ConstipationSIJ disordersNCT07344571
Investigating the Correlation Between Functional Constipation and Sacroiliac Joint Disorders
An observational study of Constipation, run by Middle East University at 1 site in Egypt.
Trial summary
Constipation is a common gastrointestinal issue affecting individuals worldwide. Interferential therapy, a form of electrotherapy, has been suggested to have potential benefits in improving gastrointestinal motility and relieving constipation symptoms. Read more about this study
- Who is it for?
- Ages 25 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Constipation
- How many people
- 200 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Apr 2023to 10 Sep 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: male and female participant
Who may be able to join
- history of Chronic Constipation (CC), as defined by either experiencing two or fewer Complete Spontaneous Bowel Movements (CSBMs) per week for a minimum of 6 consecutive months before the screening visit
- Reporting a sensation of incomplete evacuation or straining during at least a quarter of their bowel movements (according to the generally accepted definition of constipation).
- Patients must have had CC persisting for more than 6 months, failed to respond to or be intolerant of medical treatment for at least 3 months
- Not having functional constipation
Who cannot join
- - pregnant or lactating women
- Chronic Constipation (CC) resulting from anorectal malformations such as colorectal or anal organic lesions, pelvic floor disorders requiring surgical intervention as determined by the investigator (such as rectal prolapse, rectocele, or enterocele)
- presence of implanted electronic devices like cardiac pacemakers, defibrillators, cardiac pumps, or spinal stimulators
- CC attributable to medications or neurologic, endocrine, or metabolic conditions
- prior history of partial colectomy; conditions like megacolon, megarectum, or colonic inertia
- skin abnormalities that hinder the placement of electrodes
- women lacking adequate contraception (hormonal or intrauterine device).
Trial locations and contacts
1 site in 1 country.
About this study
Constipation is a common gastrointestinal issue affecting individuals worldwide. Interferential therapy, a form of electrotherapy, has been suggested to have potential benefits in improving gastrointestinal motility and relieving constipation symptoms. Introducing of a new method like electronic cupping therapy with interferential therapy may optimize the therapeutic outcomes by potentially increasing bowel movements and improving overall gastrointestinal function.
Read the detailed description
Objective: The purpose of this study was to Investigate the correlation between functional constipation and sacroiliac joint disorders Methods: This study involved 200 patients with chronic constipation, consisting of 120 females and 80 males, ranging in age from 25 to 60 years. All participants were allocated into two groups: Group (A) patients with constipation, Group (B) patients without constipation
- Conditions
- Constipation
- Keywords
- constipation, sacroiliac joint disorders
- Medical subject headings
- Constipation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| group A: Patients with constipation | Both the rectum and the sacroiliac joint share innervation from sacral spinal segments S2-S4. Neural signals from the rectum can influence SI joint sensory nerves via viscerosomatic and somatovisceral reflex arcs. This means chronic constipation may both result from and contribute to SI joint dysfunction. | |
| group B: Patients without constipation | Accumulated stool in the rectum and sigmoid colon can physically press on pelvic structures, stretching ligaments and tensioning muscles around the SI joint. This may trigger or mimic SI joint dysfunction. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Distraction Test (SI Joint Gapping)
Position of patient: Supine. force: posterior-lateral force to both ASISs at same time results: pain in SI region
Measured: 6 months
Thigh Thrust Test
Position of patient: Supine, hip and knee of affected side flexed 90°. force: Stabilize opposite ASIS, apply posterior force through femur. result: Focal SI pain.
Measured: 6 months
Sacral Thrust Test
Position of patient: Prone. force: Apply an anterior shear force to sacrum (over S2). result: Reproduction of pain in SI region.
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jan 2026
- Study start15 Apr 2023
- Primary completion10 Sep 2026 (estimated)
- Study completion10 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ConstipationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Middle East University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Emad Eldin Mohamed, Middle East University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07344571
- Sponsor's protocol ID
- 2517
- Acronym
- SIJ disorders
- Status last verified
- Jan 2026
- First submitted
- 1 Jan 2026
- Last updated
- 15 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigating the Correlation Between Functional Constipation and Sacroiliac Joint Disorders
- ClinicalTrials.gov ID
- NCT07344571
- Acronym / sponsor ID
- SIJ disorders / 2517
- Conditions
- Constipation
- Keywords
- constipation, sacroiliac joint disorders
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Middle East UniversityUniversity, hospital or other
- Study start
- 15 Apr 2023 (actual)
- Primary completion
- 10 Sep 2026 (estimated)
- Study completion
- 10 Sep 2026 (estimated)
- First posted
- 15 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Constipation is a common gastrointestinal issue affecting individuals worldwide. Interferential therapy, a form of electrotherapy, has been suggested to have potential benefits in improving gastrointestinal motility and relieving constipation symptoms. Introducing of a new method like electronic cupping therapy with interferential therapy may optimize the therapeutic outcomes by potentially increasing bowel movements and improving overall gastrointestinal function.
Detailed description
Objective: The purpose of this study was to Investigate the correlation between functional constipation and sacroiliac joint disorders Methods: This study involved 200 patients with chronic constipation, consisting of 120 females and 80 males, ranging in age from 25 to 60 years. All participants were allocated into two groups: Group (A) patients with constipation, Group (B) patients without constipation
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| group A: Patients with constipation | – | –Both the rectum and the sacroiliac joint share innervation from sacral spinal segments S2-S4. Neural signals from the rectum can influence SI joint sensory nerves via viscerosomatic and somatovisceral reflex arcs. This means chronic constipation may both result from and contribute to SI joint dysfunction. |
| group B: Patients without constipation | – | –Accumulated stool in the rectum and sigmoid colon can physically press on pelvic structures, stretching ligaments and tensioning muscles around the SI joint. This may trigger or mimic SI joint dysfunction. |
Who may qualify
- Ages
- 25 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- male and female participant
Key inclusion criteria (4 listed)
- history of Chronic Constipation (CC), as defined by either experiencing two or fewer Complete Spontaneous Bowel Movements (CSBMs) per week for a minimum of 6 consecutive months before the screening visit
- Reporting a sensation of incomplete evacuation or straining during at least a quarter of their bowel movements (according to the generally accepted definition of constipation).
- Patients must have had CC persisting for more than 6 months, failed to respond to or be intolerant of medical treatment for at least 3 months
- Not having functional constipation
Key exclusion criteria (7 listed)
- - pregnant or lactating women
- Chronic Constipation (CC) resulting from anorectal malformations such as colorectal or anal organic lesions, pelvic floor disorders requiring surgical intervention as determined by the investigator (such as rectal prolapse, rectocele, or enterocele)
- presence of implanted electronic devices like cardiac pacemakers, defibrillators, cardiac pumps, or spinal stimulators
- CC attributable to medications or neurologic, endocrine, or metabolic conditions
- prior history of partial colectomy; conditions like megacolon, megarectum, or colonic inertia
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Distraction Test (SI Joint Gapping)
Time frame: 6 months
Position of patient: Supine. force: posterior-lateral force to both ASISs at same time results: pain in SI region
Thigh Thrust Test
Time frame: 6 months
Position of patient: Supine, hip and knee of affected side flexed 90°. force: Stabilize opposite ASIS, apply posterior force through femur. result: Focal SI pain.
Sacral Thrust Test
Time frame: 6 months
Position of patient: Prone. force: Apply an anterior shear force to sacrum (over S2). result: Reproduction of pain in SI region.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Constipation, run by Middle East University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 15 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Distraction Test (SI Joint Gapping) (time frame: 6 months). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2026.