AdultNCT07344545
Mining the Gut Microbiota of Adults for Health-relevant Microbial Signatures.
An observational study of Adult, run by Zhujiang Hospital at 1 site in China.
Trial summary
Mining the gut microbiota of adults for health-relevant microbial signatures. Read more about this study
- Who is it for?
- Ages 30 to 95 yearsHealthy volunteers can take part
- Conditions the study is for
- Adult
- What is being tested?
- Observational, non-interventional study.
- How many people
- 1,530 participants
- Where
- 1 siteChina
- Study dates
- 15 Aug 2021to 29 Sep 2021
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 95 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Meet eligibility criteria
Who may be able to join
- Community-dwelling adults aged 30 to 95 years.
- Individuals who underwent an annual health examination at the Health Management Center of Huzhou Central Hospital during the specified time period.
- Ability to comprehend the study content and voluntarily provide signed informed consent.
- Willingness and ability to provide the required biospecimens (blood, urine, stool).
Who cannot join
- Concurrent participation in another interventional clinical trial that is likely to interfere with the results of this study.
- Voluntary withdrawal from the study.
Trial locations and contacts
1 site in 1 country.
China1 site
Zhujiang Hospital of Southern Medical University
Guangzhou, Guangdong, 510000
About this study
Official title: Identification of Gut Microbiota Signatures Associated With Health Metrics in a Community-based Adult Cohort: a Cross-sectional Study
Mining the gut microbiota of adults for health-relevant microbial signatures.
Read the detailed description
This study is a community-based, observational cross-sectional investigation, enrolling 1,530 middle-aged and elderly volunteers.
Data were collected through a systematic, multi-dimensional assessment, which included:
Biospecimen Collection: Blood, urine, and stool samples were obtained from the volunteers.
Physical and Imaging Examinations: Procedures included anthropometric measurements, vital sign monitoring, oral examinations, electrocardiograms, physical examinations of key organs, and abdominal ultrasonography.
Psychological and Cognitive Assessments: Standardized scales were administered to assess anxiety/depression and memory function.
All clinical and questionnaire data were processed through standardized procedures, forming a comprehensive health database for subsequent analysis.
- Conditions
- Adult
- Being tested
- Observational, non-interventional study.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Observational, non-interventional study.Other
Observational, non-interventional study.
| Study group | Role | What they receive |
|---|---|---|
| adult volunteers | The study population consists of 1,530 middle-aged and elderly volunteers from the same community who underwent comprehensive health examinations at Huzhou Central Hospital . All participants completed a multi-dimensional assessment including biospecimen collection, physical/imaging examinations, and psychometric evaluations. Receives: Other: Observational, non-interventional study. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Identification of Health-Relevant Signatures in Adults
Primary Outcome Measure 1)Change in standard laboratory parameters from baseline:Changes in routine laboratory parameters measured in blood, urine, and stool samples, including complete blood count and standard serum biochemistry panels.Unit of Measure: Various laboratory units (e.g., g/L, U/L, mmol/L); 2) Change in anthropometric measurements from baseline: Anthropometric measurements including body weight (kg), height (m), and body mass index (BMI, kg/m²).Unit of Measure:kg, m, kg/m²; 3) Alcohol consumption status: Alcohol consumption status assessed by self- report, categorized as current drinker or non-drinker at enrollment.Unit of Measure:Categorical (yes/no); 4) Hospital Anxiety and Depression Scale (HADS) scores: Anxiety and depression symptom severity assessed using the Hospital Anxiety and Depression Scale, including anxiety and depression subscale scores.Unit of Measure:Score on a standardized scale.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jan 2026
- Study start15 Aug 2021
- Primary completion30 Aug 2021
- Study completion29 Sep 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AdultStudies of the same condition, open and under way.
- More trials run by Zhujiang HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 1,530 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zhujiang Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Huzhou Central Hospital
- Responsible party
- Principal investigator, Xiaolong He, Zhujiang Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07344545
- Sponsor's protocol ID
- Zhujiang-Huzhou
- Status last verified
- Dec 2025
- First submitted
- 3 Dec 2025
- Last updated
- 15 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Identification of Gut Microbiota Signatures Associated With Health Metrics in a Community-based Adult Cohort: a Cross-sectional Study
- ClinicalTrials.gov ID
- NCT07344545
- Acronym / sponsor ID
- Zhujiang-Huzhou
- Conditions
- Adult
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,530 participants (actual)
- Lead sponsor
- Zhujiang HospitalUniversity, hospital or other
- Collaborators
- Huzhou Central Hospital
- Study start
- 15 Aug 2021 (actual)
- Primary completion
- 30 Aug 2021 (actual)
- Study completion
- 29 Sep 2021 (actual)
- First posted
- 15 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Mining the gut microbiota of adults for health-relevant microbial signatures.
Detailed description
This study is a community-based, observational cross-sectional investigation, enrolling 1,530 middle-aged and elderly volunteers.
Data were collected through a systematic, multi-dimensional assessment, which included:
Biospecimen Collection: Blood, urine, and stool samples were obtained from the volunteers.
Physical and Imaging Examinations: Procedures included anthropometric measurements, vital sign monitoring, oral examinations, electrocardiograms, physical examinations of key organs, and abdominal ultrasonography.
Psychological and Cognitive Assessments: Standardized scales were administered to assess anxiety/depression and memory function.
All clinical and questionnaire data were processed through standardized procedures, forming a comprehensive health database for subsequent analysis.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| adult volunteers | – | Other: Observational, non-interventional study.The study population consists of 1,530 middle-aged and elderly volunteers from the same community who underwent comprehensive health examinations at Huzhou Central Hospital . All participants completed a multi-dimensional assessment including biospecimen collection, physical/imaging examinations, and psychometric evaluations. |
Who may qualify
- Ages
- 30 to 95 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Meet eligibility criteria
Key inclusion criteria (4 listed)
- Community-dwelling adults aged 30 to 95 years.
- Individuals who underwent an annual health examination at the Health Management Center of Huzhou Central Hospital during the specified time period.
- Ability to comprehend the study content and voluntarily provide signed informed consent.
- Willingness and ability to provide the required biospecimens (blood, urine, stool).
Key exclusion criteria (2 listed)
- Concurrent participation in another interventional clinical trial that is likely to interfere with the results of this study.
- Voluntary withdrawal from the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Observational, non-interventional study.Observational, non-interventional study. | Other | adult volunteers |
Primary outcome
Identification of Health-Relevant Signatures in Adults
Time frame: Baseline
Primary Outcome Measure 1)Change in standard laboratory parameters from baseline:Changes in routine laboratory parameters measured in blood, urine, and stool samples, including complete blood count and standard serum biochemistry panels.Unit of Measure: Various laboratory units (e.g., g/L, U/L, mmol/L); 2) Change in anthropometric measurements from baseline: Anthropometric measurements including body weight (kg), height (m), and body mass index (BMI, kg/m²).Unit of Measure:kg, m, kg/m²; 3) Alcohol consumption status: Alcohol consumption status assessed by self- report, categorized as current drinker or non-drinker at enrollment.Unit of Measure:Categorical (yes/no); 4) Hospital Anxiety and Depression Scale (HADS) scores: Anxiety and depression symptom severity assessed using the Hospital Anxiety and Depression Scale, including anxiety and depression subscale scores.Unit of Measure:Score on a standardized scale.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Adult, run by Zhujiang Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 15 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Identification of Health-Relevant Signatures in Adults (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2026.