Rheumatoid ArthritisNCT07360496
Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis
An observational study of Rheumatoid Arthritis and Healthy Control, run by Cumhuriyet University at 1 site in Turkey (Türkiye).
Trial summary
This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Rheumatoid Arthritis, Healthy Control
- How many people
- 113 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 8 Dec 2022to 28 Aug 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Patients RA diagnosis and health Controls
- RA Group Inclusion Criteria:
- Diagnosed with RA according to ACR/EULAR criteria
- Between 18-65 years of age
- Willing to participate in the study
RA Group Exclusion Criteria:
- Having any chronic disease other than RA
- Having another musculoskeletal disease
- Having adaptation problems and psychiatric illnesses that would impair participation in the study
- Having hearing loss that would impair communication
- Having severe vision loss
- Having another rheumatic disease other than RA
- Having any uncontrolled cardiopulmonary disease
- Having a serious deformity or severe pain in the extremities or trunk that would prevent taking a crawling position (7 or higher on a 10-point numerical pain scale) (being present)
- Hand deformity or pain severe enough to prevent finger grip strength measurements
- History of any serious trauma or injury within the last 6 months
- Changes in medication used for RA within the last 3 months
- Receiving physiotherapy or other treatment other than medication
- History of musculoskeletal surgery (trunk, extremities)
- Being pregnant or breastfeeding
Health Controls Inclusion Criteria:
- Being between 18-65 years of age
- Voluntary participation in the study Health Controls Exclusion Criteria: ● Having any diagnosed illness
- Having a history of trauma
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Investigation of the Relationships Between Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis
This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis.
Read the detailed description
The aim was to evaluate the level of RA activity and disease activity and to examine the differences between healthy controls and RA patients in terms of these results.
A total of 113 people participated in the study, including 75 patients (57 women and 18 men; mean age: 48.65±12.53) diagnosed with RA (moderate and high levels of disease activity) aged 18-65 years and 38 healthy control group members (28 women and 10 men; mean age: 45.11±10.6).
In the evaluation, finger grip strength measurements (double grip, lateral grip, three-point grip) were done using a pinchmeter. In the kor endurance measurement, the patient was asked to lift their knees off the ground in a crawling position by contracting their kor muscles and keeping their waist at a certain distance, and the time they maintained the position was recorded. Hand function with SACRAH (Skor For Assessment And Quantification Of Chronic Rheumatic Affections Of The Hands), fatigue severity with FSS (Fatigue Severity Skor) and physical activity level with FIT Index (Frequency-Intensity-Time) were measured.
- Conditions
- Rheumatoid Arthritis, Healthy Control
- Keywords
- Rheumatoid Arthritis, Core Endurance, Pinchmeter, Grip Strength, Fatigue
- Medical subject headings
- Arthritis, Rheumatoid, Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Other
Only measurements were taken.
| Study group | Role | What they receive |
|---|---|---|
| RA group | Core endurance, finger grip strength, hand function, fatigue, physical activity level, and disease activity were evaluated in patients diagnosed with RA. | |
| Healthy controls | Core endurance, finger grip strength, hand function, fatigue, and physical activity level were evaluated in healthy control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Core endurance
Modified prone plank. This test began with a crawling position, and the participant was instructed to lift their knees off the ground and maintain that position.
Measured: December 2022-September 2023
Secondary outcomes (4)
Finger grip strength
Finger grip strength (double grip, lateral grip, three-point grip) was measured using a pinchmeter.
Measured: December 2022-September 2023
Hand function
Hand function was measured with SACRAH (Score For Assessment And Quantification Of Chronic Rheumatic Affections Of The Hands). SACRAH is a scale consisting of 23 questions. Questions 1-17 assess hand function, questions 18-19 assess stiffness, and questions 20-23 assess pain. Scoring is done on a scale of 0-100, and the higher the score, the worse the outcome.
Measured: December 2022-September 2023
Fatigue severity
Fatigue severity was determined using FSS (Fatigue Severity Score).It contains 9 questions, each scored between 0-7. A total FSS score of 6.1 or higher indicates chronic fatigue.
Measured: December 2022-September 2023
Physical activity level
Determined with FIT Index (Frequency-Intensity-Time).The maximum FIT index score is 100. Higher FIT scores indicate high levels of physical activity.
Measured: December 2022-September 2023
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Jan 2026
- Study start8 Dec 2022
- Primary completion9 Sep 2023
- Study completion28 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Rheumatoid ArthritisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Other
- Enrolment
- 113 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cumhuriyet University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Selvin BALKİ, Cumhuriyet University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07360496
- Sponsor's protocol ID
- SCU-FTR-SB-05
- Status last verified
- Jan 2026
- First submitted
- 9 Jan 2026
- Last updated
- 22 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationships Between Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis
- ClinicalTrials.gov ID
- NCT07360496
- Acronym / sponsor ID
- SCU-FTR-SB-05
- Conditions
- Rheumatoid Arthritis, Healthy Control
- Keywords
- Rheumatoid Arthritis, Core Endurance, Pinchmeter, Grip Strength, Fatigue
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 113 participants (actual)
- Lead sponsor
- Cumhuriyet UniversityUniversity, hospital or other
- Study start
- 8 Dec 2022 (actual)
- Primary completion
- 9 Sep 2023 (actual)
- Study completion
- 28 Aug 2024 (actual)
- First posted
- 22 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis.
Detailed description
The aim was to evaluate the level of RA activity and disease activity and to examine the differences between healthy controls and RA patients in terms of these results.
A total of 113 people participated in the study, including 75 patients (57 women and 18 men; mean age: 48.65±12.53) diagnosed with RA (moderate and high levels of disease activity) aged 18-65 years and 38 healthy control group members (28 women and 10 men; mean age: 45.11±10.6).
In the evaluation, finger grip strength measurements (double grip, lateral grip, three-point grip) were done using a pinchmeter. In the kor endurance measurement, the patient was asked to lift their knees off the ground in a crawling position by contracting their kor muscles and keeping their waist at a certain distance, and the time they maintained the position was recorded. Hand function with SACRAH (Skor For Assessment And Quantification Of Chronic Rheumatic Affections Of The Hands), fatigue severity with FSS (Fatigue Severity Skor) and physical activity level with FIT Index (Frequency-Intensity-Time) were measured.
Study design
- Observational model
- Case-control
- Time perspective
- Other
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| RA group | – | –Core endurance, finger grip strength, hand function, fatigue, physical activity level, and disease activity were evaluated in patients diagnosed with RA. |
| Healthy controls | – | –Core endurance, finger grip strength, hand function, fatigue, and physical activity level were evaluated in healthy control |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Patients RA diagnosis and health Controls
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Only measurements were taken. | Other | Healthy controls, RA group |
Primary outcome
Core endurance
Time frame: December 2022-September 2023
Modified prone plank. This test began with a crawling position, and the participant was instructed to lift their knees off the ground and maintain that position.
4 secondary outcomes
Finger grip strength
Time frame: December 2022-September 2023
Hand function
Time frame: December 2022-September 2023
Fatigue severity
Time frame: December 2022-September 2023
Physical activity level
Time frame: December 2022-September 2023
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Rheumatoid Arthritis and Healthy Control, run by Cumhuriyet University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Core endurance (time frame: December 2022-September 2023). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Jan 2026.