StretchingHIPROTNCT07350434
Hip Abduction and Adduction During Neurodynamic Stretching
A study testing Maximal neurodynamic flossing in people with Stretching and Control Condition, run by University of Burgundy at 1 site in France.
Trial summary
Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves. Two main approaches are distinguished : Nerve tensioning and nerve flossing. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Stretching, Control Condition
- What is being tested?
- Maximal neurodynamic flossing
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 12 participants
- Where
- 1 siteFrance
- Study dates
- 1 Feb 2026to 30 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- healthy
- physical active
- no injuries (lower limb or back pain) in the past 3 months
Who cannot join
- Specific lower limb (hamstring) injuries in the past 2 years
- Not restraining activity 24h before participation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Universite Bourgogne Europe - faculty of sports sciences
Dijon
Nicolas Babault, +33380396743, nicolas.babault@ube.fr
About this study
Official title: The Acute Effects of Neurodynamic Stretching on the Shear Wave Velocity: the Effects of Hip Adduction and Abduction
Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves. Two main approaches are distinguished : Nerve tensioning and nerve flossing. They both involve proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the position that should be used. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).
Read the detailed description
Neurodynamic mobilization techniques are frequently applied in rehabilitation settings to enhance the mobility and function of peripheral nerves, particularly in the management of neuropathic pain such as carpal tunnel syndrome, radiculopathies, or sciatica. Two main approaches are distinguished. Nerve tensioning involves maintaining the nerve stretched at the end of the joint range of motion with relatively limited excursion. It is similar to a static stretching intervention but with distal (ankle) and proximal (cervical) tensions. Nerve flossing (also termed gliding or sliders), consists of alternating proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. Both techniques appear efficient. However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the angular position that could be used. For instance, hip rotations or hip adduction could impact muscle or nerve tissue changes, particularly in healthy tissues. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Performed in patients, healthy or athletes, no study has compared different hip positions. Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography). This method has been shown reliable to provide non-invasive real-time assessments of soft tissues elastic properties.
- Conditions
- Stretching, Control Condition
- Being tested
- Maximal neurodynamic flossing
- Keywords
- stretching, stiffness, nerve, muscle, flexibility, hip
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Maximal neurodynamic flossingOther
Neurodynamic flossing was applied at pain threshold on hamstring muscles and repeated 5 times during 60s at the point of pain. During the neurodynamic conditions, head and ankle movement permitted to mobilize nerve tissues. Flossing is the alternation of these movements every 2 seconds.
| Study group | Role | What they receive |
|---|---|---|
| No intervention (neutral) | No intervention | No intervention with measurements in neutral position |
| No intervention (adduction) | No intervention | No intervention with measurements in adduction position |
| No intervention (abduction) | No intervention | No intervention with measurements in abduction position |
| Neurodynamic (neutral) | Active comparator | The hip was positioned neutral (alignment between the lower limb and the trunk). Receives: Other: Maximal neurodynamic flossing |
| Neurodynamic (adduction) | Experimental | The hip was positioned in adduction and the neurodynamic stretch was applied. Receives: Other: Maximal neurodynamic flossing |
| Neurodynamic (abduction) | Experimental | The hip was positioned in abduction and the neurodynamic stretch was applied. Receives: Other: Maximal neurodynamic flossing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Nerve shear wave velocity using elastography in neutral position
Shear wave velocity of the sciatic nerve will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography". Briefly, the ultrasound probe will deliver an ultrasound wave. The propagation speed (called '"shear wave velocity") will be measured by the same probe. The greater the velocity is, the harder the tissue is. The hip position was neutral (alignment between the lower limb and the trunk).
Measured: Before the intervention and at the end (immediately after) the intervention
Secondary outcomes (10)
Nerve shear wave velocity using elastography in experimental position
Shear wave velocity of the sciatic nerve will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography". Briefly, the ultrasound probe will deliver an ultrasound wave. The propagation speed (called '"shear wave velocity") will be measured by the same probe. The greater the velocity is, the harder the tissue is. The hip position was the experimental position (i.e., adduction or abduction depending on the randomisation).
Measured: Before the intervention and at the end (immediately after) the intervention
Muscle shear wave velocity using elastography in neutral position
Shear wave velocity of the biceps femoris muscle will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography". Briefly, the ultrasound probe will deliver an ultrasound wave. The propagation speed (called '"shear wave velocity") will be measured by the same probe. The greater the velocity is, the harder the tissue is. The hip position was neutral (alignment between the lower limb and the trunk).
Measured: Before the intervention and at the end (immediately after) the intervention
Muscle shear wave velocity using elastography in the experimental position
Shear wave velocity of the biceps femoris muscle will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography". Briefly, the ultrasound probe will deliver an ultrasound wave. The propagation speed (called '"shear wave velocity") will be measured by the same probe. The greater the velocity is, the harder the tissue is. The hip position was the experimental position (i.e., adduction or abduction depending on the randomisation).
Measured: Before the intervention and at the end (immediately after) the intervention
Hamstring force
Maximal torque during a maximal voluntary hamstring contraction
Measured: Before the intervention and at the end (immediately after) the intervention
Biceps femoris electromyographic activity
Electromyographic activity of biceps femoris muscle
Measured: Before the intervention and at the end (immediately after) the intervention
Semitendinosus electromyographic activity
Electromyographic activity of semitendinosus
Measured: Before the intervention and at the end (immediately after) the intervention
passive knee extension
The final passive range of motion of the hamstring muscles
Measured: Before the intervention and at the end (immediately after) the intervention
Global flexibility
the stand and reach test to evaluate flexibility (in centimeters)
Measured: Before the intervention and at the end (immediately after) the intervention
Slump test
Seated flexibility using the slump test (in degrees)
Measured: Before the intervention and at the end (immediately after) the intervention
discomfort
rating of perceived discomfort during the intervention (from 1 to 10, no discomfort to maximal discomfort, respectively)
Measured: At the end (immediately after) the intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start1 Feb 2026
- Primary completion10 Feb 2026
- Study completion30 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StretchingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 12 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Burgundy
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nicolas Babault, University of Burgundy
- Investigators
- Nicolas Babault, Principal investigator, universite bourgogne europe
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07350434
- Sponsor's protocol ID
- CEP2601
- Acronym
- HIPROT
- Status last verified
- Apr 2026
- First submitted
- 9 Jan 2026
- Last updated
- 28 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: data freely available in online websites
Study at a glance
From the registry record, last updated by the sponsor on 28 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Acute Effects of Neurodynamic Stretching on the Shear Wave Velocity: the Effects of Hip Adduction and Abduction
- ClinicalTrials.gov ID
- NCT07350434
- Acronym / sponsor ID
- HIPROT / CEP2601
- Conditions
- Stretching, Control Condition
- Keywords
- stretching, stiffness, nerve, muscle, flexibility, hip
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 12 participants (estimated)
- Lead sponsor
- University of BurgundyUniversity, hospital or other
- Study start
- 1 Feb 2026 (actual)
- Primary completion
- 10 Feb 2026 (actual)
- Study completion
- 30 Jun 2026 (estimated)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Neurodynamic mobilization techniques are widely applied in rehabilitation and physiotherapy to enhance the mobility and function of peripheral nerves. Two main approaches are distinguished : Nerve tensioning and nerve flossing. They both involve proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the position that should be used. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography).
Detailed description
Neurodynamic mobilization techniques are frequently applied in rehabilitation settings to enhance the mobility and function of peripheral nerves, particularly in the management of neuropathic pain such as carpal tunnel syndrome, radiculopathies, or sciatica. Two main approaches are distinguished. Nerve tensioning involves maintaining the nerve stretched at the end of the joint range of motion with relatively limited excursion. It is similar to a static stretching intervention but with distal (ankle) and proximal (cervical) tensions. Nerve flossing (also termed gliding or sliders), consists of alternating proximal and distal joint movements to induce greater neural sliding while avoiding excessive tensile stress. Both techniques appear efficient. However, contradictory findings following neurodynamic stretching highlighted the current lack of consensus regarding the angular position that could be used. For instance, hip rotations or hip adduction could impact muscle or nerve tissue changes, particularly in healthy tissues. Moreover, neurodynamic techniques are of interest for patients, it appeared it could also be applied in healthy individuals and more particularly in athletes. Performed in patients, healthy or athletes, no study has compared different hip positions. Accordingly, the primary objective of the present study was to determine the immediate effect of two hip positions (adduction vs. abduction) during neurodynamic flossing techniques on the sciatic nerve and hamstring tissues using the shear wave elastography (SWE, a form of ultrasonography). This method has been shown reliable to provide non-invasive real-time assessments of soft tissues elastic properties.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| No intervention (neutral) | No intervention | –No intervention with measurements in neutral position |
| No intervention (adduction) | No intervention | –No intervention with measurements in adduction position |
| No intervention (abduction) | No intervention | –No intervention with measurements in abduction position |
| Neurodynamic (neutral) | Active comparator | Other: Maximal neurodynamic flossingThe hip was positioned neutral (alignment between the lower limb and the trunk). |
| Neurodynamic (adduction) | Experimental | Other: Maximal neurodynamic flossingThe hip was positioned in adduction and the neurodynamic stretch was applied. |
| Neurodynamic (abduction) | Experimental | Other: Maximal neurodynamic flossingThe hip was positioned in abduction and the neurodynamic stretch was applied. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- healthy
- physical active
- no injuries (lower limb or back pain) in the past 3 months
Key exclusion criteria (2 listed)
- Specific lower limb (hamstring) injuries in the past 2 years
- Not restraining activity 24h before participation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Maximal neurodynamic flossingNeurodynamic flossing was applied at pain threshold on hamstring muscles and repeated 5 times during 60s at the point of pain. During the neurodynamic conditions, head and ankle movement permitted to mobilize nerve tissues. Flossing is the alternation of these movements every 2 seconds. | Other | Neurodynamic (abduction), Neurodynamic (adduction), Neurodynamic (neutral) |
Primary outcome
Nerve shear wave velocity using elastography in neutral position
Time frame: Before the intervention and at the end (immediately after) the intervention
Shear wave velocity of the sciatic nerve will be evaluated by using an ultrasound (echography) device with a specific mode called "shear wave elastography". Briefly, the ultrasound probe will deliver an ultrasound wave. The propagation speed (called '"shear wave velocity") will be measured by the same probe. The greater the velocity is, the harder the tissue is. The hip position was neutral (alignment between the lower limb and the trunk).
10 secondary outcomes
Nerve shear wave velocity using elastography in experimental position
Time frame: Before the intervention and at the end (immediately after) the intervention
Muscle shear wave velocity using elastography in neutral position
Time frame: Before the intervention and at the end (immediately after) the intervention
Muscle shear wave velocity using elastography in the experimental position
Time frame: Before the intervention and at the end (immediately after) the intervention
Hamstring force
Time frame: Before the intervention and at the end (immediately after) the intervention
Biceps femoris electromyographic activity
Time frame: Before the intervention and at the end (immediately after) the intervention
Semitendinosus electromyographic activity
Time frame: Before the intervention and at the end (immediately after) the intervention
passive knee extension
Time frame: Before the intervention and at the end (immediately after) the intervention
Global flexibility
Time frame: Before the intervention and at the end (immediately after) the intervention
Slump test
Time frame: Before the intervention and at the end (immediately after) the intervention
discomfort
Time frame: At the end (immediately after) the intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Apr 2026.
- Individual participant dataSharing planned: Yes. data freely available in online websites
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nicolas Babault principal investigator
universite bourgogne europe
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Maximal neurodynamic flossing in people with Stretching and Control Condition, run by University of Burgundy at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nicolas Babault (+33380396743, nicolas.babault@ube.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nerve shear wave velocity using elastography in neutral position (time frame: Before the intervention and at the end (immediately after) the intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Apr 2026.