Music Therapy for Pain and SedationNCT07391891
Musical Mindfulness for Pain in the ED Waiting Room
A study testing Music intervention in people with Music Therapy for Pain and Sedation and Neck Pain Musculoskeletal, run by University of California, Irvine at 1 site in United States.
Trial summary
Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
- What is being tested?
- Music intervention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Feb 2026to 30 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- - Age >= 18 years old and <=75 years old
- Patient presents with neck or back pain
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Danielle Matonis, MD contact
United States1 site
University of California, Irvine, Emergency Department
Orange, California, 92868
Phone Number of ED, 714-456-8008
About this study
Official title: Use of Music Mindfulness for Pain Management in the ED Waiting Room
Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. However, with the current ongoing opioid epidemic, it is important to consider other methods, both pharmacologic and nonpharmacologic, of pain reduction. Jazz music specifically has been demonstrated to have therapeutic effects on pain that can be used to lower the quantity of opioids administered to patients.
Non-pharmacological interventions in the emergency department for pain typically consist of splinting an injury, applying heat or cold, or various distractions following initial and sequential pain assessment. Pharmacological interventions for pain in the Emergency Department involve the administration of acetaminophen, muscle relaxers, topical anesthetics, opioids, to name a few.
Read more
In the emergency department (ED), providers are increasingly hesitant to prescribe opioids over the past decade due to the current opioid epidemic, in which there is an increasing proportion of people that develop an addiction to opioids, including those that are prescribed to them for pain management.. While emergency medicine providers' decrease in opioid prescriptions pertains to their implementation of opioid-prescribing policies, little evidence has been found demonstrating a direct link in these policies to decreases in substance misuse. Consequently, providers find themselves needing to become ingenious in their approach to pain in patients through the integration of pharmacologic and non-pharmacologic mediums of analgesia.
A recent randomized controlled trial (RCT) from Brigham and Women's Hospital in Boston sought to identify the qualitative responses from patients in the ED following the arbitrary distribution of either supervised or unsupervised music therapy over a time period of 4 hours. The initial results found that, generally speaking, music therapy may lower reported pain and anxiety scores. Furthermore, stronger results were identified in case subjects with higher initial reports of pain via a pain catastrophizing scale, implying that a higher baseline of pain results in more relief from music therapy. One shortcoming in the article is the lack of analysis with reported results and the biopsychosocial model of pain. Heavy emphasis is placed on the psychological and social components of pain in the Brigham and Women's article through the implementation of the Pain Catastrophizing Scale and Brief Pain Inventory scoring done during the RCT, but no focus on linked biological changes in the subjects through the music therapy intervention.
The purpose of this study is to (i.) assess the effect of a video training about musical pain management followed by a 15-minute music listening intervention on self-reported pain scores in ED patients with neck and back pain. The investigators also aim to (ii.) evaluate patient satisfaction and emotional response following the intervention. Opioid medications are commonly used to reduce substantial pain, and music therapy has been found to reduce associated pain and anxiety in patients, then the use of music therapy could be an aid in medicine to reduce opioid intake. The investigators hypothesize that the usage of a training on musical pain management combined with a specified jazz musical intervention will produce a significantly lower measured pain score in comparison to a video on mindful pain management followed by the patient's choice of activities.
Read the detailed description
- Patients presenting to the Emergency Department with neck or back pain in the waiting room are approached for the study.
- Researchers confirm patients' interest. Consent patient by having them sign the HIPAA Waiver and Informed Consent Form.
- Obtain an initial pain measurement of the subject prior to randomization. Additionally, obtain demographic information about the subject
- Randomize subjects into either the intervention group (mindful music listening video followed by jazz music playlist administration) or the control group (pain management video followed by video or music of participants choice administered) using a simple randomizer, such as the Sealed Envelope application.
- Deliver musical pain management video (intervention group) OR allow for the current standard of care with pain management presentation video for 15 minutes (control group).
- Deliver musical intervention to subjects in the intervention group for 15 minutes, or allow subjects in the control group to listen to music or video of their choice for 15 minutes.
- Following the 15-minute music intervention or 15-minute control, obtain a new pain measurement
- Follow up after 30 minutes after the music intervention finished and acquire pain measurements again
- Follow up 1 hour after the music intervention finished and acquire pain measurements again
- Administer brief survey to patient asking if they enjoyed or disliked the experience of the study and if they are likely or unlikely to participate again.
- Being tested
- Music intervention
- Keywords
- Music therapy, Music pain management, Musical pain managament, Opioid epidemic, Therapeutic medicine, Emergency Medicine, Emergency Room, Waiting Room, Music intervention, Jazz music, back pain, neck pain, musculoskeletal, musculoskeletal pain, pain, pain management, music
- Medical subject headings
- Back Pain, Emergencies, Neck Pain, Musculoskeletal Pain, Pain, Agnosia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Music interventionBehavioural
Participant's will be taught how to mindfully listen to jazz to reduce pain
| Study group | Role | What they receive |
|---|---|---|
| Mindful Music Training + Music Intervention | Experimental | Participants will be given a video training on listening to music mindfully to reduce pain. Following this, patients will be given a 15-minute jazz music playlist to listen to. Receives: Behavioral: Music intervention |
| Standard of Care Pain Management Training + Participant's Choice of Intervention | Active comparator | Participants will be given a video demonstrating how to mindfully manage pain, following this will be a 15-minute period of the participant's choice of activity Receives: Behavioral: Music intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain score using Pain, Enjoyment of Life and General Activity Scale (PEG)
Pain score will be obtained using PEG scale
Title of first scale: Pain Pain will be rated on a scale of 0-10 , with 0 being no pain, and 10 being pain as bad as you can imagine (pain increases as scale increases)
Title of second scale: Interference Interference will be rated on a scale of 0-10, with 0 being no interference, and 10 being completely interferes (interference increases as scale increases) Higher score is a worse outcome
Measured: Day 1
Pain Intensity
Pain will be scored using pain intensity scale Title of scale: Frequency 0-3, with 0 being not at all and 3 being nearly every day Higher score is a worse outcome
Measured: Day 1
Secondary outcomes (1)
Satisfaction with Study
Participants will be asked their satisfaction of the study to gauge if music therapy or mindful pain management is a feasible process in the Emergency Department Waiting Room
How positive was your experience from 1-5, which 1 being horrible and 5 being amazing?
How likely would you be to recommend this study to others undergoing similar pain, with 1 being not likely at all and 5 being extremely likely ?
How easy was it to participate in this study from 1-5, with 1 being not easy at all, and 5 being extremely easy ?
Would you consider undergoing this procedure again in the future? Yes or no, and why?
Measured: 1 hour and 30 minutes after baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Feb 2026
- Study start15 Feb 2026 (estimated)
- Primary completion30 Apr 2026 (estimated)
- Study completion30 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Music Therapy for Pain and SedationStudies of the same condition, open and under way.
- More trials run by University of California, IrvineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of California, Irvine
- Sponsor type
- University, hospital or other
- Collaborators
- National Center for Complementary and Integrative Health (NCCIH)
- Responsible party
- Principal investigator, Sean D Young, University of California, Irvine
- Investigators
- Sean Young, PhD, Principal investigator, University of California, Irvine. Department of Emergency MedicineRyan Rokerya, Expected BS Dec 2026, Study chair, University of California, Irvine. Department of Emergency MedicineTyler Mitchell, Expected BS Jun 2026, Study chair, University of California, Irvine. Department of Emergency MedicineDominic A Ugarte, M.D., Study chair, University of California, Irvine. Department of Emergency Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07391891
- Sponsor's protocol ID
- STUDY00000311
- Status last verified
- Jan 2026
- First submitted
- 18 Nov 2025
- Last updated
- 6 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Pourmand A, Jasani G, Shay C, Mazer-Amirshahi M. The Evolving Landscape of Acute Pain Management in the Era of the Opioid Crisis. Curr Pain Headache Rep. 2018 Aug 27;22(11):73. doi: 10.1007/s11916-018-0728-y.
PubMed 30151792Young SD, Kim J, Hanley A. Mindful Jazz and Preferred Music Interventions Reduce Pain Among Patients With Chronic Pain and Anxiety: A Pilot Randomized Controlled Trial. Cureus. 2025 Mar 12;17(3):e80485. doi: 10.7759/cureus.80485. eCollection 2025 Mar.
PubMed 40225443Chanana L, Jegaraj MA, Kalyaniwala K, Yadav B, Abilash K. Clinical profile of non-traumatic acute abdominal pain presenting to an adult emergency department. J Family Med Prim Care. 2015 Jul-Sep;4(3):422-5. doi: 10.4103/2249-4863.161344.
PubMed 26288785Chai PR, Schwartz E, Hasdianda MA, Azizoddin DR, Kikut A, Jambaulikar GD, Edwards RR, Boyer EW, Schreiber KL. A Brief Music App to Address Pain in the Emergency Department: Prospective Study. J Med Internet Res. 2020 May 20;22(5):e18537. doi: 10.2196/18537.
PubMed 32432550
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Use of Music Mindfulness for Pain Management in the ED Waiting Room
- ClinicalTrials.gov ID
- NCT07391891
- Acronym / sponsor ID
- STUDY00000311
- Keywords
- Music therapy, Music pain management, Musical pain managament, Opioid epidemic, Therapeutic medicine, Emergency Medicine, Emergency Room, Waiting Room
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- University of California, IrvineUniversity, hospital or other
- Collaborators
- National Center for Complementary and Integrative Health (NCCIH)
- Study start
- 15 Feb 2026 (estimated)
- Primary completion
- 30 Apr 2026 (estimated)
- Study completion
- 30 Apr 2026 (estimated)
- First posted
- 6 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. However, with the current ongoing opioid epidemic, it is important to consider other methods, both pharmacologic and nonpharmacologic, of pain reduction. Jazz music specifically has been demonstrated to have therapeutic effects on pain that can be used to lower the quantity of opioids administered to patients.
Non-pharmacological interventions in the emergency department for pain typically consist of splinting an injury, applying heat or cold, or various distractions following initial and sequential pain assessment. Pharmacological interventions for pain in the Emergency Department involve the administration of acetaminophen, muscle relaxers, topical anesthetics, opioids, to name a few.
In the emergency department (ED), providers are increasingly hesitant to prescribe opioids over the past decade due to the current opioid epidemic, in which there is an increasing proportion of people that develop an addiction to opioids, including those that are prescribed to them for pain management.. While emergency medicine providers' decrease in opioid prescriptions pertains to their implementation of opioid-prescribing policies, little evidence has been found demonstrating a direct link in these policies to decreases in substance misuse. Consequently, providers find themselves needing to become ingenious in their approach to pain in patients through the integration of pharmacologic and non-pharmacologic mediums of analgesia.
A recent randomized controlled trial (RCT) from Brigham and Women's Hospital in Boston sought to identify the qualitative responses from patients in the ED following the arbitrary distribution of either supervised or unsupervised music therapy over a time period of 4 hours. The initial results found that, generally speaking, music therapy may lower reported pain and anxiety scores. Furthermore, stronger results were identified in case subjects with higher initial reports of pain via a pain catastrophizing scale, implying that a higher baseline of pain results in more relief from music therapy. One shortcoming in the article is the lack of analysis with reported results and the biopsychosocial model of pain. Heavy emphasis is placed on the psychological and social components of pain in the Brigham and Women's article through the implementation of the Pain Catastrophizing Scale and Brief Pain Inventory scoring done during the RCT, but no focus on linked biological changes in the subjects through the music therapy intervention.
The purpose of this study is to (i.) assess the effect of a video training about musical pain management followed by a 15-minute music listening intervention on self-reported pain scores in ED patients with neck and back pain. The investigators also aim to (ii.) evaluate patient satisfaction and emotional response following the intervention. Opioid medications are commonly used to reduce substantial pain, and music therapy has been found to reduce associated pain and anxiety in patients, then the use of music therapy could be an aid in medicine to reduce opioid intake. The investigators hypothesize that the usage of a training on musical pain management combined with a specified jazz musical intervention will produce a significantly lower measured pain score in comparison to a video on mindful pain management followed by the patient's choice of activities.
Detailed description
- Patients presenting to the Emergency Department with neck or back pain in the waiting room are approached for the study.
- Researchers confirm patients' interest. Consent patient by having them sign the HIPAA Waiver and Informed Consent Form.
- Obtain an initial pain measurement of the subject prior to randomization. Additionally, obtain demographic information about the subject
- Randomize subjects into either the intervention group (mindful music listening video followed by jazz music playlist administration) or the control group (pain management video followed by video or music of participants choice administered) using a simple randomizer, such as the Sealed Envelope application.
- Deliver musical pain management video (intervention group) OR allow for the current standard of care with pain management presentation video for 15 minutes (control group).
- Deliver musical intervention to subjects in the intervention group for 15 minutes, or allow subjects in the control group to listen to music or video of their choice for 15 minutes.
- Following the 15-minute music intervention or 15-minute control, obtain a new pain measurement
- Follow up after 30 minutes after the music intervention finished and acquire pain measurements again
- Follow up 1 hour after the music intervention finished and acquire pain measurements again
- Administer brief survey to patient asking if they enjoyed or disliked the experience of the study and if they are likely or unlikely to participate again.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Mindful Music Training + Music Intervention | Experimental | Behavioral: Music interventionParticipants will be given a video training on listening to music mindfully to reduce pain. Following this, patients will be given a 15-minute jazz music playlist to listen to. |
| Standard of Care Pain Management Training + Participant's Choice of Intervention | Active comparator | Behavioral: Music interventionParticipants will be given a video demonstrating how to mindfully manage pain, following this will be a 15-minute period of the participant's choice of activity |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- - Age >= 18 years old and <=75 years old
- Patient presents with neck or back pain
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Music interventionParticipant's will be taught how to mindfully listen to jazz to reduce pain | Behavioural | Mindful Music Training + Music Intervention, Standard of Care Pain Management Training + Participant's Choice of Intervention |
Primary outcome
Pain score using Pain, Enjoyment of Life and General Activity Scale (PEG)
Time frame: Day 1
Pain score will be obtained using PEG scale Title of first scale: Pain Pain will be rated on a scale of 0-10 , with 0 being no pain, and 10 being pain as bad as you can imagine (pain increases as scale increases) Title of second scale: Interference Interference will be rated on a scale of 0-10, with 0 being no interference, and 10 being completely interferes (interference increases as scale increases) Higher score is a worse outcome
Pain Intensity
Time frame: Day 1
Pain will be scored using pain intensity scale Title of scale: Frequency 0-3, with 0 being not at all and 3 being nearly every day Higher score is a worse outcome
1 secondary outcome
Satisfaction with Study
Time frame: 1 hour and 30 minutes after baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2026.
- Background: PubMed 30151792Pourmand A, Jasani G, Shay C, Mazer-Amirshahi M. The Evolving Landscape of Acute Pain Management in the Era of the Opioid Crisis. Curr Pain Headache Rep. 2018 Aug 27;22(11):73. doi: 10.1007/s11916-018-0728-y.
- Background: PubMed 40225443Young SD, Kim J, Hanley A. Mindful Jazz and Preferred Music Interventions Reduce Pain Among Patients With Chronic Pain and Anxiety: A Pilot Randomized Controlled Trial. Cureus. 2025 Mar 12;17(3):e80485. doi: 10.7759/cureus.80485. eCollection 2025 Mar.
- Background: PubMed 26288785Chanana L, Jegaraj MA, Kalyaniwala K, Yadav B, Abilash K. Clinical profile of non-traumatic acute abdominal pain presenting to an adult emergency department. J Family Med Prim Care. 2015 Jul-Sep;4(3):422-5. doi: 10.4103/2249-4863.161344.
- Background: PubMed 32432550Chai PR, Schwartz E, Hasdianda MA, Azizoddin DR, Kikut A, Jambaulikar GD, Edwards RR, Boyer EW, Schreiber KL. A Brief Music App to Address Pain in the Emergency Department: Prospective Study. J Med Internet Res. 2020 May 20;22(5):e18537. doi: 10.2196/18537.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Danielle Matonis, MD contact
Sean Young, PhD principal investigator
University of California, Irvine. Department of Emergency Medicine
Ryan Rokerya, Expected BS Dec 2026 study chair
University of California, Irvine. Department of Emergency Medicine
Tyler Mitchell, Expected BS Jun 2026 study chair
University of California, Irvine. Department of Emergency Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Music intervention in people with Music Therapy for Pain and Sedation and Neck Pain Musculoskeletal, run by University of California, Irvine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 6 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sean Young, PhD (6502455490, syoung5@hs.uci.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain score using Pain, Enjoyment of Life and General Activity Scale (PEG) (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07391891, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2026.