Inguinal Hernia RepairNCT07373314
Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia
A study testing Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group. and Conventional Laparoscopic TAPP (CL-TAPP) in people with Inguinal Hernia Repair, run by University of Health Sciences Lahore.
Trial summary
This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). Read more about this study
- Who is it for?
- Ages 18 to 50 years
- Conditions the study is for
- Inguinal Hernia Repair
- What is being tested?
- Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group. and Conventional Laparoscopic TAPP (CL-TAPP)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- No sites listed yet
- Study dates
- 10 Feb 2026to 30 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age: 18 to 50 years.
- Gender: Both male and female participants.
- Condition: Diagnosed with unilateral inguinal hernia (as per operational definition).
- Health Status: ASA I-III (American Society of Anesthesiologists physical status classification), indicating that the patient is fit for surgery.
- Consent: Participants must be able to provide informed consent to participate in the study.
Who cannot join
- Femoral Hernias.
- Incarcerated or Strangulated Hernia.
- Recurrent Hernias (as per medical record).
- Serious Systemic Diseases:
- Conditions such as heart failure or coagulation problems (e.g., PT > 15 sec).
- ASA III-V classification, indicating a higher risk for surgery.
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- Pregnancy (if applicable).
- Allergy to Anesthesia or the substances used in the tumescent solution (lidocaine, epinephrine, saline).
- Uncontrolled Diabetes or other medical conditions that might interfere with the healing process.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: A Randomized Controlled Trial Comparing Modified Tumescent vs. Conventional Laparoscopic TAPP for Inguinal Hernia Repair
This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.
- Conditions
- Inguinal Hernia Repair
- Being tested
- Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group., Conventional Laparoscopic TAPP (CL-TAPP)
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group.Other
In this intervention, participants will undergo laparoscopic inguinal hernia repair using the modified tumescent technique. This technique involves pre-peritoneal infiltration of a solution containing lidocaine, epinephrine, and saline. The tumescent solution is injected into the peritoneum to create a "tumescent" effect, making the tissues easier to dissect and reducing bleeding. This approach aims to improve surgical visibility, reduce operative time, minimize postoperative pain, and shorten the learning curve for less experienced surgeons. The rest of the procedure follows the standard laparoscopic TAPP repair, with mesh placement and peritoneal closure.
Conventional Laparoscopic TAPP (CL-TAPP)Other
In this intervention, participants will undergo the conventional laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This standard technique involves placing three ports to access the inguinal region, followed by dissection of the pre-peritoneal space and placement of a mesh to repair the hernia. The conventional method does not use tumescent infiltration and relies solely on the surgeon's skill to navigate the anatomical structures. This approach is well-established and commonly used in inguinal hernia repairs, but it may be associated with longer operative times and more postoperative pain compared to the modified technique.
| Study group | Role | What they receive |
|---|---|---|
| Modified Tumescent Laparoscopic TAPP (MT-TAPP) | Experimental | Not described Receives: Other: Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group. |
| Conventional Laparoscopic TAPP (CL-TAPP) | Active comparator | Not described Receives: Other: Conventional Laparoscopic TAPP (CL-TAPP) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Score
A score of 0 represents no pain, while a score of 10 represents the worst pain.
Measured: Recorded 24 hours post-surgery.
Seroma Formation:
Measured: Presence or absence of seroma, assessed during the 7-day postoperative follow-up.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jan 2026
- Study start10 Feb 2026 (estimated)
- Primary completion15 Aug 2026 (estimated)
- Study completion30 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Inguinal Hernia RepairStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Health Sciences Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Taseen Imran, University of Health Sciences Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07373314
- Sponsor's protocol ID
- Exp132
- Status last verified
- Jan 2026
- First submitted
- 13 Jan 2026
- Last updated
- 28 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized Controlled Trial Comparing Modified Tumescent vs. Conventional Laparoscopic TAPP for Inguinal Hernia Repair
- ClinicalTrials.gov ID
- NCT07373314
- Acronym / sponsor ID
- Exp132
- Conditions
- Inguinal Hernia Repair
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- University of Health Sciences LahoreUniversity, hospital or other
- Study start
- 10 Feb 2026 (estimated)
- Primary completion
- 15 Aug 2026 (estimated)
- Study completion
- 30 Aug 2026 (estimated)
- First posted
- 28 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP). The primary goal is to determine which technique provides better outcomes in terms of operative time, ease of pre-peritoneal space dissection, postoperative pain, and the formation of seromas. The study will involve 60 patients diagnosed with unilateral inguinal hernias, randomly assigned to either group. Participants in Group A will undergo the MT-TAPP procedure, which involves pre-peritoneal infiltration of a local anesthetic solution to improve dissection and reduce pain. Group B will undergo the standard CL-TAPP procedure. Data will be collected on various outcome measures and analyzed to identify which technique leads to quicker recovery, less postoperative pain, and fewer complications. The results of this study will help guide surgical decisions and improve patient outcomes in inguinal hernia repair.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Modified Tumescent Laparoscopic TAPP (MT-TAPP) | Experimental | Other: Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group. |
| Conventional Laparoscopic TAPP (CL-TAPP) | Active comparator | Other: Conventional Laparoscopic TAPP (CL-TAPP) |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age: 18 to 50 years.
- Gender: Both male and female participants.
- Condition: Diagnosed with unilateral inguinal hernia (as per operational definition).
- Health Status: ASA I-III (American Society of Anesthesiologists physical status classification), indicating that the patient is fit for surgery.
- Consent: Participants must be able to provide informed consent to participate in the study.
Key exclusion criteria (9 listed)
- Femoral Hernias.
- Incarcerated or Strangulated Hernia.
- Recurrent Hernias (as per medical record).
- Serious Systemic Diseases:
- Conditions such as heart failure or coagulation problems (e.g., PT > 15 sec).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group.In this intervention, participants will undergo laparoscopic inguinal hernia repair using the modified tumescent technique. This technique involves pre-peritoneal infiltration of a solution containing lidocaine, epinephrine, and saline. The tumescent solution is injected into the peritoneum to create a "tumescent" effect, making the tissues easier to dissect and reducing bleeding. This approach aims to improve surgical visibility, reduce operative time, minimize postoperative pain, and shorten the learning curve for less experienced surgeons. The rest of the procedure follows the standard laparoscopic TAPP repair, with mesh placement and peritoneal closure. | Other | Modified Tumescent Laparoscopic TAPP (MT-TAPP) |
| Conventional Laparoscopic TAPP (CL-TAPP)In this intervention, participants will undergo the conventional laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This standard technique involves placing three ports to access the inguinal region, followed by dissection of the pre-peritoneal space and placement of a mesh to repair the hernia. The conventional method does not use tumescent infiltration and relies solely on the surgeon's skill to navigate the anatomical structures. This approach is well-established and commonly used in inguinal hernia repairs, but it may be associated with longer operative times and more postoperative pain compared to the modified technique. | Other | Conventional Laparoscopic TAPP (CL-TAPP) |
Primary outcome
Pain Score
Time frame: Recorded 24 hours post-surgery.
A score of 0 represents no pain, while a score of 10 represents the worst pain.
Seroma Formation:
Time frame: Presence or absence of seroma, assessed during the 7-day postoperative follow-up.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group. and Conventional Laparoscopic TAPP (CL-TAPP) in people with Inguinal Hernia Repair, run by University of Health Sciences Lahore.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 28 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Dr. Taseen Imran (923045079008, taseenimran5@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Score (time frame: Recorded 24 hours post-surgery.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jan 2026.