Chronic Ankle InstabilityNCT07439861
The Effect of Cognitive Dual-Task on Athletic Performance Parameters in Volleyball Players With and Without Chronic Ankle Instability
An observational study of Chronic Ankle Instability and Chronic Ankle Instability, CAI, run by Hacettepe University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to investigate the effect of the cognitive dual-task on athletic performance parameters in volleyball players with and without chronic ankle instability. In addition, it will examine how a pathology in the lower extremity affects upper extremity function. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Chronic Ankle Instability, Chronic Ankle Instability, CAI, Volleyball
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 23 Mar 2026to 5 Feb 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Volleyball players with chronic ankle instability (CAI)
Who may be able to join
- Chronic Ankle Instability Group Patients who meet all of the following criteria will be included in the study. The inclusion criteria defined by the International Ankle Consortium will be accepted.
- Individuals must have been actively participating in the sport of volleyball for at least 5 years,
- Individuals' first ankle sprain history must have occurred at least 1 year prior to the study and must have been associated with inflammatory symptoms (pain, swelling),
- The most recent ankle sprain must have occurred 3 months or more before the start date of the study,
- Athletes must have experienced a sensation of giving way at least twice within the past 6 months,
- Athletes must have no history of ankle fracture,
Show all 16Show fewer
- Athletes must not have undergone any surgical procedures affecting sensorimotor function in the lower extremity and must have no internal diseases,
- The score of the Identification of Functional Ankle Instability questionnaire must be greater than 11,
- The Foot and Ankle Ability Measure score must be less than 90%,
- The Foot and Ankle Ability Measure Sports subscale score must be less than 80%,
- The Cumberland Ankle Instability Tool (CAIT) score must be less than 24,
- The Foot and Ankle Outcome Score must be less than 75% in three or more categories.
- Participation in volleyball training at least 3 days per week for 1 hour for a minimum of 5 years,
- A Cumberland Ankle Instability Tool score of 25 or higher,
- A Tegner activity level of 4 or higher,
- Absence of any systemic disease that could interfere with measurements.
Who cannot join
- Presence of rheumatic, neurological, or cardiovascular disease,
- History of ankle surgery,
- Musculoskeletal injury affecting the lower extremity within the last 6 months,
- Individuals who do not agree to participate in the study.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Nurefsan BAYRAK, PT contact
Turkey (Türkiye)1 site
Hacettepe University
Ankara
Aynur DEMIREL, PT, PhD, Assoc. Prof., +905545295057, aynur.demirel@hacettepe.edu.tr
Aynur Demirel, PT, PhD, Assoc. Prof.
About this study
Official title: Investigation of the Effect of Cognitive Dual-Task on Athletic Performance Parameters in Volleyball Players With and Without Chronic Ankle Instability
The aim of this study is to investigate the effect of the cognitive dual-task on athletic performance parameters in volleyball players with and without chronic ankle instability. In addition, it will examine how a pathology in the lower extremity affects upper extremity function.
Read the detailed description
This project is a cross-sectional and comparative study designed to investigate the effects of cognitive dual-task conditions on athletic performance parameters in volleyball players with and without chronic ankle instability (CAI). Chronic ankle instability is characterized by recurrent ankle sprains and a sensation of "giving way," and may lead to impairments in sensorimotor control, postural stability, and neuromuscular functions. Current approaches indicate that this pathology affects not only peripheral structures but also the central nervous system and cognitive processes. However, how CAI under cognitive load is reflected in upper extremity function through the kinetic chain has not been sufficiently investigated.
Volleyball players aged between 18 and 25 years who are actively playing volleyball will be included in the study. Participants will be divided into two main groups: those with CAI and a healthy control group; the CAI group will also be classified as unilateral and bilateral. In all participants, static balance, dynamic balance, lower extremity strength, ankle dorsiflexion range of motion, upper extremity functional performance, and spatiotemporal parameters of running will be evaluated under single-task and cognitive dual-task conditions.
The originality of this study lies in addressing not only lower extremity functions in CAI but also upper extremity performance and its interaction with cognitive processes through the kinetic chain, using a holistic approach. The findings obtained are expected to clarify the role of cognitive load on athletic performance in individuals with CAI and to contribute to the planning of more functional and holistic athlete assessment and rehabilitation programs.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| volleyball players | volleyball players with CAI - volleyball players without CAI volleyball players with unilateral CAI - volleyball players with bilateral CAI |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cognitive test protocol
This protocol is designed to assess participants' attention, concentration, working memory, and mental calculation abilities. It is particularly used to evaluate the cognitive load accompanying motor performance within the dual-task paradigm. First, the test will be explained to the participants, after which a 20-second practice period will be provided. Subsequently, starting from a randomly determined number between 200 and 250 (excluding numbers ending in 7 and 0), participants will be asked to continue by verbally subtracting 7. While performing this subtraction, participants will be instructed to do so as accurately as possible, and the errors made during the test will be recorded.
Measured: 1 day
Single-Leg Balance Test
This test evaluates static postural control based on the number of errors made. Protocol Participants will be asked to stand barefoot on one leg with their hands placed on their hips. The supporting knee will be slightly flexed (approximately 10°), hands on the waist, and eyes closed, and they will be asked to maintain the balance position. Participants will attempt to maintain balance in this position for 20 seconds. Prior to the test, two practice trials will be performed for each foot for familiarization purposes.
Test Termination The trial will be considered invalid and repeated if the participant removes their hands from their hips, flexes or abducts the thigh more than 30°, lifts the heel or forefoot of the supporting foot off the ground, is unable to maintain the test position for more than 5 seconds, or opens their eyes.
Measurement The test will be performed once for each lower extremity. The total number of errors made for each leg will be counted and recorded by the assesso
Measured: 1 day
Side Hop Test
Protocol The test will be performed by having participants hop laterally on one leg across a distance of 30 cm. One repetition is defined as hopping 30 cm laterally and then returning to the starting point in the same manner. Each participant will be asked to complete 10 repetitions of this movement as quickly as possible.
Test Termination The trial will be considered invalid and repeated if the participant falls, places the contralateral foot on the ground for support, or fails to fully exceed the 30 cm distance during hopping.
Measurement The time (seconds) required to complete 10 valid repetitions will be recorded. The validity and reliability of the test were found to be good, with a value of 0.84, as reported by Caffrey et al.
Measured: 1 day
Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST)
Protocol The participant will assume a push-up position with the hands placed on two parallel lines spaced 91.4 cm (36 inches) apart. During the test, the participant will lift one hand to touch the opposite line and then repeat the same movement with the other hand, performing as many touches as possible.
Measurement The total number of touches performed within 15 seconds will be recorded. The test will be conducted in three trials with 45 seconds of rest between trials, and the average of these three trials will be used as the final score.
The validity and reliability of the test were evaluated by Lee et al. and reported as 0.97.
Measured: 1 day
Spiking (Attack) Test
A target measuring 2 meters in height and 1 meter in width will be placed on a wall located 7 meters away from the player. This target will be horizontally divided into five equal sections of 20 cm each. A coach will stand approximately 5 meters away from the approaching player to perform the spike and will deliver an overhead pass to the player. The players' task will be to perform a spike approach and hit the ball toward this target. Scoring will be performed as follows: players who hit the central 20 cm section will receive 5 points; players who hit the two 20 cm sections adjacent to the central section will receive 3 points; and players who hit the two outermost 20 cm sections of the target will receive 1 point. If the ball successfully hits the boundary between two adjacent scoring zones, scores of 2 or 4 points will be recorded, respectively. Each player will perform 6 trials, and the total score obtained from these trials will be recorded as the player's "spiking accuracy score
Measured: 1 day
Forearm Pass (Passing) Test
Players' passing skills will be assessed by their ability to return a pass to a target positioned on the net, 2 m from the right sideline. The primary target (1.6 m high × 2.3 m wide) represents the approximate setter position during match play. A coach, positioned in the service area approximately 1 m above ground and 10 m from the player, delivers an overhead pass simulating a spiked ball. Players attempt to pass the ball to a teammate within the primary target area using an overhead forearm pass. Successful passes into this area receive 2 points.
A secondary target area (3 m deep × 4.1 m wide) is defined for playable but less accurate passes and is awarded 1 point. Passes outside both areas receive 0 points. Each player completes six trials, and the total score represents the "passing accuracy score." The test demonstrates high reliability, with a reported test-retest coefficient of 0.94.
Measured: 1 day
Setting Test
Players' setting skills will be evaluated based on their ability to set the ball toward a circular target (80 cm diameter) positioned at net height, 5.5 m from the setter. This location represents the typical position of an attacker preparing to spike. A coach positioned 5 m from the setter delivers an overhead pass. Players attempt to set the ball into the target.
Scoring is as follows: successful passes through the target receive 3 points; passes contacting the edge receive 2 points; and passes crossing the net within 2.3 m of the net (approximately 1.5 m from the target center) receive 1 point. No points are awarded for unsuccessful attempts. Each player performs six trials, and the total score is recorded as the "setting accuracy score." The test shows high reliability, with a test-retest coefficient of 0.88.
Measured: 1 day
Serving Test
Players' serving skills will be evaluated based on their performance of serving the ball into a designated target area (9 meters in width) located in the opponent's court from the standard serving position. If the player successfully delivers the ball into the designated area (opponent's court), 1 point will be recorded. If the serve fails to reach the target area, such as landing outside the opponent's court or contacting the net, 0 points will be awarded. The total score obtained from 6 serving trials performed by each player will be recorded as the player's "serving accuracy score" (52).
The validity and reliability of the test were reported by Gabbett et al., with a test-retest reliability of 0.94.
Measured: 1 day
Secondary outcomes (3)
Countermovement Jump Test
Protocol Participants will start in an upright standing position with their hands placed on their hips, then they will be instructed to flex their knees as quickly as possible (approximately 90°) and, in the subsequent concentric phase, to jump as high as possible without performing any arm movement. Participants will be instructed to leave the ground by extending their knees and ankles during the jump and to land in a similarly extended position, and they will be asked to perform consecutive jumps as high and as quickly as possible for 15 seconds.
Measurement Three trials will be obtained with 30-second rest intervals between trials. Using the OptoGait photoelectric system (Microgate, Italy), the flight time (ms) of each jump will be recorded and converted into jump height (cm) by the system software. The average jump height of all jumps recorded within the 15-second period will be used as the performance score.
Measured: 1 day
Squat Jump Test
Participants will start in an upright standing position with their hands placed on their hips, then they will be asked to flex their knees and maintain a predetermined knee position (approximately 90°). While the knees are held in the flexed position, the assessor will count for 3 seconds, after which participants will be instructed to jump as high as possible without performing any arm movement. Participants will be instructed to leave the ground by extending their knees and ankles during the jump and to land in a similarly extended position, and they will be asked to perform consecutive jumps as high and as quickly as possible for 15 seconds.
Three trials will be obtained with 30-second rest intervals between trials. Using the OptoGait photoelectric system, the flight time (ms) of each jump will be recorded and converted into jump height (cm) by the system software. The average jump height of all jumps recorded within the 15-second period will be used as the performance score.
Measured: 1 day
Running Test
A pair of OptoGait photoelectric systems (Microgate, Bolzano, Italy), each one meter in length, will be placed on both sides of a treadmill, at the same level as the contact surfaces. Participants will be asked to warm up by walking on the treadmill at their own comfortable, natural walking speeds and to become familiar with the treadmill. Data collection will be initiated after the participant reaches a constant speed of 2.78 m/s, and recordings will be obtained for a total duration of 1 minute, with the final 30 seconds taken into consideration.
Measured Parameters Ground contact time, step angle, flight time, step length, stride length, step frequency, and cadence.
The validity and reliability of the test were evaluated by Garcia-Pinillos et al., who reported a high level of agreement between systems in all examined spatiotemporal parameters (ICC > 0.89).
Measured: 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2026
- Study start23 Mar 2026 (estimated)
- Primary completion5 Aug 2027 (estimated)
- Study completion5 Feb 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Ankle InstabilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hacettepe University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Aynur Demirel, Hacettepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07439861
- Sponsor's protocol ID
- FTREK25/187
- Status last verified
- Feb 2026
- First submitted
- 23 Feb 2026
- Last updated
- 27 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Effect of Cognitive Dual-Task on Athletic Performance Parameters in Volleyball Players With and Without Chronic Ankle Instability
- ClinicalTrials.gov ID
- NCT07439861
- Acronym / sponsor ID
- FTREK25/187
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Hacettepe UniversityUniversity, hospital or other
- Study start
- 23 Mar 2026 (estimated)
- Primary completion
- 5 Aug 2027 (estimated)
- Study completion
- 5 Feb 2028 (estimated)
- First posted
- 27 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to investigate the effect of the cognitive dual-task on athletic performance parameters in volleyball players with and without chronic ankle instability. In addition, it will examine how a pathology in the lower extremity affects upper extremity function.
Detailed description
This project is a cross-sectional and comparative study designed to investigate the effects of cognitive dual-task conditions on athletic performance parameters in volleyball players with and without chronic ankle instability (CAI). Chronic ankle instability is characterized by recurrent ankle sprains and a sensation of "giving way," and may lead to impairments in sensorimotor control, postural stability, and neuromuscular functions. Current approaches indicate that this pathology affects not only peripheral structures but also the central nervous system and cognitive processes. However, how CAI under cognitive load is reflected in upper extremity function through the kinetic chain has not been sufficiently investigated.
Volleyball players aged between 18 and 25 years who are actively playing volleyball will be included in the study. Participants will be divided into two main groups: those with CAI and a healthy control group; the CAI group will also be classified as unilateral and bilateral. In all participants, static balance, dynamic balance, lower extremity strength, ankle dorsiflexion range of motion, upper extremity functional performance, and spatiotemporal parameters of running will be evaluated under single-task and cognitive dual-task conditions.
The originality of this study lies in addressing not only lower extremity functions in CAI but also upper extremity performance and its interaction with cognitive processes through the kinetic chain, using a holistic approach. The findings obtained are expected to clarify the role of cognitive load on athletic performance in individuals with CAI and to contribute to the planning of more functional and holistic athlete assessment and rehabilitation programs.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| volleyball players | – | –volleyball players with CAI - volleyball players without CAI volleyball players with unilateral CAI - volleyball players with bilateral CAI |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Volleyball players with chronic ankle instability (CAI)
Key inclusion criteria (16 listed)
- Chronic Ankle Instability Group Patients who meet all of the following criteria will be included in the study. The inclusion criteria defined by the International Ankle Consortium will be accepted.
- Participation in volleyball training at least 3 days per week for 1 hour for a minimum of 5 years,
- A Cumberland Ankle Instability Tool score of 25 or higher,
- A Tegner activity level of 4 or higher,
- Absence of any systemic disease that could interfere with measurements.
Key exclusion criteria (4 listed)
- Presence of rheumatic, neurological, or cardiovascular disease,
- History of ankle surgery,
- Musculoskeletal injury affecting the lower extremity within the last 6 months,
- Individuals who do not agree to participate in the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Cognitive test protocol
Time frame: 1 day
This protocol is designed to assess participants' attention, concentration, working memory, and mental calculation abilities. It is particularly used to evaluate the cognitive load accompanying motor performance within the dual-task paradigm. First, the test will be explained to the participants, after which a 20-second practice period will be provided. Subsequently, starting from a randomly determined number between 200 and 250 (excluding numbers ending in 7 and 0), participants will be asked to continue by verbally subtracting 7. While performing this subtraction, participants will be instructed to do so as accurately as possible, and the errors made during the test will be recorded.
Single-Leg Balance Test
Time frame: 1 day
This test evaluates static postural control based on the number of errors made. Protocol Participants will be asked to stand barefoot on one leg with their hands placed on their hips. The supporting knee will be slightly flexed (approximately 10°), hands on the waist, and eyes closed, and they will be asked to maintain the balance position. Participants will attempt to maintain balance in this position for 20 seconds. Prior to the test, two practice trials will be performed for each foot for familiarization purposes. Test Termination The trial will be considered invalid and repeated if the participant removes their hands from their hips, flexes or abducts the thigh more than 30°, lifts the heel or forefoot of the supporting foot off the ground, is unable to maintain the test position for more than 5 seconds, or opens their eyes. Measurement The test will be performed once for each lower extremity. The total number of errors made for each leg will be counted and recorded by the assesso
Side Hop Test
Time frame: 1 day
Protocol The test will be performed by having participants hop laterally on one leg across a distance of 30 cm. One repetition is defined as hopping 30 cm laterally and then returning to the starting point in the same manner. Each participant will be asked to complete 10 repetitions of this movement as quickly as possible. Test Termination The trial will be considered invalid and repeated if the participant falls, places the contralateral foot on the ground for support, or fails to fully exceed the 30 cm distance during hopping. Measurement The time (seconds) required to complete 10 valid repetitions will be recorded. The validity and reliability of the test were found to be good, with a value of 0.84, as reported by Caffrey et al.
Closed Kinetic Chain Upper Extremity Stability Test (CKCUEST)
Time frame: 1 day
Protocol The participant will assume a push-up position with the hands placed on two parallel lines spaced 91.4 cm (36 inches) apart. During the test, the participant will lift one hand to touch the opposite line and then repeat the same movement with the other hand, performing as many touches as possible. Measurement The total number of touches performed within 15 seconds will be recorded. The test will be conducted in three trials with 45 seconds of rest between trials, and the average of these three trials will be used as the final score. The validity and reliability of the test were evaluated by Lee et al. and reported as 0.97.
Spiking (Attack) Test
Time frame: 1 day
A target measuring 2 meters in height and 1 meter in width will be placed on a wall located 7 meters away from the player. This target will be horizontally divided into five equal sections of 20 cm each. A coach will stand approximately 5 meters away from the approaching player to perform the spike and will deliver an overhead pass to the player. The players' task will be to perform a spike approach and hit the ball toward this target. Scoring will be performed as follows: players who hit the central 20 cm section will receive 5 points; players who hit the two 20 cm sections adjacent to the central section will receive 3 points; and players who hit the two outermost 20 cm sections of the target will receive 1 point. If the ball successfully hits the boundary between two adjacent scoring zones, scores of 2 or 4 points will be recorded, respectively. Each player will perform 6 trials, and the total score obtained from these trials will be recorded as the player's "spiking accuracy score
Forearm Pass (Passing) Test
Time frame: 1 day
Players' passing skills will be assessed by their ability to return a pass to a target positioned on the net, 2 m from the right sideline. The primary target (1.6 m high × 2.3 m wide) represents the approximate setter position during match play. A coach, positioned in the service area approximately 1 m above ground and 10 m from the player, delivers an overhead pass simulating a spiked ball. Players attempt to pass the ball to a teammate within the primary target area using an overhead forearm pass. Successful passes into this area receive 2 points. A secondary target area (3 m deep × 4.1 m wide) is defined for playable but less accurate passes and is awarded 1 point. Passes outside both areas receive 0 points. Each player completes six trials, and the total score represents the "passing accuracy score." The test demonstrates high reliability, with a reported test-retest coefficient of 0.94.
Setting Test
Time frame: 1 day
Players' setting skills will be evaluated based on their ability to set the ball toward a circular target (80 cm diameter) positioned at net height, 5.5 m from the setter. This location represents the typical position of an attacker preparing to spike. A coach positioned 5 m from the setter delivers an overhead pass. Players attempt to set the ball into the target. Scoring is as follows: successful passes through the target receive 3 points; passes contacting the edge receive 2 points; and passes crossing the net within 2.3 m of the net (approximately 1.5 m from the target center) receive 1 point. No points are awarded for unsuccessful attempts. Each player performs six trials, and the total score is recorded as the "setting accuracy score." The test shows high reliability, with a test-retest coefficient of 0.88.
Serving Test
Time frame: 1 day
Players' serving skills will be evaluated based on their performance of serving the ball into a designated target area (9 meters in width) located in the opponent's court from the standard serving position. If the player successfully delivers the ball into the designated area (opponent's court), 1 point will be recorded. If the serve fails to reach the target area, such as landing outside the opponent's court or contacting the net, 0 points will be awarded. The total score obtained from 6 serving trials performed by each player will be recorded as the player's "serving accuracy score" (52). The validity and reliability of the test were reported by Gabbett et al., with a test-retest reliability of 0.94.
3 secondary outcomes
Countermovement Jump Test
Time frame: 1 day
Squat Jump Test
Time frame: 1 day
Running Test
Time frame: 1 day
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Feb 2026.
- Individual participant dataSharing planned: No
Related trials for Chronic Ankle Instability
Recruiting
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Ankle Sprains, Ankle Sprain Strain
Recruiting
Functional Biomechanical Analysis in Patients Who Underwent Lateral Ankle Ligament Repair With Augmentation
Chronic Lateral Ankle Instability
Not yet recruiting
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
Chronic Ankle Instability, Ankle Sprain
Recruiting
Comparison of the Effects of Hip and Ankle Focused Progressive Exercise Training on Lower Extremity Function in Athletes With Chronic Ankle Instability
Ankle Sprains
Recruiting
Brostrom Chronic Lateral Ankle Instability Repairs Augmented With BioBrace®
Lateral Ankle Instability, Chronic Lateral Ankle Instability
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nurefsan BAYRAK, PT contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Chronic Ankle Instability and Chronic Ankle Instability, CAI, run by Hacettepe University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 16 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 27 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Aynur DEMIREL, PT, PhD, Assoc. Prof. (+905545295057, aynur.demirel@hacettepe.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cognitive test protocol (time frame: 1 day). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Feb 2026.