Upper Extremity SurgeryNCT07352839
Brachial Plexus Block vs General Anesthesia in Upper Extremity Surgery
A study testing Brachial Plexus Block and General Anesthesia in people with Upper Extremity Surgery and Regional Anesthesia, run by Adana City Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This study compares two different anesthesia methods for upper arm and hand surgery: regional anesthesia (brachial plexus block) versus general anesthesia. Regional anesthesia numbs only the arm being operated on by injecting local anesthetic near the nerves, while the patient remains awake or lightly sedated. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Upper Extremity Surgery, Regional Anesthesia, General Anesthetic
- What is being tested?
- Brachial Plexus Block and General Anesthesia
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 120 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 9 May 2025to 4 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- clusion Criteria:
- Adults aged 18-65 years
- ASA physical status I-II
- Scheduled for elective upper-extremity orthopedic surgery
- Able to provide informed consent
- Able to understand and complete study questionnaires
Who cannot join
- Contraindications to regional anesthesia
- Coagulopathy or bleeding disorders
- Local infection at the block site
- Patient refusal of regional anesthesia
- Known allergy to local anesthetic agents
- Chronic opioid use (daily use for >3 months)
Show all 12Show fewer
- Psychiatric disorders preventing cooperation or consent
- Pregnancy or breastfeeding
- Severe respiratory disease (for general anesthesia group)
- Pre-existing neurological deficit in the operative extremity
- Emergency surgery
- ASA physical status III or higher
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Adana City Training and Research Hospital
Adana, Adana, 01150
About this study
Official title: Comparison of Brachial Plexus Block Versus General Anesthesia for Upper Extremity Surgery: A Randomized Controlled Trial
This study compares two different anesthesia methods for upper arm and hand surgery: regional anesthesia (brachial plexus block) versus general anesthesia.
Regional anesthesia numbs only the arm being operated on by injecting local anesthetic near the nerves, while the patient remains awake or lightly sedated. General anesthesia puts the patient completely asleep using medications given through a breathing tube.
Read more
The main goals of this study are to compare:
- How much pain patients experience after surgery
- Patient satisfaction with their anesthesia
- Side effects such as nausea, vomiting, or breathing problems
- Time until patients are ready to go home
- Overall safety of each method
Participants in this study will be randomly assigned to receive either brachial plexus block or general anesthesia for their scheduled upper extremity surgery. The research team will monitor participants during surgery and follow their recovery for 24 hours after the operation.
This research will help doctors and patients make better-informed decisions about which type of anesthesia may be best for upper extremity procedures.
- Being tested
- Brachial Plexus Block, General Anesthesia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Brachial Plexus BlockProcedure or surgery
Ultrasound-guided infraclavicular brachial plexus block using local anesthetic (e.g., ropivacaine or bupivacaine). Block performed before surgery to provide regional anesthesia for upper extremity surgery.
General AnesthesiaProcedure or surgery
Standard general anesthesia with intravenous induction and maintenance with volatile anesthetics or total intravenous anesthesia (TIVA). Endotracheal intubation or laryngeal mask airway used as appropriate.
| Study group | Role | What they receive |
|---|---|---|
| Brachial Plexus Block Group | Active comparator | Patients receiving ultrasound-guided brachial plexus block for upper extremity surgery Receives: Procedure: Brachial Plexus Block |
| General Anesthesia Group | Active comparator | Patients receiving general anesthesia for upper extremity surgery Receives: Procedure: General Anesthesia |
What is being measured
The primary outcome is the main question the study is designed to answer.
Preoperative Anxiety Score
Preoperative anxiety measured immediately prior to operating room entry using the State-Trait Anxiety Inventory-State (STAI-S) scale. STAI-S is a validated 20-item questionnaire assessing current state anxiety. Scores range from 20 to 80, with higher scores indicating greater anxiety levels.
Measured: Immediately before operating room entry (preoperatively)
Secondary outcomes (6)
Postoperative Pain Score
Pain intensity measured using Visual Analog Scale (VAS) at multiple time points after surgery. VAS scores range from 0 to 10, where 0 indicates no pain and 10 indicates worst pain imaginable. Lower scores indicate better outcome.
Measured: From end of surgery to 24 hours postoperatively
Opioid Consumption
Total opioid consumption measured as morphine equivalent dose (mg) during the postoperative period. All opioid medications administered were converted to morphine equivalents using standard conversion factors. Lower consumption indicates better outcome.
Measured: From end of surgery to 24 hours postoperatively
Number of Participants with Postoperative Nausea and Vomiting (PONV)
Number of participants experiencing postoperative nausea and/or vomiting requiring antiemetic treatment during the postoperative period. PONV was defined as any episode of nausea or vomiting reported by the patient or requiring rescue antiemetic medication.
Measured: First 24 hours postoperatively
PACU Length of Stay
Duration of stay in the Post-Anesthesia Care Unit (PACU) measured in minutes, from admission to discharge readiness based on standardized discharge criteria (Aldrete score ≥9). Shorter stay indicates better recovery.
Measured: From PACU admission until discharge readiness (typically 0-4 hours postoperatively
Quality of Recovery (QoR-15) Score
Patient-reported quality of recovery assessed using the validated Quality of Recovery-15 (QoR-15) questionnaire. QoR-15 is a 15-item instrument measuring five dimensions of recovery: physical comfort, emotional state, psychological support, physical independence, and pain. Each item is scored 0-10, with total scores ranging from 0 to 150. Higher scores indicate better quality of recovery.
Measured: 24 hours postoperatively
Patient Satisfaction Score
Overall patient satisfaction with anesthesia care measured using a numerical rating scale from 0 to 5, where 0 indicates completely dissatisfied and 5 indicates completely satisfied. Patients were asked to rate their overall satisfaction with the anesthesia experience.
Measured: 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start9 May 2025
- Primary completion3 Nov 2025
- Study completion4 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Upper Extremity SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 120 participants (actual)
Sponsor and investigators
- Lead sponsor
- Adana City Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dilek Uçak, Adana City Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07352839
- Sponsor's protocol ID
- 536
- Status last verified
- Jan 2026
- First submitted
- 30 Dec 2025
- Last updated
- 20 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Brachial Plexus Block Versus General Anesthesia for Upper Extremity Surgery: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07352839
- Acronym / sponsor ID
- 536
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 120 participants (actual)
- Lead sponsor
- Adana City Training and Research HospitalUniversity, hospital or other
- Study start
- 9 May 2025 (actual)
- Primary completion
- 3 Nov 2025 (actual)
- Study completion
- 4 Nov 2025 (actual)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compares two different anesthesia methods for upper arm and hand surgery: regional anesthesia (brachial plexus block) versus general anesthesia.
Regional anesthesia numbs only the arm being operated on by injecting local anesthetic near the nerves, while the patient remains awake or lightly sedated. General anesthesia puts the patient completely asleep using medications given through a breathing tube.
The main goals of this study are to compare:
- How much pain patients experience after surgery
- Patient satisfaction with their anesthesia
- Side effects such as nausea, vomiting, or breathing problems
- Time until patients are ready to go home
- Overall safety of each method
Participants in this study will be randomly assigned to receive either brachial plexus block or general anesthesia for their scheduled upper extremity surgery. The research team will monitor participants during surgery and follow their recovery for 24 hours after the operation.
This research will help doctors and patients make better-informed decisions about which type of anesthesia may be best for upper extremity procedures.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Brachial Plexus Block Group | Active comparator | Procedure: Brachial Plexus BlockPatients receiving ultrasound-guided brachial plexus block for upper extremity surgery |
| General Anesthesia Group | Active comparator | Procedure: General AnesthesiaPatients receiving general anesthesia for upper extremity surgery |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- clusion Criteria:
- Adults aged 18-65 years
- ASA physical status I-II
- Scheduled for elective upper-extremity orthopedic surgery
- Able to provide informed consent
Key exclusion criteria (12 listed)
- Contraindications to regional anesthesia
- Coagulopathy or bleeding disorders
- Local infection at the block site
- Patient refusal of regional anesthesia
- Known allergy to local anesthetic agents
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Brachial Plexus BlockUltrasound-guided infraclavicular brachial plexus block using local anesthetic (e.g., ropivacaine or bupivacaine). Block performed before surgery to provide regional anesthesia for upper extremity surgery. | Procedure or surgery | Brachial Plexus Block Group |
| General AnesthesiaStandard general anesthesia with intravenous induction and maintenance with volatile anesthetics or total intravenous anesthesia (TIVA). Endotracheal intubation or laryngeal mask airway used as appropriate. | Procedure or surgery | General Anesthesia Group |
Primary outcome
Preoperative Anxiety Score
Time frame: Immediately before operating room entry (preoperatively)
Preoperative anxiety measured immediately prior to operating room entry using the State-Trait Anxiety Inventory-State (STAI-S) scale. STAI-S is a validated 20-item questionnaire assessing current state anxiety. Scores range from 20 to 80, with higher scores indicating greater anxiety levels.
6 secondary outcomes
Postoperative Pain Score
Time frame: From end of surgery to 24 hours postoperatively
Opioid Consumption
Time frame: From end of surgery to 24 hours postoperatively
Number of Participants with Postoperative Nausea and Vomiting (PONV)
Time frame: First 24 hours postoperatively
PACU Length of Stay
Time frame: From PACU admission until discharge readiness (typically 0-4 hours postoperatively
Quality of Recovery (QoR-15) Score
Time frame: 24 hours postoperatively
Patient Satisfaction Score
Time frame: 24 hours postoperatively
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Jan 2026.
- Individual participant dataSharing planned: No
Related trials for Upper Extremity Surgery
Recruiting
Hemocoll, Avitene, or Bone Wax for Cancellous Bone Bleeding After Single-Ray Amputation
Hemostasis, Surgical Blood Loss
Recruiting
Evaluation of the Aulea Veloxion™ Disposable Resectoscope System for Operational Efficiency in Surgical Management of Benign Prostatic Hyperplasia (BPH)
BPH (Benign Prostatic Hyperplasia)
Recruiting
Digital Eye®-Assisted Bone Density Classification and Primary Dental Implant Stability.
Bone Mineral Density, Primary Implant Stability
Active, not recruiting
Feasibility Study of Middle Segmental Gastrectomy (MSG) for Gastric Cancer.
Gastric Cancer, Gastric Adenocarcinoma
Active, not recruitingPhase 1/2
A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer
Bladder Cancer, Metastatic Bladder Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Brachial Plexus Block and General Anesthesia in people with Upper Extremity Surgery and Regional Anesthesia, run by Adana City Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Preoperative Anxiety Score (time frame: Immediately before operating room entry (preoperatively)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Jan 2026.