Postoperative PainNCT07426796
Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.
A study testing Ultrasound-guided Posterior Quadratus Lumborum Block. and Ultrasound-guided Quadroiliac Plane Block in people with Postoperative Pain and Cryptorchidism, run by Medipol University at 1 site in Turkey (Türkiye).
Trial summary
This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing unilateral undescended testis surgery. Read more about this study
- Who is it for?
- Ages 1 year to 7 years, men only
- Conditions the study is for
- Postoperative Pain, Cryptorchidism
- What is being tested?
- Ultrasound-guided Posterior Quadratus Lumborum Block. and Ultrasound-guided Quadroiliac Plane Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 16 Feb 2026to 27 Aug 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 year to 7 years
- Men only
- No healthy volunteers
- Child
Who may be able to join
- Male pediatric patients aged 1-7 years.
- ASA physical status I or II.
- Scheduled for unilateral undescended testis surgery.
- Written informed consent obtained.
Who cannot join
- History of neurological deficit or developmental delay.
- Bleeding diathesis or known coagulopathy.
- History of allergy to local anesthetics.
- Infection or skin lesion at the block injection site.
- Congenital spinal anomaly.
- Mental retardation or psychiatric history.
- Liver or kidney dysfunction.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparison of the Effects of Posterior Quadratus Lumborum Block and Quadroiliac Plane Block on Analgesic Consumption in Postoperative Pain Management in Pediatric Patients Undergoing Undescended Testis Surgery
This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing unilateral undescended testis surgery.
Read the detailed description
Lower abdominal surgeries, such as undescended testis repair (orchiopexy), are common in pediatric patients and can cause significant postoperative pain. While Posterior Quadratus Lumborum Block (QLB) is a known technique for somatic and visceral analgesia, the Quadroiliac Plane Block (QIPB) is a newer approach targeting the fascial plane posterior to the iliac bone.
In this prospective, randomized, controlled trial, 70 pediatric patients (ASA I-II, aged 1-7 years) will be randomly assigned to receive either a Posterior QLB or a QIPB under general anesthesia. Both blocks will be performed using ultrasound guidance with 0.5 mL/kg of 0.25% bupivacaine.
The study aims to evaluate and compare the analgesic efficacy of these two techniques. Postoperative pain will be assessed using the FLACC scale. Secondary objectives include comparing the time to first rescue analgesic, total analgesic consumption, and incidence of complications.
- Conditions
- Postoperative Pain, Cryptorchidism
- Being tested
- Ultrasound-guided Posterior Quadratus Lumborum Block., Ultrasound-guided Quadroiliac Plane Block
- Medical subject headings
- Pain, Postoperative, Cryptorchidism
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound-guided Posterior Quadratus Lumborum Block.Procedure or surgery
Patients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the posterior axillary line. The needle will be advanced to the posterior fascial plane of the quadratus lumborum muscle. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected.
Ultrasound-guided Quadroiliac Plane BlockProcedure or surgery
Patients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the level of the iliac crest. The needle will be targeted to the plane where the quadratus lumborum muscle attaches to the iliac bone. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected
| Study group | Role | What they receive |
|---|---|---|
| Posterior QLB Group | Experimental | Patients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the posterior axillary line. The needle will be advanced to the posterior fascial plane of the quadratus lumborum muscle. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected Receives: Procedure: Ultrasound-guided Posterior Quadratus Lumborum Block. |
| QIPB Group | Experimental | Patients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the level of the iliac crest. The needle will be targeted to the plane where the quadratus lumborum muscle attaches to the iliac bone. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected. Receives: Procedure: Ultrasound-guided Quadroiliac Plane Block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain Score (FLACC) at 12 Hours
Pain severity assessed using the Face, Legs, Activity, Cry, Consolability (FLACC) scale. The total score ranges from 0 to 10, where higher scores indicate worse pain.
Measured: 12 hours post-surgery.
Secondary outcomes (4)
Time to First Rescue Analgesic Request.
Time in minutes from surgery completion to the first dose of rescue analgesia.
Measured: Up to 24 hours.
Total Postoperative Analgesic Consumption
Cumulative amount of rescue analgesics consumed (mg).
Measured: 24 hours post-surgery.
Incidence of Postoperative Complications.
Assessment of complications such as urinary retention, motor block, hematoma, or ecchymosis at the injection site.
Measured: Up to 24 hours.
Postoperative Pain Scores (FLACC) at Other Time Points.
Pain severity assessed using the Face, Legs, Activity, Cry, Consolability (FLACC) scale at 30 minutes, 1, 2, 4, 6, and 24 hours. The total score ranges from 0 to 10, where higher scores indicate worse pain.
Measured: 30 minutes, 1, 2, 4, 6, and 24 hours post-surgery.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Feb 2026
- Study start16 Feb 2026
- Primary completion17 Aug 2026
- Study completion27 Aug 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- More trials run by Medipol UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Outcomes assessor
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Medipol University
- Sponsor type
- University, hospital or other
- Collaborators
- Biruni University, Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Responsible party
- Principal investigator, Burak Omur, Medipol University
- Investigators
- Selçuk Alver, Study chair, Biruni UniversityVolkan Özen, Study chair, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul.
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07426796
- Sponsor's protocol ID
- 150, 22.01.2026
- Status last verified
- Sep 2026
- First submitted
- 15 Feb 2026
- Last updated
- 3 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of Posterior Quadratus Lumborum Block and Quadroiliac Plane Block on Analgesic Consumption in Postoperative Pain Management in Pediatric Patients Undergoing Undescended Testis Surgery
- ClinicalTrials.gov ID
- NCT07426796
- Acronym / sponsor ID
- 150, 22.01.2026
- Conditions
- Postoperative Pain, Cryptorchidism
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Medipol UniversityUniversity, hospital or other
- Collaborators
- Biruni University, Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
- Study start
- 16 Feb 2026 (actual)
- Primary completion
- 17 Aug 2026 (actual)
- Study completion
- 27 Aug 2026 (actual)
- First posted
- 23 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing unilateral undescended testis surgery.
Detailed description
Lower abdominal surgeries, such as undescended testis repair (orchiopexy), are common in pediatric patients and can cause significant postoperative pain. While Posterior Quadratus Lumborum Block (QLB) is a known technique for somatic and visceral analgesia, the Quadroiliac Plane Block (QIPB) is a newer approach targeting the fascial plane posterior to the iliac bone.
In this prospective, randomized, controlled trial, 70 pediatric patients (ASA I-II, aged 1-7 years) will be randomly assigned to receive either a Posterior QLB or a QIPB under general anesthesia. Both blocks will be performed using ultrasound guidance with 0.5 mL/kg of 0.25% bupivacaine.
The study aims to evaluate and compare the analgesic efficacy of these two techniques. Postoperative pain will be assessed using the FLACC scale. Secondary objectives include comparing the time to first rescue analgesic, total analgesic consumption, and incidence of complications.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Posterior QLB Group | Experimental | Procedure: Ultrasound-guided Posterior Quadratus Lumborum Block.Patients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the posterior axillary line. The needle will be advanced to the posterior fascial plane of the quadratus lumborum muscle. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected |
| QIPB Group | Experimental | Procedure: Ultrasound-guided Quadroiliac Plane BlockPatients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the level of the iliac crest. The needle will be targeted to the plane where the quadratus lumborum muscle attaches to the iliac bone. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected. |
Who may qualify
- Ages
- 1 year to 7 years
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (4 listed)
- Male pediatric patients aged 1-7 years.
- ASA physical status I or II.
- Scheduled for unilateral undescended testis surgery.
- Written informed consent obtained.
Key exclusion criteria (7 listed)
- History of neurological deficit or developmental delay.
- Bleeding diathesis or known coagulopathy.
- History of allergy to local anesthetics.
- Infection or skin lesion at the block injection site.
- Congenital spinal anomaly.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound-guided Posterior Quadratus Lumborum Block.Patients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the posterior axillary line. The needle will be advanced to the posterior fascial plane of the quadratus lumborum muscle. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected. | Procedure or surgery | Posterior QLB Group |
| Ultrasound-guided Quadroiliac Plane BlockPatients will be placed in the lateral decubitus position. Under ultrasound guidance, the probe will be placed at the level of the iliac crest. The needle will be targeted to the plane where the quadratus lumborum muscle attaches to the iliac bone. A total of 0.5 mL/kg of 0.25% Bupivacaine will be injected | Procedure or surgery | QIPB Group |
Primary outcome
Postoperative Pain Score (FLACC) at 12 Hours
Time frame: 12 hours post-surgery.
Pain severity assessed using the Face, Legs, Activity, Cry, Consolability (FLACC) scale. The total score ranges from 0 to 10, where higher scores indicate worse pain.
4 secondary outcomes
Time to First Rescue Analgesic Request.
Time frame: Up to 24 hours.
Total Postoperative Analgesic Consumption
Time frame: 24 hours post-surgery.
Incidence of Postoperative Complications.
Time frame: Up to 24 hours.
Postoperative Pain Scores (FLACC) at Other Time Points.
Time frame: 30 minutes, 1, 2, 4, 6, and 24 hours post-surgery.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Selçuk Alver study chair
Biruni University
Volkan Özen study chair
Prof. Dr. Cemil Tascioglu City Hospital, Istanbul.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound-guided Posterior Quadratus Lumborum Block. and Ultrasound-guided Quadroiliac Plane Block in people with Postoperative Pain and Cryptorchidism, run by Medipol University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain Score (FLACC) at 12 Hours (time frame: 12 hours post-surgery.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2026.