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Music Therapy for Pain and SedationNCT07391891

Musical Mindfulness for Pain in the ED Waiting Room

A study testing Music intervention in people with Music Therapy for Pain and Sedation and Neck Pain Musculoskeletal, run by University of California, Irvine at 1 site in United States.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts
Official record
Search all trials

Trial summary

Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. Read more about this study

Who is it for?
Ages 18 to 75 years
What is being tested?
Music intervention
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
1 siteUnited States
Study dates
15 Feb 2026to 30 Apr 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 75 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • - Age >= 18 years old and <=75 years old
  • Patient presents with neck or back pain

Who cannot join

None listed.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Sean Young, PhD contact

6502455490

syoung5@hs.uci.edu

Danielle Matonis, MD contact

dmatonis@hs.uci.edu

United States1 site
  • University of California, Irvine, Emergency Department

    Orange, California, 92868

    Phone Number of ED, 714-456-8008

Other trials in United States

About this study

Official title: Use of Music Mindfulness for Pain Management in the ED Waiting Room

Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. However, with the current ongoing opioid epidemic, it is important to consider other methods, both pharmacologic and nonpharmacologic, of pain reduction. Jazz music specifically has been demonstrated to have therapeutic effects on pain that can be used to lower the quantity of opioids administered to patients.

Non-pharmacological interventions in the emergency department for pain typically consist of splinting an injury, applying heat or cold, or various distractions following initial and sequential pain assessment. Pharmacological interventions for pain in the Emergency Department involve the administration of acetaminophen, muscle relaxers, topical anesthetics, opioids, to name a few.

Read more

In the emergency department (ED), providers are increasingly hesitant to prescribe opioids over the past decade due to the current opioid epidemic, in which there is an increasing proportion of people that develop an addiction to opioids, including those that are prescribed to them for pain management.. While emergency medicine providers' decrease in opioid prescriptions pertains to their implementation of opioid-prescribing policies, little evidence has been found demonstrating a direct link in these policies to decreases in substance misuse. Consequently, providers find themselves needing to become ingenious in their approach to pain in patients through the integration of pharmacologic and non-pharmacologic mediums of analgesia.

A recent randomized controlled trial (RCT) from Brigham and Women's Hospital in Boston sought to identify the qualitative responses from patients in the ED following the arbitrary distribution of either supervised or unsupervised music therapy over a time period of 4 hours. The initial results found that, generally speaking, music therapy may lower reported pain and anxiety scores. Furthermore, stronger results were identified in case subjects with higher initial reports of pain via a pain catastrophizing scale, implying that a higher baseline of pain results in more relief from music therapy. One shortcoming in the article is the lack of analysis with reported results and the biopsychosocial model of pain. Heavy emphasis is placed on the psychological and social components of pain in the Brigham and Women's article through the implementation of the Pain Catastrophizing Scale and Brief Pain Inventory scoring done during the RCT, but no focus on linked biological changes in the subjects through the music therapy intervention.

The purpose of this study is to (i.) assess the effect of a video training about musical pain management followed by a 15-minute music listening intervention on self-reported pain scores in ED patients with neck and back pain. The investigators also aim to (ii.) evaluate patient satisfaction and emotional response following the intervention. Opioid medications are commonly used to reduce substantial pain, and music therapy has been found to reduce associated pain and anxiety in patients, then the use of music therapy could be an aid in medicine to reduce opioid intake. The investigators hypothesize that the usage of a training on musical pain management combined with a specified jazz musical intervention will produce a significantly lower measured pain score in comparison to a video on mindful pain management followed by the patient's choice of activities.

Read the detailed description
  1. Patients presenting to the Emergency Department with neck or back pain in the waiting room are approached for the study.
  2. Researchers confirm patients' interest. Consent patient by having them sign the HIPAA Waiver and Informed Consent Form.
  3. Obtain an initial pain measurement of the subject prior to randomization. Additionally, obtain demographic information about the subject
  4. Randomize subjects into either the intervention group (mindful music listening video followed by jazz music playlist administration) or the control group (pain management video followed by video or music of participants choice administered) using a simple randomizer, such as the Sealed Envelope application.
  5. Deliver musical pain management video (intervention group) OR allow for the current standard of care with pain management presentation video for 15 minutes (control group).
  6. Deliver musical intervention to subjects in the intervention group for 15 minutes, or allow subjects in the control group to listen to music or video of their choice for 15 minutes.
  7. Following the 15-minute music intervention or 15-minute control, obtain a new pain measurement
  8. Follow up after 30 minutes after the music intervention finished and acquire pain measurements again
  9. Follow up 1 hour after the music intervention finished and acquire pain measurements again
  10. Administer brief survey to patient asking if they enjoyed or disliked the experience of the study and if they are likely or unlikely to participate again.
Being tested
Music intervention
Keywords
Music therapy, Music pain management, Musical pain managament, Opioid epidemic, Therapeutic medicine, Emergency Medicine, Emergency Room, Waiting Room, Music intervention, Jazz music, back pain, neck pain, musculoskeletal, musculoskeletal pain, pain, pain management, music
Medical subject headings
Back Pain, Emergencies, Neck Pain, Musculoskeletal Pain, Pain, Agnosia

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Music interventionBehavioural

    Participant's will be taught how to mindfully listen to jazz to reduce pain

Study groups in NCT07391891
Study groupRoleWhat they receive
Mindful Music Training + Music InterventionExperimentalParticipants will be given a video training on listening to music mindfully to reduce pain. Following this, patients will be given a 15-minute jazz music playlist to listen to.
Receives: Behavioral: Music intervention
Standard of Care Pain Management Training + Participant's Choice of InterventionActive comparatorParticipants will be given a video demonstrating how to mindfully manage pain, following this will be a 15-minute period of the participant's choice of activity
Receives: Behavioral: Music intervention

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Pain score using Pain, Enjoyment of Life and General Activity Scale (PEG)

    Pain score will be obtained using PEG scale

    Title of first scale: Pain Pain will be rated on a scale of 0-10 , with 0 being no pain, and 10 being pain as bad as you can imagine (pain increases as scale increases)

    Title of second scale: Interference Interference will be rated on a scale of 0-10, with 0 being no interference, and 10 being completely interferes (interference increases as scale increases) Higher score is a worse outcome

    Measured: Day 1

  2. Pain Intensity

    Pain will be scored using pain intensity scale Title of scale: Frequency 0-3, with 0 being not at all and 3 being nearly every day Higher score is a worse outcome

    Measured: Day 1

Secondary outcomes (1)
  1. Satisfaction with Study

    Participants will be asked their satisfaction of the study to gauge if music therapy or mindful pain management is a feasible process in the Emergency Department Waiting Room

    How positive was your experience from 1-5, which 1 being horrible and 5 being amazing?

    How likely would you be to recommend this study to others undergoing similar pain, with 1 being not likely at all and 5 being extremely likely ?

    How easy was it to participate in this study from 1-5, with 1 being not easy at all, and 5 being extremely easy ?

    Would you consider undergoing this procedure again in the future? Yes or no, and why?

    Measured: 1 hour and 30 minutes after baseline

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 Feb 2026
  2. Study start15 Feb 2026 (estimated)
  3. Primary completion30 Apr 2026 (estimated)
  4. Study completion30 Apr 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
60 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07391891
Sponsor's protocol ID
STUDY00000311
Status last verified
Jan 2026
First submitted
18 Nov 2025
Last updated
6 Feb 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Pourmand A, Jasani G, Shay C, Mazer-Amirshahi M. The Evolving Landscape of Acute Pain Management in the Era of the Opioid Crisis. Curr Pain Headache Rep. 2018 Aug 27;22(11):73. doi: 10.1007/s11916-018-0728-y.

    PubMed 30151792
  • Young SD, Kim J, Hanley A. Mindful Jazz and Preferred Music Interventions Reduce Pain Among Patients With Chronic Pain and Anxiety: A Pilot Randomized Controlled Trial. Cureus. 2025 Mar 12;17(3):e80485. doi: 10.7759/cureus.80485. eCollection 2025 Mar.

    PubMed 40225443
  • Chanana L, Jegaraj MA, Kalyaniwala K, Yadav B, Abilash K. Clinical profile of non-traumatic acute abdominal pain presenting to an adult emergency department. J Family Med Prim Care. 2015 Jul-Sep;4(3):422-5. doi: 10.4103/2249-4863.161344.

    PubMed 26288785
  • Chai PR, Schwartz E, Hasdianda MA, Azizoddin DR, Kikut A, Jambaulikar GD, Edwards RR, Boyer EW, Schreiber KL. A Brief Music App to Address Pain in the Emergency Department: Prospective Study. J Med Internet Res. 2020 May 20;22(5):e18537. doi: 10.2196/18537.

    PubMed 32432550

Questions about this trial

What is this clinical trial studying?

A study testing Music intervention in people with Music Therapy for Pain and Sedation and Neck Pain Musculoskeletal, run by University of California, Irvine at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 6 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Sean Young, PhD (6502455490, syoung5@hs.uci.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Pain score using Pain, Enjoyment of Life and General Activity Scale (PEG) (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07391891, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2026.

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