StrokeNCT07405593
Head Up Position and Murottal Therapy in Stroke Patients
A study testing Combination of 30 Degree Head Up and Murottal Therapy in people with Stroke, run by Universitas Muhammadiyah Surakarta at 1 site in Indonesia.
Trial summary
This study aims to evaluate the effects of a combination of a 30-degree head-up position and murottal therapy on physiological and symptom outcomes in stroke patients. The intervention is expected to influence blood pressure, pulse rate, respiratory rate, pain level, and the incidence of projectile vomiting. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke
- What is being tested?
- Combination of 30 Degree Head Up and Murottal Therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 112 participants
- Where
- 1 siteIndonesia
- Study dates
- 1 Mar 2026to 30 Jun 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients with a medical diagnosis of stroke (hemorrhagic and non-hemorrhagic).
- Patients with systolic blood pressure above 150 mmHg.
- Somnolence (GCS ≥ 9).
- Muslim.
- Patients without hearing impairment.
- Willingness to participate and sign informed consent.
Who cannot join
- Patients who are non-Muslim.
- Patients with decreased consciousness (GCS < 9).
- Patients with heart problems.
- Patients with psychiatric disorders.
- Patients receiving sedative therapy during the study.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Indonesia1 site
Rumah Sakit Indriati Solo Baru
Sukoharjo, Central Java, 57571
Rosalia Dian Arsyta Putri, S.Kep.,Ns, M.Kep, 02715722000 ext. 844, rosalia.dian@ymail.com
Kristanti Indah Saraswati, S.Kep.,Ns, M.Kes, 02715722000 ext. 837, kristanti.indah@yahoo.com
About this study
Official title: The Combination Model of 30 Degree Head Up and Murottal Therapy on Blood Pressure, Pulse Rate, Respiratory Rate, Pain Degree, and Projectile Vomiting in Stroke Patients
This study aims to evaluate the effects of a combination of a 30-degree head-up position and murottal therapy on physiological and symptom outcomes in stroke patients. The intervention is expected to influence blood pressure, pulse rate, respiratory rate, pain level, and the incidence of projectile vomiting. Stroke patients will receive standard care with the addition of the combined intervention. The results of this study may support non-pharmacological nursing interventions to improve patient comfort and clinical stability.
Read the detailed description
Stroke patients often experience physiological instability and discomfort, including changes in blood pressure, pulse rate, respiratory rate, pain, and nausea or vomiting. Non-pharmacological nursing interventions are needed to support patient comfort and clinical stability during acute care. Head-up positioning and murottal therapy are commonly used supportive interventions in nursing practice, but evidence regarding their combined effects remains limited.
This study aims to evaluate the effects of a combination of a 30-degree head-up position and murottal therapy on blood pressure, pulse rate, respiratory rate, pain degree, and projectile vomiting in stroke patients. The study involves stroke patients receiving standard medical and nursing care, with the addition of the combined intervention as part of supportive nursing management.
The head-up position will be applied at a 30-degree angle, while murottal therapy will be delivered through 30-minute audio recitation during for 3 days. Physiological parameters and symptom outcomes will be measured before and after the intervention according to the study protocol. The findings of this study are expected to contribute evidence for the use of simple, non-pharmacological nursing interventions to improve comfort and physiological responses in stroke patients.
- Conditions
- Stroke
- Being tested
- Combination of 30 Degree Head Up and Murottal Therapy, Standard Care (in control arm)
- Keywords
- Head Up, Murottal Therapy
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Combination of 30 Degree Head Up and Murottal TherapyOther
Participants in this group received a combination of two non-pharmacological interventions during the study period. First, participants were positioned with their heads elevated at a 30-degree angle while lying in bed to support physiological stability, including monitoring of blood pressure, pulse rate, respiratory rate, pain level, and projectile vomiting. Second, participants listened to Quranic recitation (murottal therapy) via audio recording in a quiet environment. Both interventions were administered simultaneously. Intervention sessions lasted 30 minutes for 3 days (a consistent duration and frequency for all participants in this group). Outcomes such as vital signs, pain level, and episodes of severe vomiting were monitored before and after the intervention period.
Standard Care (in control arm)Other
Participants in this arm receive standard nursing care according to the hospital protocol without additional head-up positioning or murottal therapy. Standard care includes routine monitoring of vital signs, medication administration, and basic supportive nursing interventions.
| Study group | Role | What they receive |
|---|---|---|
| Combination of 30-Degree Head-Up Positioning and Murottal Therapy | Experimental | Participants receive a combination of 30-degree head-up positioning and murottal therapy in addition to standard nursing care during the intervention period. Receives: Other: Combination of 30 Degree Head Up and Murottal Therapy |
| Standard Care | Active comparator | Participants receive standard nursing care according to the hospital's clinical protocol without the addition of head-up positioning or murottal therapy. Receives: Other: Standard Care (in control arm) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Blood Pressure
Change in systolic and diastolic blood pressure from baseline to after completion of the 3-day intervention.
Measured: Baseline and after completion of the 3-day intervention
Pulse Rate
Change in pulse rate from baseline to after completion of the 3-day intervention.
Measured: Baseline and after completion of the 3-day intervention
Respiratory Rate
Change in respiratory rate from baseline to after completion of the 3-day intervention
Measured: Baseline and after completion of the 3-day intervention
Pain Degree
Change in pain score measured using the Critical-Care Pain Observation Tool (CPOT; range 0-8), where higher scores indicate more severe pain, from baseline to after completion of the 3-day intervention.
Measured: Baseline and after completion of the 3-day intervention
Projectile Vomiting
Change in nausea and vomiting severity measured using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR; range 0-32), where higher scores indicate more severe symptoms, from baseline to after completion of the 3-day intervention.
Measured: Baseline and after completion of the 3-day intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Feb 2026
- Study start1 Mar 2026 (estimated)
- Primary completion31 May 2026 (estimated)
- Study completion30 Jun 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- Participants are assigned in parallel to an intervention group receiving 30-degree head-up positioning and murottal therapy or to a control group receiving standard care.
- Masking
- None (open label)
- Enrolment
- 112 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Universitas Muhammadiyah Surakarta
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fila Diana Nurhayati, Universitas Muhammadiyah Surakarta
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07405593
- Sponsor's protocol ID
- FDN-HU-MUROTTAL-STROKE-2026
- Status last verified
- Feb 2026
- First submitted
- 26 Jan 2026
- Last updated
- 12 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Combination Model of 30 Degree Head Up and Murottal Therapy on Blood Pressure, Pulse Rate, Respiratory Rate, Pain Degree, and Projectile Vomiting in Stroke Patients
- ClinicalTrials.gov ID
- NCT07405593
- Acronym / sponsor ID
- FDN-HU-MUROTTAL-STROKE-2026
- Conditions
- Stroke
- Keywords
- Head Up, Murottal Therapy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 112 participants (estimated)
- Lead sponsor
- Universitas Muhammadiyah SurakartaUniversity, hospital or other
- Study start
- 1 Mar 2026 (estimated)
- Primary completion
- 31 May 2026 (estimated)
- Study completion
- 30 Jun 2026 (estimated)
- First posted
- 12 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effects of a combination of a 30-degree head-up position and murottal therapy on physiological and symptom outcomes in stroke patients. The intervention is expected to influence blood pressure, pulse rate, respiratory rate, pain level, and the incidence of projectile vomiting. Stroke patients will receive standard care with the addition of the combined intervention. The results of this study may support non-pharmacological nursing interventions to improve patient comfort and clinical stability.
Detailed description
Stroke patients often experience physiological instability and discomfort, including changes in blood pressure, pulse rate, respiratory rate, pain, and nausea or vomiting. Non-pharmacological nursing interventions are needed to support patient comfort and clinical stability during acute care. Head-up positioning and murottal therapy are commonly used supportive interventions in nursing practice, but evidence regarding their combined effects remains limited.
This study aims to evaluate the effects of a combination of a 30-degree head-up position and murottal therapy on blood pressure, pulse rate, respiratory rate, pain degree, and projectile vomiting in stroke patients. The study involves stroke patients receiving standard medical and nursing care, with the addition of the combined intervention as part of supportive nursing management.
The head-up position will be applied at a 30-degree angle, while murottal therapy will be delivered through 30-minute audio recitation during for 3 days. Physiological parameters and symptom outcomes will be measured before and after the intervention according to the study protocol. The findings of this study are expected to contribute evidence for the use of simple, non-pharmacological nursing interventions to improve comfort and physiological responses in stroke patients.
Study design
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Participants are assigned in parallel to an intervention group receiving 30-degree head-up positioning and murottal therapy or to a control group receiving standard care.
| Arm | Type | Receives |
|---|---|---|
| Combination of 30-Degree Head-Up Positioning and Murottal Therapy | Experimental | Other: Combination of 30 Degree Head Up and Murottal TherapyParticipants receive a combination of 30-degree head-up positioning and murottal therapy in addition to standard nursing care during the intervention period. |
| Standard Care | Active comparator | Other: Standard Care (in control arm)Participants receive standard nursing care according to the hospital's clinical protocol without the addition of head-up positioning or murottal therapy. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Patients with a medical diagnosis of stroke (hemorrhagic and non-hemorrhagic).
- Patients with systolic blood pressure above 150 mmHg.
- Somnolence (GCS ≥ 9).
- Muslim.
- Patients without hearing impairment.
Key exclusion criteria (5 listed)
- Patients who are non-Muslim.
- Patients with decreased consciousness (GCS < 9).
- Patients with heart problems.
- Patients with psychiatric disorders.
- Patients receiving sedative therapy during the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Combination of 30 Degree Head Up and Murottal TherapyParticipants in this group received a combination of two non-pharmacological interventions during the study period. First, participants were positioned with their heads elevated at a 30-degree angle while lying in bed to support physiological stability, including monitoring of blood pressure, pulse rate, respiratory rate, pain level, and projectile vomiting. Second, participants listened to Quranic recitation (murottal therapy) via audio recording in a quiet environment. Both interventions were administered simultaneously. Intervention sessions lasted 30 minutes for 3 days (a consistent duration and frequency for all participants in this group). Outcomes such as vital signs, pain level, and episodes of severe vomiting were monitored before and after the intervention period. | Other | Combination of 30-Degree Head-Up Positioning and Murottal Therapy |
| Standard Care (in control arm)Participants in this arm receive standard nursing care according to the hospital protocol without additional head-up positioning or murottal therapy. Standard care includes routine monitoring of vital signs, medication administration, and basic supportive nursing interventions. | Other | Standard Care |
Primary outcome
Blood Pressure
Time frame: Baseline and after completion of the 3-day intervention
Change in systolic and diastolic blood pressure from baseline to after completion of the 3-day intervention.
Pulse Rate
Time frame: Baseline and after completion of the 3-day intervention
Change in pulse rate from baseline to after completion of the 3-day intervention.
Respiratory Rate
Time frame: Baseline and after completion of the 3-day intervention
Change in respiratory rate from baseline to after completion of the 3-day intervention
Pain Degree
Time frame: Baseline and after completion of the 3-day intervention
Change in pain score measured using the Critical-Care Pain Observation Tool (CPOT; range 0-8), where higher scores indicate more severe pain, from baseline to after completion of the 3-day intervention.
Projectile Vomiting
Time frame: Baseline and after completion of the 3-day intervention
Change in nausea and vomiting severity measured using the Rhodes Index of Nausea, Vomiting, and Retching (RINVR; range 0-32), where higher scores indicate more severe symptoms, from baseline to after completion of the 3-day intervention.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Feb 2026.
- Intracranial Pressure Monitoring and Management in Aneurysmal Subarachnoid HemorrhageLink provided by the sponsor.
- Adherence to Head-of-Bed Elevation in Traumatic Brain Injury: An Audit.Link provided by the sponsor.
- The Effect of Listening to Holy Quran Recital on Pain and Length of Stay Post-CABG: A Randomized Control TrialLink provided by the sponsor.
- Interdisciplinary Neurosurgery : Advanced Techniques and Case Management Position-dependent hemodynamic changes in neurosurgery patients : A narrative review.Link provided by the sponsor.
- Nausea and vomiting in pregnancy ( NVP ) in Chinese pregnant women : a cross-sectional studyLink provided by the sponsor.
- Associations between computed tomography markers of cerebral small vessel disease and hemorrhagic transformation after intravenous thrombolysis in acute ischemic stroke patients.Link provided by the sponsor.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Combination of 30 Degree Head Up and Murottal Therapy in people with Stroke, run by Universitas Muhammadiyah Surakarta at 1 site in Indonesia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 12 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Indonesia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Fila Diana Nurhayati, S.Kep.,Ns (+6281228527848, j218250001@student.ums.ac.id), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Blood Pressure (time frame: Baseline and after completion of the 3-day intervention). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Feb 2026.