Adolescence Idiopathic ScoliosisAISNCT07391488
The Effects of Lumbopelvic Rhythm on Postural Control, Daily Activities, and Quality of Life in Individuals With AIS
An observational study of Adolescence Idiopathic Scoliosis, run by Hacettepe University at 1 site in Turkey (Türkiye).
Trial summary
Adolescent idiopathic scoliosis (AIS) leads to three-dimensional spinal deformity during adolescence, causing deviations in the frontal, sagittal, and axial planes, impairing physical function, balance, and lumbopelvic rhythm. Read more about this study
- Who is it for?
- Ages 10 to 18 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Adolescence Idiopathic Scoliosis
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 30 Dec 2025to 8 Oct 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 18 years
- Women only
- Healthy volunteers accepted
- Child, Adult
Study population: The study group will consist of individuals diagnosed with AIS who apply to the Faculty of Physical Therapy and Rehabilitation at Hacettepe University. Participants in the healthy group will be selected using a snowball method from among the relatives of patients who apply to the Faculty of Physical Therapy and Rehabilitation or from among the relatives of the researchers.
Who may be able to join
- Individuals diagnosed with AIS,
- Aged between 10-18 years,
- Having a Cobb angle greater than 10°,
- Having a pain intensity < 3,
- Volunteer individuals.
Who cannot join
- Male gender,
- Body mass index ≥30,
- Presence of additional pathologies affecting the lumbopelvic region (disc herniation, spondylolisthesis, hip dysplasia, rheumatic diseases, etc.),
- Chronic pain lasting longer than 3 months,
- Lower extremity length discrepancy > 2 cm,
- Orthopedic or neurological problems affecting the lower or upper extremity,
Show all 9Show fewer
- History of acute injury,
- History of spinal surgery,
- Individuals with vestibular pathology or severe balance disorders.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Investigation of the Effects of Lumbopelvic Rhythm on Postural Control, Daily Living Activities, and Quality of Life in Adolescent Individuals With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) leads to three-dimensional spinal deformity during adolescence, causing deviations in the frontal, sagittal, and axial planes, impairing physical function, balance, and lumbopelvic rhythm. Individuals with AIS exhibit decreased trunk movement, muscle overactivation, increased energy expenditure, balance/gait disturbances, and abnormalities in proprioceptive/vestibular input; pressure center deviations increase in postural control. These changes negatively impact daily life, pain, and quality of life.
Although the literature has examined the relationships between AIS and muscle activation, range of motion, pelvic position, and gait/balance, the relationship between lumbopelvic rhythm changes and curve type/localization/severity, and its impact on postural control and quality of life, has not been investigated. This study aims to elucidate movement patterns by evaluating lumbopelvic rhythm in individuals with AIS and to guide clinical diagnosis/treatment.
Read the detailed description
Adolescent idiopathic scoliosis (AIS) is a condition that emerges during adolescence and causes a three-dimensional deformity of the spine. This deformity can cause deviations in frontal, sagittal, and axial flight, negatively impacting physical function and balance control mechanisms. Lumbopelvic rhythm ensures the coordination of spinal and pelvic movements and is a critical factor for postural stability. Scoliosis can disrupt lumbopelvic rhythm by affecting pelvic and lumbar region movements. Individuals with AIS have been observed to exhibit changes such as decreased trunk flexion-extension movements and pelvic and hip movements during gait, overactivity of muscles involved in the spine and pelvis, increased energy expenditure, and changes in balance and limb alignment. Abnormalities in vestibular and proprioceptive input have also been observed, leading to changes in balance control. Postural control requires the integration of sensory and motor systems to maintain body balance. In individuals with scoliosis, changes in postural control can reduce mobility. Assessments of postural control, when compared to healthy individuals, have shown that those with scoliosis exhibit higher deviations and acceleration rates in pressure points. This can lead to difficulties in daily living activities, increased pain levels, and decreased quality of life. While the literature examines muscle activation, spinal range of motion, pelvic position, gait, and balance in individuals with AIS, studies on the distribution of lumbopelvic rhythm and its relationship to curvature type, localization, and work, as well as the impact of lumbopelvic rhythm on postural control and quality of life, have not been found. Therefore, evaluating lumbopelvic rhythm in individuals with AIS can contribute to a comprehensive understanding of changes in scoliosis-related movement patterns, guiding clinical diagnosis and treatment.
- Conditions
- Adolescence Idiopathic Scoliosis
- Keywords
- ADOLESCENT IDIOPATHIC SCOLIOSIS, LUMBOPELVIC RHYTHM, POSTURAL CONTROL
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Participants diagnosed with scoliosis who are assessed at a single time point for observational meas | Adolescent idiopathic scoliosis 10-18 age |
What is being measured
The primary outcome is the main question the study is designed to answer.
Lumbopelvic rhythm,
An Inertial Measurement Unit (IMU) will be used to assess lumbopelvic rhythm
Measured: January 30, 2025 - October 8, 2026
Postural control
Postural control will be assessed using the Bertec Balance Check Screener™ strength platform (BP5050 Bertec Co., Columbus, OH, USA) (13).
Measured: January 30, 2025 - October 8, 2026
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Feb 2026
- Study start30 Dec 2025
- Primary completion8 Apr 2026 (estimated)
- Study completion8 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for Adolescence Idiopathic ScoliosisStudies of the same condition, open and under way.
- More trials run by Hacettepe UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hacettepe University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, CEM SAMUT, Hacettepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07391488
- Sponsor's protocol ID
- FTREK25/59
- Acronym
- AIS
- Status last verified
- Jan 2026
- First submitted
- 9 Jan 2026
- Last updated
- 5 Feb 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Piatek E, Kuczynski M, Ostrowska B. Postural control in girls with adolescent idiopathic scoliosis while wearing a Cheneau brace or performing active self-correction: a pilot study. PeerJ. 2019 Aug 29;7:e7513. doi: 10.7717/peerj.7513. eCollection 2019.
PubMed 31528504Pialasse JP, Descarreaux M, Mercier P, Simoneau M. Sensory reweighting is altered in adolescent patients with scoliosis: Evidence from a neuromechanical model. Gait Posture. 2015 Oct;42(4):558-63. doi: 10.1016/j.gaitpost.2015.08.013. Epub 2015 Sep 6.
PubMed 26371828Pialasse JP, Descarreaux M, Mercier P, Blouin J, Simoneau M. The Vestibular-Evoked Postural Response of Adolescents with Idiopathic Scoliosis Is Altered. PLoS One. 2015 Nov 18;10(11):e0143124. doi: 10.1371/journal.pone.0143124. eCollection 2015.
PubMed 26580068Mahaudens P, Thonnard JL, Detrembleur C. Influence of structural pelvic disorders during standing and walking in adolescents with idiopathic scoliosis. Spine J. 2005 Jul-Aug;5(4):427-33. doi: 10.1016/j.spinee.2004.11.014.
PubMed 15996612Mahaudens P, Raison M, Banse X, Mousny M, Detrembleur C. Effect of long-term orthotic treatment on gait biomechanics in adolescent idiopathic scoliosis. Spine J. 2014 Aug 1;14(8):1510-9. doi: 10.1016/j.spinee.2013.08.050. Epub 2013 Oct 4.
PubMed 24314903Abdel-Aziem AA, Abdelraouf OR, Ghally SA, Dahlawi HA, Radwan RE. A 10-Week Program of Combined Hippotherapy and Scroth's Exercises Improves Balance and Postural Asymmetries in Adolescence Idiopathic Scoliosis: A Randomized Controlled Study. Children (Basel). 2021 Dec 30;9(1):23. doi: 10.3390/children9010023.
PubMed 35053648
Study at a glance
From the registry record, last updated by the sponsor on 5 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Effects of Lumbopelvic Rhythm on Postural Control, Daily Living Activities, and Quality of Life in Adolescent Individuals With Idiopathic Scoliosis
- ClinicalTrials.gov ID
- NCT07391488
- Acronym / sponsor ID
- AIS / FTREK25/59
- Conditions
- Adolescence Idiopathic Scoliosis
- Keywords
- ADOLESCENT IDIOPATHIC SCOLIOSIS, LUMBOPELVIC RHYTHM, POSTURAL CONTROL
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Hacettepe UniversityUniversity, hospital or other
- Study start
- 30 Dec 2025 (actual)
- Primary completion
- 8 Apr 2026 (estimated)
- Study completion
- 8 Oct 2026 (estimated)
- First posted
- 5 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Adolescent idiopathic scoliosis (AIS) leads to three-dimensional spinal deformity during adolescence, causing deviations in the frontal, sagittal, and axial planes, impairing physical function, balance, and lumbopelvic rhythm. Individuals with AIS exhibit decreased trunk movement, muscle overactivation, increased energy expenditure, balance/gait disturbances, and abnormalities in proprioceptive/vestibular input; pressure center deviations increase in postural control. These changes negatively impact daily life, pain, and quality of life.
Although the literature has examined the relationships between AIS and muscle activation, range of motion, pelvic position, and gait/balance, the relationship between lumbopelvic rhythm changes and curve type/localization/severity, and its impact on postural control and quality of life, has not been investigated. This study aims to elucidate movement patterns by evaluating lumbopelvic rhythm in individuals with AIS and to guide clinical diagnosis/treatment.
Detailed description
Adolescent idiopathic scoliosis (AIS) is a condition that emerges during adolescence and causes a three-dimensional deformity of the spine. This deformity can cause deviations in frontal, sagittal, and axial flight, negatively impacting physical function and balance control mechanisms. Lumbopelvic rhythm ensures the coordination of spinal and pelvic movements and is a critical factor for postural stability. Scoliosis can disrupt lumbopelvic rhythm by affecting pelvic and lumbar region movements. Individuals with AIS have been observed to exhibit changes such as decreased trunk flexion-extension movements and pelvic and hip movements during gait, overactivity of muscles involved in the spine and pelvis, increased energy expenditure, and changes in balance and limb alignment. Abnormalities in vestibular and proprioceptive input have also been observed, leading to changes in balance control. Postural control requires the integration of sensory and motor systems to maintain body balance. In individuals with scoliosis, changes in postural control can reduce mobility. Assessments of postural control, when compared to healthy individuals, have shown that those with scoliosis exhibit higher deviations and acceleration rates in pressure points. This can lead to difficulties in daily living activities, increased pain levels, and decreased quality of life. While the literature examines muscle activation, spinal range of motion, pelvic position, gait, and balance in individuals with AIS, studies on the distribution of lumbopelvic rhythm and its relationship to curvature type, localization, and work, as well as the impact of lumbopelvic rhythm on postural control and quality of life, have not been found. Therefore, evaluating lumbopelvic rhythm in individuals with AIS can contribute to a comprehensive understanding of changes in scoliosis-related movement patterns, guiding clinical diagnosis and treatment.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Participants diagnosed with scoliosis who are assessed at a single time point for observational meas | – | –Adolescent idiopathic scoliosis 10-18 age |
Who may qualify
- Ages
- 10 to 18 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- The study group will consist of individuals diagnosed with AIS who apply to the Faculty of Physical Therapy and Rehabilitation at Hacettepe University. Participants in the healthy group will be selected using a snowball method from among the relatives of patients who apply to the Faculty of Physical Therapy and Rehabilitation or from among the relatives of the researchers.
Key inclusion criteria (5 listed)
- Individuals diagnosed with AIS,
- Aged between 10-18 years,
- Having a Cobb angle greater than 10°,
- Having a pain intensity < 3,
- Volunteer individuals.
Key exclusion criteria (9 listed)
- Male gender,
- Body mass index ≥30,
- Presence of additional pathologies affecting the lumbopelvic region (disc herniation, spondylolisthesis, hip dysplasia, rheumatic diseases, etc.),
- Chronic pain lasting longer than 3 months,
- Lower extremity length discrepancy > 2 cm,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Lumbopelvic rhythm,
Time frame: January 30, 2025 - October 8, 2026
An Inertial Measurement Unit (IMU) will be used to assess lumbopelvic rhythm
Postural control
Time frame: January 30, 2025 - October 8, 2026
Postural control will be assessed using the Bertec Balance Check Screener™ strength platform (BP5050 Bertec Co., Columbus, OH, USA) (13).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Feb 2026.
- Background: PubMed 31528504Piatek E, Kuczynski M, Ostrowska B. Postural control in girls with adolescent idiopathic scoliosis while wearing a Cheneau brace or performing active self-correction: a pilot study. PeerJ. 2019 Aug 29;7:e7513. doi: 10.7717/peerj.7513. eCollection 2019.
- Background: PubMed 26371828Pialasse JP, Descarreaux M, Mercier P, Simoneau M. Sensory reweighting is altered in adolescent patients with scoliosis: Evidence from a neuromechanical model. Gait Posture. 2015 Oct;42(4):558-63. doi: 10.1016/j.gaitpost.2015.08.013. Epub 2015 Sep 6.
- Background: PubMed 26580068Pialasse JP, Descarreaux M, Mercier P, Blouin J, Simoneau M. The Vestibular-Evoked Postural Response of Adolescents with Idiopathic Scoliosis Is Altered. PLoS One. 2015 Nov 18;10(11):e0143124. doi: 10.1371/journal.pone.0143124. eCollection 2015.
- Background: PubMed 15996612Mahaudens P, Thonnard JL, Detrembleur C. Influence of structural pelvic disorders during standing and walking in adolescents with idiopathic scoliosis. Spine J. 2005 Jul-Aug;5(4):427-33. doi: 10.1016/j.spinee.2004.11.014.
- Background: PubMed 24314903Mahaudens P, Raison M, Banse X, Mousny M, Detrembleur C. Effect of long-term orthotic treatment on gait biomechanics in adolescent idiopathic scoliosis. Spine J. 2014 Aug 1;14(8):1510-9. doi: 10.1016/j.spinee.2013.08.050. Epub 2013 Oct 4.
- Background: PubMed 35053648Abdel-Aziem AA, Abdelraouf OR, Ghally SA, Dahlawi HA, Radwan RE. A 10-Week Program of Combined Hippotherapy and Scroth's Exercises Improves Balance and Postural Asymmetries in Adolescence Idiopathic Scoliosis: A Randomized Controlled Study. Children (Basel). 2021 Dec 30;9(1):23. doi: 10.3390/children9010023.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Adolescence Idiopathic Scoliosis, run by Hacettepe University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 5 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Lumbopelvic rhythm, (time frame: January 30, 2025 - October 8, 2026). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07391488, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Feb 2026.