AgingNCT07351877
Precision Vibration Therapy for Neuromuscular and Functional Improvement in Older Adults and Stroke Survivors
A study testing Precision Vibration Therapy and Conventional Rehabilitation in people with Aging and Stroke, run by National Health Research Institutes, Taiwan at 1 site in Taiwan.
Trial summary
To address muscle weakness, sensory degradation, functional decline, and pain caused by geriatric syndromes in older adults and stroke survivors, this project proposes a series of studies aimed at improving neuromuscular performance, muscle strength, proprioceptive gain, functional outcomes, and pain relief through… Read more about this study
- Who is it for?
- Ages 18 to 95 years
- What is being tested?
- Precision Vibration Therapy and Conventional Rehabilitation
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteTaiwan
- Study dates
- 18 Sep 2024to 31 Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 95 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Older Adults:
- Meet two or more criteria of the Study of Osteoporotic Fractures (SOF) frailty index
- Willing to participate in the study and comply with all study procedures
- Able to wear and safely use the vibration device
- Normal cognitive function (Mini-Mental State Examination [MMSE] score ≥ 23)
- Presence of knee joint pain in the lower limbs
Show all 14Show fewer
- Stroke Survivors:
- Clinical diagnosis of ischemic or hemorrhagic stroke confirmed by a physician
- Clinically stable stroke condition (i.e., not in an acute or unstable phase)
- Brunnstrom stage ≥ III for the affected limb
- Cognitive ability sufficient to follow study procedures (MMSE score ≥ 23)
- Modified Ashworth Scale (MAS) score < 3 for the paretic limb
- Able to sit safely and participate in vibration or rehabilitation sessions for up to 60 minutes per visit
- Willing and able to comply with all study procedures and provide written informed consent
Who cannot join
- Older Adults:
- Acute or chronic neurological injury involving the upper or lower limbs within the past 6 months
- Acute or chronic musculoskeletal injury involving the upper or lower limbs within the past 6 months
- History of surgery on the upper or lower limbs within the past 6 months
- Stroke Survivors:
- Recurrent stroke during the current episode (i.e., acute re-stroke) or otherwise clinically unstable stroke presentation
Show all 12Show fewer
- Markedly elevated spasticity preventing isolated voluntary movement of the target limb (MAS score ≥ 3)
- Hemianopsia or severe hemineglect that significantly interferes with task execution
- Concomitant vestibular or cerebellar disorders that severely impair motor performance
- Orthopedic or traumatic comorbidities causing significant pain or limiting safe participation during evaluation or intervention
- Cognitive impairment attributable to stroke that precludes effective communication or adherence to the study protocol
- Other neurological or psychiatric disorders judged likely to interfere with motor performance or study outcomes
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
National Center for Geriatrics and Welfare Research, National Health Research Institutes
Taipei
Po-Jung Chen, Ph.D., +886-5-632-5080 ext. 17, pojungchen@nhri.edu.tw
About this study
Official title: Exploring the Clinical Benefits of Precision Vibration on Neuromuscular Induction, Proprioceptive Gain, Functional Enhancement, and Pain Relief in Older Adults and and Stroke Survivors
To address muscle weakness, sensory degradation, functional decline, and pain caused by geriatric syndromes in older adults and stroke survivors, this project proposes a series of studies aimed at improving neuromuscular performance, muscle strength, proprioceptive gain, functional outcomes, and pain relief through the use of a precise vibration system.
In the first phase, a vibration exercise system will be implemented to recruit frail older adults and older adults with stroke for clinical trials. The goal is to verify the benefits of vibration intervention on limb muscle strength, proprioception, and movement function.
In the third phase, quantitative pain assessments and related scales will be used to evaluate chronic pain thresholds and affected regions in older adults and stroke survivors, and to validate the effectiveness of vibration intervention in alleviating their pain.
- Being tested
- Precision Vibration Therapy, Conventional Rehabilitation
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Precision Vibration TherapyDevice
Precision vibration therapy applied to either the upper or lower limb, depending on participant's functional deficit. Each session includes 20 minutes of vibration followed by 40 minutes of conventional rehabilitation (total 60 minutes). The vibration device delivers controlled frequency and amplitude for neuromuscular activation, proprioceptive enhancement, and functional improvement.
Conventional RehabilitationOther
Conventional rehabilitation therapy including task-specific training, strengthening, mobility, and balance exercises. Each session lasts 60 minutes. The therapy protocol is standardized across study sites and matched in duration and therapist contact time to the vibration therapy arms.
| Study group | Role | What they receive |
|---|---|---|
| Older Adults (Conventional Rehabilitation) | Active comparator | Older adults without stroke receive 60 minutes of conventional rehabilitation per session, including individualized strength, mobility, and balance training. Therapy duration is matched to the intervention group. Outcomes assessor is blinded. Receives: Other: Conventional Rehabilitation |
| Older Adults (Vibration Therapy on Upper or Lower Limb) | Experimental | Older adults without stroke receive 20 minutes of precision vibration therapy (applied to the upper or lower limb according to primary deficit) followed by 40 minutes of conventional rehabilitation per session. The total session time equals 60 minutes. Outcomes assessor is blinded. Receives: Device: Precision Vibration Therapy |
| Stroke Survivors (Conventional Rehabilitation) | Active comparator | Stroke survivors (≥18 years) receive 60 minutes of conventional rehabilitation per session, including task-specific training, strengthening, and mobility exercises. Therapy duration is matched to the intervention group. Outcomes assessor is blinded. Receives: Other: Conventional Rehabilitation |
| Stroke Survivors (Vibration Therapy on Upper or Lower Limb) | Experimental | Stroke survivors receive 20 minutes of precision vibration therapy applied to the affected upper or lower limb followed by 40 minutes of conventional rehabilitation per session (total 60 minutes). Intervention aims to improve muscle strength, proprioception, and functional outcomes. Outcomes assessor is blinded. Receives: Device: Precision Vibration Therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fugl-Meyer Assessment (FMA) Score
The Fugl-Meyer Assessment evaluates motor recovery after stroke, including upper and lower extremity motor performance, coordination, and reflex activity. Higher scores indicate better motor function.
Measured: Baseline and Week 8 (end of intervention)
Motor Assessment Scale (MAS) Score
The Motor Assessment Scale measures functional motor performance across multiple daily activities in stroke patients. Higher scores indicate better motor ability.
Measured: Baseline and Week 8 (end of intervention)
Maximal Voluntary Contraction (MVC) Force
Maximal voluntary contraction of major lower-limb muscles will be measured using isometric dynamometry to assess muscle strength changes.
Measured: Baseline and Week 8 (end of intervention)
Muscle Force Stability
Muscle force steadiness during submaximal contraction tasks will be quantified to evaluate neuromuscular control and stability.
Measured: Baseline and Week 8 (end of intervention)
Surface Electromyography (EMG) Activity
Surface EMG recordings from target muscles will be used to analyze muscle activation patterns, coordination, and fatigue characteristics.
Measured: Baseline and Week 8 (end of intervention)
Pain Intensity (Visual Analog Scale, VAS)
Pain intensity will be assessed using the 10-cm Visual Analog Scale (VAS), where higher scores indicate greater pain severity.
Measured: Baseline and Week 8 (end of intervention)
Functional Performance and Quality of Life
Functional ability and perceived quality of life will be assessed using validated scales including the Barthel Index (BI), Instrumental Activities of Daily Living (IADL), and SF-36 Health Survey.
Measured: Baseline and Week 8 (end of intervention)
6-Minute Walk Test (6MWT) Distance
The 6MWT measures functional endurance and walking capacity. Total distance walked in six minutes is recorded; longer distance indicates improved endurance.
Measured: Baseline and Week 8 (end of intervention)
10-Meter Walk Test (10MWT) Speed
The 10MWT assesses gait speed and mobility. Average walking speed (m/s) over a 10-meter distance is calculated, with faster speeds indicating improved functional mobility.
Measured: Baseline and Week 8 (end of intervention)
30-Second Chair Stand Test Performance
The 30-Second Chair Stand Test measures lower-limb strength and endurance by counting the number of full stands completed in 30 seconds. Higher counts indicate better performance.
Measured: Baseline and Week 8 (end of intervention)
Functional Reach Test Distance
The Functional Reach Test assesses dynamic balance by measuring the maximum forward reach distance while maintaining a fixed base of support. Greater reach distance indicates better balance control.
Measured: Baseline and Week 8 (end of intervention)
Secondary outcomes (12)
Minnesota Manual Dexterity Test (MMDT) Performance
The Minnesota Manual Dexterity Test assesses manual dexterity and coordination of the upper limbs. Performance time (seconds) is recorded; shorter completion times indicate better dexterity.
Measured: Baseline and Week 8 (end of intervention)
Joint Proprioception (Active and Passive Position Sense)
Measures active and passive joint position sense at upper and/or lower limb joints using standard proprioceptive testing procedures. Lower error angles indicate improved proprioceptive acuity.
Measured: Baseline and Week 8 (end of intervention)
Coordination Control (Bimanual Grip and Bilateral Ankle Coordination Tests)
Coordination tests include bilateral grip control and bilateral ankle coordination tasks to evaluate interlimb coordination and control precision.
Measured: Baseline and Week 8 (end of intervention)
Barthel Index (BI) Score
The Barthel Index assesses activities of daily living (ADL) independence, including feeding, bathing, dressing, mobility, and toileting. Higher scores indicate greater functional independence.
Measured: Baseline and Week 8 (end of intervention)
Wolf Motor Function Test (WMFT) Score
The WMFT evaluates upper extremity motor function through timed and functional tasks. Lower time scores and higher functional ratings represent better motor performance.
Measured: Baseline and Week 8 (end of intervention)
Berg Balance Scale (BBS) Score
The BBS assesses static and dynamic balance using 14 tasks. Total scores range from 0 to 56, with higher scores representing better balance.
Measured: Baseline and Week 8 (end of intervention)
Timed Up and Go (TUG) Test Performance
The TUG test measures mobility and dynamic balance by recording the time taken to stand from a chair, walk 3 meters, turn, return, and sit. Shorter times indicate improved mobility.
Measured: Baseline and Week 8 (end of intervention)
Function (Spatiotemporal Parameters)
Gait performance parameters (e.g., gait speed, stride length, cadence, and symmetry) will be assessed to evaluate locomotor function improvement.
Measured: Baseline and Week 8 (end of intervention)
Pain-Related Outcomes (BPI, PADT, PDI, NPRS)
Pain characteristics and interference will be assessed using the Brief Pain Inventory (BPI), Pain Assessment and Documentation Tool (PADT), Pain Disability Index (PDI), and Numeric Pain Rating Scale (NPRS).
Measured: Baseline and Week 8 (end of intervention)
WOMAC Osteoarthritis Index
The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) will evaluate pain, stiffness, and physical function related to knee discomfort.
Measured: Baseline and Week 8 (end of intervention)
Quantitative Sensory Testing (QST) Results
Quantitative sensory testing will be used to assess somatosensory function, including pain threshold and sensitivity.
Measured: Baseline and Week 8 (end of intervention)
Quality of Life (QOL and SF-36)
Overall quality of life and health-related well-being will be assessed using the Quality of Life Questionnaire (QOL) and SF-36 Health Survey.
Measured: Baseline and Week 8 (end of intervention)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start18 Sep 2024
- Primary completion18 Dec 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AgingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This project consists of two independent parallel sub-studies targeting different populations: 1. older adults without stroke and 2. stroke survivors (≥18 years, any age). Each sub-study uses a randomized parallel-group design comparing vibration therapy (upper or lower limb) versus conventional rehabilitation. The two populations will not be enrolled concurrently in the same study phase.
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Health Research Institutes, Taiwan
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07351877
- Sponsor's protocol ID
- EC1130707-E
- Status last verified
- Sep 2025
- First submitted
- 29 Dec 2025
- Last updated
- 20 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Exploring the Clinical Benefits of Precision Vibration on Neuromuscular Induction, Proprioceptive Gain, Functional Enhancement, and Pain Relief in Older Adults and and Stroke Survivors
- ClinicalTrials.gov ID
- NCT07351877
- Acronym / sponsor ID
- EC1130707-E
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- National Health Research Institutes, TaiwanUniversity, hospital or other
- Study start
- 18 Sep 2024 (actual)
- Primary completion
- 18 Dec 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To address muscle weakness, sensory degradation, functional decline, and pain caused by geriatric syndromes in older adults and stroke survivors, this project proposes a series of studies aimed at improving neuromuscular performance, muscle strength, proprioceptive gain, functional outcomes, and pain relief through the use of a precise vibration system.
In the first phase, a vibration exercise system will be implemented to recruit frail older adults and older adults with stroke for clinical trials. The goal is to verify the benefits of vibration intervention on limb muscle strength, proprioception, and movement function.
In the third phase, quantitative pain assessments and related scales will be used to evaluate chronic pain thresholds and affected regions in older adults and stroke survivors, and to validate the effectiveness of vibration intervention in alleviating their pain.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 4
- Model description
- This project consists of two independent parallel sub-studies targeting different populations: 1. older adults without stroke and 2. stroke survivors (≥18 years, any age). Each sub-study uses a randomized parallel-group design comparing vibration therapy (upper or lower limb) versus conventional rehabilitation. The two populations will not be enrolled concurrently in the same study phase.
| Arm | Type | Receives |
|---|---|---|
| Older Adults (Conventional Rehabilitation) | Active comparator | Other: Conventional RehabilitationOlder adults without stroke receive 60 minutes of conventional rehabilitation per session, including individualized strength, mobility, and balance training. Therapy duration is matched to the intervention group. Outcomes assessor is blinded. |
| Older Adults (Vibration Therapy on Upper or Lower Limb) | Experimental | Device: Precision Vibration TherapyOlder adults without stroke receive 20 minutes of precision vibration therapy (applied to the upper or lower limb according to primary deficit) followed by 40 minutes of conventional rehabilitation per session. The total session time equals 60 minutes. Outcomes assessor is blinded. |
| Stroke Survivors (Conventional Rehabilitation) | Active comparator | Other: Conventional RehabilitationStroke survivors (≥18 years) receive 60 minutes of conventional rehabilitation per session, including task-specific training, strengthening, and mobility exercises. Therapy duration is matched to the intervention group. Outcomes assessor is blinded. |
| Stroke Survivors (Vibration Therapy on Upper or Lower Limb) | Experimental | Device: Precision Vibration TherapyStroke survivors receive 20 minutes of precision vibration therapy applied to the affected upper or lower limb followed by 40 minutes of conventional rehabilitation per session (total 60 minutes). Intervention aims to improve muscle strength, proprioception, and functional outcomes. Outcomes assessor is blinded. |
Who may qualify
- Ages
- 18 to 95 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (14 listed)
- Meet two or more criteria of the Study of Osteoporotic Fractures (SOF) frailty index
- Willing to participate in the study and comply with all study procedures
- Able to wear and safely use the vibration device
- Normal cognitive function (Mini-Mental State Examination [MMSE] score ≥ 23)
- Presence of knee joint pain in the lower limbs
Key exclusion criteria (12 listed)
- Acute or chronic neurological injury involving the upper or lower limbs within the past 6 months
- Acute or chronic musculoskeletal injury involving the upper or lower limbs within the past 6 months
- History of surgery on the upper or lower limbs within the past 6 months
- Recurrent stroke during the current episode (i.e., acute re-stroke) or otherwise clinically unstable stroke presentation
- Markedly elevated spasticity preventing isolated voluntary movement of the target limb (MAS score ≥ 3)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Precision Vibration TherapyPrecision vibration therapy applied to either the upper or lower limb, depending on participant's functional deficit. Each session includes 20 minutes of vibration followed by 40 minutes of conventional rehabilitation (total 60 minutes). The vibration device delivers controlled frequency and amplitude for neuromuscular activation, proprioceptive enhancement, and functional improvement. | Device | Older Adults (Vibration Therapy on Upper or Lower Limb), Stroke Survivors (Vibration Therapy on Upper or Lower Limb) |
| Conventional RehabilitationConventional rehabilitation therapy including task-specific training, strengthening, mobility, and balance exercises. Each session lasts 60 minutes. The therapy protocol is standardized across study sites and matched in duration and therapist contact time to the vibration therapy arms. | Other | Older Adults (Conventional Rehabilitation), Stroke Survivors (Conventional Rehabilitation) |
Primary outcome
Fugl-Meyer Assessment (FMA) Score
Time frame: Baseline and Week 8 (end of intervention)
The Fugl-Meyer Assessment evaluates motor recovery after stroke, including upper and lower extremity motor performance, coordination, and reflex activity. Higher scores indicate better motor function.
Motor Assessment Scale (MAS) Score
Time frame: Baseline and Week 8 (end of intervention)
The Motor Assessment Scale measures functional motor performance across multiple daily activities in stroke patients. Higher scores indicate better motor ability.
Maximal Voluntary Contraction (MVC) Force
Time frame: Baseline and Week 8 (end of intervention)
Maximal voluntary contraction of major lower-limb muscles will be measured using isometric dynamometry to assess muscle strength changes.
Muscle Force Stability
Time frame: Baseline and Week 8 (end of intervention)
Muscle force steadiness during submaximal contraction tasks will be quantified to evaluate neuromuscular control and stability.
Surface Electromyography (EMG) Activity
Time frame: Baseline and Week 8 (end of intervention)
Surface EMG recordings from target muscles will be used to analyze muscle activation patterns, coordination, and fatigue characteristics.
Pain Intensity (Visual Analog Scale, VAS)
Time frame: Baseline and Week 8 (end of intervention)
Pain intensity will be assessed using the 10-cm Visual Analog Scale (VAS), where higher scores indicate greater pain severity.
Functional Performance and Quality of Life
Time frame: Baseline and Week 8 (end of intervention)
Functional ability and perceived quality of life will be assessed using validated scales including the Barthel Index (BI), Instrumental Activities of Daily Living (IADL), and SF-36 Health Survey.
6-Minute Walk Test (6MWT) Distance
Time frame: Baseline and Week 8 (end of intervention)
The 6MWT measures functional endurance and walking capacity. Total distance walked in six minutes is recorded; longer distance indicates improved endurance.
10-Meter Walk Test (10MWT) Speed
Time frame: Baseline and Week 8 (end of intervention)
The 10MWT assesses gait speed and mobility. Average walking speed (m/s) over a 10-meter distance is calculated, with faster speeds indicating improved functional mobility.
30-Second Chair Stand Test Performance
Time frame: Baseline and Week 8 (end of intervention)
The 30-Second Chair Stand Test measures lower-limb strength and endurance by counting the number of full stands completed in 30 seconds. Higher counts indicate better performance.
Functional Reach Test Distance
Time frame: Baseline and Week 8 (end of intervention)
The Functional Reach Test assesses dynamic balance by measuring the maximum forward reach distance while maintaining a fixed base of support. Greater reach distance indicates better balance control.
12 secondary outcomes
Minnesota Manual Dexterity Test (MMDT) Performance
Time frame: Baseline and Week 8 (end of intervention)
Joint Proprioception (Active and Passive Position Sense)
Time frame: Baseline and Week 8 (end of intervention)
Coordination Control (Bimanual Grip and Bilateral Ankle Coordination Tests)
Time frame: Baseline and Week 8 (end of intervention)
Barthel Index (BI) Score
Time frame: Baseline and Week 8 (end of intervention)
Wolf Motor Function Test (WMFT) Score
Time frame: Baseline and Week 8 (end of intervention)
Berg Balance Scale (BBS) Score
Time frame: Baseline and Week 8 (end of intervention)
Timed Up and Go (TUG) Test Performance
Time frame: Baseline and Week 8 (end of intervention)
Function (Spatiotemporal Parameters)
Time frame: Baseline and Week 8 (end of intervention)
Pain-Related Outcomes (BPI, PADT, PDI, NPRS)
Time frame: Baseline and Week 8 (end of intervention)
WOMAC Osteoarthritis Index
Time frame: Baseline and Week 8 (end of intervention)
Quantitative Sensory Testing (QST) Results
Time frame: Baseline and Week 8 (end of intervention)
Quality of Life (QOL and SF-36)
Time frame: Baseline and Week 8 (end of intervention)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Precision Vibration Therapy and Conventional Rehabilitation in people with Aging and Stroke, run by National Health Research Institutes, Taiwan at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 14 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 20 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Po-Jung Chen, Ph.D. (+886-5-632-5080 ext. 17, pojungchen@nhri.edu.tw), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fugl-Meyer Assessment (FMA) Score (time frame: Baseline and Week 8 (end of intervention)). The study lists 11 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Jan 2026.