Obstructive Sleep ApneaGastric CancerNCT07362706
Prolonged Extubation in Gastric Cancer With OSA
An observational study of Obstructive Sleep Apnea and Gastric Cancer (GC), run by Qilu Hospital of Shandong University at 1 site in China.
Trial summary
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea. Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Obstructive Sleep Apnea, Gastric Cancer (GC)
- What is being tested?
- Prolonging the duration of postoperative endotracheal intubation before extubation.
- Type of treatment
- Surgery or procedure
- How many people
- 240 participants
- Where
- 1 siteChina
- Study dates
- 1 Jan 2023to 30 Jun 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with gastric cancer complicated with severe sleep apnea
Who may be able to join
- Patients preoperatively diagnosed with resectable gastric cancer
- Patients without distant organ metastasis
- Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) >30 events/hour and SaO₂ <80%
- Patients with cardiopulmonary function deemed suitable for surgery
- Patients aged 18-85 years
- Patients who voluntarily joined this study and provided written informed consent
Who cannot join
- Patients with a history of or concurrent other malignant tumors
- Patients who underwent palliative resection
- Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled
- Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders
- Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: An Exploratory Study on the Impact of Prolonged Postoperative Endotracheal Extubation Time on Postoperative Complications in Gastric Cancer Patients With Severe Obstructive Sleep Apnea
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Read the detailed description
This study retrospectively included patients who underwent radical gastrectomycombined with severe obstructive sleep apnea at Qilu Hospital . Accordingto the assessment of anesthesiologists, whether the anesthetic drugs of the patients were adequatelymetabolized during the operation. The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
- Conditions
- Obstructive Sleep Apnea, Gastric Cancer (GC)
- Being tested
- Prolonging the duration of postoperative endotracheal intubation before extubation.
- Keywords
- Radical gastrectomy, Severe obstructive sleep apnea
- Medical subject headings
- Sleep Apnea, Obstructive, Stomach Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Prolonging the duration of postoperative endotracheal intubation before extubation.Procedure or surgery
The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative complications
The incidence of postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Measured: 48-72 hour
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Jan 2026
- Study start1 Jan 2023
- Primary completion10 Feb 2026 (estimated)
- Study completion30 Jun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obstructive Sleep ApneaStudies of the same condition, open and under way.
- More trials run by Qilu Hospital of Shandong UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 240 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Qilu Hospital of Shandong University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07362706
- Sponsor's protocol ID
- KYLL-202110-034-2
- Acronym
- Gastric Cancer
- Status last verified
- Mar 2025
- First submitted
- 27 Aug 2025
- Last updated
- 23 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- An Exploratory Study on the Impact of Prolonged Postoperative Endotracheal Extubation Time on Postoperative Complications in Gastric Cancer Patients With Severe Obstructive Sleep Apnea
- ClinicalTrials.gov ID
- NCT07362706
- Acronym / sponsor ID
- Gastric Cancer / KYLL-202110-034-2
- Conditions
- Obstructive Sleep Apnea, Gastric Cancer (GC)
- Keywords
- Radical gastrectomy, Severe obstructive sleep apnea
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 240 participants (estimated)
- Lead sponsor
- Qilu Hospital of Shandong UniversityUniversity, hospital or other
- Study start
- 1 Jan 2023 (actual)
- Primary completion
- 10 Feb 2026 (estimated)
- Study completion
- 30 Jun 2028 (estimated)
- First posted
- 23 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Detailed description
This study retrospectively included patients who underwent radical gastrectomycombined with severe obstructive sleep apnea at Qilu Hospital . Accordingto the assessment of anesthesiologists, whether the anesthetic drugs of the patients were adequatelymetabolized during the operation. The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with gastric cancer complicated with severe sleep apnea
Key inclusion criteria (6 listed)
- Patients preoperatively diagnosed with resectable gastric cancer
- Patients without distant organ metastasis
- Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) >30 events/hour and SaO₂ <80%
- Patients with cardiopulmonary function deemed suitable for surgery
- Patients aged 18-85 years
Key exclusion criteria (5 listed)
- Patients with a history of or concurrent other malignant tumors
- Patients who underwent palliative resection
- Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled
- Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders
- Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Prolonging the duration of postoperative endotracheal intubation before extubation.The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared. | Procedure or surgery | – |
Primary outcome
Postoperative complications
Time frame: 48-72 hour
The incidence of postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Obstructive Sleep Apnea and Gastric Cancer (GC), run by Qilu Hospital of Shandong University at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 23 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative complications (time frame: 48-72 hour). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jan 2026.