NutritionNCT07343518
Effects of Sulforaphane Supplementation on Athletic Performance
A study testing Fatigue protocol in people with Nutrition and Sports, run by University of Maia.
Trial summary
Considering the promising effects observed and the scarce and incipient scientific background of SFN in sports, the present study aims to evaluate the effects of SFN supplementation on fatigue, EIMD and recovery in trained individuals. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- What is being tested?
- Fatigue protocol
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 20 participants
- Where
- No sites listed yet
- Study dates
- 2 Jan 2026to 1 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Physically active individuals (engaging in exercise 3 or more times per week)
Who cannot join
- Individuals that experience musculoskeletal injuries or have experienced in the past 3 months
About this study
Official title: Effects of Sulforaphane Supplementation on Athletic Performance: a Double-blinded Randomized Crossover Study
Considering the promising effects observed and the scarce and incipient scientific background of SFN in sports, the present study aims to evaluate the effects of SFN supplementation on fatigue, EIMD and recovery in trained individuals. In particular, outcomes such as time to exhaustion (TTE), and perceptual questionnaires of muscle soreness, recovery, and fatigue will be assessed, aiming to explore the effectiveness of SFN.
- Being tested
- Fatigue protocol
- Keywords
- sulforaphane, fatigue, athletic performance
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Fatigue protocolOther
Fatigue protocol comprising 6 sets of 30 seconds at 120% of velocity of maximal oxygen consumption
| Study group | Role | What they receive |
|---|---|---|
| Sulforaphane | Experimental | Sulforaphane supplementation (Nomio) Receives: Other: Fatigue protocol |
| Placebo | Placebo comparator | Placebo intervention Receives: Other: Fatigue protocol |
What is being measured
The primary outcome is the main question the study is designed to answer.
time to exhaustion
Measured: 24 hours
Secondary outcomes (4)
Rating of Fatigue Scale
Measured: Baseline, 30 minutes, 24 hours
Total Quality Recovery Scale
Measured: Baseline, 30 minutes, 24 hours
Muscle soreness (Visual analogue scale)
Measured: Baseline, 30 minutes, 24 hours
Rating of perceived exertion scale
Measured: 30 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jan 2026
- Study start2 Jan 2026 (estimated)
- Primary completion1 Apr 2026 (estimated)
- Study completion1 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for NutritionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Maia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Filipe Silvano Pinto Maia, University of Maia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07343518
- Sponsor's protocol ID
- SFN_001
- Status last verified
- Jan 2026
- First submitted
- 20 Dec 2025
- Last updated
- 15 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 15 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Sulforaphane Supplementation on Athletic Performance: a Double-blinded Randomized Crossover Study
- ClinicalTrials.gov ID
- NCT07343518
- Acronym / sponsor ID
- SFN_001
- Keywords
- sulforaphane, fatigue, athletic performance
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- University of MaiaUniversity, hospital or other
- Study start
- 2 Jan 2026 (estimated)
- Primary completion
- 1 Apr 2026 (estimated)
- Study completion
- 1 May 2026 (estimated)
- First posted
- 15 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Considering the promising effects observed and the scarce and incipient scientific background of SFN in sports, the present study aims to evaluate the effects of SFN supplementation on fatigue, EIMD and recovery in trained individuals. In particular, outcomes such as time to exhaustion (TTE), and perceptual questionnaires of muscle soreness, recovery, and fatigue will be assessed, aiming to explore the effectiveness of SFN.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Sulforaphane | Experimental | Other: Fatigue protocolSulforaphane supplementation (Nomio) |
| Placebo | Placebo comparator | Other: Fatigue protocolPlacebo intervention |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Physically active individuals (engaging in exercise 3 or more times per week)
Key exclusion criteria (1 listed)
- Individuals that experience musculoskeletal injuries or have experienced in the past 3 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Fatigue protocolFatigue protocol comprising 6 sets of 30 seconds at 120% of velocity of maximal oxygen consumption | Other | Placebo, Sulforaphane |
Primary outcome
time to exhaustion
Time frame: 24 hours
4 secondary outcomes
Rating of Fatigue Scale
Time frame: Baseline, 30 minutes, 24 hours
Total Quality Recovery Scale
Time frame: Baseline, 30 minutes, 24 hours
Muscle soreness (Visual analogue scale)
Time frame: Baseline, 30 minutes, 24 hours
Rating of perceived exertion scale
Time frame: 30 minutes
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jan 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Fatigue protocol in people with Nutrition and Sports, run by University of Maia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 15 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
time to exhaustion (time frame: 24 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2026; AzTrials last refreshed its copy on 5 Nov 2026.