Upper Cross SyndromeNCT07435519
Effects of Klapp Method in Upper Cross Syndrome Patients
A study testing Klapp Method and Conventional treatment in people with Upper Cross Syndrome, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study was conducted to determine the effects of Klapp Method on posture, craniovertebral angle and disability in upper cross syndrome patients. Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Upper Cross Syndrome
- What is being tested?
- Klapp Method and Conventional treatment
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 sitePakistan
- Study dates
- Feb 2026to 18 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Both genders were included
- Participants were between the ages of 18 to 40.
- The craniovertebral angle was less than or equal to 50 degrees
- The REEDCO Posture Assessment Scale of 59% or less.
Who cannot join
- Patients that had a history of vascular syndrome, cervical spine infection, trauma, surgery, or cervical spine damage
- Patients with inflammatory arthritis (such as rheumatoid arthritis or ankylosing spondylitis)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Effects of Klapp Method on Posture, Craniovertebral Angle and Disability in Upper Cross Syndrome Patients
This study was conducted to determine the effects of Klapp Method on posture, craniovertebral angle and disability in upper cross syndrome patients.
- Conditions
- Upper Cross Syndrome
- Being tested
- Klapp Method, Conventional treatment
- Keywords
- Craniovertebral Angle, Klapp Method, Neck Disability Index, Posture, Upper Cross Syndrome
- Medical subject headings
- Oculocerebral hypopigmentation syndrome type Preus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Klapp MethodOther
Klapp Method: 3 sessions/week for 6 weeks Four-point walk followed by two-point walk \& back walk Breathing exercise from a kneeling position Simple bounce glide with simultaneous breathing Bunny hop
Breathing exercise from a quadrupedal position:
Greetings
Conventional treatmentOther
Conventional Physical Therapy Treatment : 3 sessions/week for 6 weeks Hot pack 10 min Stretching exercises for Levator scapulae 3 sets for 30 sec hold each. Upper trapezius 3 sets for 30 sec hold each. Pectoralis stretches: 3 sets for 30 sec hold each.
Strengthening was given to :
Upper, Middle and Lower Trapezius: 10 repetitions 3 sets. Serratus anterior: 10 repetitions and 3 sets. Infraspinatus: 10 repetitions 3 sets. Deep neck flexors: 30 seconds hold 3 sets.
| Study group | Role | What they receive |
|---|---|---|
| Klapp Method with Conventional Physical Therapy treatment | Experimental | Not described Receives: Other: Klapp Method; Other: Conventional treatment |
| Conventional Physical Therapy Treatment | Active comparator | Not described Receives: Other: Conventional treatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Craniovertebral Angle
Universal Goniometer is utilized to measure the craniovertebral angle. An angle between 50 to 53 degrees is considered normal
Measured: From enrollment to the end of treatment at 6 weeks
Reedco Posture Score
Reedco Posture score is used to assess posture. The RPS includes personal information about the person being evaluated, along with a scoring system for various body parts. Each body part is assigned a score between 0 and 10, with 10 indicating good posture 5 indicating fair posture, and 0 indicating poor posture. The total score is calculated by adding up the scores for all the body parts. A perfect score would be 100, indicating excellent posture.
Measured: From enrollment to the end of treatment at 6 weeks
Neck Disability Index
Neck Disability Index is 10-item questionnaire regarding functional activities of the neck. Each item has 6 categories with 0 being the least score and 5 being the highest score. The sum of the selected categories in each item are calculated and scored out of a total possible score of 50. The NDI score is assessed as a percentage if the patient skips an item.
Measured: From enrollment to the end of treatment at 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2026
- Study startFeb 2026 (estimated)
- Primary completion18 Nov 2026 (estimated)
- Study completion18 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (4)Papers the sponsor has linked to this study.
- Other trials for Upper Cross SyndromeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Ali Raza, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07435519
- Sponsor's protocol ID
- REC/RCR&AHS/24/01101
- Status last verified
- Feb 2026
- First submitted
- 22 Feb 2026
- Last updated
- 27 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Yu L-J, Kim T-H. The effect of cervical stabilization exercises with thoracic spine extension exercises on forward head posture. International Journal of Human Movement and Sports Sciences. 2021;9(5):852-7.
Mocke RCF. A Comparison of Cervical and Thoracic Manipulation, Kinesio™ Abdominal Core Taping and the Combination of the Two in the Management of Upper Cross Syndrome: University of Johannesburg (South Africa); 2019.
Kang NY, Im SC, Kim K. Effects of a combination of scapular stabilization and thoracic extension exercises for office workers with forward head posture on the craniovertebral angle, respiration, pain, and disability: A randomized-controlled trial. Turk J Phys Med Rehabil. 2021 Sep 1;67(3):291-299. doi: 10.5606/tftrd.2021.6397. eCollection 2021 Sep.
PubMed 34870115Dhage P, Anap D. Prevalence of an "Upper Crossed Syndrome in Physiotherapy College Students"-A Cross-Sectional Study. VIMS Health Science Journal. 2019;6(1):10-3.
Study at a glance
From the registry record, last updated by the sponsor on 27 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Klapp Method on Posture, Craniovertebral Angle and Disability in Upper Cross Syndrome Patients
- ClinicalTrials.gov ID
- NCT07435519
- Acronym / sponsor ID
- REC/RCR&AHS/24/01101
- Conditions
- Upper Cross Syndrome
- Keywords
- Craniovertebral Angle, Klapp Method, Neck Disability Index, Posture, Upper Cross Syndrome
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- Feb 2026 (estimated)
- Primary completion
- 18 Nov 2026 (estimated)
- Study completion
- 18 Nov 2026 (estimated)
- First posted
- 27 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was conducted to determine the effects of Klapp Method on posture, craniovertebral angle and disability in upper cross syndrome patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Klapp Method with Conventional Physical Therapy treatment | Experimental | Other: Klapp Method, Other: Conventional treatment |
| Conventional Physical Therapy Treatment | Active comparator | Other: Conventional treatment |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Both genders were included
- Participants were between the ages of 18 to 40.
- The craniovertebral angle was less than or equal to 50 degrees
- The REEDCO Posture Assessment Scale of 59% or less.
Key exclusion criteria (2 listed)
- Patients that had a history of vascular syndrome, cervical spine infection, trauma, surgery, or cervical spine damage
- Patients with inflammatory arthritis (such as rheumatoid arthritis or ankylosing spondylitis)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Klapp MethodKlapp Method: 3 sessions/week for 6 weeks Four-point walk followed by two-point walk \& back walk Breathing exercise from a kneeling position Simple bounce glide with simultaneous breathing Bunny hop Breathing exercise from a quadrupedal position: Greetings | Other | Klapp Method with Conventional Physical Therapy treatment |
| Conventional treatmentConventional Physical Therapy Treatment : 3 sessions/week for 6 weeks Hot pack 10 min Stretching exercises for Levator scapulae 3 sets for 30 sec hold each. Upper trapezius 3 sets for 30 sec hold each. Pectoralis stretches: 3 sets for 30 sec hold each. Strengthening was given to : Upper, Middle and Lower Trapezius: 10 repetitions 3 sets. Serratus anterior: 10 repetitions and 3 sets. Infraspinatus: 10 repetitions 3 sets. Deep neck flexors: 30 seconds hold 3 sets. | Other | Conventional Physical Therapy Treatment, Klapp Method with Conventional Physical Therapy treatment |
Primary outcome
Craniovertebral Angle
Time frame: From enrollment to the end of treatment at 6 weeks
Universal Goniometer is utilized to measure the craniovertebral angle. An angle between 50 to 53 degrees is considered normal
Reedco Posture Score
Time frame: From enrollment to the end of treatment at 6 weeks
Reedco Posture score is used to assess posture. The RPS includes personal information about the person being evaluated, along with a scoring system for various body parts. Each body part is assigned a score between 0 and 10, with 10 indicating good posture 5 indicating fair posture, and 0 indicating poor posture. The total score is calculated by adding up the scores for all the body parts. A perfect score would be 100, indicating excellent posture.
Neck Disability Index
Time frame: From enrollment to the end of treatment at 6 weeks
Neck Disability Index is 10-item questionnaire regarding functional activities of the neck. Each item has 6 categories with 0 being the least score and 5 being the highest score. The sum of the selected categories in each item are calculated and scored out of a total possible score of 50. The NDI score is assessed as a percentage if the patient skips an item.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Feb 2026.
- BackgroundYu L-J, Kim T-H. The effect of cervical stabilization exercises with thoracic spine extension exercises on forward head posture. International Journal of Human Movement and Sports Sciences. 2021;9(5):852-7.
- BackgroundMocke RCF. A Comparison of Cervical and Thoracic Manipulation, Kinesio™ Abdominal Core Taping and the Combination of the Two in the Management of Upper Cross Syndrome: University of Johannesburg (South Africa); 2019.
- Background: PubMed 34870115Kang NY, Im SC, Kim K. Effects of a combination of scapular stabilization and thoracic extension exercises for office workers with forward head posture on the craniovertebral angle, respiration, pain, and disability: A randomized-controlled trial. Turk J Phys Med Rehabil. 2021 Sep 1;67(3):291-299. doi: 10.5606/tftrd.2021.6397. eCollection 2021 Sep.
- BackgroundDhage P, Anap D. Prevalence of an "Upper Crossed Syndrome in Physiotherapy College Students"-A Cross-Sectional Study. VIMS Health Science Journal. 2019;6(1):10-3.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ali Raza principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Klapp Method and Conventional treatment in people with Upper Cross Syndrome, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 27 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Imran Amjad, Ph.D (+923324390125, imran.amjd@iphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Craniovertebral Angle (time frame: From enrollment to the end of treatment at 6 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07435519, which also lists 4 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Feb 2026.