Smoking CessationNCT07420621
Preliminary Effectiveness of Enhanced Text Message + Incentives
A study testing Text Messages and Incentives in people with Smoking Cessation and Pregnancy, run by University of Kansas Medical Center at 1 site in United States.
Trial summary
This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives. The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. Read more about this study
- Who is it for?
- Ages 18 years and older, women only
- Conditions the study is for
- Smoking Cessation, Pregnancy
- What is being tested?
- Text Messages and Incentives
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteUnited States
- Study dates
- 9 Apr 2026to 29 Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Pregnant women aged: 18+
- Enrolled in the Special Supplemental Nutrition Program for women, Infants, and Children (WIC) or Medicaid (or applied/applying)
- Self-reported current daily smokers
- Able to communicate in English
- Access to a mobile phone capable of receiving text messages
Who cannot join
- Not at all interested in quitting
- Smoke less than 24 days in the past month
- Greater than 30 weeks gestation
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Kansas Medical Center
Kansas City, Kansas, 66160
Taneisha Scheuermann, PhD, 913-588-2641, tscheuermann@kumc.edu
Taneisha Scheuermann, PhD
About this study
Official title: Preliminary Studies on Implementation of Smoking Cessation Interventions for Low-Income Women
This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives.
The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. text message only (control).
Read the detailed description
Pregnant women who smoke and their babies are exposed to known carcinogens and smoking is associated with adverse maternal and birth outcomes. Low-income pregnant women are particularly at risk because they have higher smoking rates and are less likely to quit. Despite continued smoking, most pregnant smokers do not receive smoking cessation counseling and only one in 10 receive referrals to cessation services or follow-up care. Incentives for smoking cessation yield the highest effect sizes of any intervention for pregnant women. Most prior studies evaluating incentives for smoking cessation in this population have used time and resource-intensive in-person visits to verify abstinence for contingent reinforcement. The long-term goal of this research is to reduce the burden of tobacco use by developing and evaluating a highly scalable, effective intervention to support smoking cessation during pregnancy.
- Conditions
- Smoking Cessation, Pregnancy
- Being tested
- Text Messages, Incentives
- Keywords
- Smoking Cessation, Maternal Health
- Medical subject headings
- Smoking Cessation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Text MessagesBehavioural
Intervention Component - Text messages (SmokeFreeTXT library with pregnancy related messages) participants will receive scheduled messages to support quitting and prevent relapse.
IncentivesBehavioural
Incentives for abstinence - Weeks 1-4; 8; 12: Twice daily CO assessments with verification sent via text-message. Participants will receive daily incentives ranging each day of smoking abstinence.
| Study group | Role | What they receive |
|---|---|---|
| Text Messaging + Incentives | Experimental | Participants in this arm will receive a combination of text messages designed to support smoking cessation and escalating financial incentives contingent on biochemically-verified smoking abstinence (exhaled carbon monoxide). Receives: Behavioral: Text Messages; Behavioral: Incentives |
| Text Messaging Only | Active comparator | Participants in this arm will receive the same text messaging program as in Arm 1, but without the financial incentives contingent on abstinence. Receives: Behavioral: Text Messages |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility of Intervention
Retention rate.
Measured: 12 weeks post-randomization
Smoking Abstinence
Biochemically verified smoking abstinence (exhaled CO)
Measured: 12 weeks post-randomization
Acceptability of Intervention
Participant ratings of acceptability.
Measured: 12 weeks post-randomization
Secondary outcomes (1)
Smoking Abstinence
Exhaled CO
Measured: 26 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Feb 2026
- Study start9 Apr 2026
- Primary completion23 Oct 2026 (estimated)
- Study completion29 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Smoking CessationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Kansas Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of General Medical Sciences (NIGMS)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07420621
- Sponsor's protocol ID
- STUDY00149204
- Status last verified
- Jul 2026
- First submitted
- 12 Feb 2026
- Last updated
- 8 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Potential for de-identification given small sample size.
Study at a glance
From the registry record, last updated by the sponsor on 8 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Preliminary Studies on Implementation of Smoking Cessation Interventions for Low-Income Women
- ClinicalTrials.gov ID
- NCT07420621
- Acronym / sponsor ID
- STUDY00149204
- Conditions
- Smoking Cessation, Pregnancy
- Keywords
- Smoking Cessation, Maternal Health
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University of Kansas Medical CenterUniversity, hospital or other
- Collaborators
- National Institute of General Medical Sciences (NIGMS)
- Study start
- 9 Apr 2026 (actual)
- Primary completion
- 23 Oct 2026 (estimated)
- Study completion
- 29 Jan 2027 (estimated)
- First posted
- 19 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives.
The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. text message only (control).
Detailed description
Pregnant women who smoke and their babies are exposed to known carcinogens and smoking is associated with adverse maternal and birth outcomes. Low-income pregnant women are particularly at risk because they have higher smoking rates and are less likely to quit. Despite continued smoking, most pregnant smokers do not receive smoking cessation counseling and only one in 10 receive referrals to cessation services or follow-up care. Incentives for smoking cessation yield the highest effect sizes of any intervention for pregnant women. Most prior studies evaluating incentives for smoking cessation in this population have used time and resource-intensive in-person visits to verify abstinence for contingent reinforcement. The long-term goal of this research is to reduce the burden of tobacco use by developing and evaluating a highly scalable, effective intervention to support smoking cessation during pregnancy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Text Messaging + Incentives | Experimental | Behavioral: Text Messages, Behavioral: IncentivesParticipants in this arm will receive a combination of text messages designed to support smoking cessation and escalating financial incentives contingent on biochemically-verified smoking abstinence (exhaled carbon monoxide). |
| Text Messaging Only | Active comparator | Behavioral: Text MessagesParticipants in this arm will receive the same text messaging program as in Arm 1, but without the financial incentives contingent on abstinence. |
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Pregnant women aged: 18+
- Enrolled in the Special Supplemental Nutrition Program for women, Infants, and Children (WIC) or Medicaid (or applied/applying)
- Self-reported current daily smokers
- Able to communicate in English
- Access to a mobile phone capable of receiving text messages
Key exclusion criteria (3 listed)
- Not at all interested in quitting
- Smoke less than 24 days in the past month
- Greater than 30 weeks gestation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Text MessagesIntervention Component - Text messages (SmokeFreeTXT library with pregnancy related messages) participants will receive scheduled messages to support quitting and prevent relapse. | Behavioural | Text Messaging + Incentives, Text Messaging Only |
| IncentivesIncentives for abstinence - Weeks 1-4; 8; 12: Twice daily CO assessments with verification sent via text-message. Participants will receive daily incentives ranging each day of smoking abstinence. | Behavioural | Text Messaging + Incentives |
Primary outcome
Feasibility of Intervention
Time frame: 12 weeks post-randomization
Retention rate.
Smoking Abstinence
Time frame: 12 weeks post-randomization
Biochemically verified smoking abstinence (exhaled CO)
Acceptability of Intervention
Time frame: 12 weeks post-randomization
Participant ratings of acceptability.
1 secondary outcome
Smoking Abstinence
Time frame: 26 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jul 2026.
- Individual participant dataSharing planned: Undecided. Potential for de-identification given small sample size.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Text Messages and Incentives in people with Smoking Cessation and Pregnancy, run by University of Kansas Medical Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 8 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility of Intervention (time frame: 12 weeks post-randomization). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jul 2026; AzTrials last refreshed its copy on 31 Oct 2026.