AsthmaNCT07383896
Chronic Obstructive Pulmonary Disease and Asthma in Workers at Navanakorn Industrial Zone, Thailand
An observational study of Asthma and COPD, run by Thammasat University at 1 site in Thailand.
Trial summary
The goal of this observational study is to determine the prevalence of asthma and chronic obstructive pulmonary disease (COPD) among workers in an industrial zone in Thailand. The main question the study aims to answer is: What is the prevalence of asthma and COPD among workers in Thailand? Participants will complete… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- What is being tested?
- Pulmonary function test
- How many people
- 310 participants
- Where
- 1 siteThailand
- Study dates
- 1 Sep 2025to 31 May 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Subjects aged 18 years or older who work or live in the Navanakorn Industrial Zone, Thailand.
Who may be able to join
- Age 18 years or older
Who cannot join
- Inability to perform spirometry
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Thailand1 site, 1 recruiting
- Recruiting
Faculty of Medicine, Thammasat University
Pathum Thani, Changwat Pathum Thani, 12120
Narongkorn Saiphoklang, MD, +6629269794, M_narongkorn@hotmail.com
Apiwat Pugongchai, MSc, +6629269142, pu.apiwat@gmail.com
About this study
The goal of this observational study is to determine the prevalence of asthma and chronic obstructive pulmonary disease (COPD) among workers in an industrial zone in Thailand.
The main question the study aims to answer is:
What is the prevalence of asthma and COPD among workers in Thailand? Participants will complete a questionnaire on respiratory symptoms and undergo pulmonary function testing.
Read the detailed description
This study is a cross-sectional study. The study aims to determine the prevalence of asthma and COPD among workers in the Navanakorn Industrial Zone, Thailand. Thai subjects aged 18 years or older are included in the study.
- Being tested
- Pulmonary function test
- Keywords
- asthma, COPD, pulmonary function, worker, industry, Thailand
- Medical subject headings
- Asthma, Pulmonary Disease, Chronic Obstructive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pulmonary function testDiagnostic test
Spirometry with bronchondilator test will be performed.
| Study group | Role | What they receive |
|---|---|---|
| Workers | Workers aged 18 years or older at Navanakorn industrial zone, Thailand Receives: Diagnostic Test: Pulmonary function test |
What is being measured
The primary outcome is the main question the study is designed to answer.
Prevalence of asthma among workers at the Navanakorn Industrial Zone
Prevalence rate of asthma among workers in the Navanakorn Industrial Zone
Measured: Baseline
Prevalence of COPD among workers in the Navanakorn Industrial Zone
Prevalence rate of COPD among workers in the Navanakorn Industrial Zone
Measured: Baseline
Secondary outcomes (1)
Prevalence of abnormal lung function among workers in the Navanakorn Industrial Zone
Prevalence rate of abnormal lung function among workers in the Navanakorn Industrial Zone
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Feb 2026
- Study start1 Sep 2025
- Primary completion31 Mar 2026
- Study completion31 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (12)Papers the sponsor has linked to this study.
- Other trials for AsthmaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 310 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Thammasat University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Narongkorn Saiphoklang, MD, Thammasat University
- Investigators
- Narongkorn Saiphoklang, MD, Principal investigator, Thammasat University Faculty of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07383896
- Sponsor's protocol ID
- MTU-EC-IM-1-024/68
- Status last verified
- Apr 2026
- First submitted
- 18 Jan 2026
- Last updated
- 17 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: IPD and documents will be available for sharing immediately after publication for a period of 2 years.
Publications
Vested A, Kolstad HA, Basinas I, Burdorf A, Elholm G, Heederik D, Jacobsen GH, Kromhout H, Omland O, Schaumburg I, Sigsgaard T, Vestergaard JM, Wouters IM, Schlunssen V. Dust exposure and the impact on hospital readmission of farming and wood industry workers for asthma and chronic obstructive pulmonary disease (COPD). Scand J Work Environ Health. 2021 Mar 1;47(2):163-168. doi: 10.5271/sjweh.3926. Epub 2020 Oct 19.
PubMed 33073852Garg R, Matreja PS, Maqusood M. Analysis of lung function and respiratory symptoms in brass/metal industrial workers of Moradabad, Uttar Pradesh, India. Ann Afr Med. 2023 Apr-Jun;22(2):219-223. doi: 10.4103/aam.aam_24_22.
PubMed 37026203Bansal N, Lanjewar A, Acharya S, Shukla S. Assessment of pulmonary function test in brick factory workers. J Family Med Prim Care. 2022 Nov;11(11):6916-6919. doi: 10.4103/jfmpc.jfmpc_504_22. Epub 2022 Dec 16.
PubMed 36993005Rafeemanesh E, Alizadeh A, Afshari Saleh L, Zakeri H. A study on respiratory problems and pulmonary function indexes among cement industry workers in Mashhad, Iran. Med Pr. 2015;66(4):471-7. doi: 10.13075/mp.5893.00115.
PubMed 26536964Nasri SM, Putri FA, Sunarno S, Fauzia S, Ramdhan DH. PM2.5 exposure and lung function impairment among fiber-cement industry workers. J Public Health Res. 2023 Jan 13;12(1):22799036221148989. doi: 10.1177/22799036221148989. eCollection 2023 Jan.
PubMed 36654813Elshaer N, Foda N, Shehata S. Respiratory symptoms and pulmonary function impairment among textile industry workers in Alexandria, Egypt. J Public Health Afr. 2023 Oct 1;14(10):2741. doi: 10.4081/jphia.2023.2741. eCollection 2023 Oct 31.
PubMed 38020280Papageorgiou CV, Savourdos P, Douna E, Georgakopoulou VE, Makrodimitri S, Dounias G. Respiratory Symptoms and Pulmonary Function of Workers in the Waste Management Industry. Cureus. 2021 Aug 9;13(8):e17027. doi: 10.7759/cureus.17027. eCollection 2021 Aug.
PubMed 34522508Cox-Ganser JM, White SK, Fedan KB, Bailey RL, Fechter-Leggett E, Cummings KJ. Spirometric Abnormalities and Lung Function Decline in Current and Former Microwave Popcorn and Current Flavoring Manufacturing Workers. J Occup Environ Med. 2020 Jun;62(6):412-419. doi: 10.1097/JOM.0000000000001860.
PubMed 32510907Boonsawat W, Charoenphan P, Kiatboonsri S, Wongtim S, Viriyachaiyo V, Pothirat C, Thanomsieng N. Survey of asthma control in Thailand. Respirology. 2004 Aug;9(3):373-8. doi: 10.1111/j.1440-1843.2004.00584.x.
PubMed 15363011Saiphoklang N, Ruchiwit P, Kanitsap A, Tantiyavarong P, Vatcharavongvan P, Palungrit S, Leelasittikul K, Pugongchai A, Poachanukoon O. Prevalence of Chronic Obstructive Pulmonary Disease and Asthma in the Community of Pathumthani, Thailand. Diseases. 2025 Apr 23;13(5):130. doi: 10.3390/diseases13050130.
PubMed 40422562Saiphoklang N, Ruchiwit P, Kanitsap A, Tantiyavarong P, Vatcharavongvan P, Palungrit S, Leelasittikul K, Pugongchai A, Poachanukoon O. Silicosis and Pulmonary Functions Among Residents Exposed to Dust in Saraburi Thailand. Diseases. 2025 Nov 13;13(11):372. doi: 10.3390/diseases13110372.
PubMed 41294912Saiphoklang N, Ruchiwit P, Vatcharavongvan P, Leelasittikul K, Pugongchai A, Poachanukoon O. Chronic Obstructive Pulmonary Disease and Asthma Among Workers and Residents of Navanakorn Industrial Zone, Thailand. Med Sci (Basel). 2026 Apr 23;14(2):208. doi: 10.3390/medsci14020208.
PubMed 42200999
Study at a glance
From the registry record, last updated by the sponsor on 17 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Chronic Obstructive Pulmonary Disease and Asthma in Workers at Navanakorn Industrial Zone, Thailand
- ClinicalTrials.gov ID
- NCT07383896
- Acronym / sponsor ID
- MTU-EC-IM-1-024/68
- Keywords
- asthma, COPD, pulmonary function, worker, industry, Thailand
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 310 participants (estimated)
- Lead sponsor
- Thammasat UniversityUniversity, hospital or other
- Study start
- 1 Sep 2025 (actual)
- Primary completion
- 31 Mar 2026 (actual)
- Study completion
- 31 May 2026 (estimated)
- First posted
- 3 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to determine the prevalence of asthma and chronic obstructive pulmonary disease (COPD) among workers in an industrial zone in Thailand.
The main question the study aims to answer is:
What is the prevalence of asthma and COPD among workers in Thailand? Participants will complete a questionnaire on respiratory symptoms and undergo pulmonary function testing.
Detailed description
This study is a cross-sectional study. The study aims to determine the prevalence of asthma and COPD among workers in the Navanakorn Industrial Zone, Thailand. Thai subjects aged 18 years or older are included in the study.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Workers | – | Diagnostic Test: Pulmonary function testWorkers aged 18 years or older at Navanakorn industrial zone, Thailand |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Subjects aged 18 years or older who work or live in the Navanakorn Industrial Zone, Thailand.
Key inclusion criteria (1 listed)
- Age 18 years or older
Key exclusion criteria (1 listed)
- Inability to perform spirometry
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pulmonary function testSpirometry with bronchondilator test will be performed. | Diagnostic test | Workers |
Primary outcome
Prevalence of asthma among workers at the Navanakorn Industrial Zone
Time frame: Baseline
Prevalence rate of asthma among workers in the Navanakorn Industrial Zone
Prevalence of COPD among workers in the Navanakorn Industrial Zone
Time frame: Baseline
Prevalence rate of COPD among workers in the Navanakorn Industrial Zone
1 secondary outcome
Prevalence of abnormal lung function among workers in the Navanakorn Industrial Zone
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Apr 2026.
- Results publication: PubMed 33073852Vested A, Kolstad HA, Basinas I, Burdorf A, Elholm G, Heederik D, Jacobsen GH, Kromhout H, Omland O, Schaumburg I, Sigsgaard T, Vestergaard JM, Wouters IM, Schlunssen V. Dust exposure and the impact on hospital readmission of farming and wood industry workers for asthma and chronic obstructive pulmonary disease (COPD). Scand J Work Environ Health. 2021 Mar 1;47(2):163-168. doi: 10.5271/sjweh.3926. Epub 2020 Oct 19.
- Results publication: PubMed 37026203Garg R, Matreja PS, Maqusood M. Analysis of lung function and respiratory symptoms in brass/metal industrial workers of Moradabad, Uttar Pradesh, India. Ann Afr Med. 2023 Apr-Jun;22(2):219-223. doi: 10.4103/aam.aam_24_22.
- Results publication: PubMed 36993005Bansal N, Lanjewar A, Acharya S, Shukla S. Assessment of pulmonary function test in brick factory workers. J Family Med Prim Care. 2022 Nov;11(11):6916-6919. doi: 10.4103/jfmpc.jfmpc_504_22. Epub 2022 Dec 16.
- Results publication: PubMed 26536964Rafeemanesh E, Alizadeh A, Afshari Saleh L, Zakeri H. A study on respiratory problems and pulmonary function indexes among cement industry workers in Mashhad, Iran. Med Pr. 2015;66(4):471-7. doi: 10.13075/mp.5893.00115.
- Results publication: PubMed 36654813Nasri SM, Putri FA, Sunarno S, Fauzia S, Ramdhan DH. PM2.5 exposure and lung function impairment among fiber-cement industry workers. J Public Health Res. 2023 Jan 13;12(1):22799036221148989. doi: 10.1177/22799036221148989. eCollection 2023 Jan.
- Results publication: PubMed 38020280Elshaer N, Foda N, Shehata S. Respiratory symptoms and pulmonary function impairment among textile industry workers in Alexandria, Egypt. J Public Health Afr. 2023 Oct 1;14(10):2741. doi: 10.4081/jphia.2023.2741. eCollection 2023 Oct 31.
- Results publication: PubMed 34522508Papageorgiou CV, Savourdos P, Douna E, Georgakopoulou VE, Makrodimitri S, Dounias G. Respiratory Symptoms and Pulmonary Function of Workers in the Waste Management Industry. Cureus. 2021 Aug 9;13(8):e17027. doi: 10.7759/cureus.17027. eCollection 2021 Aug.
- Results publication: PubMed 32510907Cox-Ganser JM, White SK, Fedan KB, Bailey RL, Fechter-Leggett E, Cummings KJ. Spirometric Abnormalities and Lung Function Decline in Current and Former Microwave Popcorn and Current Flavoring Manufacturing Workers. J Occup Environ Med. 2020 Jun;62(6):412-419. doi: 10.1097/JOM.0000000000001860.
- Results publication: PubMed 15363011Boonsawat W, Charoenphan P, Kiatboonsri S, Wongtim S, Viriyachaiyo V, Pothirat C, Thanomsieng N. Survey of asthma control in Thailand. Respirology. 2004 Aug;9(3):373-8. doi: 10.1111/j.1440-1843.2004.00584.x.
- Results publication: PubMed 40422562Saiphoklang N, Ruchiwit P, Kanitsap A, Tantiyavarong P, Vatcharavongvan P, Palungrit S, Leelasittikul K, Pugongchai A, Poachanukoon O. Prevalence of Chronic Obstructive Pulmonary Disease and Asthma in the Community of Pathumthani, Thailand. Diseases. 2025 Apr 23;13(5):130. doi: 10.3390/diseases13050130.
- Results publication: PubMed 41294912Saiphoklang N, Ruchiwit P, Kanitsap A, Tantiyavarong P, Vatcharavongvan P, Palungrit S, Leelasittikul K, Pugongchai A, Poachanukoon O. Silicosis and Pulmonary Functions Among Residents Exposed to Dust in Saraburi Thailand. Diseases. 2025 Nov 13;13(11):372. doi: 10.3390/diseases13110372.
- Derived from this study: PubMed 42200999Saiphoklang N, Ruchiwit P, Vatcharavongvan P, Leelasittikul K, Pugongchai A, Poachanukoon O. Chronic Obstructive Pulmonary Disease and Asthma Among Workers and Residents of Navanakorn Industrial Zone, Thailand. Med Sci (Basel). 2026 Apr 23;14(2):208. doi: 10.3390/medsci14020208.
- Individual participant dataSharing planned: Yes. IPD and documents will be available for sharing immediately after publication for a period of 2 years.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Narongkorn Saiphoklang, MD principal investigator
Thammasat University Faculty of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Asthma and COPD, run by Thammasat University at 1 site in Thailand.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Thailand. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Narongkorn Saiphoklang, MD (+6629269794, M_narongkorn@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Prevalence of asthma among workers at the Navanakorn Industrial Zone (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07383896, which also lists 12 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Apr 2026.