Pain ManagementLASERBFNCT07369843
LASER Effects Blood Flow
A study testing physical therapy (low power LASER) in people with Pain Management, run by Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres.
Trial summary
This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone. Study will recruit healthy volunteers and non-invasively monitor their electrocardiogram and digital pulse in response to LPL. Read more about this study
- Who is it for?
- Ages 20 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Pain Management
- What is being tested?
- physical therapy (low power LASER)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- No sites listed yet
- Study dates
- 1 Mar 2026to 30 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- age from 20-45
Who cannot join
- no medical history of diabetes, hypertension, or other medical problem
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Tzer-Bin Lin, Ph.D. contact
About this study
Official title: Effects of Low Power LASER on the Heart Rate Variability of Human Subjects
This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.
Study will recruit healthy volunteers and non-invasively monitor their electrocardiogram and digital pulse in response to LPL.
In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel)
Read the detailed description
This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.
Study will recruit healthy volunteers (age 20-60; having no diabetes, hypertension, or other medical problem) and non-invasively monitor their electrocardiogram and digital pulse in response to LPL (with an intensity for relieving pain).
In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel) at the site 2 cm distal to the applying site.
- Conditions
- Pain Management
- Being tested
- physical therapy (low power LASER)
- Keywords
- low power LASER, Heart rate, autonomic tone
- Medical subject headings
- Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
physical therapy (low power LASER)Other
Low power laser with an intensity for pain relieving will be applied to volunteers
| Study group | Role | What they receive |
|---|---|---|
| test effect | Experimental | Control, experiment, and recovery data will be acquired for each volunteer Receives: Other: physical therapy (low power LASER) |
What is being measured
The primary outcome is the main question the study is designed to answer.
heart rate
the heart rate before, during, and after low power LASER
Measured: Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2026
- Study start1 Mar 2026 (estimated)
- Primary completion30 May 2026 (estimated)
- Study completion30 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pain ManagementStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07369843
- Sponsor's protocol ID
- LASERBF1
- Other IDs
- Saint Paul's Hospital
- Acronym
- LASERBF
- Status last verified
- Jul 2025
- First submitted
- 26 Sep 2025
- Last updated
- 27 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Low Power LASER on the Heart Rate Variability of Human Subjects
- ClinicalTrials.gov ID
- NCT07369843
- Acronym / sponsor ID
- LASERBF / LASERBF1
- Conditions
- Pain Management
- Keywords
- low power LASER, Heart rate, autonomic tone
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De ChartresUniversity, hospital or other
- Study start
- 1 Mar 2026 (estimated)
- Primary completion
- 30 May 2026 (estimated)
- Study completion
- 30 May 2026 (estimated)
- First posted
- 27 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.
Study will recruit healthy volunteers and non-invasively monitor their electrocardiogram and digital pulse in response to LPL.
In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel)
Detailed description
This study investigate the potential impact of low power laser (LPL), an non-invasive physical therapy, on the cardiovascular system by focusing on its effect on heart rate and autonomic tone.
Study will recruit healthy volunteers (age 20-60; having no diabetes, hypertension, or other medical problem) and non-invasively monitor their electrocardiogram and digital pulse in response to LPL (with an intensity for relieving pain).
In addition, the potential involvement of autonomic tone will be clarify by topically applying gel (2% lidocaine gel) at the site 2 cm distal to the applying site.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| test effect | Experimental | Other: physical therapy (low power LASER)Control, experiment, and recovery data will be acquired for each volunteer |
Who may qualify
- Ages
- 20 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- age from 20-45
Key exclusion criteria (1 listed)
- no medical history of diabetes, hypertension, or other medical problem
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| physical therapy (low power LASER)Low power laser with an intensity for pain relieving will be applied to volunteers | Other | test effect |
Primary outcome
heart rate
Time frame: Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.
the heart rate before, during, and after low power LASER
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Tzer-Bin Lin, Ph.D. contact
Questions about this trial
What is this clinical trial studying?
A study testing physical therapy (low power LASER) in people with Pain Management, run by Saint Paul's Hospital, Congregation Of The Sisters Of Saint Paul De Chartres.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 27 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Chun-Ming Hsieh, MS (+886-(03)361-3141 ext. 8714, tblin2@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
heart rate (time frame: Continuous heart rate (HR) recording will start when it is stable after a brief resting (10 min); maintained during stimulation (30 min), and lasted for a period until the HR recovers.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Jan 2026; AzTrials last refreshed its copy on 27 Oct 2026.