VolunteerVASC-STIMNCT07354607
Effect of Transcutaneous Electrical Stimulation on Peripheral Blood Flow
A study testing transcutaneous electrical nerve stimulation in people with Volunteer and Adult, run by Centre Hospitalier Metropole Savoie at 1 site in France.
Trial summary
The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation can affect blood flow in healthy volunteers. The main question it aims to answer is: Determine the stimulation parameters (frequency in the range 5- 100Hz and proximal or distal placement) inducing the most significant… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- What is being tested?
- transcutaneous electrical nerve stimulation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteFrance
- Study dates
- 4 Feb 2026to 1 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Subject aged 18 years or older
- Having freely given written consent, after being informed of the purpose of the study, its conduct and its risks.
- Affiliated with a social security scheme
Who cannot join
- Persons with pacemakers or any other implantable electrical devices,
- Pregnant women
- Suffering from dermatological conditions or muscle/skin lesions on the arms and forearms.
- Participant unable to give free and informed consent.
- Participant unable to comply with the specific procedures of the study.
- Participant deprived of liberty or benefiting from legal protection measures.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Centre Hospitalier Métropole Savoie
Chambéry, 73000
leo blervaque, +33479965910, leo.blervaque@ch-metropole-savoie.fr
florence jego, ARC, +33479965910, florence.jego@ch-metropole-savoie.fr
About this study
Official title: Effect of Transcutaneous Electrical Stimulation on Peripheral Blood Flow - a Pilot Study
The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation can affect blood flow in healthy volunteers. The main question it aims to answer is:
Determine the stimulation parameters (frequency in the range 5- 100Hz and proximal or distal placement) inducing the most significant hyperaemic response in volunteers.
Participants will attend to one visit ( 1h30) , 6 protocol of stimulation will be tested on his arm . If his agree, an optionnal measure will be made during another visit. During this optionnal visit, two modalities of intensity adjustment will be tested in regard of the result of the first part of the study.
- Being tested
- transcutaneous electrical nerve stimulation
- Keywords
- transcutaneous electrical nerve stimulation, blood flow
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
transcutaneous electrical nerve stimulationOther
transcutaneous electrical nerve stimulation on arm. 6 different protocol will be apply testing different modality of frequency and positionnement of electrodes
| Study group | Role | What they receive |
|---|---|---|
| experimental group | Experimental | transcutaneous electrical nerve stimulation Receives: Other: transcutaneous electrical nerve stimulation |
What is being measured
The primary outcome is the main question the study is designed to answer.
stimulation parameters that induce the most significant hyperaemic response
Determine the stimulation parameters (frequency in the range 5- 100Hz and proximal or distal placement) that induce the most significant hyperaemic response in volunteers.
Measured: from enrollment to the end of the procedure (1h30)
Secondary outcomes (3)
Assess the score on a scale of disconfort level during stimulation for each condition
The outcome will be assess using a visual analogic disconfort scale ranging from 0 (no disconfort) to 10 (the highest disconfort imaginable).
Measured: during testing procedure
Compare stimulation intensities between each condition
Measured: during testing procedure
Compare muscle metabolic demand between each condition
Measured: during testing procedure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Jan 2026
- Study start4 Feb 2026
- Primary completion1 Aug 2026 (estimated)
- Study completion1 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for VolunteerStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 36 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Metropole Savoie
- Sponsor type
- University, hospital or other
- Collaborators
- Laboratoire Interuniversitaire de Biologie de la Motricité, Université Savoie Mont Blanc
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07354607
- Sponsor's protocol ID
- CHMS25010
- Other IDs
- 2025-A02335-44
- Acronym
- VASC-STIM
- Status last verified
- Mar 2026
- First submitted
- 30 Dec 2025
- Last updated
- 10 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: exploratory research at this time
Study at a glance
From the registry record, last updated by the sponsor on 10 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Transcutaneous Electrical Stimulation on Peripheral Blood Flow - a Pilot Study
- ClinicalTrials.gov ID
- NCT07354607
- Acronym / sponsor ID
- VASC-STIM / CHMS25010
- Keywords
- transcutaneous electrical nerve stimulation, blood flow
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 36 participants (estimated)
- Lead sponsor
- Centre Hospitalier Metropole SavoieUniversity, hospital or other
- Collaborators
- Laboratoire Interuniversitaire de Biologie de la Motricité, Université Savoie Mont Blanc
- Study start
- 4 Feb 2026 (actual)
- Primary completion
- 1 Aug 2026 (estimated)
- Study completion
- 1 Aug 2026 (estimated)
- First posted
- 21 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn if transcutaneous electrical nerve stimulation can affect blood flow in healthy volunteers. The main question it aims to answer is:
Determine the stimulation parameters (frequency in the range 5- 100Hz and proximal or distal placement) inducing the most significant hyperaemic response in volunteers.
Participants will attend to one visit ( 1h30) , 6 protocol of stimulation will be tested on his arm . If his agree, an optionnal measure will be made during another visit. During this optionnal visit, two modalities of intensity adjustment will be tested in regard of the result of the first part of the study.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| experimental group | Experimental | Other: transcutaneous electrical nerve stimulationtranscutaneous electrical nerve stimulation |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Subject aged 18 years or older
- Having freely given written consent, after being informed of the purpose of the study, its conduct and its risks.
- Affiliated with a social security scheme
Key exclusion criteria (6 listed)
- Persons with pacemakers or any other implantable electrical devices,
- Pregnant women
- Suffering from dermatological conditions or muscle/skin lesions on the arms and forearms.
- Participant unable to give free and informed consent.
- Participant unable to comply with the specific procedures of the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| transcutaneous electrical nerve stimulationtranscutaneous electrical nerve stimulation on arm. 6 different protocol will be apply testing different modality of frequency and positionnement of electrodes | Other | experimental group |
Primary outcome
stimulation parameters that induce the most significant hyperaemic response
Time frame: from enrollment to the end of the procedure (1h30)
Determine the stimulation parameters (frequency in the range 5- 100Hz and proximal or distal placement) that induce the most significant hyperaemic response in volunteers.
3 secondary outcomes
Assess the score on a scale of disconfort level during stimulation for each condition
Time frame: during testing procedure
Compare stimulation intensities between each condition
Time frame: during testing procedure
Compare muscle metabolic demand between each condition
Time frame: during testing procedure
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Mar 2026.
- Individual participant dataSharing planned: Undecided. exploratory research at this time
Related trials for Volunteer
Not yet recruiting
Neuroergonomic Analysis of a Brain-Computer Interface Device (BCI)
Healthy Volunteers - Male and Female
RecruitingPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Healthy Volunteer, Atopic Dermatitis
Not yet recruitingObservational study
Establishment of Biobank of Nasal Epithelium Samples From Healthy Volunteers
Healthy
RecruitingObservational study
Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives
Graft-Versus-Host Disease, Graft-versus-leukemia
Not yet recruitingObservational study
Screening Protocol
Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing transcutaneous electrical nerve stimulation in people with Volunteer and Adult, run by Centre Hospitalier Metropole Savoie at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 10 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact leo blervaque (+33 4 79 96 59 10, leo.blervaque@ch-metropole-savoie.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
stimulation parameters that induce the most significant hyperaemic response (time frame: from enrollment to the end of the procedure (1h30)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Mar 2026.