MND (Motor Neurone DIsease)NCT07393932
MND Together: Phase 1
An observational study of MND (Motor Neurone DIsease), run by University of Sheffield at 1 site in United Kingdom.
Trial summary
This project consists of two workstreams, both of which will be mixed-methods and aim to develop a national UK picture of current care coordination for people with MND, including observations of barriers and facilitators. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- MND (Motor Neurone DIsease)
- What is being tested?
- Not applicable- observational study
- How many people
- 287 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- Feb 2026to Feb 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: People attending MND specialist centres and non specialist community services
Who may be able to join
- Person with MND, carers, former carers, Health and Social Care Professionals, managers and commissioners
- Ability to engage in focus group or interview or email interview
- Person with MND, carers, former carers, Health and Social Care Professionals, managers and commissioners
- Ability to engage in an observations and interviews
Who cannot join
- no exclusion criteria
- WS2
- no exclusion criteria
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site
School of Medicine and Populational Health
Sheffield, Yorkshire
Liam Knox, PhD, +44 1142222291, l.knox@sheffield.ac.uk
Chris McDermott, MBChB, FRCP, PhD, +44 114 222 2295, c.j.mcdermott@sheffield.ac.uk
About this study
Official title: MND Together: Improving Communication and Coordination of Motor Neuron Disease Care
This project consists of two workstreams, both of which will be mixed-methods and aim to develop a national UK picture of current care coordination for people with MND, including observations of barriers and facilitators. The studies will explore how care is transferred and communicated across MND specialist services to non-specialist community health settings.
In workstream 1, the researchers will conduct focus groups with people with MND, Carers, former Carers, Health and Social Care Professionals and managers and commissioners. These focus groups, alongside the analysis of routine data, will create a national picture of MND care and begin a behavioural diagnosis of the barriers and facilitators. In workstream 2, a multi-site ethnography study will be conducted, including observations, interviews, routine data, care plan and document review. This Workstream will observe how care is coordinated between specialist and non-specialist services and continue to explore barriers and facilitators that can not be identified through interviews.
- Conditions
- MND (Motor Neurone DIsease)
- Being tested
- Not applicable- observational study
- Keywords
- MND, Care coordination, health and social care, multidisciplinary care, community services, Motor Neurone Disease, Neurological conditions, ethnography, Amyotrophic lateral sclerosis (ALS), Qualitative
- Medical subject headings
- Amyotrophic Lateral Sclerosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Not applicable- observational studyOther
MND-Together tool will be informed by the findings from this study
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of barriers and facilitators for capability, opportunity and motivation (COM-B)
Measured: February 2026- February 2027
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Feb 2026
- Study startFeb 2026 (estimated)
- Primary completionDec 2026 (estimated)
- Study completionFeb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for MND (Motor Neurone DIsease)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Other
- Enrolment
- 287 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Sheffield
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute for Health Research, United Kingdom, Liverpool John Moores University, Sheffield Teaching Hospitals NHS Foundation Trust, Cornwall Partnership NHS Foundation Trust, Northern Lincolnshire and Goole Hospitals NHS Foundation Trust, Dementias Platform UK, NIHR HealthTech Research Centre, Swansea Bay University Health Board
- Responsible party
- Sponsor
- Investigators
- Liam Knox, PhD, Principal investigator, University of SheffieldChris McDermott, MBChB, FRCP, PhD, Principal investigator, University of Sheffield
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07393932
- Sponsor's protocol ID
- R/186866
- Status last verified
- Jan 2026
- First submitted
- 15 Jan 2026
- Last updated
- 6 Feb 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The pseudo-anonymised data, and analysis output will be uploaded to the University of Sheffield data repository, ORDA, and stored for 10 years as per the University of Sheffield Retention Schedule. The data will be embargoed until the study has been published in a peer-reviewed journal and will be available thereafter to other researchers upon reasonable request to the CI.
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- MND Together: Improving Communication and Coordination of Motor Neuron Disease Care
- ClinicalTrials.gov ID
- NCT07393932
- Acronym / sponsor ID
- R/186866
- Conditions
- MND (Motor Neurone DIsease)
- Keywords
- MND, Care coordination, health and social care, multidisciplinary care, community services, Motor Neurone Disease, Neurological conditions, ethnography
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 287 participants (estimated)
- Lead sponsor
- University of SheffieldUniversity, hospital or other
- Collaborators
- National Institute for Health Research, United Kingdom, Liverpool John Moores University, Sheffield Teaching Hospitals NHS Foundation Trust, Cornwall Partnership NHS Foundation Trust, Northern Lincolnshire and Goole Hospitals NHS Foundation Trust, Dementias Platform UK, NIHR HealthTech Research Centre, Swansea Bay University Health Board
- Study start
- Feb 2026 (estimated)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Feb 2027 (estimated)
- First posted
- 6 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project consists of two workstreams, both of which will be mixed-methods and aim to develop a national UK picture of current care coordination for people with MND, including observations of barriers and facilitators. The studies will explore how care is transferred and communicated across MND specialist services to non-specialist community health settings.
In workstream 1, the researchers will conduct focus groups with people with MND, Carers, former Carers, Health and Social Care Professionals and managers and commissioners. These focus groups, alongside the analysis of routine data, will create a national picture of MND care and begin a behavioural diagnosis of the barriers and facilitators. In workstream 2, a multi-site ethnography study will be conducted, including observations, interviews, routine data, care plan and document review. This Workstream will observe how care is coordinated between specialist and non-specialist services and continue to explore barriers and facilitators that can not be identified through interviews.
Study design
- Observational model
- Case only
- Time perspective
- Other
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- People attending MND specialist centres and non specialist community services
Key inclusion criteria (4 listed)
- Person with MND, carers, former carers, Health and Social Care Professionals, managers and commissioners
- Ability to engage in focus group or interview or email interview
- Person with MND, carers, former carers, Health and Social Care Professionals, managers and commissioners
- Ability to engage in an observations and interviews
Key exclusion criteria (3 listed)
- no exclusion criteria
- WS2
- no exclusion criteria
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Not applicable- observational studyMND-Together tool will be informed by the findings from this study | Other | – |
Primary outcome
Number of barriers and facilitators for capability, opportunity and motivation (COM-B)
Time frame: February 2026- February 2027
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2026.
- Individual participant dataSharing planned: Yes. The pseudo-anonymised data, and analysis output will be uploaded to the University of Sheffield data repository, ORDA, and stored for 10 years as per the University of Sheffield Retention Schedule. The data will be embargoed until the study has been published in a peer-reviewed journal and will be available thereafter to other researchers upon reasonable request to the CI.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Liam Knox, PhD principal investigator
University of Sheffield
Chris McDermott, MBChB, FRCP, PhD principal investigator
University of Sheffield
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of MND (Motor Neurone DIsease), run by University of Sheffield at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 6 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Liam Knox, PhD (+441142222291, l.knox@sheffield.ac.uk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of barriers and facilitators for capability, opportunity and motivation (COM-B) (time frame: February 2026- February 2027). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2026.