Neuraxial BlocksNCT07367386
Impact of Increasing BMI on the Success of Neuraxial Blocks in Class III Obese Parturients
An observational study of Neuraxial Blocks, run by Mariah Arif at 1 site in Qatar.
Trial summary
This study seeks to compare the success rates, feto-maternal outcomes, and complications associated with different neuraxial blocks in Class III obese parturient undergoing cesarean section Read more about this study
- Who is it for?
- Ages 18 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Neuraxial Blocks
- What is being tested?
- Neuraxial anesthesia
- Type of treatment
- Surgery or procedure
- How many people
- 1,917 participants
- Where
- 1 siteQatar
- Study dates
- 2 Feb 2025to 1 Jan 2026
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: Class III Obese parturients undergoing C-section under neuraxial blocks in the operating rooms of Women's Wellness and Research Center from 1 January 2025 to 1 December 2024.
Who may be able to join
- Age > or equal to 18 years
- BMI ≥ 45 kg/m²
- Gestational age ≥ 28 weeks
Who cannot join
- Age < 18 years
- BMI < 45 kg/m²
- History of venous thromboembolism or arterial disease (e.g., DVT, PE, angina, MI, or stroke)
- Severe active lung, cardiovascular, renal, or liver disorders; autoimmune disease; or hemoglobinopathies
- Hereditary or acquired thrombophilia (e.g., Factor V Leiden mutation or antithrombin deficiency)
- In utero fetal demise (IUFD)
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- Failed operative vaginal delivery
- Cesarean for the second twin or multiple pregnancies (triplets or higher)
- IVF pregnancy
- Intraoperative bleeding>1500mL
- Emergency cesarean section (Category I)
- Presence of large uterine fibroid ≥10 cm
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Evaluating the Impact of Increasing BMI on the Success of Neuraxial Blocks in Class III Obese Parturients: A Retrospective Cohort Study
This study seeks to compare the success rates, feto-maternal outcomes, and complications associated with different neuraxial blocks in Class III obese parturient undergoing cesarean section
Read the detailed description
This was a retrospective cohort study. The data was obtained from electronic medical records of the eligible participants.
- Conditions
- Neuraxial Blocks
- Being tested
- Neuraxial anesthesia
- Keywords
- Neuraxial blocks, Obesity, Parturient, Cesarean
- Medical subject headings
- Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Neuraxial anesthesiaProcedure or surgery
Single-shot spinal anesthesia
Neuraxial anesthesiaProcedure or surgery
Epidural anesthesia
Neuraxial anesthesiaProcedure or surgery
Combined spinal-epidural anesthesia
| Study group | Role | What they receive |
|---|---|---|
| Class III obese parturient | Class III obese parturient undergoing cesarean section under neuraxial block Receives: Procedure: Neuraxial anesthesia |
What is being measured
The primary outcome is the main question the study is designed to answer.
Failed neuraxial block
Determine the occurrence of the conversion to general anesthesia
Measured: From onset of block until surgery completion
Secondary outcomes (2)
Maternal adverse events
Determine the incidence of maternal hypotension, bradycardia, high-spinal (above T1 level), level of blockade higher than T4, post-dural puncture headache
Measured: From onset of blockade until surgery completion
Fetal outcomes
Apgar score
Measured: At one and five minutes after birth
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jan 2026
- Study start2 Feb 2025
- Primary completion31 Dec 2025
- Study completion1 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Neuraxial BlocksStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 1,917 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mariah Arif
- Sponsor type
- Other government
- Responsible party
- Sponsor-investigator, Mariah Arif, Hamad General Hospital
- Investigators
- Ayten Saracoglu, Principal investigator, University of Florida, UF Health, Jacksonville, FL 32209, USA
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07367386
- Sponsor's protocol ID
- MRC-01-24-905
- Status last verified
- Jan 2026
- First submitted
- 16 Jan 2026
- Last updated
- 27 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No