OsteoporosisNCT07436000
AI-Generated Audiovisual Education and Osteoporosis Knowledge
A study testing Audio-Based Digital Education (Podcast) and Visual Digital Education (Video) in people with Osteoporosis, run by Kars State Hospital at 1 site in Turkey (Türkiye).
Trial summary
This study aims to enhance osteoporosis awareness and health literacy among individuals through audiovisual digital educational content generated using the NotebookLM artificial intelligence platform, based on educational materials developed by the International Osteoporosis Foundation. Read more about this study
- Who is it for?
- Ages 45 years and older
- Conditions the study is for
- Osteoporosis
- What is being tested?
- Audio-Based Digital Education (Podcast) and Visual Digital Education (Video)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2026to 1 Mar 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Individuals aged 45 years and older who have been diagnosed with osteoporosis or are at risk for osteoporosis
- Ability to read and understand Turkish
- Ability to use digital devices such as a smartphone, tablet, or computer
Who cannot join
- Patients with severe cognitive impairment, a diagnosis of dementia, or neurological disorders that limit effective communication
- Patients unable to follow audio or video-based educational content due to visual or hearing impairment
- Patients with serious systemic diseases other than osteoporosis (e.g., malignancy or advanced heart failure)
- Individuals who have previously participated in an osteoporosis education program
- Individuals without access to digital platforms
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Gaziantep City Hospital
Gaziantep, ŞAHİNBEY, 27470
About this study
Official title: The Effect of Artificial Intelligence-Generated Audiovisual Education on Osteoporosis Knowledge and Digital Health Literacy
This study aims to enhance osteoporosis awareness and health literacy among individuals through audiovisual digital educational content generated using the NotebookLM artificial intelligence platform, based on educational materials developed by the International Osteoporosis Foundation. In addition, the effects of these audiovisual educational materials on osteoporosis knowledge and digital health literacy will be evaluated.
Read the detailed description
Osteoporosis is a major public health problem in aging societies, leading to weakened and fragile bones and resulting in increased morbidity and mortality. Because the disease is largely asymptomatic, many individuals remain unaware of having osteoporosis until a fracture occurs. Osteoporotic fractures may cause chronic pain, functional limitations, loss of independence, and significant deterioration in quality of life. In this context, educational programs aimed at improving patients' knowledge have emerged as an important preventive strategy.
Previous studies have emphasized that osteoporosis education leads to positive changes in patients' knowledge and health-related behaviors. The International Osteoporosis Foundation (IOF) develops educational materials for patient education, provides digital resources through its official website, and publishes informative brochures. In addition, IOF supports early diagnosis, risk assessment, and preventive strategies by developing community-based awareness campaigns, online educational modules, and guideline documents for healthcare professionals. Within this framework, the easy accessibility of digital educational materials facilitates access to information and contributes to improving osteoporosis-related health literacy, particularly in aging populations.
The use of artificial intelligence-based tools has recently attracted attention as a novel approach to delivering these digital contents effectively and reaching individuals more efficiently. NotebookLM is an artificial intelligence-powered research assistant developed by Google that generates accurate and evidence-based content by learning from user-uploaded multimodal sources, such as documents, images, and videos, and by explicitly citing these sources. By enabling the transformation of uploaded content into both audiovisual formats, NotebookLM offers important opportunities for enhancing patient education. One of the key features of NotebookLM is its "source-grounded" approach. By generating information strictly based on researcher-provided sources, this approach enhances transparency, verifiability, and reliability of information in patient education processes.
In line with these features, the NotebookLM platform was utilized for the development of educational materials in this study. Patient-oriented informational pages published by the International Osteoporosis Foundation at https://www.osteoporosis.foundation/patients/about-osteoporosis were uploaded to the NotebookLM platform as source materials. Educational materials in PDF format covering the definition of osteoporosis, risk factors, diagnosis, treatment, and prevention strategies were uploaded to the platform in segments. Based on these materials, audiovisual digital educational contents were generated, including an audio-based digital content series (podcasts) and a visual digital content series (videos). The prepared podcast and video contents were reviewed by two specialist physicians, and their scientific validity and consistency with the current literature were verified.
Following the preparation and validation of these contents, the protocol for participant implementation was designed. Participants will be randomly assigned to two groups. One group will receive audio-based digital educational content (podcast series) generated via the Google NotebookLM platform, while the other group will receive visual digital educational content (video series). In both groups, the Osteoporosis Knowledge Test, the Awareness and Behavioral Intention Questionnaire, and the Health Literacy Questionnaire will be administered before and after the educational intervention to evaluate changes in knowledge level, awareness, and health-related behaviors.
In conclusion, this study aims to enhance osteoporosis awareness and health literacy among individuals through audiovisual digital educational content generated using the NotebookLM artificial intelligence platform, based on educational materials developed by the International Osteoporosis Foundation. In addition, the effects of these audiovisual educational materials on osteoporosis knowledge and digital health literacy will be evaluated.
This prospective, non-interventional survey-based study will be conducted at Gaziantep City Hospital. The patient education contents are based on secure, evidence-based sources and have been verified by physicians. The study represents a public health research initiative that poses no ethical risk, ensures the protection of personal data, and involves educational materials intended solely for educational purposes.
- Conditions
- Osteoporosis
- Being tested
- Audio-Based Digital Education (Podcast), Visual Digital Education (Video)
- Keywords
- Osteoporosis, Artificial Intelligence, Patient Education
- Medical subject headings
- Osteoporosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Audio-Based Digital Education (Podcast)Other
Participants assigned to this arm will receive audio-based digital educational content in the form of a podcast series generated using the NotebookLM artificial intelligence platform. The content is based on educational materials developed by the International Osteoporosis Foundation and covers osteoporosis definition, risk factors, diagnosis, treatment, and prevention strategies. The intervention is limited to educational content delivery and involves no clinical, laboratory, imaging, or invasive procedures.
Visual Digital Education (Video)Other
Participants assigned to this arm will receive visual digital educational content in the form of a video series generated using the NotebookLM artificial intelligence platform. The content is based on educational materials developed by the International Osteoporosis Foundation and includes information on osteoporosis definition, risk factors, diagnosis, treatment, and prevention strategies. The intervention consists solely of educational material delivery, with no clinical, laboratory, imaging, or invasive interventions involved.
| Study group | Role | What they receive |
|---|---|---|
| Audio-Based Digital Education (Podcast) | Active comparator | Not described Receives: Other: Audio-Based Digital Education (Podcast) |
| Visual Digital Education (Video) | Active comparator | Not described Receives: Other: Visual Digital Education (Video) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Osteoporosis Knowledge Level
Change in osteoporosis knowledge level assessed using the Osteoporosis Knowledge Test, administered before and after the educational intervention.
Measured: Baseline (pre-intervention) and immediately after completion of the educational intervention
Secondary outcomes (2)
Change in Osteoporosis Awareness and Behavioral Intention
Change in osteoporosis awareness and behavioral intention evaluated using the Awareness and Behavioral Intention Questionnaire before and after the educational intervention. Assessment is limited to self-reported questionnaire data.
Measured: Baseline and immediately after completion of the educational intervention
Change in Digital Health Literacy Level
Change in digital health literacy level assessed using the Health Literacy Questionnaire before and after the educational intervention.
Measured: Baseline and immediately after completion of the educational intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2026
- Study start1 Jan 2026
- Primary completion1 Mar 2026
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for OsteoporosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kars State Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Fatih Bagcier, Kars State Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07436000
- Sponsor's protocol ID
- Gaziantep Şehir Hastanesi
- Status last verified
- Aug 2026
- First submitted
- 21 Feb 2026
- Last updated
- 14 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Artificial Intelligence-Generated Audiovisual Education on Osteoporosis Knowledge and Digital Health Literacy
- ClinicalTrials.gov ID
- NCT07436000
- Acronym / sponsor ID
- Gaziantep Şehir Hastanesi
- Conditions
- Osteoporosis
- Keywords
- Osteoporosis, Artificial Intelligence, Patient Education
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Kars State HospitalUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 1 Mar 2026 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 27 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to enhance osteoporosis awareness and health literacy among individuals through audiovisual digital educational content generated using the NotebookLM artificial intelligence platform, based on educational materials developed by the International Osteoporosis Foundation. In addition, the effects of these audiovisual educational materials on osteoporosis knowledge and digital health literacy will be evaluated.
Detailed description
Osteoporosis is a major public health problem in aging societies, leading to weakened and fragile bones and resulting in increased morbidity and mortality. Because the disease is largely asymptomatic, many individuals remain unaware of having osteoporosis until a fracture occurs. Osteoporotic fractures may cause chronic pain, functional limitations, loss of independence, and significant deterioration in quality of life. In this context, educational programs aimed at improving patients' knowledge have emerged as an important preventive strategy.
Previous studies have emphasized that osteoporosis education leads to positive changes in patients' knowledge and health-related behaviors. The International Osteoporosis Foundation (IOF) develops educational materials for patient education, provides digital resources through its official website, and publishes informative brochures. In addition, IOF supports early diagnosis, risk assessment, and preventive strategies by developing community-based awareness campaigns, online educational modules, and guideline documents for healthcare professionals. Within this framework, the easy accessibility of digital educational materials facilitates access to information and contributes to improving osteoporosis-related health literacy, particularly in aging populations.
The use of artificial intelligence-based tools has recently attracted attention as a novel approach to delivering these digital contents effectively and reaching individuals more efficiently. NotebookLM is an artificial intelligence-powered research assistant developed by Google that generates accurate and evidence-based content by learning from user-uploaded multimodal sources, such as documents, images, and videos, and by explicitly citing these sources. By enabling the transformation of uploaded content into both audiovisual formats, NotebookLM offers important opportunities for enhancing patient education. One of the key features of NotebookLM is its "source-grounded" approach. By generating information strictly based on researcher-provided sources, this approach enhances transparency, verifiability, and reliability of information in patient education processes.
In line with these features, the NotebookLM platform was utilized for the development of educational materials in this study. Patient-oriented informational pages published by the International Osteoporosis Foundation at https://www.osteoporosis.foundation/patients/about-osteoporosis were uploaded to the NotebookLM platform as source materials. Educational materials in PDF format covering the definition of osteoporosis, risk factors, diagnosis, treatment, and prevention strategies were uploaded to the platform in segments. Based on these materials, audiovisual digital educational contents were generated, including an audio-based digital content series (podcasts) and a visual digital content series (videos). The prepared podcast and video contents were reviewed by two specialist physicians, and their scientific validity and consistency with the current literature were verified.
Following the preparation and validation of these contents, the protocol for participant implementation was designed. Participants will be randomly assigned to two groups. One group will receive audio-based digital educational content (podcast series) generated via the Google NotebookLM platform, while the other group will receive visual digital educational content (video series). In both groups, the Osteoporosis Knowledge Test, the Awareness and Behavioral Intention Questionnaire, and the Health Literacy Questionnaire will be administered before and after the educational intervention to evaluate changes in knowledge level, awareness, and health-related behaviors.
In conclusion, this study aims to enhance osteoporosis awareness and health literacy among individuals through audiovisual digital educational content generated using the NotebookLM artificial intelligence platform, based on educational materials developed by the International Osteoporosis Foundation. In addition, the effects of these audiovisual educational materials on osteoporosis knowledge and digital health literacy will be evaluated.
This prospective, non-interventional survey-based study will be conducted at Gaziantep City Hospital. The patient education contents are based on secure, evidence-based sources and have been verified by physicians. The study represents a public health research initiative that poses no ethical risk, ensures the protection of personal data, and involves educational materials intended solely for educational purposes.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Audio-Based Digital Education (Podcast) | Active comparator | Other: Audio-Based Digital Education (Podcast) |
| Visual Digital Education (Video) | Active comparator | Other: Visual Digital Education (Video) |
Who may qualify
- Ages
- 45 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Individuals aged 45 years and older who have been diagnosed with osteoporosis or are at risk for osteoporosis
- Ability to read and understand Turkish
- Ability to use digital devices such as a smartphone, tablet, or computer
Key exclusion criteria (5 listed)
- Patients with severe cognitive impairment, a diagnosis of dementia, or neurological disorders that limit effective communication
- Patients unable to follow audio or video-based educational content due to visual or hearing impairment
- Patients with serious systemic diseases other than osteoporosis (e.g., malignancy or advanced heart failure)
- Individuals who have previously participated in an osteoporosis education program
- Individuals without access to digital platforms
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Audio-Based Digital Education (Podcast)Participants assigned to this arm will receive audio-based digital educational content in the form of a podcast series generated using the NotebookLM artificial intelligence platform. The content is based on educational materials developed by the International Osteoporosis Foundation and covers osteoporosis definition, risk factors, diagnosis, treatment, and prevention strategies. The intervention is limited to educational content delivery and involves no clinical, laboratory, imaging, or invasive procedures. | Other | Audio-Based Digital Education (Podcast) |
| Visual Digital Education (Video)Participants assigned to this arm will receive visual digital educational content in the form of a video series generated using the NotebookLM artificial intelligence platform. The content is based on educational materials developed by the International Osteoporosis Foundation and includes information on osteoporosis definition, risk factors, diagnosis, treatment, and prevention strategies. The intervention consists solely of educational material delivery, with no clinical, laboratory, imaging, or invasive interventions involved. | Other | Visual Digital Education (Video) |
Primary outcome
Change in Osteoporosis Knowledge Level
Time frame: Baseline (pre-intervention) and immediately after completion of the educational intervention
Change in osteoporosis knowledge level assessed using the Osteoporosis Knowledge Test, administered before and after the educational intervention.
2 secondary outcomes
Change in Osteoporosis Awareness and Behavioral Intention
Time frame: Baseline and immediately after completion of the educational intervention
Change in Digital Health Literacy Level
Time frame: Baseline and immediately after completion of the educational intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Audio-Based Digital Education (Podcast) and Visual Digital Education (Video) in people with Osteoporosis, run by Kars State Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Osteoporosis Knowledge Level (time frame: Baseline (pre-intervention) and immediately after completion of the educational intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.