HealthyVORNCT07347470
The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial "VOR - Vestibulo-ocular Reflex"
A study testing Rhythmic auditory stimulation and Silence in people with Healthy, run by University of Haifa at 1 site in Israel.
Trial summary
The goal of this study is to learn whether adding rhythmic sound (a metronome beat or music) to eye-head exercises can improve the reflex that keeps vision clear during head movement. Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Rhythmic auditory stimulation and Silence
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 13 participants
- Where
- 1 siteIsrael
- Study dates
- 15 Dec 2025to 20 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy
Who cannot join
- Vestibular disorders. Neurologic conditions, Deafness, Blindness
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Dancing Eyes: The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial
The goal of this study is to learn whether adding rhythmic sound (a metronome beat or music) to eye-head exercises can improve the reflex that keeps vision clear during head movement. This reflex, called the vestibulo-ocular reflex (VOR), helps maintain visual stability during activities such as walking, turning, or bending. This type of training may help people with dizziness or balance problems, but this study focuses on healthy adults.
The main questions addressed are:
Read more
Does performing VOR exercises with a steady metronome beat improve the VOR more than performing the same exercises in silence?
Does performing the exercises while listening to self-selected rhythmic music also improve the VOR, and is the effect better or worse than a metronome?
Do the different sound conditions change how difficult the training feels or how dizzy participants feel?
Three conditions will be compared:
Silence: standard VOR training with no sound Metronome: training timed to a simple, steady beat Music: training performed while listening to self-selected music with a clear beat
The study will assess whether adding rhythmic sound leads to greater improvement in VOR gain and whether one type of sound is more effective than another.
Participants are healthy adults. Participants will:
Attend the laboratory for three separate visits, each with a different sound condition (silence, metronome, and music).
Visits will be at least 48 hours apart.
Wear specialized goggles that record eye and head movements (EyeSeeCam).
Perform brief eye-head tests before and after training, consisting of rapid head turns while maintaining fixation on a visual target.
Complete 15 minutes of Incremental VOR adaptation training during each visit, repeating rapid head turns while fixating on a laser projected target (StableEyes). In some sessions movements will be synchronized to a metronome or music.
Rate perceived training difficulty, ease of following the rhythm, and any dizziness or discomfort.
By comparing results across the three conditions within the same participants, the study will determine whether a simple, low-cost rhythmic cue can enhance the effects of standard VOR exercises without increasing discomfort.
- Conditions
- Healthy
- Being tested
- Rhythmic auditory stimulation, Silence
- Keywords
- Vestibular adaptation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Rhythmic auditory stimulationOther
the same 15 minutes of vestibular adaptation training will be completed by all participants in 3 different conditions: silence, metronome, and music. participants will be instructed to synchronize their head impulses to the beat in the auditory conditions.
SilenceOther
15 minutes of vestibular adaptation training without any background noise.
| Study group | Role | What they receive |
|---|---|---|
| Silence | Active comparator | Complete 15 minutes of vestibular adaptation training in silent condition Receives: Other: Silence |
| Metronome | Experimental | 15 minutes of vestibular adaptation training with metronome beat played in the background Receives: Other: Rhythmic auditory stimulation |
| Music | Experimental | 15 minutes of vestibular adaptation training with music played in the background Receives: Other: Rhythmic auditory stimulation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in horizontal semicircular canal VOR gain for active and passive head impulses
The change in vestibulo-ocular reflex (VOR) gain for the horizontal semicircular canals, measured using video head impulse testing (vHIT), calculated as the difference between pre-training and post-training gain values for both active and passive head impulses under each auditory condition (Silence, Metronome, and Music).
Measured: Gains values- Baseline (pre-training) and immediately after each training session (post-training). Assessed during each of the three sessions. The sessions are separated by at least 48 hours and all three will be completed over approximately 2 - 4 weeks.
Secondary outcomes (1)
Self-reported training difficulty and adverse symptoms
Participant-reported ratings of training difficulty and adverse symptoms (including dizziness and nausea), assessed using 1-10 visual analog scales completed after each training session under each of the three auditory conditions.
Measured: Immediately after completion of each of the three training sessions. Sessions will be separated by at least 48 hours and all three will be completed over approximately 2-4 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jan 2026
- Study start15 Dec 2025
- Primary completion1 Feb 2026
- Study completion20 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- Participants will undergo vestibular adaptation training in 3 different conditions at least 48 hours apart - Silence, Metronome, and Music. the order will be randomly allocated.
- Masking
- None (open label)
- Enrolment
- 13 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Haifa
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07347470
- Sponsor's protocol ID
- SMC-0074-23
- Acronym
- VOR
- Status last verified
- Sep 2026
- First submitted
- 15 Dec 2025
- Last updated
- 16 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Dancing Eyes: The Effect of Rhythmic Auditory Stimulation on VOR Gain Adaptation Among Healthy Adults - A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07347470
- Acronym / sponsor ID
- VOR / SMC-0074-23
- Conditions
- Healthy
- Keywords
- Vestibular adaptation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 13 participants (actual)
- Lead sponsor
- University of HaifaUniversity, hospital or other
- Study start
- 15 Dec 2025 (actual)
- Primary completion
- 1 Feb 2026 (actual)
- Study completion
- 20 Feb 2026 (actual)
- First posted
- 16 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to learn whether adding rhythmic sound (a metronome beat or music) to eye-head exercises can improve the reflex that keeps vision clear during head movement. This reflex, called the vestibulo-ocular reflex (VOR), helps maintain visual stability during activities such as walking, turning, or bending. This type of training may help people with dizziness or balance problems, but this study focuses on healthy adults.
The main questions addressed are:
Does performing VOR exercises with a steady metronome beat improve the VOR more than performing the same exercises in silence?
Does performing the exercises while listening to self-selected rhythmic music also improve the VOR, and is the effect better or worse than a metronome?
Do the different sound conditions change how difficult the training feels or how dizzy participants feel?
Three conditions will be compared:
Silence: standard VOR training with no sound Metronome: training timed to a simple, steady beat Music: training performed while listening to self-selected music with a clear beat
The study will assess whether adding rhythmic sound leads to greater improvement in VOR gain and whether one type of sound is more effective than another.
Participants are healthy adults. Participants will:
Attend the laboratory for three separate visits, each with a different sound condition (silence, metronome, and music).
Visits will be at least 48 hours apart.
Wear specialized goggles that record eye and head movements (EyeSeeCam).
Perform brief eye-head tests before and after training, consisting of rapid head turns while maintaining fixation on a visual target.
Complete 15 minutes of Incremental VOR adaptation training during each visit, repeating rapid head turns while fixating on a laser projected target (StableEyes). In some sessions movements will be synchronized to a metronome or music.
Rate perceived training difficulty, ease of following the rhythm, and any dizziness or discomfort.
By comparing results across the three conditions within the same participants, the study will determine whether a simple, low-cost rhythmic cue can enhance the effects of standard VOR exercises without increasing discomfort.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Participants will undergo vestibular adaptation training in 3 different conditions at least 48 hours apart - Silence, Metronome, and Music. the order will be randomly allocated.
| Arm | Type | Receives |
|---|---|---|
| Silence | Active comparator | Other: SilenceComplete 15 minutes of vestibular adaptation training in silent condition |
| Metronome | Experimental | Other: Rhythmic auditory stimulation15 minutes of vestibular adaptation training with metronome beat played in the background |
| Music | Experimental | Other: Rhythmic auditory stimulation15 minutes of vestibular adaptation training with music played in the background |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Healthy
Key exclusion criteria (1 listed)
- Vestibular disorders. Neurologic conditions, Deafness, Blindness
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Rhythmic auditory stimulationthe same 15 minutes of vestibular adaptation training will be completed by all participants in 3 different conditions: silence, metronome, and music. participants will be instructed to synchronize their head impulses to the beat in the auditory conditions. | Other | Metronome, Music |
| Silence15 minutes of vestibular adaptation training without any background noise. | Other | Silence |
Primary outcome
Change in horizontal semicircular canal VOR gain for active and passive head impulses
Time frame: Gains values- Baseline (pre-training) and immediately after each training session (post-training). Assessed during each of the three sessions. The sessions are separated by at least 48 hours and all three will be completed over approximately 2 - 4 weeks.
The change in vestibulo-ocular reflex (VOR) gain for the horizontal semicircular canals, measured using video head impulse testing (vHIT), calculated as the difference between pre-training and post-training gain values for both active and passive head impulses under each auditory condition (Silence, Metronome, and Music).
1 secondary outcome
Self-reported training difficulty and adverse symptoms
Time frame: Immediately after completion of each of the three training sessions. Sessions will be separated by at least 48 hours and all three will be completed over approximately 2-4 weeks.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Sep 2026.
Related trials for Healthy
Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Physical Activity, Body Image
Not yet recruitingPhase 1
A Phase I Study of GLR2053 Tablets in Chinese Healthy Adult Participants
Atopic Dermatitis
Recruiting
Colon-delivered Riboflavin and Gut Microbiota Composition
Microbiome Dysbiosis, Gut Health
Not yet recruiting
Neuroergonomic Analysis of a Brain-Computer Interface Device (BCI)
Healthy Volunteers - Male and Female
RecruitingPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy Volunteer, Atopic Dermatitis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Rhythmic auditory stimulation and Silence in people with Healthy, run by University of Haifa at 1 site in Israel.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Israel. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in horizontal semicircular canal VOR gain for active and passive head impulses (time frame: Gains values- Baseline (pre-training) and immediately after each training session (post-training). Assessed during each of the three sessions. The sessions are separated by at least 48 hours and all three will be completed over approximately 2 - 4 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Sep 2026.