AsthmaButeyko BreathNCT07353242
The Effect of Buteyko Breathing Technique on Asthma Patients
A study testing Buteyko Breathing Technique in people with Asthma, run by University of Gaziantep at 1 site in Turkey (Türkiye).
Trial summary
This study was designed as a pre-test-post-test randomized controlled experimental trial to determine the effects of buteyko breathing technique application on fatigue, exercise capacity, and asthma control in asthma patients.The study, planned as a randomized controlled experimental study, included a total of 90… Read more about this study
- Who is it for?
- Ages 18 to 59 years
- Conditions the study is for
- Asthma
- What is being tested?
- Buteyko Breathing Technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Oct 2024to 25 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 59 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Having been diagnosed with asthma within the last 6 months
- Absence of heart failure
- Absence of communication and perception problems
- Absence of walking impairment Being between 18-59 years of age-
Who cannot join
- -Child patients
- Those diagnosed with heart failure
- Conditions that impede walking
- Those with communication and perception problems
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Gaziantep University
Gaziantep, Şehitkamil, 27000
About this study
Official title: "THE EFFECT OF BUTEIKO RESPIRATORY TECHNIQUE APPLIED TO ASTHMA PATIENTS ON FATIGUE, EXERCISE CAPACITY, AND ASTHMA CONTROL"
This study was designed as a pre-test-post-test randomized controlled experimental trial to determine the effects of buteyko breathing technique application on fatigue, exercise capacity, and asthma control in asthma patients.The study, planned as a randomized controlled experimental study, included a total of 90 participants.
The sample consisted of asthma patients who applied to the Chest Diseases outpatient clinic of Gaziantep University Application and Research Hospital, had been diagnosed with asthma within the last 6 months, did not have heart failure, did not have communication or perception problems, did not have walking disabilities, and were between 18-59 years old.Following random assignment, participants were divided into two groups of 45 participants each. The groups were: 1) Buteyko 2) Control
Read the detailed description
Asthma is a chronic inflammatory airway disease that affects individuals of all ages and represents a major public health problem due to its high prevalence and substantial clinical, social, and economic burden. In addition to respiratory symptoms, fatigue and functional limitations are common yet often overlooked in individuals with asthma, significantly impairing daily life. Alongside pharmacological treatments, low-cost, safe, and easily applicable non-pharmacological approaches are gaining increasing importance in asthma management. One such approach is the Buteyko breathing technique, a non-pharmacological breathing retraining method aimed at reducing hyperventilation, improving breathing patterns, and alleviating asthma symptoms. However, evidence regarding the effects of the Buteyko breathing technique on fatigue, functional exercise capacity, and asthma control remains limited. Therefore, this study aims to evaluate the effects of the Buteyko breathing technique on fatigue levels, functional exercise capacity, and asthma control in patients with asthma.
- Conditions
- Asthma
- Being tested
- Buteyko Breathing Technique
- Keywords
- Asthma,, Buteyko, Fatigue, Breathing Exercises, Exercise Capacity, Asthma Control
- Medical subject headings
- Asthma, Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Buteyko Breathing TechniqueOther
This intervention is distinguished by its standardized delivery by an internationally certified Buteyko practitioner and its integration of key Buteyko components, including reduced breathing, controlled breath-holding, nasal breathing with mouth taping, and relaxation. It incorporates both seated and walking-based exercises, uses objective measures such as Control Pause and step counting, and includes a structured home-based practice with weekly follow-up over six weeks.
| Study group | Role | What they receive |
|---|---|---|
| Buteyko group | Experimental | In the Buteyko group, in addition to standard treatment, participants received training and practice in the Buteyko Breathing Technique aimed at reducing hyperventilation. The intervention was delivered as face-to-face group training by an internationally certified instructor and included a 30-minute theoretical session followed by practical exercises. These consisted of controlled breath-holding with reduced breathing performed while seated and walking, as well as a relaxation phase focusing on nasal breathing accompanied by calming music. Mouth taping was used throughout the exercises to promote nasal breathing. Participants were instructed to perform the exercises at home three times daily, with weekly outpatient follow-up visits, and were monitored for a total of six weeks. Receives: Other: Buteyko Breathing Technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
The Asthma Control Test (ACT)
The Asthma Control Test (ACT) is a practical, patient-completed scale consisting of five questions, scored between 5 and 25 points, that assesses the level of asthma control; higher scores indicate better control.
Measured: 6 weeks
Secondary outcomes (1)
The Chronic Obstructive Pulmonary Disease and Asthma Fatigue Scale (COPD)
The Chronic Obstructive Pulmonary Disease and Asthma Fatigue Scale (COPD) is a 12-item, five-point Likert-type scale that assesses fatigue in individuals with asthma and COPD; higher scores indicate higher fatigue levels.
Measured: 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Jan 2026
- Study start15 Oct 2024
- Primary completion25 Jun 2025
- Study completion25 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for AsthmaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Gaziantep
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Adile Nese, University of Gaziantep
- Investigators
- Adile Neşe, Study director, University of Gaziantep
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07353242
- Sponsor's protocol ID
- Buteyko Breathing Technique
- Acronym
- Buteyko Breath
- Status last verified
- Jan 2026
- First submitted
- 13 Jan 2026
- Last updated
- 20 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Aluwı, M. F., Azmı, N. A., Zanudın, A., & Ramlı, A. (2025). Effect of Buteyko Breathing Technique and Inspiratory Muscle Training on Acute Exacerbation of Bronchial Asthma in a 55-Year-Old Patient: A Case Report. Buletin SK, 9(1), 55-60
AbdElmawla Elsaid, R. A., Zahran, W. E. K., & Elsaid Hafez, D. M. (2023). Comparison of the Effects of Buteyko and Diaphragmatic Breathing Technique on Improving Pulmonary Functions and Asthma Control among Patients with Bronchial Asthma. Egyptian Journal of Nursing and Health Sciences, 4(3), 58-76.
Abd Allah Abd El Hafeez, N., Khalil Hafez, M., Mohamed Ahmed, Z., Metwally El-Sayed, M., Abdelwahab Khedr, M., & Fathy Ahmed Dawood, R. (2025). Evaluating the Effect of Buteyko Breathing Technique in Enhancing Asthma Control and Life Quality Among Asthma Patients: A Nursing-Led Quasi-Experimental Study. Egyptian Journal of Health Care, 16(1), 831-852.
Study at a glance
From the registry record, last updated by the sponsor on 20 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- "THE EFFECT OF BUTEIKO RESPIRATORY TECHNIQUE APPLIED TO ASTHMA PATIENTS ON FATIGUE, EXERCISE CAPACITY, AND ASTHMA CONTROL"
- ClinicalTrials.gov ID
- NCT07353242
- Acronym / sponsor ID
- Buteyko Breath / Buteyko Breathing Technique
- Conditions
- Asthma
- Keywords
- Asthma,, Buteyko, Fatigue, Breathing Exercises, Exercise Capacity, Asthma Control
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- University of GaziantepUniversity, hospital or other
- Study start
- 15 Oct 2024 (actual)
- Primary completion
- 25 Jun 2025 (actual)
- Study completion
- 25 Jul 2025 (actual)
- First posted
- 20 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was designed as a pre-test-post-test randomized controlled experimental trial to determine the effects of buteyko breathing technique application on fatigue, exercise capacity, and asthma control in asthma patients.The study, planned as a randomized controlled experimental study, included a total of 90 participants.
The sample consisted of asthma patients who applied to the Chest Diseases outpatient clinic of Gaziantep University Application and Research Hospital, had been diagnosed with asthma within the last 6 months, did not have heart failure, did not have communication or perception problems, did not have walking disabilities, and were between 18-59 years old.Following random assignment, participants were divided into two groups of 45 participants each. The groups were: 1) Buteyko 2) Control
Detailed description
Asthma is a chronic inflammatory airway disease that affects individuals of all ages and represents a major public health problem due to its high prevalence and substantial clinical, social, and economic burden. In addition to respiratory symptoms, fatigue and functional limitations are common yet often overlooked in individuals with asthma, significantly impairing daily life. Alongside pharmacological treatments, low-cost, safe, and easily applicable non-pharmacological approaches are gaining increasing importance in asthma management. One such approach is the Buteyko breathing technique, a non-pharmacological breathing retraining method aimed at reducing hyperventilation, improving breathing patterns, and alleviating asthma symptoms. However, evidence regarding the effects of the Buteyko breathing technique on fatigue, functional exercise capacity, and asthma control remains limited. Therefore, this study aims to evaluate the effects of the Buteyko breathing technique on fatigue levels, functional exercise capacity, and asthma control in patients with asthma.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Buteyko group | Experimental | Other: Buteyko Breathing TechniqueIn the Buteyko group, in addition to standard treatment, participants received training and practice in the Buteyko Breathing Technique aimed at reducing hyperventilation. The intervention was delivered as face-to-face group training by an internationally certified instructor and included a 30-minute theoretical session followed by practical exercises. These consisted of controlled breath-holding with reduced breathing performed while seated and walking, as well as a relaxation phase focusing on nasal breathing accompanied by calming music. Mouth taping was used throughout the exercises to promote nasal breathing. Participants were instructed to perform the exercises at home three times daily, with weekly outpatient follow-up visits, and were monitored for a total of six weeks. |
Who may qualify
- Ages
- 18 to 59 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Having been diagnosed with asthma within the last 6 months
- Absence of heart failure
- Absence of communication and perception problems
- Absence of walking impairment Being between 18-59 years of age-
Key exclusion criteria (4 listed)
- -Child patients
- Those diagnosed with heart failure
- Conditions that impede walking
- Those with communication and perception problems
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Buteyko Breathing TechniqueThis intervention is distinguished by its standardized delivery by an internationally certified Buteyko practitioner and its integration of key Buteyko components, including reduced breathing, controlled breath-holding, nasal breathing with mouth taping, and relaxation. It incorporates both seated and walking-based exercises, uses objective measures such as Control Pause and step counting, and includes a structured home-based practice with weekly follow-up over six weeks. | Other | Buteyko group |
Primary outcome
The Asthma Control Test (ACT)
Time frame: 6 weeks
The Asthma Control Test (ACT) is a practical, patient-completed scale consisting of five questions, scored between 5 and 25 points, that assesses the level of asthma control; higher scores indicate better control.
1 secondary outcome
The Chronic Obstructive Pulmonary Disease and Asthma Fatigue Scale (COPD)
Time frame: 6 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Jan 2026.
- Results publicationAluwı, M. F., Azmı, N. A., Zanudın, A., & Ramlı, A. (2025). Effect of Buteyko Breathing Technique and Inspiratory Muscle Training on Acute Exacerbation of Bronchial Asthma in a 55-Year-Old Patient: A Case Report. Buletin SK, 9(1), 55-60
- Results publicationAbdElmawla Elsaid, R. A., Zahran, W. E. K., & Elsaid Hafez, D. M. (2023). Comparison of the Effects of Buteyko and Diaphragmatic Breathing Technique on Improving Pulmonary Functions and Asthma Control among Patients with Bronchial Asthma. Egyptian Journal of Nursing and Health Sciences, 4(3), 58-76.
- Results publicationAbd Allah Abd El Hafeez, N., Khalil Hafez, M., Mohamed Ahmed, Z., Metwally El-Sayed, M., Abdelwahab Khedr, M., & Fathy Ahmed Dawood, R. (2025). Evaluating the Effect of Buteyko Breathing Technique in Enhancing Asthma Control and Life Quality Among Asthma Patients: A Nursing-Led Quasi-Experimental Study. Egyptian Journal of Health Care, 16(1), 831-852.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Adile Neşe study director
University of Gaziantep
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Buteyko Breathing Technique in people with Asthma, run by University of Gaziantep at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The Asthma Control Test (ACT) (time frame: 6 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07353242, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Jan 2026.