Cerebral Palsy, HemiplegicNCT07429175
Sensory-Motor Relationship in Unilateral CP
An observational study of Cerebral Palsy, Hemiplegic, run by Ankara University at 1 site in Turkey (Türkiye).
Trial summary
Cerebral palsy (CP) is characterized by many problems related to brain damage. One of these is sensory impairment. Sensory impairments in CP patients can also occur together with motor functions. Read more about this study
- Who is it for?
- Ages 6 to 15 yearsHealthy volunteers can take part
- Conditions the study is for
- Cerebral Palsy, Hemiplegic
- How many people
- 110 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Sep 2024to 30 Nov 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 15 years
- All sexes
- Healthy volunteers accepted
- Child
Study population: Children with unilateral cerebral palsy (CP) who meet the inclusion criteria and who apply to the Physical Medicine and Rehabilitation Department Clinic or Outpatient Clinic of Ankara University Faculty of Medicine, as well as healthy volunteers, will be included in the study.
Who may be able to join
- Children aged 15 with unilateral cerebral palsy (CP)
- Being between Gross Motor Functional Classification System I-IV
- Not having undergone surgery or botulinum toxin application to the affected upper extremity in the last 6 months
- Understanding what is said and being able to follow commands
- The patient or their relatives having completed an informed consent form
Who cannot join
- Having a neurological disease affecting the motor and sensory system other than cerebral palsy
- The participant having a dermatological, vascular, or orthopedic problem in the upper extremity that would prevent assessment
- Having uncorrected vision and hearing problems
- Having autism spectrum disorder and attention deficit hyperactivity disorder
- Having insufficient intelligence level
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Relationship Between Sensory Impairments and Upper Extremity Motor Functions in Children With Unilateral Cerebral Palsy
Cerebral palsy (CP) is characterized by many problems related to brain damage. One of these is sensory impairment. Sensory impairments in CP patients can also occur together with motor functions. Detecting sensory impairments (two-point discrimination, vibration, joint position sense, thermal sensation, stereognosis, graphesthesia) in the arm, forearm, and hand (upper extremity) in CP patients and investigating their relationship with motor functions is important. The aim of this research is to investigate the relationship between upper extremity sensory impairments and motor functions in patients diagnosed with unilateral (affecting one half of the body) CP.
Read the detailed description
The aim of this study is to investigate the relationship between sensory impairments and upper extremity motor functions in patients with unilateral cerebral palsy (CP). It will be planned as a cross-sectional study. The study will include 55 unilateral CP patients and 55 healthy volunteers. Sensory functions evaluated include two-point discrimination, joint position sense, vibration sense, thermal sense, stereognosis, and graphesthesia. Motor functions will be assessed using the Gross Motor Functional Classification System (GMFSS), Hand Skills Classification System (ESCS), Abilhand-Kids scale, Box and Block test, and Nine Hole Peg test. The relationship between sensory parameters and motor functions will be investigated.
- Conditions
- Cerebral Palsy, Hemiplegic
- Keywords
- cerebral palsy, sensory function, motor function
- Medical subject headings
- Cerebral Palsy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patient Group | Children aged 6-15 with unilateral (hemiplegic) cerebral palsy | |
| Healthy Group | Healthy children aged 6-15 |
What is being measured
The primary outcome is the main question the study is designed to answer.
Sensory Function:Two-point discrimination
Two-point discrimination is defined as the ability to distinguish between two simultaneous points of touch, which is most acute in areas of the skin with a high density of touch receptors, such as the fingers and face. The test will be performed using a discriminator device called an esthesiometer.
Measured: Single assessment at baseline (cross-sectional evaluation)
Sensory Function:Joint position sense
Joint position sense is the ability to detect body segment position in space and is commonly used to represent proprioceptive performance.
Measured: Single assessment at baseline (cross-sectional evaluation)
Sensory Function:Vibration
Assessment of vibration sense is the best clinical test of the dorsal column pathway. A low-frequency (128 Hz) tuning fork is applied to bony prominences and the patient (with closed eyes) is asked to report when the vibration starts and stops.
Measured: Single assessment at baseline (cross-sectional evaluation)
Sensory Function:thermal sense
The volunteer's upper extremity is successively touched with tubes filled with hot and cold water, and the volunteer is asked to respond as hot or cold. Thermal sensation is recorded as 'preserved', 'impaired', or 'unable to assess'.
Measured: Single assessment at baseline (cross-sectional evaluation)
Sensory Function:Stereognosis
Without visual or auditory cues, objects are placed in a sequence, and the child is asked to grasp them and identify the name of the object. Each object is awarded '1' point for being correctly identified, and '0' points for not identifying it. Scores ranging from 0 to 6 are recorded.
Measured: Single assessment at baseline (cross-sectional evaluation)
Sensory Function:Graphesthesia
Six different drawings-letters, numbers, circles, and vertical lines-are made on the palm of the volunteer's hand using a blunt pencil, without any visual or auditory stimuli. Each correct drawing earns '1' point, and each incorrect drawing earns '0' points. Scores ranging from 0 to 6 are recorded.
Measured: Single assessment at baseline (cross-sectional evaluation)
Motor Function: Gross Motor Functional Classification System
This classification system consists of 5 levels.
Measured: Single assessment at baseline (cross-sectional evaluation)
Motor Function: Hand Skills Classification System
This classification system consists of 5 levels.
Measured: Single assessment at baseline (cross-sectional evaluation)
Motor Function: Abilhand-Kids Scale
Twenty-one daily activities were evaluated. Participants were asked to rate an activity-which the child attempted to perform independently using both upper extremities-on a scale of 0-42 points.
Measured: Single assessment at baseline (cross-sectional evaluation)
Motor Function: Nine Hole Peg Test
The Nine Hole Peg Test was developed to measure finger dexterity, also known as fine manual dexterity. The test consists of a wooden board with nine holes and nine small sticks designed to be inserted into those holes. The participant is asked to take the sticks from the box one by one with the hand being tested and insert them into the holes as quickly as possible; then, they must remove the sticks one by one and return them to the box.
Measured: Single assessment at baseline (cross-sectional evaluation)
Motor Function: Box and Block Test
The Box and Block Test (BBT) measures unilateral gross manual dexterity. Participants are given 60 seconds to move wooden blocks by hand to the opposite compartment as quickly as possible. At the end of 60 seconds, the number of wooden blocks transferred to the opposite compartment is noted.
Measured: Single assessment at baseline (cross-sectional evaluation)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Feb 2026
- Study start1 Sep 2024
- Primary completion30 Nov 2025
- Study completion30 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cerebral Palsy, HemiplegicStudies of the same condition, open and under way.
- More trials run by Ankara UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 110 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ankara University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Birkan Sonel Tur, Ankara University
- Investigators
- Birkan Sonel Tur, Professor, Principal investigator, Ankara University, Faculty of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07429175
- Sponsor's protocol ID
- İ07-512-24
- Status last verified
- Feb 2026
- First submitted
- 27 Jan 2026
- Last updated
- 24 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Relationship Between Sensory Impairments and Upper Extremity Motor Functions in Children With Unilateral Cerebral Palsy
- ClinicalTrials.gov ID
- NCT07429175
- Acronym / sponsor ID
- İ07-512-24
- Conditions
- Cerebral Palsy, Hemiplegic
- Keywords
- cerebral palsy, sensory function, motor function
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 110 participants (actual)
- Lead sponsor
- Ankara UniversityUniversity, hospital or other
- Study start
- 1 Sep 2024 (actual)
- Primary completion
- 30 Nov 2025 (actual)
- Study completion
- 30 Nov 2025 (actual)
- First posted
- 24 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cerebral palsy (CP) is characterized by many problems related to brain damage. One of these is sensory impairment. Sensory impairments in CP patients can also occur together with motor functions. Detecting sensory impairments (two-point discrimination, vibration, joint position sense, thermal sensation, stereognosis, graphesthesia) in the arm, forearm, and hand (upper extremity) in CP patients and investigating their relationship with motor functions is important. The aim of this research is to investigate the relationship between upper extremity sensory impairments and motor functions in patients diagnosed with unilateral (affecting one half of the body) CP.
Detailed description
The aim of this study is to investigate the relationship between sensory impairments and upper extremity motor functions in patients with unilateral cerebral palsy (CP). It will be planned as a cross-sectional study. The study will include 55 unilateral CP patients and 55 healthy volunteers. Sensory functions evaluated include two-point discrimination, joint position sense, vibration sense, thermal sense, stereognosis, and graphesthesia. Motor functions will be assessed using the Gross Motor Functional Classification System (GMFSS), Hand Skills Classification System (ESCS), Abilhand-Kids scale, Box and Block test, and Nine Hole Peg test. The relationship between sensory parameters and motor functions will be investigated.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Patient Group | – | –Children aged 6-15 with unilateral (hemiplegic) cerebral palsy |
| Healthy Group | – | –Healthy children aged 6-15 |
Who may qualify
- Ages
- 6 to 15 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
- Study population
- Children with unilateral cerebral palsy (CP) who meet the inclusion criteria and who apply to the Physical Medicine and Rehabilitation Department Clinic or Outpatient Clinic of Ankara University Faculty of Medicine, as well as healthy volunteers, will be included in the study.
Key inclusion criteria (5 listed)
- Children aged 15 with unilateral cerebral palsy (CP)
- Being between Gross Motor Functional Classification System I-IV
- Not having undergone surgery or botulinum toxin application to the affected upper extremity in the last 6 months
- Understanding what is said and being able to follow commands
- The patient or their relatives having completed an informed consent form
Key exclusion criteria (5 listed)
- Having a neurological disease affecting the motor and sensory system other than cerebral palsy
- The participant having a dermatological, vascular, or orthopedic problem in the upper extremity that would prevent assessment
- Having uncorrected vision and hearing problems
- Having autism spectrum disorder and attention deficit hyperactivity disorder
- Having insufficient intelligence level
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Sensory Function:Two-point discrimination
Time frame: Single assessment at baseline (cross-sectional evaluation)
Two-point discrimination is defined as the ability to distinguish between two simultaneous points of touch, which is most acute in areas of the skin with a high density of touch receptors, such as the fingers and face. The test will be performed using a discriminator device called an esthesiometer.
Sensory Function:Joint position sense
Time frame: Single assessment at baseline (cross-sectional evaluation)
Joint position sense is the ability to detect body segment position in space and is commonly used to represent proprioceptive performance.
Sensory Function:Vibration
Time frame: Single assessment at baseline (cross-sectional evaluation)
Assessment of vibration sense is the best clinical test of the dorsal column pathway. A low-frequency (128 Hz) tuning fork is applied to bony prominences and the patient (with closed eyes) is asked to report when the vibration starts and stops.
Sensory Function:thermal sense
Time frame: Single assessment at baseline (cross-sectional evaluation)
The volunteer's upper extremity is successively touched with tubes filled with hot and cold water, and the volunteer is asked to respond as hot or cold. Thermal sensation is recorded as 'preserved', 'impaired', or 'unable to assess'.
Sensory Function:Stereognosis
Time frame: Single assessment at baseline (cross-sectional evaluation)
Without visual or auditory cues, objects are placed in a sequence, and the child is asked to grasp them and identify the name of the object. Each object is awarded '1' point for being correctly identified, and '0' points for not identifying it. Scores ranging from 0 to 6 are recorded.
Sensory Function:Graphesthesia
Time frame: Single assessment at baseline (cross-sectional evaluation)
Six different drawings-letters, numbers, circles, and vertical lines-are made on the palm of the volunteer's hand using a blunt pencil, without any visual or auditory stimuli. Each correct drawing earns '1' point, and each incorrect drawing earns '0' points. Scores ranging from 0 to 6 are recorded.
Motor Function: Gross Motor Functional Classification System
Time frame: Single assessment at baseline (cross-sectional evaluation)
This classification system consists of 5 levels.
Motor Function: Hand Skills Classification System
Time frame: Single assessment at baseline (cross-sectional evaluation)
This classification system consists of 5 levels.
Motor Function: Abilhand-Kids Scale
Time frame: Single assessment at baseline (cross-sectional evaluation)
Twenty-one daily activities were evaluated. Participants were asked to rate an activity-which the child attempted to perform independently using both upper extremities-on a scale of 0-42 points.
Motor Function: Nine Hole Peg Test
Time frame: Single assessment at baseline (cross-sectional evaluation)
The Nine Hole Peg Test was developed to measure finger dexterity, also known as fine manual dexterity. The test consists of a wooden board with nine holes and nine small sticks designed to be inserted into those holes. The participant is asked to take the sticks from the box one by one with the hand being tested and insert them into the holes as quickly as possible; then, they must remove the sticks one by one and return them to the box.
Motor Function: Box and Block Test
Time frame: Single assessment at baseline (cross-sectional evaluation)
The Box and Block Test (BBT) measures unilateral gross manual dexterity. Participants are given 60 seconds to move wooden blocks by hand to the opposite compartment as quickly as possible. At the end of 60 seconds, the number of wooden blocks transferred to the opposite compartment is noted.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Feb 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Birkan Sonel Tur, Professor principal investigator
Ankara University, Faculty of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cerebral Palsy, Hemiplegic, run by Ankara University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Sensory Function:Two-point discrimination (time frame: Single assessment at baseline (cross-sectional evaluation)). The study lists 11 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Feb 2026.