Pain Management After SurgeryNCT07352683
Open TAP-block in Pediatric Abdominal Surgery
A study testing TAP-block and Wound catheter in people with Pain Management After Surgery, run by Uppsala University at 1 site in Sweden.
Trial summary
The goal of this trial is to evaluate an open TAP-block vs continuous administration of local anestetic via a wound catheter for postoperative pain management in patients 1-15 years of age undergoing open abdominal surgery. Read more about this study
- Who is it for?
- Ages 1 year to 15 years
- Conditions the study is for
- Pain Management After Surgery
- What is being tested?
- TAP-block and Wound catheter
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 88 participants
- Where
- 1 siteSweden
- Study dates
- 1 Dec 2025to 1 Jan 2030
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 year to 15 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Age 1-15 years
- Scheduled for elective or acute open adominal surgical procedure
Who cannot join
- chronic abdominal pain
- known allergy to local analgetic
- Stage 4 renal failure
- psychiatric ailnment
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Sweden1 site, 1 recruiting
- Recruiting
Akademiska sjukhuset
Uppsala, 75123
Sofia Arwhed, MD, PhD, sofia.arwehed@regionuppsala.se
About this study
Official title: TAP-blockad Vid öppen Bukkirurgi Hos Barn
The goal of this trial is to evaluate an open TAP-block vs continuous administration of local anestetic via a wound catheter for postoperative pain management in patients 1-15 years of age undergoing open abdominal surgery.
- Conditions
- Pain Management After Surgery
- Being tested
- TAP-block, Wound catheter
- Keywords
- pediatric, TAP-block, postoperative pain management
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
TAP-blockProcedure or surgery
Open TAP(transverse abdominal plane)-block placed by the surgeon using open technique at end of surgery before wound closure
Wound catheterProcedure or surgery
A catheter placed subcutainiousley for the continuous administration of local anestethic in the wound for up to 3 days post-op
| Study group | Role | What they receive |
|---|---|---|
| TAP-block | Experimental | Subjects in the TAP-block arm will recieve an open TAP-block at the end of the procedure vbefore wound closure Receives: Procedure: TAP-block |
| Wound infiltration | Active comparator | Subjects in the wound infiltration group will recieve contionious administration of local anastethic via a wound catheter placed subcutaneousley during wound closure. Receives: Procedure: Wound catheter |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative opiates
Amount of postoperative opiates administered
Measured: during the first 24 hours following surgery and total opioids until discarge up to 14 days postoperative
Secondary outcomes (2)
Lenght of stay
Duration of hospital stay
Measured: Days from surgery through study completeion, an average expected time of7 days
Pain assessment
Pain assesment using validated instruments, FLACC or FPS-R
Measured: End of surgery until 24 hours post-op
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start1 Dec 2025
- Primary completion1 Jan 2030 (estimated)
- Study completion1 Jan 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pain Management After SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 88 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Uppsala University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Oskar Nensén, MD, PhD, Principal investigator, Uppsala University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07352683
- Sponsor's protocol ID
- NOR001
- Status last verified
- Jan 2026
- First submitted
- 2 Dec 2025
- Last updated
- 20 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: IPD (anonymized) underlying data in a future publication will be made available on request.
Study at a glance
From the registry record, last updated by the sponsor on 20 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- TAP-blockad Vid öppen Bukkirurgi Hos Barn
- ClinicalTrials.gov ID
- NCT07352683
- Acronym / sponsor ID
- NOR001
- Conditions
- Pain Management After Surgery
- Keywords
- pediatric, TAP-block, postoperative pain management
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 88 participants (estimated)
- Lead sponsor
- Uppsala UniversityUniversity, hospital or other
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- 1 Jan 2030 (estimated)
- Study completion
- 1 Jan 2030 (estimated)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this trial is to evaluate an open TAP-block vs continuous administration of local anestetic via a wound catheter for postoperative pain management in patients 1-15 years of age undergoing open abdominal surgery.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| TAP-block | Experimental | Procedure: TAP-blockSubjects in the TAP-block arm will recieve an open TAP-block at the end of the procedure vbefore wound closure |
| Wound infiltration | Active comparator | Procedure: Wound catheterSubjects in the wound infiltration group will recieve contionious administration of local anastethic via a wound catheter placed subcutaneousley during wound closure. |
Who may qualify
- Ages
- 1 year to 15 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (2 listed)
- Age 1-15 years
- Scheduled for elective or acute open adominal surgical procedure
Key exclusion criteria (4 listed)
- chronic abdominal pain
- known allergy to local analgetic
- Stage 4 renal failure
- psychiatric ailnment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| TAP-blockOpen TAP(transverse abdominal plane)-block placed by the surgeon using open technique at end of surgery before wound closure | Procedure or surgery | TAP-block |
| Wound catheterA catheter placed subcutainiousley for the continuous administration of local anestethic in the wound for up to 3 days post-op | Procedure or surgery | Wound infiltration |
Primary outcome
Postoperative opiates
Time frame: during the first 24 hours following surgery and total opioids until discarge up to 14 days postoperative
Amount of postoperative opiates administered
2 secondary outcomes
Lenght of stay
Time frame: Days from surgery through study completeion, an average expected time of7 days
Pain assessment
Time frame: End of surgery until 24 hours post-op
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Jan 2026.
- Individual participant dataSharing planned: Yes. IPD (anonymized) underlying data in a future publication will be made available on request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Oskar Nensén, MD, PhD principal investigator
Uppsala University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing TAP-block and Wound catheter in people with Pain Management After Surgery, run by Uppsala University at 1 site in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 20 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Oskar Nensén, MD, PhD (+46186110000, oskar.nensen@uu.se), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative opiates (time frame: during the first 24 hours following surgery and total opioids until discarge up to 14 days postoperative). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Jan 2026.