Idiopathic ScoliosisEYAISNCT07356999
Characterization of Visual Perception Impairments in Patients With Idiopathic Scoliosis
A study testing Motion Analysis in people with Idiopathic Scoliosis, run by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française at 1 site in France.
Trial summary
Scoliosis is more than just a curve in the spine; it is a complex, 3D twisting of the backbone. While it can be caused by birth defects or tumors, the most common type-idiopathic scoliosis-appears in healthy teenagers for no clearly known reason. Read more about this study
- Who is it for?
- Ages 11 to 18 yearsHealthy volunteers can take part
- Conditions the study is for
- Idiopathic Scoliosis
- What is being tested?
- Motion Analysis
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteFrance
- Study dates
- 21 Apr 2026to 1 Sep 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 11 to 18 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Group Scoliosis:
- Girls or boys aged 11 to 18 inclusive.
- Patients with progressive idiopathic scoliosis
- Candidates for either orthopedic (brace) or surgical (arthrodesis correction) treatment for which a pre-therapeutic multimodal assessment is planned.
- Control group:
- Girls or boys aged 11 to 18 inclusive.
Who cannot join
- The following individuals will not be included:
- Individuals with another musculoskeletal disorder.
- Individuals with a neurosensory disorder that may affect the balance of the trunk or lower limbs.
- Individuals with uncorrected visual perception disorders (visual check within 12 months prior to the examination).
- Lack of consent from the subject.
- Lack of consent from legal representatives.
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- Failure to understand the instructions for performing the tests.
- In addition, for the control group:
- Suffering from scoliosis
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Centre Médico chirurgical de Réadaptation des Massues
Lyon, 69005
Julie Rozaire, PhD, +33 4 72 38 11 43, lab.massues@croix-rouge.fr
About this study
Official title: Characterization of Visual Perception Alterations in Patients With Idiopathic Scoliosis: Towards a Theory of Perceptual Imbalance
Scoliosis is more than just a curve in the spine; it is a complex, 3D twisting of the backbone. While it can be caused by birth defects or tumors, the most common type-idiopathic scoliosis-appears in healthy teenagers for no clearly known reason.
The Theory of Balance Researchers believe that scoliosis might actually be caused by a "glitch" in how the body stays upright. Instead of the spine curving on its own, the curve might be the body's way of compensating for a poor sense of balance.
Read more
To stay balanced, the human brain relies on three main "inputs":
- The Vestibular System: Located in the inner ear (detects movement).
- Proprioception: The body's "inner map" (sensing where your limbs are).
- Vision: Seeing the world around you to stay oriented.
The Goal of the Study Even though humans rely heavily on their eyes to stay balanced, the role of vision in scoliosis has not been studied very much.
This experiment aims to test the hypothesis that teenagers with scoliosis have trouble processing visual information to maintain their posture. By using advanced motion analysis, researchers want to see if a "misunderstanding" of visual cues is contributing to the spinal deformity.
- Conditions
- Idiopathic Scoliosis
- Being tested
- Motion Analysis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Motion AnalysisOther
Researchers use motion capture to track exactly how a patient's body moves and shifts in response to different environments.
| Study group | Role | What they receive |
|---|---|---|
| Vertical Perception Assessment | Experimental | Not described Receives: Other: Motion Analysis |
What is being measured
The primary outcome is the main question the study is designed to answer.
Margin of Dynamic Stability
This measures how close a person is to losing their balance while moving. It calculates the distance between where the body's weight is moving and the edge of the person's "footprint" (base of support).
Measured: At enrollment
Center of Pressure
The point on the ground where the most weight is being concentrated. Tracking how much this point "wobbles" or shifts shows how hard the body is working to stay upright.
Measured: At enrollment
Extrapolated Center of Mass
A calculation that looks at both the position of the body and its velocity. It helps researchers predict if the person's momentum is about to carry them off-balance.
Measured: At enrollment
Secondary outcomes (3)
Base of Support
The total area on the ground occupied by the feet. A wider BoS often suggests the subject is trying to create a "wider stance" to feel more stable.
Measured: At enrollment
Visual Field Perception
The "Distance Error." Using a joystick, the patient tries to place a 3D avatar exactly halfway between two other figures. The difference between the true middle and where the patient thinks the middle is reveals if their depth perception is distorted.
Measured: At enrollment
Subjective Visual Vertical
Angular Error. A glowing line is tilted on a screen, and the patient must tell the operator how to rotate it until it is perfectly vertical.
Measured: At enrollment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Jan 2026
- Study start21 Apr 2026
- Primary completion1 Sep 2027 (estimated)
- Study completion1 Sep 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Idiopathic ScoliosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 70 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07356999
- Sponsor's protocol ID
- 2025_10_EYAIS_RIPH2
- Other IDs
- 2025-A01301-48
- Acronym
- EYAIS
- Status last verified
- May 2026
- First submitted
- 13 Jan 2026
- Last updated
- 26 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Characterization of Visual Perception Alterations in Patients With Idiopathic Scoliosis: Towards a Theory of Perceptual Imbalance
- ClinicalTrials.gov ID
- NCT07356999
- Acronym / sponsor ID
- EYAIS / 2025_10_EYAIS_RIPH2
- Conditions
- Idiopathic Scoliosis
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 70 participants (estimated)
- Lead sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge FrançaiseUniversity, hospital or other
- Study start
- 21 Apr 2026 (actual)
- Primary completion
- 1 Sep 2027 (estimated)
- Study completion
- 1 Sep 2027 (estimated)
- First posted
- 21 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Scoliosis is more than just a curve in the spine; it is a complex, 3D twisting of the backbone. While it can be caused by birth defects or tumors, the most common type-idiopathic scoliosis-appears in healthy teenagers for no clearly known reason.
The Theory of Balance Researchers believe that scoliosis might actually be caused by a "glitch" in how the body stays upright. Instead of the spine curving on its own, the curve might be the body's way of compensating for a poor sense of balance.
To stay balanced, the human brain relies on three main "inputs":
- The Vestibular System: Located in the inner ear (detects movement).
- Proprioception: The body's "inner map" (sensing where your limbs are).
- Vision: Seeing the world around you to stay oriented.
The Goal of the Study Even though humans rely heavily on their eyes to stay balanced, the role of vision in scoliosis has not been studied very much.
This experiment aims to test the hypothesis that teenagers with scoliosis have trouble processing visual information to maintain their posture. By using advanced motion analysis, researchers want to see if a "misunderstanding" of visual cues is contributing to the spinal deformity.
Study design
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Vertical Perception Assessment | Experimental | Other: Motion Analysis |
Who may qualify
- Ages
- 11 to 18 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (6 listed)
- Girls or boys aged 11 to 18 inclusive.
- Patients with progressive idiopathic scoliosis
- Candidates for either orthopedic (brace) or surgical (arthrodesis correction) treatment for which a pre-therapeutic multimodal assessment is planned.
- Girls or boys aged 11 to 18 inclusive.
Key exclusion criteria (9 listed)
- Individuals with another musculoskeletal disorder.
- Individuals with a neurosensory disorder that may affect the balance of the trunk or lower limbs.
- Individuals with uncorrected visual perception disorders (visual check within 12 months prior to the examination).
- Lack of consent from the subject.
- Lack of consent from legal representatives.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Motion AnalysisResearchers use motion capture to track exactly how a patient's body moves and shifts in response to different environments. | Other | Vertical Perception Assessment |
Primary outcome
Margin of Dynamic Stability
Time frame: At enrollment
This measures how close a person is to losing their balance while moving. It calculates the distance between where the body's weight is moving and the edge of the person's "footprint" (base of support).
Center of Pressure
Time frame: At enrollment
The point on the ground where the most weight is being concentrated. Tracking how much this point "wobbles" or shifts shows how hard the body is working to stay upright.
Extrapolated Center of Mass
Time frame: At enrollment
A calculation that looks at both the position of the body and its velocity. It helps researchers predict if the person's momentum is about to carry them off-balance.
3 secondary outcomes
Base of Support
Time frame: At enrollment
Visual Field Perception
Time frame: At enrollment
Subjective Visual Vertical
Time frame: At enrollment
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 May 2026.
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Turkish Adaptation and Validation of the Scoliosis Misconception Scale in Adolescents With Idiopathic Scoliosis
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Centre Médico chirurgical de Réadaptation des Massues
Lyon, France
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Motion Analysis in people with Idiopathic Scoliosis, run by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Margin of Dynamic Stability (time frame: At enrollment). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 May 2026.