Overweight and ObesityNCT07372157
Neuromuscular Balance Exercise Effects in Overweight and Obese Individuals
A study testing Aerobic and strength training and Neuromuscular balance exercises in people with Overweight and Obesity, run by Marmara University at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled study aims to evaluate the effects of adding neuromuscular balance exercises to exercise programs on functional capacity, balance, and physical fitness in individuals with obesity. Read more about this study
- Who is it for?
- Ages 18 to 65 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Overweight and Obesity
- What is being tested?
- Aerobic and strength training and Neuromuscular balance exercises
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Jun 2025to Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Volunteering to participate in the study
- Having a BMI of 25-35 kg/m2
- Not having undergone any surgical operation in the last 6 months
Who cannot join
- Any musculoskeletal disorder or systemic disease that would prevent exercise
- Balance problems due to any disease that could prevent exercise
- Psychiatric or neurological disease affecting cooperation and cognitive functions
- Acute pain for any reason
- Chest pain
- History of myocardial infarction within the last year
- Congestive heart failure
- Patient's inability to adhere to treatment
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Fatih Sultan Mehmet Training and Research Hospital, Diabetes and Obesity Treatment Center
Istanbul, Istanbul, 34672
Özden Ezgi E Üner, MD, +905323072789
About this study
Official title: Investigation of the Effectiveness of Neuromuscular Control-Based Exercises Combined With Aerobic and Strength Training Exercises on Balance in Overweight and Obese Individuals
This randomized controlled study aims to evaluate the effects of adding neuromuscular balance exercises to exercise programs on functional capacity, balance, and physical fitness in individuals with obesity. Forty participants will be randomly assigned to either a control group receiving aerobic and strength training exercises or an intervention group receiving aerobic and strength training combined with neuromuscular balance exercises. Both exercise programs will be conducted three times per week for eight weeks. Functional capacity, balance, and physical fitness outcomes will be assessed at baseline and after the intervention period. The findings are expected to contribute to the integration of balance-focused exercises into rehabilitation programs for individuals with obesity.
Read the detailed description
This project will begin with initial assessments of volunteers to examine the effects of balance exercises on postural control and neuromuscular connections in obesity treatment. A multimodal exercise program (neuromuscular balance exercises, aerobic training, and resistance training) will be designed for individuals with obesity, and its effects on physical function, balance impairment, and weight management will be evaluated. In the first phase, participants' static and dynamic balance will be analyzed using clinical scales. In the second phase, an 8-week multimodal exercise program will be implemented, and the outcomes will be comparatively examined in relation to the weight loss process.
The study aims to provide scientific data to support the individualization of exercise programs by examining postural balance adaptations in response to changes in body composition during weight loss. The findings are expected to contribute to more comprehensive physical activity approaches in obesity management and to guide clinical applications.
This study adds a different perspective by evaluating the functional benefits of neuromuscular-based balance exercises in addition to traditional aerobic and strength training exercises. The assessment, conducted in individuals with obesity who have experienced weight loss, is expected to provide important findings for the interpretation and discussion of outcomes.
- Conditions
- Overweight and Obesity
- Being tested
- Aerobic and strength training, Neuromuscular balance exercises
- Keywords
- Obesity, Exercise, Neuromuscular control, Quality of life, Postural stability
- Medical subject headings
- Overweight, Obesity, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Aerobic and strength trainingBehavioural
The aerobic and strength training program consists of supervised exercise sessions performed three days per week for eight weeks. Aerobic exercises are conducted at a moderate intensity, and strength training targets major muscle groups using body weight and resistance-based exercises. Each session is structured to include warm-up, main exercise components, and cool-down phases.
Neuromuscular balance exercisesBehavioural
Neuromuscular balance exercises are added to the standard exercise program and are designed to improve postural control and balance. The exercises include progressive static and dynamic balance tasks and are performed three times per week for eight weeks under supervision.
| Study group | Role | What they receive |
|---|---|---|
| Control group | Active comparator | Participants in the control group are individuals with obesity or overweight who receive a standardized exercise program that includes aerobic and strength training exercises. The program is performed three times per week over an eight-week period. Receives: Behavioral: Aerobic and strength training |
| Intervention group | Experimental | Participants in the intervention group consist of individuals with obesity or overweight who receive the same aerobic and strength training program as the control group, with the addition of neuromuscular balance exercises. The intervention is performed three times per week for eight weeks. Receives: Behavioral: Aerobic and strength training; Behavioral: Neuromuscular balance exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Dynamic Balance Performance (Four Step Square Test)
Dynamic balance will be assessed using the Four Step Square Test, which measures the time (in seconds) required to complete a multidirectional stepping sequence.
Measured: Baseline, at the 4th weeks and at the end of 8 weeks
Postural Control (Functional Reach Test)
Postural control will be evaluated using the Functional Reach Test, which measures the maximal forward reach distance (in centimeters) while maintaining a fixed base of support.
Measured: Baseline, Week 4, and Week 8
Walking Endurance (2-Minute Walk Test)
Walking endurance will be assessed using the 2-Minute Walk Test, which measures the total distance walked in meters over a two-minute period.
Measured: Baseline, at the 4th weeks and at the end of 8 weeks
Lower Extremity Functional Strength (30-Second Chair Stand Test)
Lower extremity functional strength will be evaluated using the 30-Second Chair Stand Test, which measures the number of full stands completed within 30 seconds.
Measured: Baseline, Week 4, and Week 8
Secondary outcomes (1)
Health-Related Quality of Life Assessed by the Short Form-12 (SF-12)
Health-related quality of life will be evaluated using the Short Form-12 (SF-12) Health Survey, which assesses physical and mental health components.
Measured: Baseline, at the 4th weeks and at the end of 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jan 2026
- Study start15 Jun 2025
- Primary completionJun 2026 (estimated)
- Study completionJun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Overweight and ObesityStudies of the same condition, open and under way.
- More trials run by Marmara UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants are randomly assigned to either a control group or an intervention group, and both groups are followed in parallel throughout the study period.
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Marmara University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, M. Gulden Polat, Marmara University
- Investigators
- Mine Gülden G Polat, PhD, Principal investigator, Marmara University Faculty of Health Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07372157
- Sponsor's protocol ID
- 130.2024fbu
- Status last verified
- Dec 2025
- First submitted
- 18 Dec 2025
- Last updated
- 28 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared.
Study at a glance
From the registry record, last updated by the sponsor on 28 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Effectiveness of Neuromuscular Control-Based Exercises Combined With Aerobic and Strength Training Exercises on Balance in Overweight and Obese Individuals
- ClinicalTrials.gov ID
- NCT07372157
- Acronym / sponsor ID
- 130.2024fbu
- Conditions
- Overweight and Obesity
- Keywords
- Obesity, Exercise, Neuromuscular control, Quality of life, Postural stability
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Marmara UniversityUniversity, hospital or other
- Study start
- 15 Jun 2025 (actual)
- Primary completion
- Jun 2026 (estimated)
- Study completion
- Jun 2026 (estimated)
- First posted
- 28 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled study aims to evaluate the effects of adding neuromuscular balance exercises to exercise programs on functional capacity, balance, and physical fitness in individuals with obesity. Forty participants will be randomly assigned to either a control group receiving aerobic and strength training exercises or an intervention group receiving aerobic and strength training combined with neuromuscular balance exercises. Both exercise programs will be conducted three times per week for eight weeks. Functional capacity, balance, and physical fitness outcomes will be assessed at baseline and after the intervention period. The findings are expected to contribute to the integration of balance-focused exercises into rehabilitation programs for individuals with obesity.
Detailed description
This project will begin with initial assessments of volunteers to examine the effects of balance exercises on postural control and neuromuscular connections in obesity treatment. A multimodal exercise program (neuromuscular balance exercises, aerobic training, and resistance training) will be designed for individuals with obesity, and its effects on physical function, balance impairment, and weight management will be evaluated. In the first phase, participants' static and dynamic balance will be analyzed using clinical scales. In the second phase, an 8-week multimodal exercise program will be implemented, and the outcomes will be comparatively examined in relation to the weight loss process.
The study aims to provide scientific data to support the individualization of exercise programs by examining postural balance adaptations in response to changes in body composition during weight loss. The findings are expected to contribute to more comprehensive physical activity approaches in obesity management and to guide clinical applications.
This study adds a different perspective by evaluating the functional benefits of neuromuscular-based balance exercises in addition to traditional aerobic and strength training exercises. The assessment, conducted in individuals with obesity who have experienced weight loss, is expected to provide important findings for the interpretation and discussion of outcomes.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants are randomly assigned to either a control group or an intervention group, and both groups are followed in parallel throughout the study period.
| Arm | Type | Receives |
|---|---|---|
| Control group | Active comparator | Behavioral: Aerobic and strength trainingParticipants in the control group are individuals with obesity or overweight who receive a standardized exercise program that includes aerobic and strength training exercises. The program is performed three times per week over an eight-week period. |
| Intervention group | Experimental | Behavioral: Aerobic and strength training, Behavioral: Neuromuscular balance exercisesParticipants in the intervention group consist of individuals with obesity or overweight who receive the same aerobic and strength training program as the control group, with the addition of neuromuscular balance exercises. The intervention is performed three times per week for eight weeks. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Volunteering to participate in the study
- Having a BMI of 25-35 kg/m2
- Not having undergone any surgical operation in the last 6 months
Key exclusion criteria (8 listed)
- Any musculoskeletal disorder or systemic disease that would prevent exercise
- Balance problems due to any disease that could prevent exercise
- Psychiatric or neurological disease affecting cooperation and cognitive functions
- Acute pain for any reason
- Chest pain
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Aerobic and strength trainingThe aerobic and strength training program consists of supervised exercise sessions performed three days per week for eight weeks. Aerobic exercises are conducted at a moderate intensity, and strength training targets major muscle groups using body weight and resistance-based exercises. Each session is structured to include warm-up, main exercise components, and cool-down phases. | Behavioural | Control group, Intervention group |
| Neuromuscular balance exercisesNeuromuscular balance exercises are added to the standard exercise program and are designed to improve postural control and balance. The exercises include progressive static and dynamic balance tasks and are performed three times per week for eight weeks under supervision. | Behavioural | Intervention group |
Primary outcome
Dynamic Balance Performance (Four Step Square Test)
Time frame: Baseline, at the 4th weeks and at the end of 8 weeks
Dynamic balance will be assessed using the Four Step Square Test, which measures the time (in seconds) required to complete a multidirectional stepping sequence.
Postural Control (Functional Reach Test)
Time frame: Baseline, Week 4, and Week 8
Postural control will be evaluated using the Functional Reach Test, which measures the maximal forward reach distance (in centimeters) while maintaining a fixed base of support.
Walking Endurance (2-Minute Walk Test)
Time frame: Baseline, at the 4th weeks and at the end of 8 weeks
Walking endurance will be assessed using the 2-Minute Walk Test, which measures the total distance walked in meters over a two-minute period.
Lower Extremity Functional Strength (30-Second Chair Stand Test)
Time frame: Baseline, Week 4, and Week 8
Lower extremity functional strength will be evaluated using the 30-Second Chair Stand Test, which measures the number of full stands completed within 30 seconds.
1 secondary outcome
Health-Related Quality of Life Assessed by the Short Form-12 (SF-12)
Time frame: Baseline, at the 4th weeks and at the end of 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Jan 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mine Gülden G Polat, PhD principal investigator
Marmara University Faculty of Health Sciences
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Aerobic and strength training and Neuromuscular balance exercises in people with Overweight and Obesity, run by Marmara University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ekin UĞUR CANÖZ, MSc (+905374525191, ekinugur@marun.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dynamic Balance Performance (Four Step Square Test) (time frame: Baseline, at the 4th weeks and at the end of 8 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jan 2026.