CancerNCT07352579
From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care
An observational study of Cancer, run by Thomas Jefferson University at 1 site in United States.
Trial summary
This observational study aims to identify the factors that influence whether cancer patients accept or decline supportive care services after screening positive for health-related social needs (HRSNs) at the Sidney Kimmel Comprehensive Cancer Center. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Cancer
- What is being tested?
- Survey and Interview
- How many people
- 55 participants
- Where
- 1 siteUnited States
- Study dates
- 11 Dec 2025to 18 Sep 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adult cancer patients who received care at SKCCC who were engaged in HRSN screening
Who may be able to join
- Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:
- Provide informed consent via check box for survey
- Provide verbal consent via Zoom for interview
- Must be able to read and understand English
- Willing to comply with all study procedures and be available for the duration of the study
- Patients with existing HRSN data in their EHR that answere4d yes to risk in at least one domain and no to wanting help/follow up
Who cannot join
- An individual who meets any of the following criteria will be excluded from participation in this study:
- If they do not consent
- Non-patients with existing HRSN data in their EHR
- Individuals unable to complete the survey due to language barriers or other cognitive limitations
Trial locations and contacts
1 site in 1 country.
United States1 site
Sidney Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, Pennsylvania, 19107
About this study
This observational study aims to identify the factors that influence whether cancer patients accept or decline supportive care services after screening positive for health-related social needs (HRSNs) at the Sidney Kimmel Comprehensive Cancer Center.
The study focuses on adult oncology patients who previously reported at least one HRSN-such as transportation, food, housing, or utility needs-but declined assistance when it was offered.
Read more
The main questions it aims to answer are:
- What factors shape cancer patients' intentions to use supportive care services for HRSNs?
- Why do patients who screen positive for HRSNs choose not to accept help offered by the healthcare system?
Participants will:
- Complete a one-time electronic survey delivered via MyChart or email.
- Optionally participate in a semi-structured Zoom interview (for a subset of 20-30 survey respondents) to explore decision-making in greater depth.
Read the detailed description
This is a cross-sectional observational study. There will be 500 participants for MyChart survey and 20 participants for semi-structured interviews. Surveys will be distributed via MyChart and email and will take about 10 minutes to complete. The main purpose of this study is to understand why SKCCC participants are not seeking support for their corresponding HRSNs from the healthcare system. The hypothesis is that a range of factors are contributing to SKCCC patients' decline of resources to address risks identified in HRSN screening potentially inclusive of mistrust of healthcare systems, perception that there are no resources to help, feelings others can use the resources more than themselves, as well as protective factors like past resiliency and resourcefulness. An examination of the initial HRSN screening data for cancer patients within this health system revealed that, in 2024, 5,727 (74.7%; n=7662) patients who were in active cancer treatment completed the HRSN screening questionnaire in four domains: transportation access, food insecurity, housing instability, and utility needs. Of these, 716 patients (12.5%) reported having a need in at least one HRSN domain. However, only 343 patients (47.9%, n = 716) wanted help from the healthcare system to address their HRSN(s). This highlights that the majority (52.1%, n = 716) of cancer patients in active treatment who have been screened for HRSN have unmet needs that could be addressed but are not being flagged as such in our healthcare system. This preliminary data sheds light on the concrete and resource needs of cancer patients, but there is not a good understanding of why participants are not seeking support for their corresponding HRSNs from the healthcare system.
- Conditions
- Cancer
- Being tested
- Survey, Interview
- Keywords
- Health-Related Social Needs, HRSNs, transportation access, food insecurity, housing instability, utility needs, Survey, Interview
- Medical subject headings
- Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
SurveyOther
Participants complete a one-time electronic survey to assess factors influencing the decision to decline assistance for identified Health-Related Social Needs (HRSNs). The survey includes questions related to transportation access, food insecurity, housing instability, and utility needs. Survey completion takes approximately 10 minutes.
InterviewOther
Interviews will be semi-structured and will be offered to 20 participants who have completed the survey and meet eligibility criteria. Interviews will be conducted via a Zoom. Zoom will create a transcription of the interview which will be saved in a secure encrypted space, no video will be saved.
| Study group | Role | What they receive |
|---|---|---|
| Cancer Patients Screened for Health-Related Social Needs (HRSNs) | This group includes adult cancer patients receiving care at Sidney Kimmel Comprehensive Cancer Center (SKCCC) who previously completed a Health-Related Social Needs (HRSNs) screening in the electronic health record. This will be achieved by providing patients with a one-time survey. The surveys will be distributed via MyChart messages and emails. Additionally, 20 patients who complete the survey will be asked to complete a short interview to further understand why cancer patients identified as high-risk for HRSNs decline connections to care and intervention-ultimately to gain an understanding into the factors that they take into account when determining whether they want to be connected to a resource or service connection related to HRSNs. Receives: Other: Survey; Other: Interview |
What is being measured
The primary outcome is the main question the study is designed to answer.
Factors influencing cancer patients' intent to use oncology supportive care for HRSNs
Measured via Surveys (self-reported) using a structured questionnaires with binary (Yes/No) responses and Likert Style questions (Quality of Life and FACT-ES).
Measured: approximately 4 months
Secondary outcomes (1)
Factors associated with declining HSRN-related supportive care services
Interviews will be semi-structured and will be offered to 20 participants who have completed the survey and meet eligibility criteria.
Measured: approximately 4 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start11 Dec 2025
- Primary completion18 Sep 2026
- Study completion18 Sep 2026
Why it stopped: Slow Recruitment/PI departure
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CancerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 55 participants (actual)
Sponsor and investigators
- Lead sponsor
- Thomas Jefferson University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Munjireen Sifat, PhD, MPH, Principal investigator, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07352579
- Sponsor's protocol ID
- iRISID-2025-1005
- Other IDs
- JT 46229
- Status last verified
- Oct 2026
- First submitted
- 9 Jan 2026
- Last updated
- 29 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- From Screening to Support: A Multi-Method Analysis of HRSN Integration in Cancer Care
- ClinicalTrials.gov ID
- NCT07352579
- Acronym / sponsor ID
- iRISID-2025-1005
- Conditions
- Cancer
- Keywords
- Health-Related Social Needs, HRSNs, transportation access, food insecurity, housing instability, utility needs, Survey, Interview
- Study type
- Observational
- Recruitment status
- TerminatedReason stopped: Slow Recruitment/PI departure
- Enrolment
- 55 participants (actual)
- Lead sponsor
- Thomas Jefferson UniversityUniversity, hospital or other
- Study start
- 11 Dec 2025 (actual)
- Primary completion
- 18 Sep 2026 (actual)
- Study completion
- 18 Sep 2026 (actual)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study aims to identify the factors that influence whether cancer patients accept or decline supportive care services after screening positive for health-related social needs (HRSNs) at the Sidney Kimmel Comprehensive Cancer Center.
The study focuses on adult oncology patients who previously reported at least one HRSN-such as transportation, food, housing, or utility needs-but declined assistance when it was offered.
The main questions it aims to answer are:
- What factors shape cancer patients' intentions to use supportive care services for HRSNs?
- Why do patients who screen positive for HRSNs choose not to accept help offered by the healthcare system?
Participants will:
- Complete a one-time electronic survey delivered via MyChart or email.
- Optionally participate in a semi-structured Zoom interview (for a subset of 20-30 survey respondents) to explore decision-making in greater depth.
Detailed description
This is a cross-sectional observational study. There will be 500 participants for MyChart survey and 20 participants for semi-structured interviews. Surveys will be distributed via MyChart and email and will take about 10 minutes to complete. The main purpose of this study is to understand why SKCCC participants are not seeking support for their corresponding HRSNs from the healthcare system. The hypothesis is that a range of factors are contributing to SKCCC patients' decline of resources to address risks identified in HRSN screening potentially inclusive of mistrust of healthcare systems, perception that there are no resources to help, feelings others can use the resources more than themselves, as well as protective factors like past resiliency and resourcefulness. An examination of the initial HRSN screening data for cancer patients within this health system revealed that, in 2024, 5,727 (74.7%; n=7662) patients who were in active cancer treatment completed the HRSN screening questionnaire in four domains: transportation access, food insecurity, housing instability, and utility needs. Of these, 716 patients (12.5%) reported having a need in at least one HRSN domain. However, only 343 patients (47.9%, n = 716) wanted help from the healthcare system to address their HRSN(s). This highlights that the majority (52.1%, n = 716) of cancer patients in active treatment who have been screened for HRSN have unmet needs that could be addressed but are not being flagged as such in our healthcare system. This preliminary data sheds light on the concrete and resource needs of cancer patients, but there is not a good understanding of why participants are not seeking support for their corresponding HRSNs from the healthcare system.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Cancer Patients Screened for Health-Related Social Needs (HRSNs) | – | Other: Survey, Other: InterviewThis group includes adult cancer patients receiving care at Sidney Kimmel Comprehensive Cancer Center (SKCCC) who previously completed a Health-Related Social Needs (HRSNs) screening in the electronic health record. This will be achieved by providing patients with a one-time survey. The surveys will be distributed via MyChart messages and emails. Additionally, 20 patients who complete the survey will be asked to complete a short interview to further understand why cancer patients identified as high-risk for HRSNs decline connections to care and intervention-ultimately to gain an understanding into the factors that they take into account when determining whether they want to be connected to a resource or service connection related to HRSNs. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adult cancer patients who received care at SKCCC who were engaged in HRSN screening
Key inclusion criteria (6 listed)
- Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:
Key exclusion criteria (4 listed)
- An individual who meets any of the following criteria will be excluded from participation in this study:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| SurveyParticipants complete a one-time electronic survey to assess factors influencing the decision to decline assistance for identified Health-Related Social Needs (HRSNs). The survey includes questions related to transportation access, food insecurity, housing instability, and utility needs. Survey completion takes approximately 10 minutes. | Other | Cancer Patients Screened for Health-Related Social Needs (HRSNs) |
| InterviewInterviews will be semi-structured and will be offered to 20 participants who have completed the survey and meet eligibility criteria. Interviews will be conducted via a Zoom. Zoom will create a transcription of the interview which will be saved in a secure encrypted space, no video will be saved. | Other | Cancer Patients Screened for Health-Related Social Needs (HRSNs) |
Primary outcome
Factors influencing cancer patients' intent to use oncology supportive care for HRSNs
Time frame: approximately 4 months
Measured via Surveys (self-reported) using a structured questionnaires with binary (Yes/No) responses and Likert Style questions (Quality of Life and FACT-ES).
1 secondary outcome
Factors associated with declining HSRN-related supportive care services
Time frame: approximately 4 months
Results and safety
The study was stopped early (reason given: Slow Recruitment/PI departure). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Oct 2026.
Related trials for Cancer
Not yet recruitingPhase 1/2
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
Thyroid Cancer
RecruitingPhase 1/2
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma
RecruitingPhase 3
A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)
Ovarian Cancer, Ovarian Neoplasms
RecruitingPhase 1/2
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma
Lymphoma, Non-Hodgkin Lymphoma
RecruitingPhase 3
Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia (APL), Acute Promyelocytic Leukaemia
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Munjireen Sifat, PhD, MPH principal investigator
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cancer, run by Thomas Jefferson University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 29 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: Slow Recruitment/PI departure). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Factors influencing cancer patients' intent to use oncology supportive care for HRSNs (time frame: approximately 4 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Oct 2026.