Dental AnxietyNCT07352397
Inhaled Lavender Oil, Rosemary Oil, and Their Combination in Reducing Dental Anxiety and Pain in Pediatric Dental Patients
A study testing Lavender group, Rosemary group and Combination of both lavender and rosemary in people with Dental Anxiety, run by Alexandria University at 1 site in Egypt.
Trial summary
Background: Dental anxiety and pain are common concerns in pediatric dentistry. These issues can lead to negative experiences for children and can make it difficult for them to cooperate during treatment. While medications can help manage these symptoms, it can also have side effects. Read more about this study
- Who is it for?
- Ages 6 to 9 years
- Conditions the study is for
- Dental Anxiety
- What is being tested?
- Lavender group, Rosemary group and Combination of both lavender and rosemary
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteEgypt
- Study dates
- 20 Jan 2026to 25 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 9 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Frankl behavioural rating score 2 or 3 during preoperative assessment.
- Healthy children ASAI.
- Children without a previous dental history.
- Children presenting with at least one mandibular molar indicated for extraction. (43)
- Completion of the written informed consent form by parents/guardian.
Who cannot join
- Children with colds, asthma, and any other respiratory diseases.
- Children who took NSAIDs or analgesic drugs in the last 8 hours before treatment.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Alexandria Faculty of Dentistry
Alexandria
Mayy Sharaf, BDS, Mayysaleh95@gmail.com
Mayysaleh95@gmail.com
About this study
Official title: The Effect of Inhaled Lavender Oil, Rosemary Oil, and Their Combination in Reducing Dental Anxiety and Pain in Pediatric Dental Patients (A Randomized Controlled Clinical Trial)
Background: Dental anxiety and pain are common concerns in pediatric dentistry. These issues can lead to negative experiences for children and can make it difficult for them to cooperate during treatment. While medications can help manage these symptoms, it can also have side effects. This highlights the need for safe and effective complementary treatments. Aromatherapy, particularly with lavender and rosemary oils, has demonstrated anxiolytic and analgesic properties in different fields. However, their effect in helping children cope with dental anxiety and pain during procedures requiring local anesthesia has not yet been thoroughly studied.
Purpose: This study aims to investigate the efficacy of inhaled lavender oil, rosemary oil, and their combination in reducing dental anxiety and pain in children receiving local anesthesia for extraction of lower primary molar
- Conditions
- Dental Anxiety
- Being tested
- Lavender group, Rosemary group, Combination of both lavender and rosemary, No essential oils
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Lavender groupOther
Children in this group will be inhaled 0.5 ml of prepared mixture (of Lavandula Angustifolia+ Sweet Almond carrier oil ) on a cotton pad attached to the facial steamer .
Rosemary groupOther
Children in this group will be inhaled 0.5 ml of prepared mixture (of Rosmarinus Officinalis + Sweet Almond carrier oil ) on a cotton pad attached to the facial steamer
Combination of both lavender and rosemaryOther
Children in this group would be inhaled 0.5 ml of prepared mixture (of Lavandula Angustifolia and Rosmarinus Officinalis + Sweet Almond carrier oil) on a cotton pad attached to the facial steamer .
No essential oilsOther
Children in this group will be inhaled 0.5 mL of the carrier oil (Sweet Almond ) on a cotton pad attached to the facial steamer .
| Study group | Role | What they receive |
|---|---|---|
| Group I | Experimental | Not described Receives: Other: Lavender group |
| Group II | Experimental | Not described Receives: Other: Rosemary group |
| Group III | Experimental | Not described Receives: Other: Combination of both lavender and rosemary |
| Group IV | Active comparator | Not described Receives: Other: No essential oils |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in anxiety scores
Venham scale will be used. it ranges from 0 (relaxed) to 5 (Child out of contact with the relaity of threat)
Measured: up to 1 week
Secondary outcomes (3)
Change in anxiety scores (by children)
Comprises a row of five faces ranging from very happy (score 1) to very unhappy (score 5)
Measured: up to 1 week
Change in pain scores
FLACC scale. It is an objectively pain assessment Scale .The scale quantifies pain by observing five distinct behavioral categories: face, legs, activity, cry, and consolability. Each category is assigned a score from 0 to 2, which are then summed to yield a total pain score ranging from 0 to 10.
Measured: up to 1 week
Change in heart rate
it will be used by pulse oximeter.
Measured: During procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start20 Jan 2026 (estimated)
- Primary completion25 Feb 2026 (estimated)
- Study completion25 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental AnxietyStudies of the same condition, open and under way.
- More trials run by Alexandria UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Alexandria University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07352397
- Sponsor's protocol ID
- 1188-11/2025
- Status last verified
- Jan 2026
- First submitted
- 12 Jan 2026
- Last updated
- 20 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Inhaled Lavender Oil, Rosemary Oil, and Their Combination in Reducing Dental Anxiety and Pain in Pediatric Dental Patients (A Randomized Controlled Clinical Trial)
- ClinicalTrials.gov ID
- NCT07352397
- Acronym / sponsor ID
- 1188-11/2025
- Conditions
- Dental Anxiety
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Alexandria UniversityUniversity, hospital or other
- Study start
- 20 Jan 2026 (estimated)
- Primary completion
- 25 Feb 2026 (estimated)
- Study completion
- 25 Feb 2026 (estimated)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: Dental anxiety and pain are common concerns in pediatric dentistry. These issues can lead to negative experiences for children and can make it difficult for them to cooperate during treatment. While medications can help manage these symptoms, it can also have side effects. This highlights the need for safe and effective complementary treatments. Aromatherapy, particularly with lavender and rosemary oils, has demonstrated anxiolytic and analgesic properties in different fields. However, their effect in helping children cope with dental anxiety and pain during procedures requiring local anesthesia has not yet been thoroughly studied.
Purpose: This study aims to investigate the efficacy of inhaled lavender oil, rosemary oil, and their combination in reducing dental anxiety and pain in children receiving local anesthesia for extraction of lower primary molar
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Group I | Experimental | Other: Lavender group |
| Group II | Experimental | Other: Rosemary group |
| Group III | Experimental | Other: Combination of both lavender and rosemary |
| Group IV | Active comparator | Other: No essential oils |
Who may qualify
- Ages
- 6 to 9 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (5 listed)
- Frankl behavioural rating score 2 or 3 during preoperative assessment.
- Healthy children ASAI.
- Children without a previous dental history.
- Children presenting with at least one mandibular molar indicated for extraction. (43)
- Completion of the written informed consent form by parents/guardian.
Key exclusion criteria (2 listed)
- Children with colds, asthma, and any other respiratory diseases.
- Children who took NSAIDs or analgesic drugs in the last 8 hours before treatment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Lavender groupChildren in this group will be inhaled 0.5 ml of prepared mixture (of Lavandula Angustifolia+ Sweet Almond carrier oil ) on a cotton pad attached to the facial steamer . | Other | Group I |
| Rosemary groupChildren in this group will be inhaled 0.5 ml of prepared mixture (of Rosmarinus Officinalis + Sweet Almond carrier oil ) on a cotton pad attached to the facial steamer | Other | Group II |
| Combination of both lavender and rosemaryChildren in this group would be inhaled 0.5 ml of prepared mixture (of Lavandula Angustifolia and Rosmarinus Officinalis + Sweet Almond carrier oil) on a cotton pad attached to the facial steamer . | Other | Group III |
| No essential oilsChildren in this group will be inhaled 0.5 mL of the carrier oil (Sweet Almond ) on a cotton pad attached to the facial steamer . | Other | Group IV |
Primary outcome
Change in anxiety scores
Time frame: up to 1 week
Venham scale will be used. it ranges from 0 (relaxed) to 5 (Child out of contact with the relaity of threat)
3 secondary outcomes
Change in anxiety scores (by children)
Time frame: up to 1 week
Change in pain scores
Time frame: up to 1 week
Change in heart rate
Time frame: During procedure
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Lavender group, Rosemary group and Combination of both lavender and rosemary in people with Dental Anxiety, run by Alexandria University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 20 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mayy Sharaf, BDS (01555384075, Mayysaleh95@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in anxiety scores (time frame: up to 1 week). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Jan 2026.