Iliopsoas SyndromeNCT07426601
Eccentric Biased Exercises Effect on Functional Outcomes in Iliopsoas Tendonitis
A study testing ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS in people with Iliopsoas Syndrome and Eccentric Exercise Training, run by Riphah International University at 1 site in Pakistan.
Trial summary
Hip and pelvis injuries represent 2-5% of all injuries. Among these injuries, groin pain is the most common finding. The most common injuries in the hip, pelvis, and thigh area are musculotendinous, (eg, quadriceps strain, adductor tendinitis) and, less commonly, iliopsoas tendinitis). Read more about this study
- Who is it for?
- Ages 20 to 45 years
- Conditions the study is for
- Iliopsoas Syndrome, Eccentric Exercise Training
- What is being tested?
- ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 44 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Jan 2025to 22 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patient with age group 20 to 45
- Male ,female and transgenders.
- Patient with positive Thomas test for Iliopsoas tightness.
- Patient with positive left Ober test for ITB tightness.
- Patient with significant weakness (in MMT scores) of all hip musculature
- Patient with groin pain on the resisted side will be included with average 4-7 .
Who cannot join
- Patient with severe osteoarthritis.
- patient with recent history of trauma.
- patient with any fracture of hip and pelvis.
- patient with any signs of infection in the hip or groin region and will represent with warmth,fever,redness.
- Patients with other severe medical conditions like high vascular diseases should be contraindicated.
- Patient with recent surgery of hip.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Riphah International University
Lahore, Punjab Province, 54000
About this study
Official title: Effect of Eccentric Biased Exercises on Pain, Range of Motion and Quality of Life in Iliopsoas Tendonitis.
Hip and pelvis injuries represent 2-5% of all injuries. Among these injuries, groin pain is the most common finding. The most common injuries in the hip, pelvis, and thigh area are musculotendinous, (eg, quadriceps strain, adductor tendinitis) and, less commonly, iliopsoas tendinitis). Iliopsoas tendonitis is an inflammation of the tendon or area surrounding the tendon. Major causes of iliopsoas tendinitis are acute trauma and overuse resulting from repetitive hip flexion. Patients often present with anterior hip or groin pain of insidious onset. Initially, the patient may note pain after the onset of aggravating activity with resolution soon afterward.
The hip may be held in slight flexion and external rotation to ease tension on the musculotendinous unit. The patient's gait may demonstrate a shortened stride length on the affected side and increased knee flexion in the heel strike and midstance phases.This study aims to determine effects of eccentric biased exercises on pain ,ROM and quality of life in patients with iliopsoas tendonitis.
Read more
This Randomised controlled trial will be conducted at Riphah Rehab Training and Research Center in Lahore over time span of 9-month period. A sample size of 44 Participants age 20 to 55 meeting the inclusion criteria will be selected informed consent will be signed by the participants. Participants will be divided into two groups .
Group A will be controlled group receiving the standard physical therapy. Group B will be experimental group which will receive eccentric biased exercises. Outcome measures will be pain measured by Numeric Pain Rating scale, Range of Motion will be assessed by universal goniometer and quality of Life will be measured by HAGOS Score. Inclusion criteria include patients within age group 20-55 both male, female and trangenders included who have pain in hip groin region Exclusion criteria Include patients with any sign of inflammation ,severe pain ,trauma and fracture are excluded. Data will be analyzed using IBMM SPSS 25.0
Read the detailed description
Iliopsoas tendonitis is known to be an inflammatory condition of the iliopsoas tendon, this tendon connects the iliopsoas muscle to the hip bone and have a key role in hip flexion movement, inflammation of this tendon results in groin pain that causes significant pain and impaired mobility. Inflammation of this tendon is usually due to overuse injury, repetitive movement on hip joint or trauma. The current literatures suggest less prevalence of iliopsoas tendonitis and showed it as an uncommon condition because it is most often overlapped with the symptoms of other hip pathologies, especially anterior hip and groin pain. Early assessment and appropriate physiotherapy management is essential for recovery.
Objective: To determine the effects of Eccentric biased exercises on pain, range of motion and quality of life in patients with Iliopsoas Tendonitis.
Methods: A randomized clinical trial was conducted at Riphah Rehabilitation Clinic Lahore on 44 participants. Participants were assigned randomly into two groups: Group A received standardized physical therapy and Group B received standardized physical therapy combined with eccentric biased exercises. Both groups underwent 3 therapeutic appointments a week for a course of 6-weeks. Numeric Pain Rating Scale (NPRS), Universal Goniometer (UG) and HAGOS scale were utilized to determine pain, range of motion and hip related quality of life at baseline and post treatment values were calculated.
- Conditions
- Iliopsoas Syndrome, Eccentric Exercise Training
- Being tested
- ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS
- Keywords
- pain, range of motion, quality of life
- Medical subject headings
- Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITISOther
Experimental: INTERVENTIONAL GROUP Arm Description: ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS he subject assumed the right side lying position with a Perform Better. ● black monster band secured around the left ankle and the other end attached to a sturdy object behind her at about knee height. ● The left hip will be maximally flexed with the knee flexed as well. This start position is similar to a running position. ● To start the exercise, the subject slowly extended the hip, controlling against the pull into hip extension provided by the monster band for a count of "3" while keeping the knee flexed, until the hip was fully extended . ● stretch on the iliopsoas at end range hip extension will be done ● The subject will made a quick concentric contraction to the count of "1" quickly flexed the hip against the resistance of the band to move the left hip into full hip flexion to the start position. ● The subject will be cued not to arch her back and to keep her abdominals engag
| Study group | Role | What they receive |
|---|---|---|
| INTERVENTIONAL GROUP | Experimental | ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS he subject assumed the right side lying position with a Perform Better. ● black monster band secured around the left ankle and the other end attached to a sturdy object behind her at about knee height.
* The left hip will be maximally flexed with the knee flexed as well. This start position is similar to a running position.
* To start the exercise, the subject slowly extended the hip, controlling against the pull into hip extension provided by the monster band for a count of "3" while keeping the knee flexed, until the hip was fully extended .
* stretch on the iliopsoas at end range hip extension will be done
* The subject will made a quick concentric contraction to the count of "1" quickly flexed the hip against the resistance of the band to move the left hip into full hip flexion to the start position.
* The subject will be cued not to arch her back and to keep her abdominals engaged in order to stabilize the spine again Receives: Other: ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS |
| traditional physical therapy | Placebo comparator | traditional physical therapy Description: Rest Icing for 7mins compression Elevation Subacute phase Hip stretches (iliopsoas, piriformis, hamstring, gluteals) Eccentric hip flexion of 15 reps. Lumbo-pelvic dislocation on Swiss ball (pelvic tilting anterior-posterior, medial lateral, clockwise/counter clockwise) Prone and supine core stability exercises ( 3 sets of 20 repetition for each arm and leg for endurance and control) twice per day over the course of 12 weeks pre and post intervention values will be taken on 1st day and after 12 weeks .The patients will be instructed to exercise into moderate pain, 5/10 on VAS which will be tolerated well without increase in the reactivity of the tendon. Receives: Other: ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS |
What is being measured
The primary outcome is the main question the study is designed to answer.
universal goniometer
iometer for Range of Motion Goniometry is the art and science of measuring the joint ranges in each plane of the joint. A goniometer is the most common instrument used to measure range of motion.
Here are some steps for measuring hip flexion with a goniometer:
Have the patient lie on their back Flex the patient's hip while supporting their lower back with your hand Use landmarks on the pelvis to ensure that the measurement doesn't include motion in the lumbar spine Make sure the patient's pelvis is neutral at the beginning and end of the measurement The normal range of motion for hip flexion is 100-120 degrees, depending on the source. .
Measured: 6 weeks
Numeric PAIN RATING SCALE
NPRS used to assess the pain representing the other pain extreme (e.g. "pain as bad as you can imagine" or "worst pain imaginable(21)
The Numeric Pain Rating Scale (NPRS) is an 11-point scale used to measure pain intensity:
0: No pain 1-3: Mild pain 4-6: Moderate pain 7-10: Severe pain
Measured: 6 weeks
HAGOS QUALITY OF LIFE QUESTIONNAIRE
The Copenhagen Hip and Groin Outcome Score is a patient-reported questionnaire that has six discrete subscales to assess Pain (10 items), Symptoms (7 items), Physical function in daily living (5 items), physical function in Sport and Recreation (8 items), Participation in Physical Activities (2 items) and hip and/or groin related Quality of Life (5 items). It has 37 items in total.
Method of Use Six subscales make up the HAGOS questionnaire: Symptoms, Pain, ADL, Sport/Rec, PA, and QOL. Each subscale is rated independently, with a score ranging from 0 to 4 for each item. After the results are added together, the subscale scores are converted to a 0-100 scale. A score of 100 indicates the absence of hip and/or groin issues, while a score of 0 indicates significant hip and/or groin issues. The percentage of the total possible score attained is represented by the scores, which range from 0 to 100. There is no calculation of an overall score; instead, the subscales were examined.
Measured: 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Feb 2026
- Study start10 Jan 2025
- Primary completion10 Nov 2025
- Study completion22 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Iliopsoas SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 44 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Saba Rafique, PhD, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07426601
- Sponsor's protocol ID
- REC/RCR & AHS/24/0184
- Status last verified
- Feb 2026
- First submitted
- 17 Feb 2026
- Last updated
- 23 Feb 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Eccentric Biased Exercises on Pain, Range of Motion and Quality of Life in Iliopsoas Tendonitis.
- ClinicalTrials.gov ID
- NCT07426601
- Acronym / sponsor ID
- REC/RCR & AHS/24/0184
- Conditions
- Iliopsoas Syndrome, Eccentric Exercise Training
- Keywords
- pain, range of motion, quality of life
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 44 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 10 Jan 2025 (actual)
- Primary completion
- 10 Nov 2025 (actual)
- Study completion
- 22 Dec 2025 (actual)
- First posted
- 23 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Hip and pelvis injuries represent 2-5% of all injuries. Among these injuries, groin pain is the most common finding. The most common injuries in the hip, pelvis, and thigh area are musculotendinous, (eg, quadriceps strain, adductor tendinitis) and, less commonly, iliopsoas tendinitis). Iliopsoas tendonitis is an inflammation of the tendon or area surrounding the tendon. Major causes of iliopsoas tendinitis are acute trauma and overuse resulting from repetitive hip flexion. Patients often present with anterior hip or groin pain of insidious onset. Initially, the patient may note pain after the onset of aggravating activity with resolution soon afterward.
The hip may be held in slight flexion and external rotation to ease tension on the musculotendinous unit. The patient's gait may demonstrate a shortened stride length on the affected side and increased knee flexion in the heel strike and midstance phases.This study aims to determine effects of eccentric biased exercises on pain ,ROM and quality of life in patients with iliopsoas tendonitis.
This Randomised controlled trial will be conducted at Riphah Rehab Training and Research Center in Lahore over time span of 9-month period. A sample size of 44 Participants age 20 to 55 meeting the inclusion criteria will be selected informed consent will be signed by the participants. Participants will be divided into two groups .
Group A will be controlled group receiving the standard physical therapy. Group B will be experimental group which will receive eccentric biased exercises. Outcome measures will be pain measured by Numeric Pain Rating scale, Range of Motion will be assessed by universal goniometer and quality of Life will be measured by HAGOS Score. Inclusion criteria include patients within age group 20-55 both male, female and trangenders included who have pain in hip groin region Exclusion criteria Include patients with any sign of inflammation ,severe pain ,trauma and fracture are excluded. Data will be analyzed using IBMM SPSS 25.0
Detailed description
Iliopsoas tendonitis is known to be an inflammatory condition of the iliopsoas tendon, this tendon connects the iliopsoas muscle to the hip bone and have a key role in hip flexion movement, inflammation of this tendon results in groin pain that causes significant pain and impaired mobility. Inflammation of this tendon is usually due to overuse injury, repetitive movement on hip joint or trauma. The current literatures suggest less prevalence of iliopsoas tendonitis and showed it as an uncommon condition because it is most often overlapped with the symptoms of other hip pathologies, especially anterior hip and groin pain. Early assessment and appropriate physiotherapy management is essential for recovery.
Objective: To determine the effects of Eccentric biased exercises on pain, range of motion and quality of life in patients with Iliopsoas Tendonitis.
Methods: A randomized clinical trial was conducted at Riphah Rehabilitation Clinic Lahore on 44 participants. Participants were assigned randomly into two groups: Group A received standardized physical therapy and Group B received standardized physical therapy combined with eccentric biased exercises. Both groups underwent 3 therapeutic appointments a week for a course of 6-weeks. Numeric Pain Rating Scale (NPRS), Universal Goniometer (UG) and HAGOS scale were utilized to determine pain, range of motion and hip related quality of life at baseline and post treatment values were calculated.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| INTERVENTIONAL GROUP | Experimental | Other: ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITISECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS he subject assumed the right side lying position with a Perform Better. ● black monster band secured around the left ankle and the other end attached to a sturdy object behind her at about knee height. * The left hip will be maximally flexed with the knee flexed as well. This start position is similar to a running position. * To start the exercise, the subject slowly extended the hip, controlling against the pull into hip extension provided by the monster band for a count of "3" while keeping the knee flexed, until the hip was fully extended . * stretch on the iliopsoas at end range hip extension will be done * The subject will made a quick concentric contraction to the count of "1" quickly flexed the hip against the resistance of the band to move the left hip into full hip flexion to the start position. * The subject will be cued not to arch her back and to keep her abdominals engaged in order to stabilize the spine again |
| traditional physical therapy | Placebo comparator | Other: ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIStraditional physical therapy Description: Rest Icing for 7mins compression Elevation Subacute phase Hip stretches (iliopsoas, piriformis, hamstring, gluteals) Eccentric hip flexion of 15 reps. Lumbo-pelvic dislocation on Swiss ball (pelvic tilting anterior-posterior, medial lateral, clockwise/counter clockwise) Prone and supine core stability exercises ( 3 sets of 20 repetition for each arm and leg for endurance and control) twice per day over the course of 12 weeks pre and post intervention values will be taken on 1st day and after 12 weeks .The patients will be instructed to exercise into moderate pain, 5/10 on VAS which will be tolerated well without increase in the reactivity of the tendon. |
Who may qualify
- Ages
- 20 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Patient with age group 20 to 45
- Male ,female and transgenders.
- Patient with positive Thomas test for Iliopsoas tightness.
- Patient with positive left Ober test for ITB tightness.
- Patient with significant weakness (in MMT scores) of all hip musculature
Key exclusion criteria (6 listed)
- Patient with severe osteoarthritis.
- patient with recent history of trauma.
- patient with any fracture of hip and pelvis.
- patient with any signs of infection in the hip or groin region and will represent with warmth,fever,redness.
- Patients with other severe medical conditions like high vascular diseases should be contraindicated.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITISExperimental: INTERVENTIONAL GROUP Arm Description: ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS he subject assumed the right side lying position with a Perform Better. ● black monster band secured around the left ankle and the other end attached to a sturdy object behind her at about knee height. ● The left hip will be maximally flexed with the knee flexed as well. This start position is similar to a running position. ● To start the exercise, the subject slowly extended the hip, controlling against the pull into hip extension provided by the monster band for a count of "3" while keeping the knee flexed, until the hip was fully extended . ● stretch on the iliopsoas at end range hip extension will be done ● The subject will made a quick concentric contraction to the count of "1" quickly flexed the hip against the resistance of the band to move the left hip into full hip flexion to the start position. ● The subject will be cued not to arch her back and to keep her abdominals engag | Other | INTERVENTIONAL GROUP, traditional physical therapy |
Primary outcome
universal goniometer
Time frame: 6 weeks
iometer for Range of Motion Goniometry is the art and science of measuring the joint ranges in each plane of the joint. A goniometer is the most common instrument used to measure range of motion. Here are some steps for measuring hip flexion with a goniometer: Have the patient lie on their back Flex the patient's hip while supporting their lower back with your hand Use landmarks on the pelvis to ensure that the measurement doesn't include motion in the lumbar spine Make sure the patient's pelvis is neutral at the beginning and end of the measurement The normal range of motion for hip flexion is 100-120 degrees, depending on the source. .
Numeric PAIN RATING SCALE
Time frame: 6 weeks
NPRS used to assess the pain representing the other pain extreme (e.g. "pain as bad as you can imagine" or "worst pain imaginable(21) The Numeric Pain Rating Scale (NPRS) is an 11-point scale used to measure pain intensity: 0: No pain 1-3: Mild pain 4-6: Moderate pain 7-10: Severe pain
HAGOS QUALITY OF LIFE QUESTIONNAIRE
Time frame: 6 weeks
The Copenhagen Hip and Groin Outcome Score is a patient-reported questionnaire that has six discrete subscales to assess Pain (10 items), Symptoms (7 items), Physical function in daily living (5 items), physical function in Sport and Recreation (8 items), Participation in Physical Activities (2 items) and hip and/or groin related Quality of Life (5 items). It has 37 items in total. Method of Use Six subscales make up the HAGOS questionnaire: Symptoms, Pain, ADL, Sport/Rec, PA, and QOL. Each subscale is rated independently, with a score ranging from 0 to 4 for each item. After the results are added together, the subscale scores are converted to a 0-100 scale. A score of 100 indicates the absence of hip and/or groin issues, while a score of 0 indicates significant hip and/or groin issues. The percentage of the total possible score attained is represented by the scores, which range from 0 to 100. There is no calculation of an overall score; instead, the subscales were examined.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Feb 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Saba Rafique, PhD principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS in people with Iliopsoas Syndrome and Eccentric Exercise Training, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
universal goniometer (time frame: 6 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Feb 2026.