Postoperative Pain ManagementUS-LTAPNCT07352189
Ultrasound-Guided Versus Laparoscopy-Guided Transversus Abdominis Plane Block for Postoperative Analgesia
A study testing Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block and Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block in people with Postoperative Pain Management, run by Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Postoperative Pain Management
- What is being tested?
- Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block and Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 11 Jan 2023to 15 Jun 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients aged 18-70 yeras
- ASA physical status I-III
- Scheduled for laparoscopic upper abdominal surgery
- Provided written informed consent
Who cannot join
- Patient refusal
- Allergy to local anesthetics
- Coagulopathy
- Infection at the injection site
- Severe systemic disease
- ASA physical status IV-V
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Maltepe University Faculty of Medicine Hospital
Istanbul, Istanbul, 34000
About this study
Official title: Comparison of the Efficacy of Ultrasound-Guided and Laparoscopy-Guided Transversus Abdominis Plane(TAP) Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Upper Abdominal Surgery
This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Postoperative pain scores, analgesic consumption and recovery parameters were evaluated during the first 24 hours after surgery.
Read the detailed description
Patients aged 18-70 years with ASA physical status I-III who were scheduled for laparoscopic upper abdominal surgery under general anesthesia were included in the study. After induction of anesthesia, patients were randomly assigned to one of two group, bilateral subcostal transversus abdominis plane block was performed under ultrasound-guidance using a local anesthetic mixture before extubation. In the laparoscopy-guided group, bilateral subcostal transversus abdominis plane block was performed under laparoscopic guidance using the same local anesthetic mixture before abdominal closure. Postoperative pain intensity was assessed by using the Numeric Rating Scale (NRS). Total opioid consumption, time to first analgesic requirement, paracetamol consumption, postoperative nausea and vomiting, length of hospital stay, time to ambulation and time to gastrointestinal recovery were recorded during the first 24 hours after surgery. Complications related to the TAP block were also evaluated.
- Conditions
- Postoperative Pain Management
- Being tested
- Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block, Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block
- Keywords
- Transversus Abdominis Plane Block, TAP block, Postoperative Pain, analgesia
- Medical subject headings
- Pain, Postoperative, Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound-guided Transversus Abdominis Plane (US-TAP) BlockProcedure or surgery
Bilateral ultrasound-guided subcostal transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL0.25% bupivacaine and 10 ml of 1% lidocaine).
Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) BlockProcedure or surgery
Bilateral laparoscopy-guided transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL 0.25% bupivacaine and 10 ml of 1% lidocaine).
| Study group | Role | What they receive |
|---|---|---|
| Ultrasound-guided TAP block (Group U) | Experimental | Patients receiving ultrasound-guided subcostal transversus abdominis plane block for postoperative analgesia. Receives: Procedure: Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block |
| Laparoscopy-guided TAP block (Group L) | Experimental | Patients receiving laparoscopy-guided transversus abdominis plane block for postoperative analgesia. Receives: Procedure: Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pain score (NRS)
Postoperative pain intensity measured using the Numeric Rating Scale (NRS), a 0-10 scale where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicates worse pain.
Measured: First 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start11 Jan 2023
- Primary completion15 Jun 2023
- Study completion15 Jun 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative Pain ManagementStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Maltepe University
- Responsible party
- Sponsor
- Investigators
- Talat Ercan E Şerifsoy, MD, Principal investigator, Maltepe University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07352189
- Sponsor's protocol ID
- MALTEPE-2022-965164
- Acronym
- US-LTAP
- Status last verified
- Jan 2026
- First submitted
- 11 Jan 2026
- Last updated
- 21 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Efficacy of Ultrasound-Guided and Laparoscopy-Guided Transversus Abdominis Plane(TAP) Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Upper Abdominal Surgery
- ClinicalTrials.gov ID
- NCT07352189
- Acronym / sponsor ID
- US-LTAP / MALTEPE-2022-965164
- Conditions
- Postoperative Pain Management
- Keywords
- Transversus Abdominis Plane Block, TAP block, Postoperative Pain, analgesia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research HospitalUniversity, hospital or other
- Collaborators
- Maltepe University
- Study start
- 11 Jan 2023 (actual)
- Primary completion
- 15 Jun 2023 (actual)
- Study completion
- 15 Jun 2023 (actual)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Postoperative pain scores, analgesic consumption and recovery parameters were evaluated during the first 24 hours after surgery.
Detailed description
Patients aged 18-70 years with ASA physical status I-III who were scheduled for laparoscopic upper abdominal surgery under general anesthesia were included in the study. After induction of anesthesia, patients were randomly assigned to one of two group, bilateral subcostal transversus abdominis plane block was performed under ultrasound-guidance using a local anesthetic mixture before extubation. In the laparoscopy-guided group, bilateral subcostal transversus abdominis plane block was performed under laparoscopic guidance using the same local anesthetic mixture before abdominal closure. Postoperative pain intensity was assessed by using the Numeric Rating Scale (NRS). Total opioid consumption, time to first analgesic requirement, paracetamol consumption, postoperative nausea and vomiting, length of hospital stay, time to ambulation and time to gastrointestinal recovery were recorded during the first 24 hours after surgery. Complications related to the TAP block were also evaluated.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ultrasound-guided TAP block (Group U) | Experimental | Procedure: Ultrasound-guided Transversus Abdominis Plane (US-TAP) BlockPatients receiving ultrasound-guided subcostal transversus abdominis plane block for postoperative analgesia. |
| Laparoscopy-guided TAP block (Group L) | Experimental | Procedure: Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) BlockPatients receiving laparoscopy-guided transversus abdominis plane block for postoperative analgesia. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients aged 18-70 yeras
- ASA physical status I-III
- Scheduled for laparoscopic upper abdominal surgery
- Provided written informed consent
Key exclusion criteria (6 listed)
- Patient refusal
- Allergy to local anesthetics
- Coagulopathy
- Infection at the injection site
- Severe systemic disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound-guided Transversus Abdominis Plane (US-TAP) BlockBilateral ultrasound-guided subcostal transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL0.25% bupivacaine and 10 ml of 1% lidocaine). | Procedure or surgery | Ultrasound-guided TAP block (Group U) |
| Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) BlockBilateral laparoscopy-guided transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL 0.25% bupivacaine and 10 ml of 1% lidocaine). | Procedure or surgery | Laparoscopy-guided TAP block (Group L) |
Primary outcome
Postoperative pain score (NRS)
Time frame: First 24 hours postoperatively
Postoperative pain intensity measured using the Numeric Rating Scale (NRS), a 0-10 scale where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicates worse pain.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Talat Ercan E Şerifsoy, MD principal investigator
Maltepe University Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block and Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block in people with Postoperative Pain Management, run by Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative pain score (NRS) (time frame: First 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jan 2026.