Neck PainNPNCT07339683
Influence of Cervical Stabilization Exercises on Neural Tissue Mechanosensitivity in Patients With Chronic Nonspecific Neck Pain
A study testing cervical and scapulothoracic stabilization exercises. and traditional therapy in people with Neck Pain, run by Cairo University.
Trial summary
this study will be conducted to investigate the effect of cervical stabilization exercises on cervical pain intensity, upper limbs mechanosensitivity, cervicovertebral angle, and cervical proprioception in individuals with chronic nonspecific neck pain Read more about this study
- Who is it for?
- Ages 18 to 36 years
- Conditions the study is for
- Neck Pain
- What is being tested?
- cervical and scapulothoracic stabilization exercises. and traditional therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- No sites listed yet
- Study dates
- 15 Jan 2026to 25 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 36 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- participants with age range from 18 to 36 years and BMI from 25 to 30kg/m2 will be recruited
- Participants having neck pain symptoms provoked by neck postures, neck movement, or palpation of the cervical musculature, for 3 months
- Patients with a craniovertebral angle of less than 50º
Who cannot join
- History of previous injury of the neck.
- History of surgical intervention at the neck.
- History of inflammatory joint disease affecting facet joints
- participants with congenital disorders of the cervical spine.
- participants who received pain medication or physical therapy for their neck pain during the last 3 months.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
this study will be conducted to investigate the effect of cervical stabilization exercises on cervical pain intensity, upper limbs mechanosensitivity, cervicovertebral angle, and cervical proprioception in individuals with chronic nonspecific neck pain
Read the detailed description
Neck pain is the sensation of discomfort in the neck area. Neck pain can result from disorders of any of the structures in the neck, including the cervical vertebrae and intervertebral discs, nerves, muscles, blood vessels, esophagus, larynx, trachea, lymphatic organs, thyroid gland, or parathyroid glands.Forward head posture (FHP) is one of the commonly recognized types of poor head posture in the sagittal plane in patients with neck pain. FHP has been defined as 'any alignment in which the external auditory meatus is positioned anterior to the plumb line through the shoulder joint, with a general prevalence of about 64% in both males and females.Several studies reported the effect of cervical stabilization exercises on pain, ROM and cranio-cervical angle in patients with chronic non-specific neck pain. No studies have been concerned with measuring mechanosensitivity as an indicator technique of the effect of different modalities on chronic non-specific neck pain. With the proposal of the cervical and scapulothoracic stabilization program for patients with chronic non-specific neck pain secondary to forward head posture deviations.
- Conditions
- Neck Pain
- Being tested
- cervical and scapulothoracic stabilization exercises., traditional therapy
- Keywords
- cervical stabilization, tissue mechanosensitivity, neck pain
- Medical subject headings
- Neck Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
cervical and scapulothoracic stabilization exercises.Other
the patients will receive cervical and scapulothoracic stabilization exercises in the form of activation of deep cervical flexors in the first two weeks, followed by scapulothoracic muscles activation for the third and fourth weeks and finally group of exercises that emphasis on increasing difficulty and progress to quadruped and standing.
traditional therapyOther
the patients will receive traditional therapy in the form of ultrasound, hot pack, cervical extensors stretching and deep flexor strengthening
| Study group | Role | What they receive |
|---|---|---|
| cervical and scapulothoracic stabilization exercises. | Experimental | forty patients will receive cervical and scapulothoracic stabilization exercises plus traditional therapy three times a week for six weeks Receives: Other: cervical and scapulothoracic stabilization exercises.; Other: traditional therapy |
| traditional therapy | Active comparator | forty patients will receive traditional therapy three times a week for six weeks Receives: Other: traditional therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
mechanosensitivity of upper limb nerves
A handheld algometer will be used to assess mechanosensitivity. To apply this test test, specific points on the peripheral nerve trunks of the tested upper limb nerves will be identified through manual palpation, being easily accessible by the probe of the algometer and as they are commonly used sites of peripheral nerves' palpation with moderate inter-tester reliability. The supine lying posture will be assumed to test median and ulnar nerves, while sitting posture will be the choice for radial nerve. Median nerve will be located and tested in the antebrachial fossa just medial to the biceps brachii tendon. Ulnar will be tested in the cubital tunnel between humeral medial epicondyle and olecranon process, with the arm in 90º shoulder abduction as well as external rotation, and elbow flexion. Radial nerve palpation point lies between the middle and lower thirds of the humerus.
Measured: up to 6 weeks
Secondary outcomes (3)
craniovertebral angle
craniovertebral angle will be assessed by Kinovia software. Forward head posture will be determined when the craniovertebral angle is below 50 degrees (normal value).
Measured: up to 6 weeks
pain intensity
Visual analogue scale is the most commonly used method for assessing pain intensity. The left most value on the 10-cm horizontal line used for visual analogue scale indicates a painless condition, which is represented by 0. The rightmost value is 10, which represents extreme pain. The subjects will be in a relaxed position then will give them the appendix which contains VAS and rate their feelings of pain on the line by themselves, thereby quantifying the pain
Measured: up to six weeks
cervical joint position error (cervical proprioception)
To evaluate the joint position error , the examiner will hold the subject's head and moving slowly to the target head position, which is 50% of the maximum CROM and hold there for a period of 3 s. The subjects then memorized that target position and then the examiner slowly brought the subject's head back to the neutral position. The subjects then will be advised to reach the target position actively by moving the head and when subject reached the target position the reposition accuracy error will determine in degrees. The examiner will evaluate JPE tests in sagittal (flexion, extension) and transverse plane (right and left rotation) directions. Each direction of JPE testing will be performed three times and the mean error of these trials will be used in the analysis
Measured: up to six weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Jan 2026
- Study start15 Jan 2026 (estimated)
- Primary completion15 Jun 2026 (estimated)
- Study completion25 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neck PainStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- cervical and scapulothoracic stabilization exercises.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, nada ashraf mohamed zuhairy, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07339683
- Sponsor's protocol ID
- P.T.REC/012/005984
- Acronym
- NP
- Status last verified
- Jan 2026
- First submitted
- 5 Jan 2026
- Last updated
- 14 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Cervical Stabilization Exercises on Neural Tissue Mechanosensitivity in Patients With Chronic Nonspecific Neck Pain
- ClinicalTrials.gov ID
- NCT07339683
- Acronym / sponsor ID
- NP / P.T.REC/012/005984
- Conditions
- Neck Pain
- Keywords
- cervical stabilization, tissue mechanosensitivity, neck pain
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 15 Jan 2026 (estimated)
- Primary completion
- 15 Jun 2026 (estimated)
- Study completion
- 25 Jun 2026 (estimated)
- First posted
- 14 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study will be conducted to investigate the effect of cervical stabilization exercises on cervical pain intensity, upper limbs mechanosensitivity, cervicovertebral angle, and cervical proprioception in individuals with chronic nonspecific neck pain
Detailed description
Neck pain is the sensation of discomfort in the neck area. Neck pain can result from disorders of any of the structures in the neck, including the cervical vertebrae and intervertebral discs, nerves, muscles, blood vessels, esophagus, larynx, trachea, lymphatic organs, thyroid gland, or parathyroid glands.Forward head posture (FHP) is one of the commonly recognized types of poor head posture in the sagittal plane in patients with neck pain. FHP has been defined as 'any alignment in which the external auditory meatus is positioned anterior to the plumb line through the shoulder joint, with a general prevalence of about 64% in both males and females.Several studies reported the effect of cervical stabilization exercises on pain, ROM and cranio-cervical angle in patients with chronic non-specific neck pain. No studies have been concerned with measuring mechanosensitivity as an indicator technique of the effect of different modalities on chronic non-specific neck pain. With the proposal of the cervical and scapulothoracic stabilization program for patients with chronic non-specific neck pain secondary to forward head posture deviations.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- cervical and scapulothoracic stabilization exercises.
| Arm | Type | Receives |
|---|---|---|
| cervical and scapulothoracic stabilization exercises. | Experimental | Other: cervical and scapulothoracic stabilization exercises., Other: traditional therapyforty patients will receive cervical and scapulothoracic stabilization exercises plus traditional therapy three times a week for six weeks |
| traditional therapy | Active comparator | Other: traditional therapyforty patients will receive traditional therapy three times a week for six weeks |
Who may qualify
- Ages
- 18 to 36 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- participants with age range from 18 to 36 years and BMI from 25 to 30kg/m2 will be recruited
- Participants having neck pain symptoms provoked by neck postures, neck movement, or palpation of the cervical musculature, for 3 months
- Patients with a craniovertebral angle of less than 50º
Key exclusion criteria (5 listed)
- History of previous injury of the neck.
- History of surgical intervention at the neck.
- History of inflammatory joint disease affecting facet joints
- participants with congenital disorders of the cervical spine.
- participants who received pain medication or physical therapy for their neck pain during the last 3 months.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| cervical and scapulothoracic stabilization exercises.the patients will receive cervical and scapulothoracic stabilization exercises in the form of activation of deep cervical flexors in the first two weeks, followed by scapulothoracic muscles activation for the third and fourth weeks and finally group of exercises that emphasis on increasing difficulty and progress to quadruped and standing. | Other | cervical and scapulothoracic stabilization exercises. |
| traditional therapythe patients will receive traditional therapy in the form of ultrasound, hot pack, cervical extensors stretching and deep flexor strengthening | Other | cervical and scapulothoracic stabilization exercises., traditional therapy |
Primary outcome
mechanosensitivity of upper limb nerves
Time frame: up to 6 weeks
A handheld algometer will be used to assess mechanosensitivity. To apply this test test, specific points on the peripheral nerve trunks of the tested upper limb nerves will be identified through manual palpation, being easily accessible by the probe of the algometer and as they are commonly used sites of peripheral nerves' palpation with moderate inter-tester reliability. The supine lying posture will be assumed to test median and ulnar nerves, while sitting posture will be the choice for radial nerve. Median nerve will be located and tested in the antebrachial fossa just medial to the biceps brachii tendon. Ulnar will be tested in the cubital tunnel between humeral medial epicondyle and olecranon process, with the arm in 90º shoulder abduction as well as external rotation, and elbow flexion. Radial nerve palpation point lies between the middle and lower thirds of the humerus.
3 secondary outcomes
craniovertebral angle
Time frame: up to 6 weeks
pain intensity
Time frame: up to six weeks
cervical joint position error (cervical proprioception)
Time frame: up to six weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing cervical and scapulothoracic stabilization exercises. and traditional therapy in people with Neck Pain, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact nada zuhairy, phd (01014930018, nadazuhairy11@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
mechanosensitivity of upper limb nerves (time frame: up to 6 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Jan 2026.