Temporomandibular Disorders (TMD)NCT07371195
Relationship Between Upper Cervical Mobility and Temporomandibular Joint Range of Motion in Patients With Temporomandibular Disorders
An observational study of Temporomandibular Disorders (TMD) and Temporomandibular Joint Dysfunction Syndrome, run by Deraya University at 1 site in Egypt.
Trial summary
Upper cervical spine mobility plays a crucial role in temporomandibular joint (TMJ) function. This observational study investigates the relationship between upper cervical spine mobility and TMJ range of motion in patients diagnosed with temporomandibular disorders (TMD). Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Temporomandibular Disorders (TMD), Temporomandibular Joint Dysfunction Syndrome, Cervicogenic Headache
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Feb 2026to 20 Aug 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Study population: Participants will be adult patients (both male and female) aged 18 to 50 years who have been clinically diagnosed with temporomandibular joint (TMJ) dysfunction for more than three months. All participants will be recruited from the outpatient clinic of the Faculty of Physical Therapy, Deraya University, Minya, Egypt. Eligible participants will be medically stable and free from systemic or neurological disorders that could affect cervical or temporomandibular mobility.
Who may be able to join
- Medically stable individuals who consent to participate in the study.
- Age between 18 and 50 years.
- Both male and female participants.
- Patients diagnosed with temporomandibular joint (TMJ) dysfunction for at least three months.
Who cannot join
- Presence of systemic diseases.
- Body mass index (BMI) greater than 30 kg/m².
- Pregnancy.
- Recent physical therapy for cervical spine disorders, headaches, or temporomandibular dysfunction.
- Cervical radiculopathy or other neurological disorders.
- History of trauma or major psychological problems.
- Generalized joint hypermobility.
- Down syndrome.
Trial locations and contacts
1 site in 1 country.
Egypt1 site
faculty of physical therapy, Deraya University
Minya, Menia Governorate
About this study
Upper cervical spine mobility plays a crucial role in temporomandibular joint (TMJ) function. This observational study investigates the relationship between upper cervical spine mobility and TMJ range of motion in patients diagnosed with temporomandibular disorders (TMD). Cervical hypomobility may restrict mandibular movement and contribute to TMJ dysfunction through shared biomechanical and neuromuscular mechanisms.
Read the detailed description
Temporomandibular disorders (TMD) are multifactorial conditions involving the temporomandibular joint, masticatory muscles, or both. Prior research indicates a strong association between TMD and cervical spine dysfunction, with patients frequently exhibiting neck pain, reduced cervical motion, and muscular tenderness.
This study explores how upper cervical mobility (flexion, extension, and rotation) correlates with TMJ range of motion (mouth opening, lateral excursion, and protrusion). The aim is to identify whether cervical spine hypomobility contributes to restricted jaw movement in TMD patients.
A total of 50 participants with TMD will undergo standardized clinical measurements of cervical mobility using a CROM device and TMJ motion using a ruler or caliper. Pearson or Spearman correlation coefficients will be applied to evaluate the association between cervical and TMJ movement parameters.
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Joint Dysfunction Syndrome, Cervicogenic Headache
- Keywords
- Temporomandibular Joint, Temporomandibular Disorders, Upper Cervical Spine, Cervical Mobility
- Medical subject headings
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Post-Traumatic Headache
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Temporomandibular Disorder Group | Fifty patients with temporomandibular disorder will undergo evaluation of upper cervical spine mobility (flexion, extension, and rotation) and TMJ range of motion (opening, lateral excursion, and protrusion) using standardized instruments (CROM device and ruler/caliper). |
What is being measured
The primary outcome is the main question the study is designed to answer.
Upper Cervical Spine Mobility
Upper cervical spine mobility (flexion, extension, and left and right rotation) will be measured in degrees using a CROM device. Participants will be seated in an upright position, and each movement will be measured twice following standardized procedures. The mean value of both readings will be used for analysis.
Measured: Single assessment session (baseline only)
Temporomandibular Joint Range of Motion (TMJ ROM)
TMJ range of motion will be measured in millimetres using a standard ruler or digital calliper. Measurements include maximum mouth opening, lateral excursion (left and right), and protrusion. Each measurement will be taken twice, and the average will be recorded in millimetres to ensure reliability.
Measured: Single assessment session (baseline only)
Correlation Between Upper Cervical Mobility and TMJ Range of Motion
The relationship between upper cervical spine mobility (measured in degrees using the CROM device) and TMJ range of motion (measured in millimetres using a ruler or calliper) will be analysed statistically. Pearson or Spearman correlation coefficients will be applied, depending on data normality, to determine the strength and direction of association.
Measured: Single assessment session (baseline only)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2026
- Study start15 Feb 2026
- Primary completion15 Aug 2026
- Study completion20 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Temporomandibular Disorders (TMD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Deraya University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07371195
- Sponsor's protocol ID
- Upper Cervical Mobility
- Status last verified
- Aug 2026
- First submitted
- 19 Jan 2026
- Last updated
- 28 Aug 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship Between Upper Cervical Mobility and Temporomandibular Joint Range of Motion in Patients With Temporomandibular Disorders
- ClinicalTrials.gov ID
- NCT07371195
- Acronym / sponsor ID
- Upper Cervical Mobility
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Joint Dysfunction Syndrome, Cervicogenic Headache
- Keywords
- Temporomandibular Joint, Temporomandibular Disorders, Upper Cervical Spine, Cervical Mobility
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Deraya UniversityUniversity, hospital or other
- Study start
- 15 Feb 2026 (actual)
- Primary completion
- 15 Aug 2026 (actual)
- Study completion
- 20 Aug 2026 (actual)
- First posted
- 27 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Upper cervical spine mobility plays a crucial role in temporomandibular joint (TMJ) function. This observational study investigates the relationship between upper cervical spine mobility and TMJ range of motion in patients diagnosed with temporomandibular disorders (TMD). Cervical hypomobility may restrict mandibular movement and contribute to TMJ dysfunction through shared biomechanical and neuromuscular mechanisms.
Detailed description
Temporomandibular disorders (TMD) are multifactorial conditions involving the temporomandibular joint, masticatory muscles, or both. Prior research indicates a strong association between TMD and cervical spine dysfunction, with patients frequently exhibiting neck pain, reduced cervical motion, and muscular tenderness.
This study explores how upper cervical mobility (flexion, extension, and rotation) correlates with TMJ range of motion (mouth opening, lateral excursion, and protrusion). The aim is to identify whether cervical spine hypomobility contributes to restricted jaw movement in TMD patients.
A total of 50 participants with TMD will undergo standardized clinical measurements of cervical mobility using a CROM device and TMJ motion using a ruler or caliper. Pearson or Spearman correlation coefficients will be applied to evaluate the association between cervical and TMJ movement parameters.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Temporomandibular Disorder Group | – | –Fifty patients with temporomandibular disorder will undergo evaluation of upper cervical spine mobility (flexion, extension, and rotation) and TMJ range of motion (opening, lateral excursion, and protrusion) using standardized instruments (CROM device and ruler/caliper). |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Participants will be adult patients (both male and female) aged 18 to 50 years who have been clinically diagnosed with temporomandibular joint (TMJ) dysfunction for more than three months. All participants will be recruited from the outpatient clinic of the Faculty of Physical Therapy, Deraya University, Minya, Egypt. Eligible participants will be medically stable and free from systemic or neurological disorders that could affect cervical or temporomandibular mobility.
Key inclusion criteria (4 listed)
- Medically stable individuals who consent to participate in the study.
- Age between 18 and 50 years.
- Both male and female participants.
- Patients diagnosed with temporomandibular joint (TMJ) dysfunction for at least three months.
Key exclusion criteria (8 listed)
- Presence of systemic diseases.
- Body mass index (BMI) greater than 30 kg/m².
- Pregnancy.
- Recent physical therapy for cervical spine disorders, headaches, or temporomandibular dysfunction.
- Cervical radiculopathy or other neurological disorders.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Upper Cervical Spine Mobility
Time frame: Single assessment session (baseline only)
Upper cervical spine mobility (flexion, extension, and left and right rotation) will be measured in degrees using a CROM device. Participants will be seated in an upright position, and each movement will be measured twice following standardized procedures. The mean value of both readings will be used for analysis.
Temporomandibular Joint Range of Motion (TMJ ROM)
Time frame: Single assessment session (baseline only)
TMJ range of motion will be measured in millimetres using a standard ruler or digital calliper. Measurements include maximum mouth opening, lateral excursion (left and right), and protrusion. Each measurement will be taken twice, and the average will be recorded in millimetres to ensure reliability.
Correlation Between Upper Cervical Mobility and TMJ Range of Motion
Time frame: Single assessment session (baseline only)
The relationship between upper cervical spine mobility (measured in degrees using the CROM device) and TMJ range of motion (measured in millimetres using a ruler or calliper) will be analysed statistically. Pearson or Spearman correlation coefficients will be applied, depending on data normality, to determine the strength and direction of association.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Temporomandibular Disorders (TMD) and Temporomandibular Joint Dysfunction Syndrome, run by Deraya University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Upper Cervical Spine Mobility (time frame: Single assessment session (baseline only)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Aug 2026.