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Healthy AdultISACNCT07376551

Isokinetic Strength and Anaerobic Capacity

An observational study of Healthy Adult and Physical Condition, run by Uludag University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study aims to investigate differences in isokinetic knee extensor and flexor strength parameters among recreationally active young adult males classified into low, moderate, and high anaerobic power groups based on relative peak power (W/kg) obtained from the Wingate Anaerobic Test. Read more about this study

Who is it for?
Ages 20 to 32 years, men onlyHealthy volunteers can take part
Conditions the study is for
Healthy Adult, Physical Condition
How many people
80 participants
Where
1 siteTurkey (Türkiye)
Study dates
5 Jan 2026to 1 Mar 2026
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 32 years
  • Men only
  • Healthy volunteers accepted
  • Adult

Study population: The study population will consist of recreationally active young adult males aged 22-30 years who engage in regular physical activity at least two days per week. Participants will be non-elite individuals without a history of serious orthopedic injury within the past six months, cardiovascular or respiratory disease, or regular medication use. All participants will be healthy volunteers capable of performing maximal exercise testing and will provide written informed consent prior to participation.

Who may be able to join

  • Male participants aged between 20 and 30 years
  • Moderately physically active individuals, as defined by the International Physical Activity Questionnaire (IPAQ)
  • Apparently healthy, with no known neurological, vestibular, or musculoskeletal disorders affecting balance
  • Ability to stand independently and complete balance assessments
  • Willingness to participate and provide written informed consent

Who cannot join

  • History of lower-limb, spine, or pelvic injury or surgery within the past 6 months
  • Presence of acute or chronic pain affecting posture or balance
  • Diagnosed neurological, vestibular, or balance disorders
  • Use of medications or substances that may affect neuromuscular function or postural control
  • Participation in another clinical or observational study within the past 3 months

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site
  • Aeromedical Research And Training Center (ARTC)

    Eskişehir, 26000

Other trials in Turkey (Türkiye)

About this study

Official title: The Effect of Isokinetic Strength on Anaerobic Capacity in Recreationally Active Young Adult Males

This study aims to investigate differences in isokinetic knee extensor and flexor strength parameters among recreationally active young adult males classified into low, moderate, and high anaerobic power groups based on relative peak power (W/kg) obtained from the Wingate Anaerobic Test. Eighty male participants aged 22-30 years, engaging in regular physical activity, will undergo body composition analysis, isokinetic strength testing at 60°/s, and a 30-second Wingate test performed on separate days. Participants will be grouped according to median-based anaerobic power classification to allow meaningful group comparisons. Group differences in peak torque and total work will be analyzed using ANOVA or non-parametric equivalents, and relationships between Wingate parameters and isokinetic strength will be examined using correlation analyses. The findings are expected to provide novel insights into the relationship between anaerobic power classification and lower-extremity muscle strength profiles, contributing to performance profiling and training planning in recreationally active populations.

Read the detailed description

This study will investigate the relationship between anaerobic power classification and isokinetic lower-extremity muscle strength in recreationally active young adult males. Participants will be classified into three anaerobic power groups (low, moderate, and high) based on relative peak power (W/kg) obtained from the Wingate Anaerobic Test. This classification approach is intended to move beyond single-variable correlation analyses commonly reported in the literature and to enable meaningful group-based comparisons of muscle strength profiles.

A total of 80 male participants aged 22-30 years who engage in regular physical activity at least twice per week will be recruited. Individuals with a history of serious orthopedic injury within the past six months, cardiovascular or respiratory disease, or regular medication use will be excluded. Body composition parameters will be assessed using bioelectrical impedance analysis prior to performance testing.

Isokinetic knee extensor and flexor strength of the dominant leg will be evaluated using concentric contractions at an angular velocity of 60°/s. Peak torque and total work values will be recorded as primary isokinetic strength outcomes. Anaerobic performance will be assessed on a separate day using a 30-second Wingate Anaerobic Test performed on a cycle ergometer, during which participants will be verbally encouraged to exert maximal effort throughout the test. Relative peak power, mean power, and fatigue index values will be obtained.

Participants will be grouped according to median-based classification of relative peak power values to facilitate comparison among anaerobic power levels in a sample of limited size. Differences in isokinetic strength parameters between groups will be analyzed using one-way analysis of variance or non-parametric equivalents when appropriate. Associations between Wingate-derived anaerobic parameters and isokinetic strength measures will also be examined using correlation analyses.

The results of this study are expected to clarify whether individuals with higher anaerobic power levels demonstrate superior isokinetic knee extensor and flexor strength profiles. The findings may contribute to a better understanding of the interaction between anaerobic performance capacity and lower-extremity muscle strength, with potential implications for performance profiling, training program design, and exercise-based rehabilitation strategies in recreationally active populations.

Keywords
Physical Fitness, Exercise Test, Acute Exercise

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT07376551
Study groupRoleWhat they receive
Low Anaerobic Power (LAP)Participants are recreationally active young adult males classified into three cohorts based on relative peak power (W/kg) obtained from the Wingate Anaerobic Test. The low, moderate, and high anaerobic power groups represent individuals with differing anaerobic performance capacities derived from median-based classification. All participants are physically active but non-elite, with no recent history of orthopedic injury or cardiopulmonary disease. Comparisons among cohorts are conducted to examine differences in isokinetic knee extensor and flexor strength parameters.
Moderate Anaerobic Power (MAP)Participants are recreationally active young adult males classified into three cohorts based on relative peak power (W/kg) obtained from the Wingate Anaerobic Test. The low, moderate, and high anaerobic power groups represent individuals with differing anaerobic performance capacities derived from median-based classification. All participants are physically active but non-elite, with no recent history of orthopedic injury or cardiopulmonary disease. Comparisons among cohorts are conducted to examine differences in isokinetic knee extensor and flexor strength parameters.
High Anaerobic Power (HAP)Participants are recreationally active young adult males classified into three cohorts based on relative peak power (W/kg) obtained from the Wingate Anaerobic Test. The low, moderate, and high anaerobic power groups represent individuals with differing anaerobic performance capacities derived from median-based classification. All participants are physically active but non-elite, with no recent history of orthopedic injury or cardiopulmonary disease. Comparisons among cohorts are conducted to examine differences in isokinetic knee extensor and flexor strength parameters.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Isokinetic knee extensor and flexor peak torque (Nm) at 60°/s

    Peak torque values of the knee extensor and flexor muscles will be assessed using isokinetic dynamometry during concentric contractions at an angular velocity of 60°/s. Measurements will be obtained from the dominant leg following a standardized warm-up protocol. Peak torque (Nm) will be used as the primary indicator of maximal dynamic muscle strength.

    Measured: day 1 (Assessed during a single laboratory testing session.)

Secondary outcomes (1)
  1. Wingate-derived anaerobic performance parameters

    Anaerobic performance will be assessed using the 30-second Wingate Anaerobic Test performed on a cycle ergometer. Relative peak power (W/kg) will be used.

    Measured: day 1 (Assessed during a single laboratory testing session.)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted29 Jan 2026
  2. Study start5 Jan 2026
  3. Primary completion1 Mar 2026
  4. Study completion1 Mar 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Case crossover
Time perspective
Prospective
Enrolment
80 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07376551
Sponsor's protocol ID
E-87914409-050.04-117159
Acronym
ISAC
Status last verified
Jan 2026
First submitted
9 Jan 2026
Last updated
9 Jun 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: This observational study will follow a cross-sectional group comparison design. Eligible participants will undergo body composition assessment, isokinetic knee extensor and flexor strength testing, and a 30-second Wingate Anaerobic Test conducted on separate days. Based on relative peak power (W/kg) derived from the Wingate test, participants will be classified into low, moderate, and high anaerobic power groups. Isokinetic strength parameters will be compared across groups, and associations between anaerobic performance and muscle strength measures will be analyzed to address the study objectives.

Publications

  • Bar-Or O. The Wingate anaerobic test. An update on methodology, reliability and validity. Sports Med. 1987 Nov-Dec;4(6):381-94. doi: 10.2165/00007256-198704060-00001. No abstract available.

    PubMed 3324256
  • Zupan MF, Arata AW, Dawson LH, Wile AL, Payn TL, Hannon ME. Wingate Anaerobic Test peak power and anaerobic capacity classifications for men and women intercollegiate athletes. J Strength Cond Res. 2009 Dec;23(9):2598-604. doi: 10.1519/JSC.0b013e3181b1b21b.

    PubMed 19910814
  • Park JH, Kim JE, Yoo JI, Kim YP, Kim EH, Seo TB. Comparison of maximum muscle strength and isokinetic knee and core muscle functions according to pedaling power difference of racing cyclist candidates. J Exerc Rehabil. 2019 Jun 30;15(3):401-406. doi: 10.12965/jer.1938180.090. eCollection 2019 Jun.

    PubMed 31316932
  • 1.Alemdaroğlu, U. (2012). The Relationship Between Muscle Strength, Anaerobic Performance, Sprinting Ability, Agility and Vertical Jump Performance. Journal of Strength and Conditioning Research. 2. Bar Or, O. (1987). The Wingate anaerobic test: an update on methodology, reliability, and validity. Sports Medicine, 4(6), 381-394. (aracı olarak anılmış çalışmalarda referans). 3. Castaneda, A., Inbar, O., Bar Or, O. vd. (2021). The Wingate Anaerobic Test: A Narrative Review of the Protocol Variables that Affect the Results Obtained. Applied Sciences, 11(16), 7417. 4. Comin, A. C., vd. (2011). Validity of the Wingate Anaerobic Test for the Evaluation of Anaerobic Power and Capacity. Journal of Strength & Conditioning Research. (Özet referans) 5. Evans, E. M., & Quinney, H. A. (2003). Wingate Anaerobic Test peak power and anaerobic capacity classification system in NCAA athletes. Journal of Strength and Conditioning Research. 6. Harbili, S. (2015). Relationship between lower extremity isokinetic strength and anaerobic power in weightlifters, basketball and soccer players. International Education Studies. 7. Harbili, S. (2022). Comparison of bilateral isokinetic and isometric strength of knee extensor and flexor muscles. European Journal of Exercise & Rehabilitation. 8. Kin İsler, A., vd. (2008). The relationship between anaerobic performance, muscle strength and sprinting ability. International Education Studies. 9. Kavaliauskas, M., & Phillips, S. M. (2016). Reliability and sensitivity of the 6 and 30 second Wingate tests in physically active males and females. Isokinetics and Exercise Science, 24(4), 277-284. 10. Park, J., vd. (2019). Comparison of maximum muscle strength and isokinetic muscle functions according to pedaling power. PMC. 11. Zagatto, A. M., Beck, W. R., & Gobatto, C. A. (2009). Validity of the Running Anaerobic Sprint Test (RAST) for assessing anaerobic power and predicting short-distance performances. Journal of Strength and Conditioning Research, 23(6), 1820-1827. https://doi.org/10.1519/JSC.0b013e3181b3df32 12. Lehance, C., et al. (2009). Muscular strength, functional performances and injury risk in soccer players. Scandinavian Journal of Medicine & Science in Sports. 13. Castaneda, A., vd. (2021). The Wingate Anaerobic Test: A Narrative Review.

Questions about this trial

What is this clinical trial studying?

An observational study of Healthy Adult and Physical Condition, run by Uludag University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 9 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Isokinetic knee extensor and flexor peak torque (Nm) at 60°/s (time frame: day 1 (Assessed during a single laboratory testing session.)). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07376551, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jun 2026.

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