Colo-rectal CancerNCT07342998
Could Computerized Tomography be an Alternative to Colonoscopies for Screening for Colorectal Cancer?
An observational study of Colo-rectal Cancer and Screening Colonscopy, run by Bilecik Seyh Edebali Universitesi at 1 site in Turkey (Türkiye).
Trial summary
The aim of this observational study is to investigate whether computed tomography can be used as an alternative to colonoscopy in colon cancer screening. The main question the study aims to answer is: Can colon cancer screening be performed as effectively with computed tomography as with colonoscopy? Participants in… Read more about this study
- Who is it for?
- Ages 50 to 70 years
- Conditions the study is for
- Colo-rectal Cancer, Screening Colonscopy, Colon Cancer Screening
- How many people
- 600 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jul 2025to Sep 2026
- How long will I take part?
- 1 Year
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: CT scans and colonoscopies performed on patients aged 50-70 at Bilecik Research and Training Hospital between January 1, 2023, and December 31, 2024, will be examined.
Who may be able to join
- All participants aged 50-70 who have undergone colonoscopy screening
- All participants aged 50-70 who have undergone abdominal computed tomography
Who cannot join
- The patient has a history of colon cancer
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Bilecik Seyh Edebali University
Bilecik, Bilecik, 11000
About this study
Official title: Could Computerized Tomography (CT) Scans be Used as an Alternative to Colonoscopies for Colorectal Cancer Screenings?
The aim of this observational study is to investigate whether computed tomography can be used as an alternative to colonoscopy in colon cancer screening. The main question the study aims to answer is:
Can colon cancer screening be performed as effectively with computed tomography as with colonoscopy?
Participants in the colon cancer screening group will be divided into two groups: those who underwent colonoscopy and those who underwent computed tomography. The screening effectiveness of the two methods will be compared.
- Keywords
- colonscopy, colon cancer, cancer screening
- Medical subject headings
- Colonic Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| colonscopy | participant screened by colonoscopy | |
| tomography | participant screened by tomography |
What is being measured
The primary outcome is the main question the study is designed to answer.
polyp/cancer incidance
Number of patients with polyps and cancer detected by screening
Measured: when the pathology results are available after a colonoscopy or when the report is written after a CT scan through study completion, an average of 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jan 2026
- Study start15 Jul 2025
- Primary completion1 Mar 2026 (estimated)
- Study completionSep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Colo-rectal CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 600 participants (estimated)
- Target duration
- 1 Year
Sponsor and investigators
- Lead sponsor
- Bilecik Seyh Edebali Universitesi
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mucahit UNAL, Bilecik Seyh Edebali Universitesi
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07342998
- Sponsor's protocol ID
- E-10333602-050.04-339197
- Status last verified
- Jan 2026
- First submitted
- 21 Dec 2025
- Last updated
- 15 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Mang T, Graser A, Schima W, Maier A. CT colonography: techniques, indications, findings. Eur J Radiol. 2007 Mar;61(3):388-99. doi: 10.1016/j.ejrad.2006.11.019. Epub 2007 Jan 16.
PubMed 17224254Terasawa T, Tadano T, Abe K, Sasaki S, Hosono S, Katayama T, Hoshi K, Nakayama T, Hamashima C. Single-round performance of colorectal cancer screening programs: a network meta-analysis of randomized clinical trials. BMC Med. 2025 Feb 21;23(1):110. doi: 10.1186/s12916-025-03948-9.
PubMed 39985068
Study at a glance
From the registry record, last updated by the sponsor on 15 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Could Computerized Tomography (CT) Scans be Used as an Alternative to Colonoscopies for Colorectal Cancer Screenings?
- ClinicalTrials.gov ID
- NCT07342998
- Acronym / sponsor ID
- E-10333602-050.04-339197
- Keywords
- colonscopy, colon cancer, cancer screening
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 600 participants (estimated)
- Lead sponsor
- Bilecik Seyh Edebali UniversitesiUniversity, hospital or other
- Study start
- 15 Jul 2025 (actual)
- Primary completion
- 1 Mar 2026 (estimated)
- Study completion
- Sep 2026 (estimated)
- First posted
- 15 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this observational study is to investigate whether computed tomography can be used as an alternative to colonoscopy in colon cancer screening. The main question the study aims to answer is:
Can colon cancer screening be performed as effectively with computed tomography as with colonoscopy?
Participants in the colon cancer screening group will be divided into two groups: those who underwent colonoscopy and those who underwent computed tomography. The screening effectiveness of the two methods will be compared.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Year
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| colonscopy | – | –participant screened by colonoscopy |
| tomography | – | –participant screened by tomography |
Who may qualify
- Ages
- 50 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- CT scans and colonoscopies performed on patients aged 50-70 at Bilecik Research and Training Hospital between January 1, 2023, and December 31, 2024, will be examined.
Key inclusion criteria (2 listed)
- All participants aged 50-70 who have undergone colonoscopy screening
- All participants aged 50-70 who have undergone abdominal computed tomography
Key exclusion criteria (1 listed)
- The patient has a history of colon cancer
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
polyp/cancer incidance
Time frame: when the pathology results are available after a colonoscopy or when the report is written after a CT scan through study completion, an average of 2 years
Number of patients with polyps and cancer detected by screening
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jan 2026.
- Results publication: PubMed 17224254Mang T, Graser A, Schima W, Maier A. CT colonography: techniques, indications, findings. Eur J Radiol. 2007 Mar;61(3):388-99. doi: 10.1016/j.ejrad.2006.11.019. Epub 2007 Jan 16.
- Results publication: PubMed 39985068Terasawa T, Tadano T, Abe K, Sasaki S, Hosono S, Katayama T, Hoshi K, Nakayama T, Hamashima C. Single-round performance of colorectal cancer screening programs: a network meta-analysis of randomized clinical trials. BMC Med. 2025 Feb 21;23(1):110. doi: 10.1186/s12916-025-03948-9.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Colo-rectal Cancer and Screening Colonscopy, run by Bilecik Seyh Edebali Universitesi at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 15 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
polyp/cancer incidance (time frame: when the pathology results are available after a colonoscopy or when the report is written after a CT scan through study completion, an average of 2 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07342998, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2026.