Insulin Resistance-abdominal Fats -Post Menopausal WomenDry needleNCT07365878
Effect of Dry Needling on Insulin Resistance in Obese Post Menopausal Women
A study testing Dry Needle in people with Insulin Resistance-abdominal Fats -Post Menopausal Women, run by Cairo University at 1 site in Egypt.
Trial summary
The aim of the study is to determine the effect Dry Needling of on insulin resistance in obese postmenopausal women. Read more about this study
- Who is it for?
- Ages 48 to 60 years
- Conditions the study is for
- Insulin Resistance-abdominal Fats -Post Menopausal Women
- What is being tested?
- Dry Needle
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2025to 1 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 48 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- • All participants post-menopausal from at least 3 years.
- All participants' ages will be ranged from 48-60 years old.
- All participants BMI will exceed 25-30 kg/m2.
- All participants waist hip ratio will be equal or more than 0, 90.
Who cannot join
- • Surgical liposuction within the last 12 months.
- Untreated hypo- or hyperthyroidism.
- Uncontrolled liver, kidney or cardiovascular disease or diabetes.
- Implanted pacemaker or metal implant.
- History of thrombophlebitis, any hematological disease.
- No past or present neurological and musculoskeletal disorders that will have affected health condition.
- No smoking and drinking habits.
- No psychological problems.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Dry Needling on Insulin Resistance in Obese Post- Menopausal Women
The aim of the study is to determine the effect Dry Needling of on insulin resistance in obese postmenopausal women.
Read the detailed description
Insulin resistance and abdominal obesity have a negative impact on quality of life of postmenopausal women. Obesity and, more specifically, the level of intra-abdominal fat, are positively associated with cardiovascular disease and cardiovascular disease risk factors such as increased plasma lipids and lipoproteins, hyperinsulinemia, and insulin resistance. This study has shown associations among menopause, body fat, and body fat distribution, suggesting that increased abdominal fat distribution could partially mediate the increased cardiovascular disease risk of postmenopausal women .
Abdominal obesity can reflect excess of visceral fat tissue or subcutaneous or both. Visceral fat contributes to the pathogenesis of glucose intolerance and insulin resistance. Insulin resistance is an impaired condition of glucose absorption that induced by insulin .It represents a significant medical and socioeconomic issue impacting women's health and quality of life. So there is clinical experience and documentation for the effectiveness of Dry Needling in the treatment of insulin resistance in obese post-menopausal women.
- Being tested
- Dry Needle, abdominal exercises, and medical standard care for insulin resistance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dry NeedleOther
Dry Needle has been used to treat obesity. Clinical research has found that it is particularly effective for abdominal fat loss.Dry needling in the abdominal region requires an in-depth understanding of the underlying anatomy due to significant safety risks.
abdominal exercises, and medical standard care for insulin resistanceOther
To reduce belly fat, combine core-strengthening exercises like planks, bicycle crunches, and leg raises with overall fat-burning cardio (walking, running) and a healthy diet
| Study group | Role | What they receive |
|---|---|---|
| Dry Needle | Experimental | 26 patients who were treated with Dry Needling (three times /week/4 months), abdominal exercises, and medical standard care for insulin resistance. Receives: Other: Dry Needle; Other: abdominal exercises, and medical standard care for insulin resistance |
| abdominal exercises and medical standard care for insulin resistance. | Other | While Group (B), 26 patients treated with abdominal exercises and medical standard care for insulin resistance. Receives: Other: abdominal exercises, and medical standard care for insulin resistance |
What is being measured
The primary outcome is the main question the study is designed to answer.
HOMA-IR
Outcome measures, HOMA-IR (Homeostasis Model Assessment) will be used to assess insulin resistance. HOMA-IR is a model of interactions between glucose and insulin dynamics that is then used to predict fasting steady-state glucose and insulin concentrations for a wide range of possible combinations of insulin resistance and β-cell function.
Measured: 4 months
Secondary outcomes (4)
ultrasound
Abdominal fat thickness will be assessed by ultrasound (Aplio 500-model TUS-A500, fundamentals (2B77-004EN*M)
Measured: 4 months
BMI by kg/m2
weight and height will be combined to report BMI in kg/m^2
Measured: 4 months
waist circumferences by tape
Measured: 4 months
The surface under the cumulative ranking curve (SUCRA)
The surface under the cumulative ranking curve (SUCRA) was used to rank and compare the effects of different types of exercise. SUCRA values range from 0 to 100, where 100 indicates the best treatment with no uncertainty and 0 indicates the worst treatment with no uncertainty. Thus, higher SUCRA values indicated the better effects of an exercise intervention prior to and after four-month treatment duration for both groups.
Measured: 4 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jan 2026
- Study start1 Jan 2025
- Primary completion1 Apr 2025
- Study completion1 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Insulin Resistance-abdominal Fats -Post Menopausal WomenStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 52 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shymaa Mohammed Abdo Mohammed, Cairo University
- Investigators
- Shymaa Mohammed, Principal investigator, out patient clinic ,faculty of physical therapy ,Cairo university ,Cairo,Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07365878
- Sponsor's protocol ID
- P.T.REC/012/006055
- Acronym
- Dry needle
- Status last verified
- Jan 2026
- First submitted
- 14 Dec 2025
- Last updated
- 26 Jan 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Dry Needling on Insulin Resistance in Obese Post- Menopausal Women
- ClinicalTrials.gov ID
- NCT07365878
- Acronym / sponsor ID
- Dry needle / P.T.REC/012/006055
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 52 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 1 Jan 2025 (actual)
- Primary completion
- 1 Apr 2025 (actual)
- Study completion
- 1 Dec 2025 (actual)
- First posted
- 26 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study is to determine the effect Dry Needling of on insulin resistance in obese postmenopausal women.
Detailed description
Insulin resistance and abdominal obesity have a negative impact on quality of life of postmenopausal women. Obesity and, more specifically, the level of intra-abdominal fat, are positively associated with cardiovascular disease and cardiovascular disease risk factors such as increased plasma lipids and lipoproteins, hyperinsulinemia, and insulin resistance. This study has shown associations among menopause, body fat, and body fat distribution, suggesting that increased abdominal fat distribution could partially mediate the increased cardiovascular disease risk of postmenopausal women .
Abdominal obesity can reflect excess of visceral fat tissue or subcutaneous or both. Visceral fat contributes to the pathogenesis of glucose intolerance and insulin resistance. Insulin resistance is an impaired condition of glucose absorption that induced by insulin .It represents a significant medical and socioeconomic issue impacting women's health and quality of life. So there is clinical experience and documentation for the effectiveness of Dry Needling in the treatment of insulin resistance in obese post-menopausal women.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Dry Needle | Experimental | Other: Dry Needle, Other: abdominal exercises, and medical standard care for insulin resistance26 patients who were treated with Dry Needling (three times /week/4 months), abdominal exercises, and medical standard care for insulin resistance. |
| abdominal exercises and medical standard care for insulin resistance. | Other | Other: abdominal exercises, and medical standard care for insulin resistanceWhile Group (B), 26 patients treated with abdominal exercises and medical standard care for insulin resistance. |
Who may qualify
- Ages
- 48 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- • All participants post-menopausal from at least 3 years.
Key exclusion criteria (8 listed)
- • Surgical liposuction within the last 12 months.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dry NeedleDry Needle has been used to treat obesity. Clinical research has found that it is particularly effective for abdominal fat loss.Dry needling in the abdominal region requires an in-depth understanding of the underlying anatomy due to significant safety risks. | Other | Dry Needle |
| abdominal exercises, and medical standard care for insulin resistanceTo reduce belly fat, combine core-strengthening exercises like planks, bicycle crunches, and leg raises with overall fat-burning cardio (walking, running) and a healthy diet | Other | Dry Needle, abdominal exercises and medical standard care for insulin resistance. |
Primary outcome
HOMA-IR
Time frame: 4 months
Outcome measures, HOMA-IR (Homeostasis Model Assessment) will be used to assess insulin resistance. HOMA-IR is a model of interactions between glucose and insulin dynamics that is then used to predict fasting steady-state glucose and insulin concentrations for a wide range of possible combinations of insulin resistance and β-cell function.
4 secondary outcomes
ultrasound
Time frame: 4 months
BMI by kg/m2
Time frame: 4 months
waist circumferences by tape
Time frame: 4 months
The surface under the cumulative ranking curve (SUCRA)
Time frame: 4 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jan 2026.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Shymaa Mohammed principal investigator
out patient clinic ,faculty of physical therapy ,Cairo university ,Cairo,Egypt
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dry Needle in people with Insulin Resistance-abdominal Fats -Post Menopausal Women, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
HOMA-IR (time frame: 4 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jan 2026.