Cannabis UserRecalibrateNCT07379736
Online Brief Advice Intervention for Heavy Cannabis Users
A study testing Educational video and Relaxation video in people with Cannabis User, run by King's College London at 1 site in United Kingdom.
Trial summary
This project will evaluate whether a brief online intervention focused on cannabis withdrawal can increase awareness and insight about cannabis use disorder among daily cannabis users. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cannabis User
- What is being tested?
- Educational video and Relaxation video
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 16 Oct 2025to Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adults (>18 years)
- Daily/near daily cannabis users (25+ days/month, min. 3.5g/week)
- Sufficiently fluent in English
Who cannot join
- Participant is prescribed medical cannabis by a healthcare professional
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site, 1 recruiting
- Recruiting
Denmark Hill
London, Greater London, SE5 9RS
Catherine Sadler, 07902099721, catherine.sadler@kcl.ac.uk
About this study
Official title: Randomised-Controlled Trial of an Online Brief Advice Intervention for Heavy Cannabis Users (RECALIBRATE)
This project will evaluate whether a brief online intervention focused on cannabis withdrawal can increase awareness and insight about cannabis use disorder among daily cannabis users. The study will employ a randomised controlled trial design comparing an intervention consisting of a short educational video on cannabis withdrawal and personalised feedback on the Cannabis Withdrawal Scale, against a control condition of a relaxation video and mood questionnaire.
The investigators will aim to recruit at least 100 daily cannabis users (minimum 25 days of cannabis use /month and minimum 3.5g cannabis/week [low-medium daily use]) through Prolific, an online research participant platform. Potential participants will complete a brief screening questionnaire (1 minute) to confirm that participants meet inclusion criteria, before randomisation. The experiment will last 10-15 minutes and will include baseline demographic and substance use measures, the intervention or control condition, and outcome measures.
The primary outcome will be cannabis use awareness and insight as measured by the Substance Use Awareness and Insight Scale (SAS). Secondary outcomes will include intention to change cannabis use. This study aims to determine whether a short online intervention can increase awareness about cannabis withdrawal among heavy users. If successful, subsequent studies will be designed to assess these outcomes over the longer-term.
- Conditions
- Cannabis User
- Being tested
- Educational video, Relaxation video
- Keywords
- Cannabis, Brief Intervention
- Medical subject headings
- Marijuana Abuse
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Educational videoOther
Also called Learning video, Informational video
Short educational video on cannabis withdrawal and personalised feedback on the Cannabis Withdrawal Scale.
Relaxation videoOther
Also called Mindfulness video, Meditation video, Peaceful video
Relaxation video and mood questionnaire with personalised feedback
| Study group | Role | What they receive |
|---|---|---|
| Educational video | Experimental | A short educational video on cannabis withdrawal and personalised feedback on the Cannabis Withdrawal Scale Receives: Other: Educational video |
| Relaxation video | Active comparator | A relaxation video and mood questionnaire Receives: Other: Relaxation video |
What is being measured
The primary outcome is the main question the study is designed to answer.
Substance (cannabis) use awareness and insight scale (SAS)
Measured by the Substance Use Awareness and Insight Scale, designed to assess awareness in substance use disorder. Minimum value = 0, maximum value 70. Higher score = worse outcome, less insight and awareness.
Measured: Day 1
Secondary outcomes (1)
Intention to change cannabis use
This outcome measures participants' motivation and readiness to alter their cannabis consumption behaviours following the intervention. The Intention to Change Cannabis Use scale will be used which is adapted from Motivation to Stop Scale. Minimum score = 1, maximum score = 7. Higher score = better outcome, higher motivation to stop.
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jan 2026
- Study start16 Oct 2025
- Primary completionSep 2026 (estimated)
- Study completionSep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cannabis UserStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- King's College London
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07379736
- Sponsor's protocol ID
- REMAS: 49272
- Acronym
- Recalibrate
- Status last verified
- Oct 2025
- First submitted
- 22 Sep 2025
- Last updated
- 30 Jan 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Randomised-Controlled Trial of an Online Brief Advice Intervention for Heavy Cannabis Users (RECALIBRATE)
- ClinicalTrials.gov ID
- NCT07379736
- Acronym / sponsor ID
- Recalibrate / REMAS: 49272
- Conditions
- Cannabis User
- Keywords
- Cannabis, Brief Intervention
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- King's College LondonUniversity, hospital or other
- Study start
- 16 Oct 2025 (actual)
- Primary completion
- Sep 2026 (estimated)
- Study completion
- Sep 2026 (estimated)
- First posted
- 30 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project will evaluate whether a brief online intervention focused on cannabis withdrawal can increase awareness and insight about cannabis use disorder among daily cannabis users. The study will employ a randomised controlled trial design comparing an intervention consisting of a short educational video on cannabis withdrawal and personalised feedback on the Cannabis Withdrawal Scale, against a control condition of a relaxation video and mood questionnaire.
The investigators will aim to recruit at least 100 daily cannabis users (minimum 25 days of cannabis use /month and minimum 3.5g cannabis/week [low-medium daily use]) through Prolific, an online research participant platform. Potential participants will complete a brief screening questionnaire (1 minute) to confirm that participants meet inclusion criteria, before randomisation. The experiment will last 10-15 minutes and will include baseline demographic and substance use measures, the intervention or control condition, and outcome measures.
The primary outcome will be cannabis use awareness and insight as measured by the Substance Use Awareness and Insight Scale (SAS). Secondary outcomes will include intention to change cannabis use. This study aims to determine whether a short online intervention can increase awareness about cannabis withdrawal among heavy users. If successful, subsequent studies will be designed to assess these outcomes over the longer-term.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Educational video | Experimental | Other: Educational videoA short educational video on cannabis withdrawal and personalised feedback on the Cannabis Withdrawal Scale |
| Relaxation video | Active comparator | Other: Relaxation videoA relaxation video and mood questionnaire |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Adults (>18 years)
- Daily/near daily cannabis users (25+ days/month, min. 3.5g/week)
- Sufficiently fluent in English
Key exclusion criteria (1 listed)
- Participant is prescribed medical cannabis by a healthcare professional
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Educational videoAlso: Learning video, Informational videoShort educational video on cannabis withdrawal and personalised feedback on the Cannabis Withdrawal Scale. | Other | Educational video |
| Relaxation videoAlso: Mindfulness video, Meditation video, Peaceful videoRelaxation video and mood questionnaire with personalised feedback | Other | Relaxation video |
Primary outcome
Substance (cannabis) use awareness and insight scale (SAS)
Time frame: Day 1
Measured by the Substance Use Awareness and Insight Scale, designed to assess awareness in substance use disorder. Minimum value = 0, maximum value 70. Higher score = worse outcome, less insight and awareness.
1 secondary outcome
Intention to change cannabis use
Time frame: Day 1
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jan 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Educational video and Relaxation video in people with Cannabis User, run by King's College London at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 30 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Edward Chesney, MRCPsych (02078365454, edward.chesney@kcl.ac.uk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Substance (cannabis) use awareness and insight scale (SAS) (time frame: Day 1). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jan 2026; AzTrials last refreshed its copy on 31 Oct 2026.