation,
- Patients with fewer than 3 bowel movements per week and/or at least one of the following constipation problems (straining during bowel movements, hard stools, feeling of incomplete emptying, gas/bloating, pressure/feeling of needing to defecate in the rectum).
Who cannot join
- Individuals with peripheral neuropathy,
- impaired foot skin integrity,
- flat feet or any foot deformity,
- and those using complementary treatments such as abdominal massage, acupressure, or acupuncture to relieve constipation were excluded from the study.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Constipation Insoles
Constipation is a common symptom among patients receiving palliative care and significantly affects their quality of life. Effective management of constipation requires both pharmacological and non-pharmacological approaches. Reflexology has been increasingly used as a complementary method for constipation management; however, factors such as the need for a trained reflexology specialist, time limitations, and financial constraints may limit patients' access to this intervention. To overcome these barriers, a constipation insole based on reflexology principles has been developed, which can be easily used by patients either at home or in clinical settings.
This study was designed as a randomized controlled experimental trial to evaluate the effectiveness of a constipation insole in the management of constipation in patients receiving palliative care. During the first week of the study, no intervention was applied in order to assess participants' baseline bowel habits. Starting from the second week, patients in the experimental group were instructed to walk with the constipation insole for 20 minutes per day for a total of four weeks. Patients in the control group were instructed to walk for 20 minutes per day for the same duration, without using the insole.
Read more
At baseline, data were collected using the Patient Identification Form and the General Comfort Scale. Throughout the study period, bowel function and constipation-related outcomes were monitored using standardized measurement tools. The Constipation Assessment Scale was planned to be administered every three days, the Constipation Severity Scale daily, and the Bristol Stool Consistency Scale at each defecation. The General Comfort Scale was planned to be re-administered on the 28th day of the intervention period.
The findings obtained from this study are expected to provide evidence regarding the potential role of constipation insoles as a complementary intervention in constipation management for patients in palliative care.
- Conditions
- Palliative Care, Constipation
- Being tested
- constipation insole, Walk
- Keywords
- constipation, palliative care, reflexology, nursing, comfort
- Medical subject headings
- Constipation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
constipation insoleBehavioural
Patients in the experimental group were instructed to walk with the constipation insole for 20 minutes a day for four weeks, starting from the second week
WalkBehavioural
Patients in the control group were only instructed to walk for 20 minutes a day for four weeks
| Study group | Role | What they receive |
|---|---|---|
| Experimental Group | Experimental | Patients in the experimental group were instructed to walk with the constipation insole for 20 minutes a day for four weeks, starting from the second week Receives: Behavioral: constipation insole; Behavioral: Walk |
| Control Group | Other | Patients in the control group were only instructed to walk for 20 minutes a day for four weeks. Receives: Behavioral: Walk |
What is being measured
The primary outcome is the main question the study is designed to answer.
Constipation Severity Scale
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Measured: First week
Constipation Severity Scale
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Measured: second week
Constipation Severity Scale
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Measured: third week
Constipation Severity Scale
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Measured: fifth week
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: Baseline
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: third day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: sixth day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: ninth day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: twelfth day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: fifteenth day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: eighteenth day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: twenty-first day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: twenty-fourth day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: twenty-seventh day
Constipation Assessment Scale
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Measured: thirtieth day
Overall Comfort Scale
It is a scale developed to assess an individual's need for comfort. In the evaluation of the scale, negatively worded items are reverse-coded and summed together with the positively worded items. The highest possible total score on the scale is 192, while the lowest possible total score is 48. The total score obtained is divided by the number of items on the scale to calculate the mean score, which is expressed on a scale ranging from 1 to 4. A score of 1 indicates low comfort, whereas a score of 4 indicates high comfort.
Measured: Baseline
Overall Comfort Scale
It is a scale developed to assess an individual's need for comfort. In the evaluation of the scale, negatively worded items are reverse-coded and summed together with the positively worded items. The highest possible total score on the scale is 192, while the lowest possible total score is 48. The total score obtained is divided by the number of items on the scale to calculate the mean score, which is expressed on a scale ranging from 1 to 4. A score of 1 indicates low comfort, whereas a score of 4 indicates high comfort.
Measured: thirty-fifth day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jan 2026
- Study start10 Jan 2024
- Primary completion30 Nov 2024
- Study completion30 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Palliative CareStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 139 participants (actual)
Sponsor and investigators
- Lead sponsor
- Istanbul Aydın University
- Sponsor type
- University, hospital or other
- Collaborators
- The Scientific and Technological Research Council of Turkey
- Responsible party
- Principal investigator, DİLEK YILDIRIM, Istanbul Aydın University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07339293
- Sponsor's protocol ID
- Constipation Insoles
- Status last verified
- Jan 2026
- First submitted
- 4 Jan 2026
- Last updated
- 14 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Patients have not given permission to share their data in this area.
Publications
References Akyüz Özdemir, F., Can, G. 2024. "The Effect of Reflexology Socks in the Management of Opioid-Induced Constipation: A Randomized Controlled Trial", Cancer Nursing, 10-1097. Anjoman, A. Z., Mirghafourvand, M., Hughes, C., Havizari, S. 2021. "Effect of Foot Reflexology on Constipation: A Systematic Review and Meta-Analysis", [Dergi adı belirtilmemiş]. Arıkan Dirimen, G. 2016. "Palyatif Bakım Tanımı ve Felsefesi", Klinik Tıp Aile Hekimliği, 8(3), 1-5. Ayık Bıçak, D., Can, G. 2020. "Palyatif Bakım Hastalarında Konstipasyonun Yönetimi ve Akupresürün Etkinliği", Sağlık Akademisyenleri Dergisi, 7(2), 141-148. Barichella, M. et al. 2016. "Probiotics and Prebiotic Fiber for Constipation Associated with Parkinson Disease", Neurology, 87(12), 1274-1280. Bassotti, G., Battaglia, E. 2023. "Considerations for laxatives in terms of their interactions with other drugs", Expert Opinion on Drug Metabolism & Toxicology, 19(3), 121-123. Bayan, K. 2017. "Konstipasyona Güncel Yaklaşım", Klinik Tıp Bilimleri Dergisi, 5(2). Bharucha, A. E., Lacy, B. E. 2020. "Mechanisms, Evaluation, and Management of Chronic Constipation", Gastroenterology, 158(5), 1232-1249.e3. Camilleri, M. et al. 2017. "Chronic Constipation", Nature Reviews Disease Primers, 3, 1-19. Canbulat Şahiner, N., Demirgoz Bal, M. 2017. "A Randomized Controlled Trial Examining the Effects of Reflexology on Children With Functional Constipation", Gastroenterology Nursing, 40(5), 393-400. Candy, B. et al. 2015. "Laxatives for the Management of Constipation in People Receiving Palliative Care", Cochrane Database of Systematic Reviews, 5. Cevik, K. 2013. "Complementary and Alternative Therapy in Nursing: Reflexology", Ege Hemşirelik Fakültesi Dergisi, 29(2), 71-82. Cevik, K., Zaybak, A. 2018. "The Effect of Reflexology on Constipation in the Elderly", International Journal of Caring Science, 11(1), 309-318. Clark, K., Currow, D. C. 2013. "Constipation in Palliative Care: What Do We Use as Definitions and Outco
Study at a glance
From the registry record, last updated by the sponsor on 14 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Constipation Insoles
- ClinicalTrials.gov ID
- NCT07339293
- Acronym / sponsor ID
- Constipation Insoles
- Conditions
- Palliative Care, Constipation
- Keywords
- constipation, palliative care, reflexology, nursing, comfort
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 139 participants (actual)
- Lead sponsor
- Istanbul Aydın UniversityUniversity, hospital or other
- Collaborators
- The Scientific and Technological Research Council of Turkey
- Study start
- 10 Jan 2024 (actual)
- Primary completion
- 30 Nov 2024 (actual)
- Study completion
- 30 Dec 2024 (actual)
- First posted
- 14 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Constipation is a common symptom among patients receiving palliative care and significantly affects their quality of life. Effective management of constipation requires both pharmacological and non-pharmacological approaches. Reflexology has been increasingly used as a complementary method for constipation management; however, factors such as the need for a trained reflexology specialist, time limitations, and financial constraints may limit patients' access to this intervention. To overcome these barriers, a constipation insole based on reflexology principles has been developed, which can be easily used by patients either at home or in clinical settings.
This study was designed as a randomized controlled experimental trial to evaluate the effectiveness of a constipation insole in the management of constipation in patients receiving palliative care. During the first week of the study, no intervention was applied in order to assess participants' baseline bowel habits. Starting from the second week, patients in the experimental group were instructed to walk with the constipation insole for 20 minutes per day for a total of four weeks. Patients in the control group were instructed to walk for 20 minutes per day for the same duration, without using the insole.
At baseline, data were collected using the Patient Identification Form and the General Comfort Scale. Throughout the study period, bowel function and constipation-related outcomes were monitored using standardized measurement tools. The Constipation Assessment Scale was planned to be administered every three days, the Constipation Severity Scale daily, and the Bristol Stool Consistency Scale at each defecation. The General Comfort Scale was planned to be re-administered on the 28th day of the intervention period.
The findings obtained from this study are expected to provide evidence regarding the potential role of constipation insoles as a complementary intervention in constipation management for patients in palliative care.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental Group | Experimental | Behavioral: constipation insole, Behavioral: WalkPatients in the experimental group were instructed to walk with the constipation insole for 20 minutes a day for four weeks, starting from the second week |
| Control Group | Other | Behavioral: WalkPatients in the control group were only instructed to walk for 20 minutes a day for four weeks. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Patients who volunteer to participate in the study and are over 18 years of age,
- Patients without any cognitive, mental, or verbal communication impairments,
- Patients receiving palliative care,
- Patients with constipation,
- Patients with fewer than 3 bowel movements per week and/or at least one of the following constipation problems (straining during bowel movements, hard stools, feeling of incomplete emptying, gas/bloating, pressure/feeling of needing to defecate in the rectum).
Key exclusion criteria (4 listed)
- Individuals with peripheral neuropathy,
- impaired foot skin integrity,
- flat feet or any foot deformity,
- and those using complementary treatments such as abdominal massage, acupressure, or acupuncture to relieve constipation were excluded from the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| constipation insolePatients in the experimental group were instructed to walk with the constipation insole for 20 minutes a day for four weeks, starting from the second week | Behavioural | Experimental Group |
| WalkPatients in the control group were only instructed to walk for 20 minutes a day for four weeks | Behavioural | Control Group, Experimental Group |
Primary outcome
Constipation Severity Scale
Time frame: First week
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Constipation Severity Scale
Time frame: second week
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Constipation Severity Scale
Time frame: third week
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Constipation Severity Scale
Time frame: fifth week
The Large Bowel Syndrome (LBS) consists of 16 questions in total and was developed to determine the frequency, intensity, and difficulty during defecation. The LBS comprises three sub-dimensions: "large bowel sluggishness," "fecal obstruction," and "pain." The highest possible score on the scale is 73. Scores for fecal obstruction range from 0-28, for large bowel sluggishness from 0-29, and for pain from 0-16.
Constipation Assessment Scale
Time frame: Baseline
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: third day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: sixth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: ninth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: twelfth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: fifteenth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: eighteenth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: twenty-first day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: twenty-fourth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: twenty-seventh day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Constipation Assessment Scale
Time frame: thirtieth day
This is a scale consisting of 8 items in total, which inquires about abdominal bloating, gas, bowel sounds, fecal incontinence, feeling of fullness/pressure in the rectum, pain during defecation, small or lumpy stools, and the presence of an urgent need to defecate but inability to do so.
Overall Comfort Scale
Time frame: Baseline
It is a scale developed to assess an individual's need for comfort. In the evaluation of the scale, negatively worded items are reverse-coded and summed together with the positively worded items. The highest possible total score on the scale is 192, while the lowest possible total score is 48. The total score obtained is divided by the number of items on the scale to calculate the mean score, which is expressed on a scale ranging from 1 to 4. A score of 1 indicates low comfort, whereas a score of 4 indicates high comfort.
Overall Comfort Scale
Time frame: thirty-fifth day
It is a scale developed to assess an individual's need for comfort. In the evaluation of the scale, negatively worded items are reverse-coded and summed together with the positively worded items. The highest possible total score on the scale is 192, while the lowest possible total score is 48. The total score obtained is divided by the number of items on the scale to calculate the mean score, which is expressed on a scale ranging from 1 to 4. A score of 1 indicates low comfort, whereas a score of 4 indicates high comfort.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jan 2026.
- BackgroundReferences Akyüz Özdemir, F., Can, G. 2024. "The Effect of Reflexology Socks in the Management of Opioid-Induced Constipation: A Randomized Controlled Trial", Cancer Nursing, 10-1097. Anjoman, A. Z., Mirghafourvand, M., Hughes, C., Havizari, S. 2021. "Effect of Foot Reflexology on Constipation: A Systematic Review and Meta-Analysis", [Dergi adı belirtilmemiş]. Arıkan Dirimen, G. 2016. "Palyatif Bakım Tanımı ve Felsefesi", Klinik Tıp Aile Hekimliği, 8(3), 1-5. Ayık Bıçak, D., Can, G. 2020. "Palyatif Bakım Hastalarında Konstipasyonun Yönetimi ve Akupresürün Etkinliği", Sağlık Akademisyenleri Dergisi, 7(2), 141-148. Barichella, M. et al. 2016. "Probiotics and Prebiotic Fiber for Constipation Associated with Parkinson Disease", Neurology, 87(12), 1274-1280. Bassotti, G., Battaglia, E. 2023. "Considerations for laxatives in terms of their interactions with other drugs", Expert Opinion on Drug Metabolism & Toxicology, 19(3), 121-123. Bayan, K. 2017. "Konstipasyona Güncel Yaklaşım", Klinik Tıp Bilimleri Dergisi, 5(2). Bharucha, A. E., Lacy, B. E. 2020. "Mechanisms, Evaluation, and Management of Chronic Constipation", Gastroenterology, 158(5), 1232-1249.e3. Camilleri, M. et al. 2017. "Chronic Constipation", Nature Reviews Disease Primers, 3, 1-19. Canbulat Şahiner, N., Demirgoz Bal, M. 2017. "A Randomized Controlled Trial Examining the Effects of Reflexology on Children With Functional Constipation", Gastroenterology Nursing, 40(5), 393-400. Candy, B. et al. 2015. "Laxatives for the Management of Constipation in People Receiving Palliative Care", Cochrane Database of Systematic Reviews, 5. Cevik, K. 2013. "Complementary and Alternative Therapy in Nursing: Reflexology", Ege Hemşirelik Fakültesi Dergisi, 29(2), 71-82. Cevik, K., Zaybak, A. 2018. "The Effect of Reflexology on Constipation in the Elderly", International Journal of Caring Science, 11(1), 309-318. Clark, K., Currow, D. C. 2013. "Constipation in Palliative Care: What Do We Use as Definitions and Outco
- Individual participant dataSharing planned: No. Patients have not given permission to share their data in this area.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing constipation insole and Walk in people with Palliative Care and Constipation, run by Istanbul Aydın University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Constipation Severity Scale (time frame: First week). The study lists 17 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07339293, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jan 2026.